UY24434A1 - Nuevos imidazoles sustituidos con cicloalquilo - Google Patents
Nuevos imidazoles sustituidos con cicloalquiloInfo
- Publication number
- UY24434A1 UY24434A1 UY24434A UY24434A UY24434A1 UY 24434 A1 UY24434 A1 UY 24434A1 UY 24434 A UY24434 A UY 24434A UY 24434 A UY24434 A UY 24434A UY 24434 A1 UY24434 A1 UY 24434A1
- Authority
- UY
- Uruguay
- Prior art keywords
- cycloalkyl
- naphth
- compounds
- new imidazoles
- replaced
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Abstract
Se describe un procedimiento para preparar imidazoles sustituidos con cicloalquilo de fórmula (I) (figura 1), en la cual: R1 es 4-piridilo, pirimidinilo, quinolilo, isoquinolinilo, quinazolin-4-ilo, 1-imidazolilo o 1-bencimidazolilo; R4 es fenilo, naft-1-ilo o naft-2-ilo, o un heteroarilo, R2 es un cicloalquilo, o cicloalquil-alquilo, o una de sus sales farmacéuticamente aceptables. Los compuestos son capaces de inhibir las proteínas proinflamatorias inducibles, tales como COX-2. Por tanto, dichos compuestos son útiles en el tratamiento de enfermedades inflamatorias. Ej. no limitante: 1-(4-oxociclohexil)-4-(4-fluorofenil)-5-[2-metoxi-pirimidin-4-il]imidazol
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US1001096P | 1996-01-11 | 1996-01-11 |
Publications (1)
Publication Number | Publication Date |
---|---|
UY24434A1 true UY24434A1 (es) | 1997-06-06 |
Family
ID=21743297
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
UY24434A UY24434A1 (es) | 1996-01-11 | 1997-01-08 | Nuevos imidazoles sustituidos con cicloalquilo |
Country Status (24)
Country | Link |
---|---|
US (1) | US6329526B1 (es) |
EP (1) | EP0889726B1 (es) |
JP (1) | JP2000503304A (es) |
CN (1) | CN1213305A (es) |
AP (1) | AP9700912A0 (es) |
AR (1) | AR005434A1 (es) |
AT (1) | ATE276248T1 (es) |
AU (1) | AU715315B2 (es) |
BR (1) | BR9708149A (es) |
CZ (1) | CZ218198A3 (es) |
DE (1) | DE69730704T2 (es) |
ES (1) | ES2229335T3 (es) |
HU (1) | HUP9901233A2 (es) |
ID (1) | ID18759A (es) |
IL (1) | IL125224A0 (es) |
MA (1) | MA24055A1 (es) |
MX (1) | MX9805628A (es) |
NO (1) | NO983182L (es) |
NZ (1) | NZ330889A (es) |
PL (1) | PL327939A1 (es) |
TR (1) | TR199801350T2 (es) |
UY (1) | UY24434A1 (es) |
WO (1) | WO1997025048A1 (es) |
ZA (1) | ZA97173B (es) |
Families Citing this family (55)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5916891A (en) | 1992-01-13 | 1999-06-29 | Smithkline Beecham Corporation | Pyrimidinyl imidazoles |
ZA9610687B (en) * | 1995-12-22 | 1997-09-29 | Smithkline Beecham Corp | Novel synthesis. |
ATE247470T1 (de) * | 1996-01-11 | 2003-09-15 | Smithkline Beecham Corp | Neue substituierte imidazolverbindungen |
AP9700912A0 (en) | 1996-01-11 | 1997-01-31 | Smithkline Beecham Corp | Novel cycloalkyl substituted imidazoles |
US6046208A (en) * | 1996-01-11 | 2000-04-04 | Smithkline Beecham Corporation | Substituted imidazole compounds |
US6096739A (en) * | 1996-03-25 | 2000-08-01 | Smithkline Beecham Corporation | Treatment for CNS injuries |
US6235760B1 (en) * | 1996-03-25 | 2001-05-22 | Smithkline Beecham Corporation | Treatment for CNS injuries |
WO1998007425A1 (en) | 1996-08-21 | 1998-02-26 | Smithkline Beecham Corporation | Imidazole compounds, compositions and use |
US5929076A (en) * | 1997-01-10 | 1999-07-27 | Smithkline Beecham Corporation | Cycloalkyl substituted imidazoles |
JP2002502380A (ja) | 1997-05-22 | 2002-01-22 | ジー.ディー.サール アンド カンパニー | p38キナーゼ阻害剤としてのピラゾール誘導体 |
US6514977B1 (en) | 1997-05-22 | 2003-02-04 | G.D. Searle & Company | Substituted pyrazoles as p38 kinase inhibitors |
US6979686B1 (en) | 2001-12-07 | 2005-12-27 | Pharmacia Corporation | Substituted pyrazoles as p38 kinase inhibitors |
JP2002504909A (ja) | 1997-06-13 | 2002-02-12 | スミスクライン・ビーチャム・コーポレイション | 新規な置換ピラゾールおよびピラゾリン化合物 |
AU8154998A (en) | 1997-06-19 | 1999-01-04 | Smithkline Beecham Corporation | Novel aryloxy substituted pyrimidine imidazole compounds |
WO1999001452A1 (en) | 1997-07-02 | 1999-01-14 | Smithkline Beecham Corporation | Novel cycloalkyl substituted imidazoles |
US6489325B1 (en) | 1998-07-01 | 2002-12-03 | Smithkline Beecham Corporation | Substituted imidazole compounds |
TW517055B (en) | 1997-07-02 | 2003-01-11 | Smithkline Beecham Corp | Novel substituted imidazole compounds |
US6562832B1 (en) | 1997-07-02 | 2003-05-13 | Smithkline Beecham Corporation | Substituted imidazole compounds |
US7301021B2 (en) | 1997-07-02 | 2007-11-27 | Smithkline Beecham Corporation | Substituted imidazole compounds |
WO1999017776A1 (en) | 1997-10-08 | 1999-04-15 | Smithkline Beecham Corporation | Novel cycloalkenyl substituted compounds |
AU1924699A (en) | 1997-12-19 | 1999-07-12 | Smithkline Beecham Corporation | Compounds of heteroaryl substituted imidazole, their pharmaceutical compositionsand uses |
US6096899A (en) * | 1998-04-14 | 2000-08-01 | The Regents Of The University Of Michigan | Cylic imidazole compounds having relatively low hydrogen content and relatively high nitrogen content and polymers formed therefrom |
GB9809869D0 (en) * | 1998-05-09 | 1998-07-08 | Medical Res Council | Inhibition of protein kinases |
EP1080087A4 (en) | 1998-05-22 | 2001-11-21 | Smithkline Beecham Corp | NEW 2-ALKYL-SUBSTITUTED IMIDAZOLES |
US6858617B2 (en) | 1998-05-26 | 2005-02-22 | Smithkline Beecham Corporation | Substituted imidazole compounds |
EP1112070B1 (en) | 1998-08-20 | 2004-05-12 | Smithkline Beecham Corporation | Novel substituted triazole compounds |
WO2000025791A1 (en) | 1998-11-04 | 2000-05-11 | Smithkline Beecham Corporation | Pyridin-4-yl or pyrimidin-4-yl substituted pyrazines |
US6239279B1 (en) | 1998-12-16 | 2001-05-29 | Smithkline Beecham Corporation | Synthesis for 4-aryl-5-pyrimidine imidazole substituted derivatives |
US6930101B1 (en) | 1999-05-17 | 2005-08-16 | The Regents Of The University Of California | Thiazolopyrimidines useful as TNFα inhibitors |
TR200200673T2 (tr) * | 1999-09-17 | 2002-12-23 | Smithkline Beecham Corporation | Rinovirüs enfeksiyonlarında csaıd'lerin kullanılması |
JP2003514900A (ja) | 1999-11-23 | 2003-04-22 | スミスクライン・ビーチャム・コーポレイション | CSBP/p38キナーゼ阻害剤としての3,4−ジヒドロ−(1H)−キナゾリン−2−オン化合物 |
EP1233950B1 (en) | 1999-11-23 | 2005-10-05 | Smithkline Beecham Corporation | 3,4-DIHYDRO-(1H)QUINAZOLIN-2-ONE COMPOUNDS AS CSBP/P39 kINASE INHIBITORS |
US6759410B1 (en) | 1999-11-23 | 2004-07-06 | Smithline Beecham Corporation | 3,4-dihydro-(1H)-quinazolin-2-ones and their use as CSBP/p38 kinase inhibitors |
US7235551B2 (en) | 2000-03-02 | 2007-06-26 | Smithkline Beecham Corporation | 1,5-disubstituted-3,4-dihydro-1h-pyrimido[4,5-d]pyrimidin-2-one compounds and their use in treating csbp/p38 kinase mediated diseases |
US6673818B2 (en) | 2001-04-20 | 2004-01-06 | Pharmacia Corporation | Fluoro-substituted benzenesulfonyl compounds for the treatment of inflammation |
US7473695B2 (en) * | 2001-10-22 | 2009-01-06 | Mitsubishi Tanabe Pharma Corporation | 4-imidazolin-2-one compounds |
AU2003245989A1 (en) | 2002-07-09 | 2004-01-23 | Boehringer Ingelheim Pharma Gmbh And Co. Kg | Pharmaceutical compositions of anticholinergics and p38 kinase inhibitors in the treatment of respiratory diseases |
PT1608407E (pt) * | 2003-03-20 | 2006-12-29 | Pharmacia Corp | Formulação dispersível de um agente anti-inflamatório |
US20050004098A1 (en) * | 2003-03-20 | 2005-01-06 | Britten Nancy Jean | Dispersible formulation of an anti-inflammatory agent |
US20040214753A1 (en) * | 2003-03-20 | 2004-10-28 | Britten Nancy Jean | Dispersible pharmaceutical composition for treatment of mastitis and otic disorders |
US20050009931A1 (en) * | 2003-03-20 | 2005-01-13 | Britten Nancy Jean | Dispersible pharmaceutical composition for treatment of mastitis and otic disorders |
US7105467B2 (en) * | 2003-07-08 | 2006-09-12 | Pharmacore, Inc. | Nickel catalyzed cross-coupling reactions between organomagnesium compounds and anisole derivatives |
US7105707B2 (en) * | 2003-12-17 | 2006-09-12 | Pharmacore, Inc. | Process for preparing alkynyl-substituted aromatic and heterocyclic compounds |
US20060035893A1 (en) | 2004-08-07 | 2006-02-16 | Boehringer Ingelheim International Gmbh | Pharmaceutical compositions for treatment of respiratory and gastrointestinal disorders |
US20080119498A1 (en) * | 2004-12-06 | 2008-05-22 | Masatomo Kato | Therapeutic Agent for Pruritus Comprising P38 Map Kinase Inhibitor as the Active Ingredient |
PE20060777A1 (es) | 2004-12-24 | 2006-10-06 | Boehringer Ingelheim Int | Derivados de indolinona para el tratamiento o la prevencion de enfermedades fibroticas |
JP2007145819A (ja) * | 2005-10-28 | 2007-06-14 | Tanabe Seiyaku Co Ltd | 医薬組成物 |
WO2007056016A2 (en) * | 2005-11-02 | 2007-05-18 | Kemia, Inc. | Bisamide cytokine inhibitors |
EP1992344A1 (en) | 2007-05-18 | 2008-11-19 | Institut Curie | P38 alpha as a therapeutic target in pathologies linked to FGFR3 mutation |
EP2111861A1 (en) | 2008-04-21 | 2009-10-28 | Ranbaxy Laboratories Limited | Compositions of phosphodiesterase type IV inhibitors |
ES2917222T3 (es) | 2011-12-28 | 2022-07-07 | Kyoto Prefectural Public Univ Corp | Normalización del cultivo de células endoteliales de la córnea |
WO2015072580A1 (ja) | 2013-11-14 | 2015-05-21 | 学校法人同志社 | 細胞増殖促進または細胞障害抑制による角膜内皮治療薬 |
US10342786B2 (en) | 2017-10-05 | 2019-07-09 | Fulcrum Therapeutics, Inc. | P38 kinase inhibitors reduce DUX4 and downstream gene expression for the treatment of FSHD |
PT3691620T (pt) | 2017-10-05 | 2022-10-06 | Fulcrum Therapeutics Inc | Os inibidores da quinase p38 reduzem a expressão de dux4 e genes a jusante para o tratamento de fshd |
IL305573A (en) | 2021-03-15 | 2023-10-01 | Saul Yedgar | Hyaluronic acid conjugated with dipalmitoyl phosphatidyl ethanolamine in combination with non-steroidal anti-inflammatory drugs (NSAIDs) for the treatment or suppression of inflammatory diseases |
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US2748119A (en) | 1954-06-23 | 1956-05-29 | Searle & Co | 6-furyl and 6-thienyl derivatives of 4-trifluoromethyl-2-pyrimidinamines |
US3557114A (en) | 1968-12-23 | 1971-01-19 | Merck & Co Inc | 1-substituted-3-(2-pyrimidinyl) imidazolium salts |
US3707475A (en) | 1970-11-16 | 1972-12-26 | Pfizer | Antiinflammatory imidazoles |
US3929807A (en) | 1971-05-10 | 1975-12-30 | Ciba Geigy Corp | 2-Substituted-4(5)-(aryl)-5(4)-(2,3 or -4-pyridyl)-imidazoles |
US3940486A (en) | 1971-05-10 | 1976-02-24 | Ciba-Geigy Corporation | Imidazole derivatives in the treatment of pain |
US4058614A (en) | 1973-12-04 | 1977-11-15 | Merck & Co., Inc. | Substituted imidazole compounds and therapeutic compositions therewith |
US4199592A (en) | 1978-08-29 | 1980-04-22 | E. I. Du Pont De Nemours And Company | Antiinflammatory 4,5-diaryl-2-nitroimidazoles |
CA1175431A (en) | 1980-07-25 | 1984-10-02 | Alfred Sallmann | Tri-substituted imidazole derivatives, processes for their manufacture, pharmaceutical preparations containing them, and their use |
US4503065A (en) | 1982-08-03 | 1985-03-05 | E. I. Du Pont De Nemours And Company | Antiinflammatory 4,5-diaryl 1-2-halo imidazoles |
US4565875A (en) | 1984-06-27 | 1986-01-21 | Fmc Corporation | Imidazole plant growth regulators |
US4686231A (en) | 1985-12-12 | 1987-08-11 | Smithkline Beckman Corporation | Inhibition of 5-lipoxygenase products |
IL83467A0 (en) | 1986-08-15 | 1988-01-31 | Fujisawa Pharmaceutical Co | Imidazole derivatives,processes for their preparation and pharmaceutical compositions containing the same |
CA2098177A1 (en) | 1990-12-13 | 1992-06-13 | Jerry L. Adams | Csaids |
AU9169991A (en) | 1990-12-13 | 1992-07-08 | Smithkline Beecham Corporation | Novel csaids |
US5656644A (en) | 1994-07-20 | 1997-08-12 | Smithkline Beecham Corporation | Pyridyl imidazoles |
IL104369A0 (en) * | 1992-01-13 | 1993-05-13 | Smithkline Beecham Corp | Novel compounds and compositions |
US5593992A (en) * | 1993-07-16 | 1997-01-14 | Smithkline Beecham Corporation | Compounds |
IL110296A (en) | 1993-07-16 | 1999-12-31 | Smithkline Beecham Corp | Imidazole compounds process for their preparation and pharmaceutical compositions containing them |
US5593991A (en) * | 1993-07-16 | 1997-01-14 | Adams; Jerry L. | Imidazole compounds, use and process of making |
US5670527A (en) * | 1993-07-16 | 1997-09-23 | Smithkline Beecham Corporation | Pyridyl imidazole compounds and compositions |
ZA945363B (en) * | 1993-07-21 | 1995-03-14 | Smithkline Beecham Corp | Novel compounds |
PT672041E (pt) | 1993-10-01 | 2002-04-29 | Novartis Ag | Derivados da piridina farmacologicamente activos e processos para a sua preparacao |
US5543520A (en) | 1993-10-01 | 1996-08-06 | Ciba-Geigy Corporation | Pyrimidine derivatives |
ATE325113T1 (de) | 1993-10-01 | 2006-06-15 | Novartis Pharma Gmbh | Pharmacologisch wirksame pyrimidinderivate und verfahren zu deren herstellung |
US5612340A (en) | 1993-10-01 | 1997-03-18 | Ciba-Geigy Corporation | Pyrimidineamine derivatives and processes for the preparation thereof |
EP0802908A4 (en) * | 1995-01-12 | 2001-04-11 | Smithkline Beecham Corp | NEW COMPOUNDS |
US5658903A (en) * | 1995-06-07 | 1997-08-19 | Smithkline Beecham Corporation | Imidazole compounds, compositions and use |
US5739143A (en) * | 1995-06-07 | 1998-04-14 | Smithkline Beecham Corporation | Imidazole compounds and compositions |
AP9700912A0 (en) | 1996-01-11 | 1997-01-31 | Smithkline Beecham Corp | Novel cycloalkyl substituted imidazoles |
EP0883402A4 (en) | 1996-01-11 | 1999-08-11 | Smithkline Beecham Corp | NEW CYCLOALKYL-SUBSTITUTED IMIDAZOLES |
ATE247470T1 (de) | 1996-01-11 | 2003-09-15 | Smithkline Beecham Corp | Neue substituierte imidazolverbindungen |
ZA97175B (en) | 1996-01-11 | 1997-11-04 | Smithkline Beecham Corp | Novel substituted imidazole compounds. |
US6096739A (en) | 1996-03-25 | 2000-08-01 | Smithkline Beecham Corporation | Treatment for CNS injuries |
US6235760B1 (en) | 1996-03-25 | 2001-05-22 | Smithkline Beecham Corporation | Treatment for CNS injuries |
WO1998022109A1 (en) | 1996-11-20 | 1998-05-28 | Merck & Co., Inc. | Triaryl substituted imidazoles as glucagon antagonists |
-
1997
- 1997-01-02 AP AP9700912A patent/AP9700912A0/xx unknown
- 1997-01-08 UY UY24434A patent/UY24434A1/es unknown
- 1997-01-08 MA MA24456A patent/MA24055A1/fr unknown
- 1997-01-09 ZA ZA97173A patent/ZA97173B/xx unknown
- 1997-01-10 CN CN97192881A patent/CN1213305A/zh active Pending
- 1997-01-10 JP JP9525466A patent/JP2000503304A/ja not_active Ceased
- 1997-01-10 IL IL12522497A patent/IL125224A0/xx unknown
- 1997-01-10 WO PCT/US1997/000619 patent/WO1997025048A1/en not_active Application Discontinuation
- 1997-01-10 CZ CZ982181A patent/CZ218198A3/cs unknown
- 1997-01-10 EP EP97905576A patent/EP0889726B1/en not_active Expired - Lifetime
- 1997-01-10 TR TR1998/01350T patent/TR199801350T2/xx unknown
- 1997-01-10 BR BR9708149A patent/BR9708149A/pt unknown
- 1997-01-10 ES ES97905576T patent/ES2229335T3/es not_active Expired - Lifetime
- 1997-01-10 HU HU9901233A patent/HUP9901233A2/hu unknown
- 1997-01-10 ID IDP970056A patent/ID18759A/id unknown
- 1997-01-10 AU AU22425/97A patent/AU715315B2/en not_active Ceased
- 1997-01-10 PL PL97327939A patent/PL327939A1/xx unknown
- 1997-01-10 US US09/101,416 patent/US6329526B1/en not_active Expired - Fee Related
- 1997-01-10 AR ARP970100105A patent/AR005434A1/es unknown
- 1997-01-10 DE DE69730704T patent/DE69730704T2/de not_active Expired - Fee Related
- 1997-01-10 NZ NZ330889A patent/NZ330889A/xx unknown
- 1997-01-10 AT AT97905576T patent/ATE276248T1/de not_active IP Right Cessation
-
1998
- 1998-07-10 MX MX9805628A patent/MX9805628A/es unknown
- 1998-07-10 NO NO983182A patent/NO983182L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
DE69730704D1 (de) | 2004-10-21 |
ES2229335T3 (es) | 2005-04-16 |
MA24055A1 (fr) | 1997-10-01 |
JP2000503304A (ja) | 2000-03-21 |
ZA97173B (en) | 1997-07-18 |
IL125224A0 (en) | 1999-03-12 |
DE69730704T2 (de) | 2005-09-22 |
MX9805628A (es) | 1998-11-29 |
EP0889726A1 (en) | 1999-01-13 |
AP9700912A0 (en) | 1997-01-31 |
US6329526B1 (en) | 2001-12-11 |
EP0889726A4 (en) | 1999-07-21 |
WO1997025048A1 (en) | 1997-07-17 |
NZ330889A (en) | 2000-03-27 |
HUP9901233A2 (hu) | 2000-04-28 |
AU715315B2 (en) | 2000-01-20 |
ATE276248T1 (de) | 2004-10-15 |
BR9708149A (pt) | 1999-07-27 |
PL327939A1 (en) | 1999-01-04 |
ID18759A (id) | 1998-05-07 |
TR199801350T2 (xx) | 1998-10-21 |
CN1213305A (zh) | 1999-04-07 |
NO983182L (no) | 1998-09-09 |
AR005434A1 (es) | 1999-06-23 |
EP0889726B1 (en) | 2004-09-15 |
CZ218198A3 (cs) | 1999-09-15 |
AU2242597A (en) | 1997-08-01 |
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