USB313531I5 - - Google Patents

Info

Publication number
USB313531I5
USB313531I5 US31353172A USB313531I5 US B313531 I5 USB313531 I5 US B313531I5 US 31353172 A US31353172 A US 31353172A US B313531 I5 USB313531 I5 US B313531I5
Authority
US
United States
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
Other languages
English (en)
Inventor
H Ott
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz AG
Original Assignee
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz AG filed Critical Sandoz AG
Priority to US313531A priority Critical patent/US3925548A/en
Publication of USB313531I5 publication Critical patent/USB313531I5/en
Application granted granted Critical
Publication of US3925548A publication Critical patent/US3925548A/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/06—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals
    • C07D295/073—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals with the ring nitrogen atoms and the substituents separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
US313531A 1968-11-12 1972-12-08 1-Substituted-4-aryl-2(1H)-quinazolinones as pharmaceutical agents Expired - Lifetime US3925548A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
US313531A US3925548A (en) 1968-11-12 1972-12-08 1-Substituted-4-aryl-2(1H)-quinazolinones as pharmaceutical agents

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US00775201A US3723432A (en) 1968-11-12 1968-11-12 1-substituted-4-aryl-2(1h)-quinazolinones and their preparation
US313531A US3925548A (en) 1968-11-12 1972-12-08 1-Substituted-4-aryl-2(1H)-quinazolinones as pharmaceutical agents

Publications (2)

Publication Number Publication Date
USB313531I5 true USB313531I5 (en)) 1975-01-28
US3925548A US3925548A (en) 1975-12-09

Family

ID=25103642

Family Applications (2)

Application Number Title Priority Date Filing Date
US00775201A Expired - Lifetime US3723432A (en) 1967-10-04 1968-11-12 1-substituted-4-aryl-2(1h)-quinazolinones and their preparation
US313531A Expired - Lifetime US3925548A (en) 1968-11-12 1972-12-08 1-Substituted-4-aryl-2(1H)-quinazolinones as pharmaceutical agents

Family Applications Before (1)

Application Number Title Priority Date Filing Date
US00775201A Expired - Lifetime US3723432A (en) 1967-10-04 1968-11-12 1-substituted-4-aryl-2(1h)-quinazolinones and their preparation

Country Status (19)

Country Link
US (2) US3723432A (en))
AT (4) AT310169B (en))
BE (1) BE741529A (en))
BG (10) BG16042A3 (en))
BR (1) BR6914095D0 (en))
CH (1) CH521972A (en))
DE (1) DE1956384C3 (en))
DK (1) DK129347B (en))
ES (1) ES373377A1 (en))
FR (1) FR2024830B1 (en))
GB (1) GB1282612A (en))
IE (1) IE33933B1 (en))
IL (1) IL33348A (en))
NL (1) NL6916514A (en))
NO (1) NO124032B (en))
OA (1) OA03829A (en))
PL (1) PL72695B1 (en))
SE (2) SE376917B (en))
ZA (1) ZA697910B (en))

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3923803A (en) * 1968-07-18 1975-12-02 Sumitomo Chemical Co 2(1H)-Quinozalinones and process therefor
US3642791A (en) * 1969-08-13 1972-02-15 Sandoz Ag Morpholino-1-substituted-2(1h)-quinazolinones
US4208343A (en) * 1970-10-30 1980-06-17 Westinghouse Electric Corp. 2,4 Diamino benzonitrile
BE785937A (fr) * 1971-07-08 1973-01-08 Sandoz Sa Nouveaux derives de la quinazoline, leur preparation et leur application comme medicaments
US3937705A (en) * 1972-03-09 1976-02-10 Sandoz, Inc. 1-isopropyl-7-methyl-4-(p-fluorophenyl)-2(1h)-quinazolinone
US4064246A (en) * 1976-10-12 1977-12-20 Sandoz, Inc. Hydroxymethyl-substituted-2(1H)-quinazolinones
US4071516A (en) * 1976-08-20 1978-01-31 Sandoz, Inc. 4-(Acyloxyphenyl)-quinazolin-2(1H)-ones
US4160092A (en) * 1977-06-16 1979-07-03 E. I. Du Pont De Nemours And Company Quinazolinone oxides and their use as intermediates for pharmaceutical agents
US4224328A (en) * 1979-04-11 1980-09-23 Sandoz, Inc. Methods with 1-substituted-4-aryl-quinazolin-2(1H)-ones and thiones and pyrido[2,3-d]pyrimidin-2-ones as platelet aggregation inhibitors
CH645362A5 (de) * 1979-07-05 1984-09-28 Sandoz Ag Verfahren zur herstellung von 4-phenyl-2(1h)-chinazolinonen.
FR2676042B1 (fr) * 1991-05-02 1993-07-23 Commissariat Energie Atomique Procede de preparation d'un borohydrure de metal alcalin tel que le borohydrure de lithium.
US7230000B1 (en) * 1999-10-27 2007-06-12 Cytokinetics, Incorporated Methods and compositions utilizing quinazolinones
US6545004B1 (en) 1999-10-27 2003-04-08 Cytokinetics, Inc. Methods and compositions utilizing quinazolinones
AR038658A1 (es) * 2001-06-15 2005-01-26 Novartis Ag Derivados de 4-aril-2(1h) quinazolinona y 4-aril-quinazolina 2-sustituidas, un proceso para su preparacion, composiciones farmaceuticas y el uso de dichos derivados para la preparacion de un medicamento
AU2002346471A1 (en) * 2001-11-20 2003-06-10 Cytokinetics, Inc. Process for the racemization of chiral quinazolinones
US7009049B2 (en) * 2002-02-15 2006-03-07 Cytokinetics, Inc. Syntheses of quinazolinones
AU2003270015A1 (en) 2002-05-09 2003-12-02 Cytokinetics, Inc. Compounds, compositions, and methods
EP1503993A4 (en) * 2002-05-09 2006-05-03 Cytokinetics Inc COMPOUNDS, METHODS AND COMPOSITIONS
JP2005536475A (ja) * 2002-05-23 2005-12-02 サイトキネティクス・インコーポレーテッド 化合物、組成物、および方法
AU2003236527A1 (en) * 2002-06-14 2003-12-31 Cytokinetics, Inc. Compounds, compositions, and methods
WO2004009036A2 (en) * 2002-07-23 2004-01-29 Cytokinetics, Inc. Compounds compositions and methods
WO2004018058A2 (en) * 2002-08-21 2004-03-04 Cytokinetics, Inc. Compounds, compositions, and methods
AU2003277079A1 (en) * 2002-09-30 2004-05-04 Cytokinetics, Inc. Compounds, compositions, and methods
GB0230015D0 (en) * 2002-12-23 2003-01-29 Novartis Ag Organic compounds
US8410102B2 (en) 2003-05-27 2013-04-02 Galderma Laboratories Inc. Methods and compositions for treating or preventing erythema
US7439241B2 (en) * 2003-05-27 2008-10-21 Galderma Laboratories, Inc. Compounds, formulations, and methods for treating or preventing rosacea
JP2007510652A (ja) * 2003-11-03 2007-04-26 サイトキネティクス・インコーポレーテッド ピリミジン−４−オン化合物、組成物、および方法
EP1680420A4 (en) * 2003-11-07 2008-09-24 Cytokinetics Inc COMPOUNDS, COMPOSITIONS AND METHODS
WO2005061460A1 (en) * 2003-12-08 2005-07-07 Cytokinetics, Inc. Compounds, compositions, and methods
CN101801937A (zh) * 2007-06-22 2010-08-11 艾科尔公司 喹唑啉酮化合物及其使用方法
US8058469B2 (en) * 2008-11-03 2011-11-15 Sabic Innovative Plastics Ip B.V. Method for making carbamates, ureas and isocyanates
EP2329849B1 (en) 2009-11-18 2015-04-29 Galderma Research & Development Combination of alpha-2 adrenergic receptor agonist and non-steroidal anti-inflammatory agent for treating or preventing an inflammatory skin disorder
US8394800B2 (en) 2009-11-19 2013-03-12 Galderma Laboratories, L.P. Method for treating psoriasis
US20130071489A1 (en) 2010-03-26 2013-03-21 Galderma Research & Development Snc Methods and compositions for safe and effective treatment of erythema
KR20150058551A (ko) 2010-03-26 2015-05-28 갈데르마 리써어치 앤드 디벨로프먼트 모세혈관 확장증의 안전하고 유효한 치료를 위한 개선된 방법 및 조성물
US8053427B1 (en) 2010-10-21 2011-11-08 Galderma R&D SNC Brimonidine gel composition
MX354697B (es) 2010-10-21 2018-03-15 Galderma Sa Composiciones de gel de brimonidina y métodos de uso.

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3452041A (en) * 1965-05-19 1969-06-24 American Home Prod Hydantoin compounds and methods of preparation

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3452041A (en) * 1965-05-19 1969-06-24 American Home Prod Hydantoin compounds and methods of preparation

Also Published As

Publication number Publication date
CH521972A (de) 1972-04-30
BG16037A3 (bg) 1972-05-20
SE376917B (en)) 1975-06-16
GB1282612A (en) 1972-07-19
AT319949B (de) 1975-01-10
BG16043A3 (bg) 1972-05-20
BG15573A3 (bg) 1976-06-26
AT319950B (de) 1975-01-10
FR2024830B1 (en)) 1973-07-13
NO124032B (en)) 1972-02-21
PL72695B1 (en) 1974-08-30
BG16038A3 (bg) 1972-05-20
US3925548A (en) 1975-12-09
OA03829A (fr) 1971-12-24
SE374920B (en)) 1975-03-24
BG16036A3 (bg) 1972-05-20
ES373377A1 (es) 1972-05-16
BR6914095D0 (pt) 1973-02-13
DE1956384A1 (de) 1970-06-11
DK129347B (da) 1974-09-30
AT310169B (de) 1973-09-25
BG16042A3 (bg) 1972-05-20
IL33348A (en) 1973-04-30
BG16041A3 (bg) 1972-05-20
IE33933L (en) 1970-05-12
NL6916514A (en)) 1970-05-14
DE1956384C3 (de) 1980-10-09
DK129347C (en)) 1975-02-17
DE1956384B2 (de) 1980-02-07
IL33348A0 (en) 1970-01-29
BE741529A (en)) 1970-05-11
AT310176B (de) 1973-09-25
SU366612A3 (en)) 1973-01-16
IE33933B1 (en) 1974-12-11
BG16039A3 (bg) 1972-05-20
BG16040A3 (bg) 1972-05-20
US3723432A (en) 1973-03-27
ZA697910B (en) 1971-07-28
FR2024830A1 (en)) 1970-09-04
BG16188A3 (bg) 1972-07-20

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