US20130023819A1 - System and method for monitoring at least one blood parameter - Google Patents

System and method for monitoring at least one blood parameter Download PDF

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Publication number
US20130023819A1
US20130023819A1 US13/521,713 US201113521713A US2013023819A1 US 20130023819 A1 US20130023819 A1 US 20130023819A1 US 201113521713 A US201113521713 A US 201113521713A US 2013023819 A1 US2013023819 A1 US 2013023819A1
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Prior art keywords
blood
values
data
medicament
patient
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US13/521,713
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English (en)
Inventor
Hans-Otto Maier
Torsten Doenhoff
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B Braun Melsungen AG
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B Braun Melsungen AG
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Assigned to B. BRAUN MELSUNGEN AG reassignment B. BRAUN MELSUNGEN AG ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: DOENHOFF, TORSTEN, MAIER, HANS-OTTO
Publication of US20130023819A1 publication Critical patent/US20130023819A1/en
Abandoned legal-status Critical Current

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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/168—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
    • A61M5/172—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body electrical or electronic
    • A61M5/1723—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body electrical or electronic using feedback of body parameters, e.g. blood-sugar, pressure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/157—Devices characterised by integrated means for measuring characteristics of blood
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2562/00—Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
    • A61B2562/08—Sensors provided with means for identification, e.g. barcodes or memory chips
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150206—Construction or design features not otherwise provided for; manufacturing or production; packages; sterilisation of piercing element, piercing device or sampling device
    • A61B5/150229—Pumps for assisting the blood sampling
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150206—Construction or design features not otherwise provided for; manufacturing or production; packages; sterilisation of piercing element, piercing device or sampling device
    • A61B5/150236—Pistons, i.e. cylindrical bodies that sit inside the syringe barrel, typically with an air tight seal, and slide in the barrel to create a vacuum or to expel blood
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150206—Construction or design features not otherwise provided for; manufacturing or production; packages; sterilisation of piercing element, piercing device or sampling device
    • A61B5/150244—Rods for actuating or driving the piston, i.e. the cylindrical body that sits inside the syringe barrel, typically with an air tight seal, and slides in the barrel to create a vacuum or to expel blood
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150374—Details of piercing elements or protective means for preventing accidental injuries by such piercing elements
    • A61B5/150381—Design of piercing elements
    • A61B5/150389—Hollow piercing elements, e.g. canulas, needles, for piercing the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150374—Details of piercing elements or protective means for preventing accidental injuries by such piercing elements
    • A61B5/150381—Design of piercing elements
    • A61B5/150503—Single-ended needles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150763—Details with identification means
    • A61B5/150786—Optical identification systems, e.g. bar codes, colour codes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/155—Devices specially adapted for continuous or multiple sampling, e.g. at predetermined intervals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/48—Other medical applications
    • A61B5/4836—Diagnosis combined with treatment in closed-loop systems or methods
    • A61B5/4839—Diagnosis combined with treatment in closed-loop systems or methods combined with drug delivery
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M2005/14208—Pressure infusion, e.g. using pumps with a programmable infusion control system, characterised by the infusion program
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/60—General characteristics of the apparatus with identification means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/60—General characteristics of the apparatus with identification means
    • A61M2205/6009—General characteristics of the apparatus with identification means for matching patient with his treatment, e.g. to improve transfusion security
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2230/00—Measuring parameters of the user
    • A61M2230/20—Blood composition characteristics
    • A61M2230/201—Glucose concentration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M5/14244—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00584—Control arrangements for automatic analysers
    • G01N35/00722—Communications; Identification
    • G01N35/00871—Communications between instruments or with remote terminals
    • G01N2035/00881—Communications between instruments or with remote terminals network configurations
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/28—Electrolytic cell components
    • G01N27/30—Electrodes, e.g. test electrodes; Half-cells
    • G01N27/327—Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
    • G01N27/3271—Amperometric enzyme electrodes for analytes in body fluids, e.g. glucose in blood
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H20/00—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance
    • G16H20/10—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients
    • G16H20/17—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients delivered via infusion or injection

Definitions

  • the invention concerns a system and a method for monitoring at least one blood parameter of the blood of a prespecified patient, with an access device to create an access to the patient's blood, an extraction device to extract a quantity of blood to obtain a blood sample, a blood analysis device to analyse the blood sample, a calculation device to calculate medicament parameters of a medicament to be administered to the patient, and a supply device to supply the medicament with the calculated medicament parameters, according to the preamble of claim 1 and the preamble of claim 9 .
  • Systems for extracting blood and monitoring at least one blood parameter of the blood of a prespecified patient are well known in various forms. For example there are systems which monitor the glucose value of the blood as a relevant blood parameter in order, after calculation of an insulin value, to supply to the patient as a medicament a corresponding quantity of insulin in response to the glucose value determined.
  • the supply device can be an insulin supply device or an infusion pump which maintains the insulin value present in the patient's blood circulation at a prespecifiable level in response to a previously measured blood glucose value in the patient's blood circulation.
  • supply devices for at least one nutrient of nutrition supplied to the blood circulation directly or indirectly via at least one nutrition supply device can be administered to the patient.
  • All such supply devices when integrated into a system for administering medicaments and/or nutrients, have previously required the input of values by a doctor or further clinical personnel to form the basis for the supply by means of the supply device.
  • quantity values, time intervals at which the supply should be made, intermittent supply etc. are entered as the basis for subsequent supply of for example insulin.
  • This supply is preceded by the manual taking of a blood sample from the patient, which requires the intervention of clinical personnel. Also further clinical personnel is required with the necessary professional knowledge of the input function of the supply device, such as the infusion pump, in order to subsequently perform the supply.
  • Such an extraction of blood by the clinical personnel has the disadvantage that blood samples taken can be confused. This means that wrong blood samples can be allocated to the patient, wherein it must be taken into account that blood analysis devices are frequently used in common for a large number of blood samples from widely varying patients.
  • the invention is based on the object of providing a system and a method for monitoring at least one blood parameter of the blood of a prespecified patient, which has a high degree of automation and avoids the errors caused by clinical personnel.
  • the core concept of the invention is that in a system for monitoring at least one blood parameter of the blood of a prespecified patient with the following devices:
  • an access device to create an access to the patient's blood through the skin
  • an extraction device for extracting a blood quantity to obtain a blood sample
  • a blood analysis device that can be used for a multiplicity of blood samples from various patients to analyse the blood sample with regard to prespecifiable blood parameters
  • a first calculation device for calculating medicament parameters of a medicament to be administered to the patient on the basis of the parameters determined from the blood analysed
  • a supply device to supply the medicament with the calculated medicament parameters
  • an allocation is made directly after extraction of the blood quantity and before its supply to the blood analysis device, namely between the blood sample and at least one identification element with personal and treatment-related data in order to perform an automatic identification.
  • an identification element generating device which has the function of generating the identification element, which can for example be a barcode or data matrix code in two-dimensional or three-dimensional form, or is a transponder, in order to then allocate this to the extraction device.
  • data which are also patient-related or personal and also treatment-related data can be entered in the blood analysis device by means of a determination or calculation device such as for example a PC with an input keyboard or a PC with connected read device for a barcode scanner, and compared with the data from the identification element which is for example a barcode and is read by means of the blood analysis device.
  • a determination or calculation device such as for example a PC with an input keyboard or a PC with connected read device for a barcode scanner
  • Such comparison allows the avoidance of errors in allocation of the blood to be analysed to the respective patient, since subsequent blood analysis takes place only when the comparison unit and the allocation unit give a release signal to the analysis unit. This occurs only when the comparison unit establishes correlating data.
  • Such a determination or reading of personal and treatment-related data can take place by means of a barcode scanner which scans the armband of a patient bearing such a barcode, and reads the barcode.
  • the barcode read is then printed out by means of a printer or the identification element generating device and applied to the syringe or other container.
  • This is applied preferably to the blood-receiving container of the syringe on the outside by means of an adhesive surface or to a connected blood-receiving container.
  • the barcode read is converted by means of a second calculation device into personal and treatment-related data and correspondingly determined, in order then for this data to be passed on to the blood analysis device for comparison purposes.
  • the data entered in the second calculation device are the scanned data of a further identification element or the data entered via a keyboard on the person and treatment of the patient.
  • the personal and treatment-related data on the identification element are encrypted.
  • the data can be information on a prespecifiable time of the blood extraction to be performed, the name of the patient and the medicament, the medicament dose to be administered, and similar data.
  • the blood parameters to be determined of the blood to be analysed can contain glucose values, pH values, coagulation factors of the blood and further blood gas data such as for example CO 2 values, PO 2 values, potassium values, bicarbonate values, basic deviation values and similar.
  • Further data which can be contained on or in the identification feature which is applied to the blood sample or applied to the syringe can be information on the time of blood extraction, the date of blood extraction, the summer or winter time, or similar. Also data on the type of blood can be included in the identification element of the blood sample. As a result comprehensively all data can be passed on to the blood analysis device, wherein data such as information on the time, date and summer or winter time can also be generated by means of the second calculation device on input of the personal and treatment-related data and passed on to the blood analysis device.
  • the blood analysis device is connected with the first calculation device and this is connected with the supply device for the supply of medicament such that a data transfer can take place.
  • This can be both hard-wired and wireless.
  • the various devices can be arranged at different places and a high degree of automation is achieved in the automated administration of medicaments, even to patients in the intensive treatment unit, on the basis of measurement values and patient-induced parameters.
  • the blood parameter to be determined can be glucose and the medicament to be administered can be insulin and the supply device can be an insulin pump:
  • the blood sample is allocated by means of an identification element generating device to at least one identification element with personal and treatment-related data in order to obtain automatic identification.
  • the method also comprises the reading of personal and treatment-related data of the identification element by means of a read unit which is preferably connected with the blood analysis device or arranged within this, and the allocation by means of an allocation unit of the data read to the blood to be analysed within the blood analysis device.
  • FIG. 1 in a diagrammatic depiction, the system and its function in one embodiment of the invention
  • FIGS. 2 a and 2 b a flow diagram which illustrates the method according to one embodiment of the invention.
  • FIG. 1 in a diagrammatic depiction shows the system according to the invention according to one embodiment of the invention. This depiction shows that a needle 2 penetrates through the skin of a patient 1 , of whom a hand and arm are shown, as an access device in order to extract blood.
  • the blood extraction takes place in the normal known manner, for example by means of a syringe 3 as an extraction device.
  • an armband 4 is scanned on which a barcode is shown.
  • This barcode contains personal and treatment-related data of the patient wearing this armband. For example these can be the patient's name, the name of the medicament to be administered, the age and further personal data.
  • the read device 6 After scanning of the barcode on the armband 4 , the read device 6 sends a corresponding barcode signal to a calculation device 7 whose task is to determine, from the read barcode, the relevant personal and treatment-specific data—which includes the time of blood extraction—and pass on these data to an identification element generating device 9 which can be a barcode printer.
  • This printer 9 prints a barcode with the personal and treatment-specific data and the barcode is affixed, for example in the form of a barcode label 10 , onto the blood sample receiving container of the syringe 3 .
  • the calculation device 7 sends the personal and treatment-specific data determined to a comparison unit 15 within a blood analysis device 12 .
  • personal and treatment-specific data can be entered in the calculation device 7 in order to be included in the barcode to be printed or taken into account in the comparison unit 15 .
  • the blood present in the syringe 3 is collected by the blood analysis device 12 for analysis purposes.
  • the barcode 10 is scanned by a further barcode scanner 13 which is connected with a read unit 14 within the blood analysis device 12 .
  • the barcode data read are again converted into personal and treatment-specific electronic data and passed on to the comparison unit 15 .
  • the comparison unit 15 the data which have been read by the barcode scanner 13 from the barcode 10 are now compared with the data provided by the calculation device 7 . As soon as correlations in the data are found on such a comparison, these personal and treatment-related data are allocated to the blood sample 3 . This is carried out by an allocation unit 16 .
  • an analysis unit 17 After allocation by the allocation unit 16 , within an analysis unit 17 the actual analysis of the blood to be analysed takes place and then one or more desired blood parameter values are established.
  • the glucose value within the blood taken can be found, in order to subsequently administer as a medicament insulin at the desired level corresponding to the medicament parameters.
  • the data which reflect the analysis measurement values and for example contain the amount of a glucose value are passed on to a calculation device 18 whose purpose is to determine, by means of an internal database and corresponding memory unit, the associated medicament with a dose corresponding to the glucose value.
  • the amount of insulin to be administered is determined by means of the calculation device 18 .
  • a supply device 19 which in this case is formed as an insulin pump.
  • This insulin pump 19 delivers insulin via a catheter 20 to the patient 1 in the desired quantity and at the desired time.
  • FIGS. 2 a and 2 b illustrate the method according to the invention according to one embodiment of the invention. It is clear from this depiction that in a step 21 a barcode is scanned on the armband of the patient by means of a barcode scanner and data are determined by means of the second calculation device 7 .
  • a barcode label is printed by means of the printer 9 .
  • the barcode label is then applied to the blood sample vessel in a step 23 .
  • the blood sample is then introduced in a blood analysis device in a step 24 , whereupon the barcode label is read by a barcode scanner of the blood analysis device in a step 25 .
  • step 26 After the data of the barcode label and the data determined are compared in the comparison unit 15 according to step 26 , it is established in a query 27 whether these are identical. If this is not the case, according to step 28 no analysis is possible and the process is terminated.
  • a step 29 and a step 30 the data are allocated to the blood sample to be analysed and the blood sample is analysed.
  • this calculation device calculates the medicament parameters. These are for example the amount and duration of administration of the medicament insulin.
  • a signal is sent to the pump 19 , which in a step 34 administers the medicament to the patient in the desired quantity and at the desired time interval.

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
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  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
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  • Physics & Mathematics (AREA)
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  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Electrochemistry (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • External Artificial Organs (AREA)
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  • Medical Preparation Storing Or Oral Administration Devices (AREA)
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US13/521,713 2010-03-05 2011-03-03 System and method for monitoring at least one blood parameter Abandoned US20130023819A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
DE102010010567 2010-03-05
DE102010010567.8 2010-03-05
DE102010012733.7 2010-03-24
DE102010012733 2010-03-24
PCT/EP2011/053248 WO2011107571A1 (de) 2010-03-05 2011-03-03 System und verfahren zur überwachung von mindestens einem blutparameter

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US20130023819A1 true US20130023819A1 (en) 2013-01-24

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ID=43920342

Family Applications (6)

Application Number Title Priority Date Filing Date
US13/577,017 Abandoned US20130023851A1 (en) 2010-03-05 2011-03-03 System and method for administering medicaments to a patient
US13/578,799 Abandoned US20120323215A1 (en) 2010-03-05 2011-03-03 System and method for administering medicaments on the basis of urine values
US13/581,225 Abandoned US20120323141A1 (en) 2010-03-05 2011-03-03 System for determining treatment-related data for the administration of drugs to patients to be treated taking into account important individual factors
US13/521,713 Abandoned US20130023819A1 (en) 2010-03-05 2011-03-03 System and method for monitoring at least one blood parameter
US13/575,857 Abandoned US20120316465A1 (en) 2010-03-05 2011-03-03 System and method for monitoring the time period for blood parameter monitoring processes
US13/579,858 Active 2033-11-09 US9861745B2 (en) 2010-03-05 2011-03-03 System and method for monitoring time intervals during blood parameter monitoring

Family Applications Before (3)

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US13/577,017 Abandoned US20130023851A1 (en) 2010-03-05 2011-03-03 System and method for administering medicaments to a patient
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