US20130001117A1 - Tray for Handling Syringe Barrels - Google Patents

Tray for Handling Syringe Barrels Download PDF

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Publication number
US20130001117A1
US20130001117A1 US13/634,074 US201113634074A US2013001117A1 US 20130001117 A1 US20130001117 A1 US 20130001117A1 US 201113634074 A US201113634074 A US 201113634074A US 2013001117 A1 US2013001117 A1 US 2013001117A1
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United States
Prior art keywords
syringe barrel
combination
tray
syringe
barrel
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
US13/634,074
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English (en)
Inventor
Barry Peter Liversidge
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Individual
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Individual
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Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of US20130001117A1 publication Critical patent/US20130001117A1/en
Priority to US14/141,183 priority Critical patent/US20140102927A1/en
Priority to US14/521,992 priority patent/US9783328B2/en
Priority to US14/961,392 priority patent/US9850010B2/en
Abandoned legal-status Critical Current

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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L9/00—Supporting devices; Holding devices
    • B01L9/54—Supports specially adapted for pipettes and burettes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B5/00—Packaging individual articles in containers or receptacles, e.g. bags, sacks, boxes, cartons, cans, jars
    • B65B5/06—Packaging groups of articles, the groups being treated as single articles
    • B65B5/068—Packaging groups of articles, the groups being treated as single articles in trays
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B50/00—Containers, covers, furniture or holders specially adapted for surgical or diagnostic appliances or instruments, e.g. sterile covers
    • A61B50/20—Holders specially adapted for surgical or diagnostic appliances or instruments
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B50/00—Containers, covers, furniture or holders specially adapted for surgical or diagnostic appliances or instruments, e.g. sterile covers
    • A61B50/30—Containers specially adapted for packaging, protecting, dispensing, collecting or disposing of surgical or diagnostic appliances or instruments
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B50/00—Containers, covers, furniture or holders specially adapted for surgical or diagnostic appliances or instruments, e.g. sterile covers
    • A61B50/30—Containers specially adapted for packaging, protecting, dispensing, collecting or disposing of surgical or diagnostic appliances or instruments
    • A61B50/33—Trays
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/002—Packages specially adapted therefor, e.g. for syringes or needles, kits for diabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/008—Racks for supporting syringes or needles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D25/00—Details of other kinds or types of rigid or semi-rigid containers
    • B65D25/02—Internal fittings
    • B65D25/10—Devices to locate articles in containers
    • B65D25/108—Devices, e.g. plates, presenting apertures through which the articles project
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D25/00—Details of other kinds or types of rigid or semi-rigid containers
    • B65D25/34—Coverings or external coatings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B50/00—Containers, covers, furniture or holders specially adapted for surgical or diagnostic appliances or instruments, e.g. sterile covers
    • A61B2050/005—Containers, covers, furniture or holders specially adapted for surgical or diagnostic appliances or instruments, e.g. sterile covers with a lid or cover
    • A61B2050/0065—Peelable cover
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2207/00—Methods of manufacture, assembly or production
    • A61M2207/10—Device therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/3129—Syringe barrels
    • A61M5/3135—Syringe barrels characterised by constructional features of the proximal end
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/3202—Devices for protection of the needle before use, e.g. caps
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/02—Adapting objects or devices to another
    • B01L2200/025—Align devices or objects to ensure defined positions relative to each other
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/02—Burettes; Pipettes
    • B01L3/021—Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids
    • B01L3/0217—Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids of the plunger pump type

Definitions

  • This invention relates to the combination of a plurality of syringe barrels and a handling system therefor, suitable for use in the course of the manufacture and preparation of syringes pre-filled with a drug for subsequent injection.
  • a known step in the preparation of pre-filled syringes is the manufacture of a syringe barrel and then the loading of a plurality of those syringe barrels into a so-called tub, for storage and transport purposes to a location where the syringe barrels will be charged with a medicament and fitted with a stopper and a plunger, so permitting the subsequent performance of an injection.
  • the tub has a tray having a plurality of apertures arranged in an array and appropriately sized so that one syringe barrel is closely received in each aperture.
  • the tray is supported in the tub above the base and is a close fit therein so that by accurately positioning the tub in a handling machine, the exact centre of each syringe barrel is known, relative to the tub.
  • the syringe barrels are prepared under sterile conditions and then are mechanically loaded into a tray supported in a tub, typically with a line of the syringe barrels being picked up and deposited in free apertures in the tray. When the tray is fully loaded, the tub is sealed with a cover and often a plurality of tubs are then packed together, for storage until required for use.
  • the syringe barrels are to be loaded with a drug, under sterile conditions the syringe barrels are removed from an open tub again by a mechanical handling system which must accurately locate on each syringe barrel, by knowing the precise position of the tub and of the centres of the apertures in the tray supported within the tub.
  • a rigid or flexible needle cover to the needle before loading the syringe with a medicament.
  • a needle cover also serves to seal the sharp end of the needle and so prevent loss of medicament therethrough.
  • the needle cover is fitted to the syringe barrel before it is loaded into a tub for storage, in order to confer protection to the needle tip.
  • Such a safe needle device cannot be used with a tray where the syringe barrels closely fit in the apertures in the tray as the safe needle devices will not pass through those apertures. If the apertures are enlarged to allow the safe needle devices to pass therethrough, the syringe barrel will be located only imprecisely in the tray and so there is a high likelihood of mis-handling by a mechanical handling device for lifting the syringe barrels out of the tray.
  • a similar consideration applies in the event that a relatively large shield is to be provided on a syringe barrel to protect a pre-fitted needle, such as may occur with a relatively small diameter syringe body.
  • references to the “needle shield” as used hereinafter should be construed broadly to include such a needle hub, a safe needle device or similar component associated with a needle and having a greater diameter than an associated syringe barrel.
  • a plurality of tubular syringe barrels each having an enlargement at or adjacent one end and a needle shield mounted at the other end thereof wherein the needle shield is of a greater diameter than the syringe barrel
  • the handling system comprising a tray having an array of apertures therethrough each of a sufficient size for a syringe barrel and associated needle shield to pass therethrough and having a support surface configured for engagement by the enlargement of a syringe barrel received in the aperture when the tray is supported generally horizontally and the syringe barrel is lowered into an aperture, at least one of the part of the enlargement adjacent the syringe barrel and said support surface of an aperture having a profile configured to cause substantial concentric alignment of the enlargement within the aperture.
  • a syringe barrel located in an aperture in a tray of a handling system is accurately positioned by virtue of the interengagement of the syringe barrel enlargement with the surface of the tray around the aperture therein receiving the syringe barrel.
  • the aperture may be sufficiently large to allow a needle shield (i.e. a needle shield fitted to the syringe, a shield of a safe needle device fitted to the syringe or a needle hub) to pass therethrough in a case where the device, hub or shield has a greater diameter than that of the syringe body.
  • the enlargement of the syringe barrel may be integrally formed with the syringe barrel and so typically may comprise an outwardly projecting flange formed at the rear end of the syringe barrel, to facilitate the performance of an injection with the syringe.
  • the enlargement may be separately formed and then fitted to the syringe barrel, typically adjacent a flange provided at the rear end of the syringe barrel.
  • the profile of at least one of the enlargement and the support surface but preferably both of the enlargement and the support surface, have a reducing cross-section in the downward direction so that interengagement of a part of the enlargement with the support surface centres the syringe barrel to be coaxial with the aperture.
  • Each aperture in the tray may be provided with a tube surrounding the aperture and projecting from at least one surface (i.e. either the upper surface or the lower surface or possibly both surfaces) of the tray.
  • the tube is in the form of a hollow upstand with said support surface formed at the upper end region of the upstand.
  • the surface of the tray around the aperture or the upper end region of the upstand may have a generally conical profile of reducing cross-section in the downward direction, with the flange of the syringe barrel co-operating with that conical profile to give the required centring of the syringe body.
  • the region of the junction between the syringe barrel and the flange thereof may be formed to have a generally conical profile of reducing cross-section in the direction towards the other end of the syringe barrel—i.e. the forward end of the syringe barrel, for carrying a needle.
  • a collar may be positioned on the syringe barrel adjacent the flange, the collar being formed to have a reducing cross-section in the direction towards the other end of the syringe barrel. That reducing cross-section may be provided by a generally conical profile or by the collar having a rounded profile.
  • needle hub or needle shield used in conjunction with a syringe barrel may have a larger diameter than that of the syringe barrel, the underside of at least one of the aperture or the upper end of the upstand (if provided) may be profiled to facilitate removal of the syringe barrel carrying the device, hub or shield from the aperture.
  • the underside of the junction between the tray and the upstand may be radiused in order to guide into the upstand a needle shield of a greater diameter than the syringe barrel.
  • the support surface may be defined within the upstand by an inwardly directed rib.
  • the underside of the rib may be chamfered so as to guide the needle shield through the aperture defined by the rib within the upstand.
  • This invention extends to a combination as described above in conjunction with a cover member for a container carrying a tray and syringe barrels, the cover member being sealingly secured to the free edge of the side wall of the container, remote from the face thereof.
  • the invention further extends to a syringe barrel for use in a combination of this invention as described above and also to a tray for use in such a combination, as described above.
  • FIG. 1 is an isometric view of a tub carrying a tray of syringe barrels, with one barrel lifted from the tray, for clarity;
  • FIG. 2 shows the tub of FIG. 1 with the cover fully removed, the tray of syringe barrels raised from the tub, and one barrel lifted from the tray;
  • FIG. 3 is a detail view on an enlarged scale of the encircled part marked A on FIG. 2 ;
  • FIG. 4 is a part view on the corner region of the tray of FIGS. 1 to 3 but showing the first embodiment of this invention
  • FIG. 5 is a detail view on an enlarged scale of the encircled part marked E on FIG. 4 ;
  • FIG. 6 shows the first embodiment of a syringe barrel locating in an upstand of the array of apertures in the tray
  • FIG. 7 shows the syringe barrel of FIG. 6 , when fully centred
  • FIG. 8 is a cross-sectional view through the arrangement of FIG. 6 ;
  • FIG. 9 is a cross-sectional view through the fully centred arrangement of FIG. 7 ;
  • FIGS. 10 , 11 and 12 are cross-sectional views through second, third and fourth embodiments
  • FIG. 13 shows the embodiment of FIG. 12 when fully centred
  • FIGS. 14 and 15 respectively show a cross-section through a fifth embodiment and an isometric view of the syringe barrel and safety needle device of the fifth embodiment
  • FIGS. 16 and 17 correspond to FIGS. 14 and 15 but of a sixth embodiment
  • FIGS. 18 and 19 correspond to FIGS. 14 and 15 but of a seventh embodiment utilising a collar around the syringe barrel adjacent the flange thereof;
  • FIGS. 20 and 21 , FIGS. 22 and 23 and FIGS. 24 and 25 show eighth, ninth and tenth embodiments each similar to FIGS. 18 and 19 but using different forms of collar;
  • FIG. 26 shows an eleventh embodiment, similar to the first embodiment of FIGS. 6 to 9 .
  • the known system comprises a tub 10 of generally rectangular cross-sectional shape and comprising a base 11 with an upstanding side wall 12 having an out-turned lip 13 around the upper periphery of the side wall.
  • a tray 14 Disposed within the tub 10 is a tray 14 having a regular array of apertures therein, each aperture having a tubular upstand 15 surrounding the aperture and projecting upwardly from the main surface of the tray.
  • a shoulder 16 is formed around the side wall 12 to support the tray parallel to the base 11 but spaced therefrom.
  • a cover 17 is sealed to the lip 13 in order that the interior of the tub is hermetically sealed from the environment, from manufacture until such time as access is to be gained to the interior of the tub.
  • the tray includes mechanical handling recesses 18 which form no part of this invention.
  • Syringe barrels 19 of a known form are manufactured separately and are then located within the tub, for storage and transportation to a syringe filling site.
  • Each syringe barrel comprises a cylindrical part 20 having an out-turned flange 21 at the open (rear) end of the barrel.
  • the barrel merges into an integral nose having a through-bore communicating with the interior of the barrel.
  • that nose may be profiled as a connector for the hub of a needle, or a needle may be staked-in to the bore, during manufacture of the syringe barrel.
  • a needle cover conventionally is fitted over the needle on to the nose of the syringe. That needle cover may be either flexible or rigid but in either case usually is of a lesser diameter than that of the syringe barrel.
  • the syringe barrel is a close fit within an upstand 15 , such that the position of each syringe barrel relative to the tray, and hence the tub, is known. Then, by locating the tub carrying the tray on a mechanical handling system, the exact centre of each aperture in the tray and its upstand will be known, both for the insertion of syringe barrels into the tray and subsequently for removal of those syringe barrels.
  • One such mechanical handling system deposits in the tray one complete line of syringe barrels at a time and subsequently when the syringes are to be filled with medicament, another handling system simultaneously lifts a complete line of syringe barrels out of their apertures in the tray.
  • a safe needle device 22 it is advantageous to fit to the nose of a syringe barrel a safe needle device 22 , in order that protection is conferred on the needle both before an injection is performed and subsequent to an injection.
  • a safe needle device typically has a larger diameter than that of the syringe barrel with which the device is to be used. This is necessary in order that a protective shield of the safe needle device 22 may slide rearwardly over the barrel, to expose the needle.
  • a syringe manufacturer may wish to fit a relatively large diameter needle shield to a syringe barrel having a staked-in needle, especially in the case of a small syringe. The needle shield diameter may then be greater than that of the syringe barrel.
  • the apertures in the tray and the upstands surrounding the apertures of a conventional handling system as described above must be sufficiently large to allow the safe needle device 22 or a shield thereof to pass therethrough, but then a smaller diameter syringe barrel will be a relatively loose fit in the upstand and aperture of the tray, such that the exact position of the syringe barrel axis becomes indeterminate, within a defined range. Subsequent mechanical handling of the syringe barrels may be difficult with a likelihood of dropped syringe barrels on account of an inadequately precise relationship between each syringe barrel and a handling device therefor.
  • each upstand 24 has its upper end 25 (i.e. the end of the upstand remote from the tray 14 ) profiled so as to give a centring function to a syringe barrel 19 , by co-operating with the flange 21 of the barrel.
  • there are six ribs 26 equi-spaced around the upstand 24 each rib extending along the length of the upstand from the tray to the upper end 25 .
  • the upstand 24 has a generally conical internal profile 27 tapering in the downward direction and the upper end of each rib 26 has a corresponding surface disposed at the same angle as that of the profile 27 , as best seen in FIGS. 5 , 8 and 9 .
  • each upstand 24 tapers in the upward direction, with the largest diameter region in the plane of the tray 14 , as can be seen in FIGS. 8 and 9 .
  • the wall thickness of the upstand is substantially constant except for where the ribs 26 are provided, such that between the ribs, the upstand also has a conical form, with a shallow conical angle.
  • each barrel When the syringe barrels are to be removed from the tray, following transport or storage, light vibration or tapping of the tub containing the tray and syringe barrels will cause each barrel to be centred in the associated upstand and aperture, ready for removal by a mechanical handling system.
  • the conical form of each upstand facilitates entry of the larger diameter safe needle device 22 into the lower end of the upstand and so allows for minor misalignment of a barrel with the upstand.
  • the syringe barrels 19 are entirely of a known form, and require no modification as compared to a conventional syringe barrel.
  • the tub 10 is as currently employed in a known syringe handling system and it is only the tray 14 which has been modified to give the required centring functionality when the syringe barrels carry either a safe needle device or a relatively large needle shield at the forward end thereof.
  • the upstand 15 ensures that the syringe barrel is held above the surface of the tray by a sufficient distance to prevent impact between the forward end of the safe needle device or shield and the base 11 of the tub 10 .
  • each upstand 30 of the tray 14 has a relatively thick wall and both the upper and lower ends of that wall are given conical profiles 31 , 32 .
  • the conical profile 31 at the upper end of the upstand co-operates with the syringe flange 21 in the same manner as has been described above with reference to FIGS. 4 to 9 .
  • the conical profile at the lower end of the upstand facilitates entry of the safe needle device into the upstand, on removing a syringe barrel therefrom.
  • the third embodiment shown in FIG. 11 has a parallel-sided cylindrical upstand 34 provided with an in-turned lip 35 at its upper end. That lip defines a conical profile 36 tapering in the downward direction, to co-operate with the syringe flange 21 thereby to give the centring function.
  • FIGS. 12 to 17 differ from those described above, in that the syringe barrel has a modified profile in the region of the junction between the syringe barrel and the flange at the rearward end of the barrel.
  • the upstands from the tray are cylindrical as with the known handling systems but the upstands are of a sufficient diameter (greater than the diameter of the syringe barrel) to allow a safe needle device or large needle shield to pass therethrough.
  • a conical profile 38 is formed in the region of the junction between the syringe barrel 39 and the flange 40 .
  • conical profile serves to correct any axial misalignment between the syringe barrel and the upstand so that the syringe barrel is centred on the upstand.
  • a conical profile 41 at the lower end of the upstand which serves to facilitate entry of the safe needle device into the upstand on removal of a syringe barrel therefrom.
  • FIGS. 14 and 15 has the same functionality as that described above but the overall profile at the rear end 42 of the syringe barrel is modified such that there is a substantially uniform wall thickness. In all other respects, this embodiment corresponds to that of FIGS. 12 and 13 .
  • FIGS. 16 and 17 also has a substantially uniform wall thickness in the region of the junction between the syringe barrel 43 and a flange 44 at the rear end of the barrel, but the profile defined thereby has a first region 45 of generally conical form and a second region 46 of cylindrical form, of substantially the same diameter as the internal diameter of the upstand.
  • FIGS. 18 to 25 have similar functionality to that of the embodiments of FIGS. 12 to 17 but with a syringe barrel having a conventional form.
  • a collar is fitted around the syringe barrel 20 to lie closely adjacent the flange 21 , the collar having the profiles as shown.
  • the collar 48 of the embodiment of FIGS. 18 and 19 has a simple conical profile and thus corresponds to the embodiment of FIGS. 12 and 13 .
  • the embodiment of FIGS. 20 and 21 has a collar 49 of semi-circular cross-section and the part 50 thereof further from the flange 21 serves as a centring profile for the syringe barrel, in the upstand.
  • the collar 51 of the embodiment of FIGS. 22 and 23 has a first part 52 providing a conical surface, a second part 53 providing a cylindrical surface substantially equal in diameter to that of the internal diameter of the upstand and a third part similar to the first part but disposed adjacent the flange 21 .
  • the collars of FIGS. 18 to 23 may be formed of a resilient material such as silicone rubber. This resilience allows precise centring of a syringe barrel and moreover may provide a light frictional grip between a syringe barrel and an upstand.
  • the collars of FIGS. 20 to 23 are symmetrical about a central transverse plane and so may be fitted to a syringe barrel without regard to orientation, so simplifying the assembly process of a collar on a barrel.
  • the collar 55 shown in FIGS. 24 and 25 is profiled to provide a conical surface 56 giving the centring functionality in association with an upstand, as has been described above.
  • the collar also has a cylindrical surface 57 which is a close fit in the upstand, so that a syringe barrel is held centred when located as shown in FIG. 24 .
  • the collar fits around the flange 21 of the syringe barrel and this provides a radial surface 58 the width of which in the radial direction is comparable to the width of the flange 21 .
  • the provision of the collar thus does not lessen the subsequent ease of handling the syringe barrel, for example when performing an injection, as there is still access to a broad flange.
  • FIG. 26 The arrangement shown in FIG. 26 is similar to that of FIGS. 6 to 9 but differs in that an internal rib 60 extends around the inner surface of the upstand 61 , below the upper end 62 of that upstand.
  • the rib is defined by substantially conical upper and lower flank surfaces 63 , 64 , the upper flank surface 63 co-operating with the flange 21 of a syringe barrel 19 in order to give a centring function, as has been described above with reference to the previous embodiments.
  • the lower flank surface 64 serves to guide a safe needle device of shield thereof through the rib 60 , on removing the syringe barrel from the tray 65 .
  • the annular region 66 of the junction between the upstand 61 and the lower surface of the tray is radiused as shown, to facilitate the entry of the safe needle device or shield thereof into the upstand, on removing the syringe barrel from the tray.
  • the side wall of the upstand is shown extended axially beyond the rib 60 , to give a better location for the flange 21 of a syringe barrel, though it will be appreciated that the rib may be provided at the upper end of the upstand, rather than displaced downwardly by a small distance, as shown in FIG. 26 .

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US13/634,074 2010-03-12 2011-03-14 Tray for Handling Syringe Barrels Abandoned US20130001117A1 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
US14/141,183 US20140102927A1 (en) 2010-03-12 2013-12-26 Tray for Handling Syringe Barrels
US14/521,992 US9783328B2 (en) 2010-03-12 2014-10-23 Tray for handling syringe barrels
US14/961,392 US9850010B2 (en) 2010-03-12 2015-12-07 Tray for handling syringe barrels

Applications Claiming Priority (3)

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GBGB1004102.8A GB201004102D0 (en) 2010-03-12 2010-03-12 Syringe barrels and handling systems
GB1004102.8 2010-03-12
PCT/GB2011/050498 WO2011110872A1 (en) 2010-03-12 2011-03-14 Tray for handling syringe barrels

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US14/141,183 Abandoned US20140102927A1 (en) 2010-03-12 2013-12-26 Tray for Handling Syringe Barrels
US14/521,992 Active US9783328B2 (en) 2010-03-12 2014-10-23 Tray for handling syringe barrels
US14/961,392 Active 2031-06-22 US9850010B2 (en) 2010-03-12 2015-12-07 Tray for handling syringe barrels

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US14/521,992 Active US9783328B2 (en) 2010-03-12 2014-10-23 Tray for handling syringe barrels
US14/961,392 Active 2031-06-22 US9850010B2 (en) 2010-03-12 2015-12-07 Tray for handling syringe barrels

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EP (1) EP2544618B1 (es)
JP (1) JP2013521842A (es)
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GB (1) GB201004102D0 (es)
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US11419975B2 (en) * 2018-03-08 2022-08-23 Nuova Ompi S.R.L. Structure for packaging containers for pharmaceutical use
USD908916S1 (en) * 2018-06-19 2021-01-26 Tolmar Therapeutics, Inc. Syringe restrictor plate
EP4129360A4 (en) * 2020-03-31 2023-09-06 Daikyo Seiko, LTD. MEDICAL SYRINGE CYLINDER AND PACKAGING THEREOF
US11517907B1 (en) * 2021-06-28 2022-12-06 Xcaliber Sciences, Inc. Pipette tip system
US11878305B2 (en) 2021-06-28 2024-01-23 Xcaliber Sciences, Inc. Pipette tip system

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Publication number Publication date
EP2544618B1 (en) 2017-09-06
US20140102927A1 (en) 2014-04-17
US20150041349A1 (en) 2015-02-12
ES2642490T3 (es) 2017-11-16
US9850010B2 (en) 2017-12-26
JP2013521842A (ja) 2013-06-13
EP2544618A1 (en) 2013-01-16
US9783328B2 (en) 2017-10-10
HUE035361T2 (en) 2018-05-02
GB201004102D0 (en) 2010-04-28
US20160089205A1 (en) 2016-03-31
WO2011110872A1 (en) 2011-09-15

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