US20100279397A1 - Biological specimen collection and storage devices - Google Patents
Biological specimen collection and storage devices Download PDFInfo
- Publication number
- US20100279397A1 US20100279397A1 US12/278,642 US27864207A US2010279397A1 US 20100279397 A1 US20100279397 A1 US 20100279397A1 US 27864207 A US27864207 A US 27864207A US 2010279397 A1 US2010279397 A1 US 2010279397A1
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- US
- United States
- Prior art keywords
- biological sample
- container
- characteristic
- containment system
- label
- Prior art date
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Classifications
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65C—LABELLING OR TAGGING MACHINES, APPARATUS, OR PROCESSES
- B65C3/00—Labelling other than flat surfaces
- B65C3/06—Affixing labels to short rigid containers
- B65C3/08—Affixing labels to short rigid containers to container bodies
- B65C3/10—Affixing labels to short rigid containers to container bodies the container being positioned for labelling with its centre-line horizontal
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/508—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
- B01L3/5082—Test tubes per se
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/508—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/508—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
- B01L3/5082—Test tubes per se
- B01L3/50825—Closing or opening means, corks, bungs
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65C—LABELLING OR TAGGING MACHINES, APPARATUS, OR PROCESSES
- B65C9/00—Details of labelling machines or apparatus
- B65C9/46—Applying date marks, code marks, or the like, to the label during labelling
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- G—PHYSICS
- G09—EDUCATION; CRYPTOGRAPHY; DISPLAY; ADVERTISING; SEALS
- G09F—DISPLAYING; ADVERTISING; SIGNS; LABELS OR NAME-PLATES; SEALS
- G09F3/00—Labels, tag tickets, or similar identification or indication means; Seals; Postage or like stamps
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/02—Identification, exchange or storage of information
- B01L2300/021—Identification, e.g. bar codes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/02—Identification, exchange or storage of information
- B01L2300/024—Storing results with means integrated into the container
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/04—Closures and closing means
- B01L2300/046—Function or devices integrated in the closure
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/06—Auxiliary integrated devices, integrated components
- B01L2300/0627—Sensor or part of a sensor is integrated
- B01L2300/0663—Whole sensors
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/00584—Control arrangements for automatic analysers
- G01N35/00722—Communications; Identification
- G01N35/00732—Identification of carriers, materials or components in automatic analysers
- G01N2035/00861—Identification of carriers, materials or components in automatic analysers printing and sticking of identifiers
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N31/00—Investigating or analysing non-biological materials by the use of the chemical methods specified in the subgroup; Apparatus specially adapted for such methods
- G01N31/22—Investigating or analysing non-biological materials by the use of the chemical methods specified in the subgroup; Apparatus specially adapted for such methods using chemical indicators
- G01N31/229—Investigating or analysing non-biological materials by the use of the chemical methods specified in the subgroup; Apparatus specially adapted for such methods using chemical indicators for investigating time/temperature history
-
- G—PHYSICS
- G09—EDUCATION; CRYPTOGRAPHY; DISPLAY; ADVERTISING; SEALS
- G09F—DISPLAYING; ADVERTISING; SIGNS; LABELS OR NAME-PLATES; SEALS
- G09F3/00—Labels, tag tickets, or similar identification or indication means; Seals; Postage or like stamps
- G09F3/02—Forms or constructions
- G09F2003/0208—Indicia
- G09F2003/0211—Transfer or thermo-sensitive
-
- G—PHYSICS
- G09—EDUCATION; CRYPTOGRAPHY; DISPLAY; ADVERTISING; SEALS
- G09F—DISPLAYING; ADVERTISING; SIGNS; LABELS OR NAME-PLATES; SEALS
- G09F3/00—Labels, tag tickets, or similar identification or indication means; Seals; Postage or like stamps
- G09F3/02—Forms or constructions
- G09F2003/0272—Labels for containers
Definitions
- This invention relates to systems and methods for providing information relating to vessels for collecting biological fluid samples from a patient.
- Bio sample collection containers such as blood collection containers, are well-known in the medical arts. Biological sample collection containers are used to store a sample obtained by a healthcare professional from a patient until the sample is ready to be tested or used for other purposes.
- the container and/or sample are not exposed to a temperature that exceeds a certain threshold.
- it is sometimes important that the container is used within a certain timeframe upon manufacture, shipment, or some other event.
- identifying other characteristics of the sample and/or container may be useful to the healthcare practitioner. For example, identifying the integrity of the sample, whether the sample has been subjected to appropriate procedures (i.e., mixing) or whether the appropriate amount of sample has been collected may be significant.
- biological sample containers typically include a reservoir portion and a closure portion and contains some type of identifying information on the container.
- Such information is often quite limited (such as limited to container type, patient identifiers and container identifiers) and does not effectively address the issues described above in connection with container and/or sample integrity.
- Improved biological specimen containers facilitate the handling of such samples to, for instance, improve sample and container rejection criteria, increase the number and percentage of high quality samples, improve data collection and generation, monitor potential container and sample problems, and improve container and sample quality control procedures.
- a biological sample containment system and method include a container for storing the biological sample and an indicator affixed to the container for displaying at least one measured characteristics of the container or sample, wherein measurement of the characteristic is commenced by activation of the indicator.
- the biological sample containment system and method may further include a cover associated with the indicator, wherein measurement of the characteristic is commenced upon manipulation and/or removal of at least a portion of the cover and/or upon exposure to air or light.
- the characteristic that is measured may relate to the temperature to which the container is exposed, the age of the container, the amount of mixing to which the biological sample has been subjected, the time that has transpired since the biological sample has been introduced or stored by the container, the amount of time that has transpired since a user or machine performed a task related to the container, or the like.
- a biological sample containment system and method include a container for storing the biological sample and a colored scale affixed to the container, wherein the colored scale facilitates identification of at least one characteristic of the biological sample, such as the level of hemolysis associated with the biological sample.
- a biological sample containment system and method include a container for collecting a biological sample and a label affixed to the container, wherein information relating to the biological sample or container is situated on the label and at least a portion of said information is situated on a face of the label that is affixed to the container.
- the information may relate to whether the container is filled with the biological sample at a desired level.
- FIG. 1A illustrates a biological sample collection container
- FIG. 1B illustrates a biological sample collection container having a characteristic labeling system, in accordance with an embodiment of the invention
- FIG. 1C illustrates a characteristic label, in accordance with an embodiment of the invention, for use in connection with a biological sample container such as the container illustrated in FIG. 1A ;
- FIG. 2 illustrates a characteristic label, in accordance with another embodiment of the invention, for use in connection with a biological sample container such as the container illustrated in FIG. 1A ;
- FIG. 3A illustrates a biological sample collection container bearing sample and container characteristic indicators, in accordance with an embodiment of the invention.
- FIG. 3B illustrates a biological sample collection container bearing a fill range indicator, in accordance with an embodiment of the invention.
- FIG. 1A illustrates a biological sample collection container 10 .
- Container 10 includes sample collection tube 20 (such as chemistry sample tube, coagulation sample tube and hematology sample tube, etc.) and closure 16 .
- tube 20 is generally cylindrical and may be made of one or more of the following representative materials: polypropylene, polyethylene terapthalate (PET), glass, or combinations thereof.
- closure 16 may be made of a resealable elastomeric polymer and additionally may comprise a polymer cap integral to the resealable elastomeric polymer.
- container 10 may comprise a vessel of different shape (i.e., other than cylindrical) and, in some instances, may not be a tube.
- container 10 may comprise a collection cup, bag, or the like.
- collection system 10 further includes a characteristic labeling system, which in accordance with an embodiment of the invention, comprises characteristic label 90 A and label cover 80 .
- characteristic label 90 A is configured to track the amount of time that has transpired upon removal (i.e., peeling) and/or piercing (with, for example, a non-patient blood collection needle) of label cover 80 .
- Label cover 80 in accordance with an embodiment of the invention, is designed to cover and protect characteristic label 90 A.
- label cover 80 has a flap for easy gripping to facilitate removal.
- label cover 80 has an adhesive applied to the portion facing characteristic 90 A either on its entire face or a portion of such face (such as a perimeter).
- Characteristic label 90 A may, in accordance with an embodiment of the invention, use visually changing paper (“VCP”) technology that is triggered by a triggering event, such as when label cover 80 is removed or pierced.
- the triggering event causes the VCP technology to transition from an inactivated state to an activated state.
- the visually changing paper technology utilized on characteristic label 90 A may also be triggered by triggering event such as a surface modification, when for instance a label cover is applied to all or a portion of characteristic label 90 A, or alternately when all or a portion of the characteristic label 90 A has been subjected to a localized chemical environment change that commences or triggers a visual response to such change in localized chemical environment.
- An example of a localized chemical environment change may include the addition of a chemical or solution to portions of characteristic label 90 A.
- removal or piercing of label cover 80 exposes characteristic label 90 A to air which initiates a visually viewable or interpretable response correlating to time monitoring or tracking.
- adherence of a label cover 80 to characteristic label 90 A may initiate a visually viewable or interpretable response correlating to time monitoring or tracking.
- an activator matrix integral to the label cover 80 comprising, for example, an organic acid may migrate to an indicator matrix integral to characteristic label 90 a comprising, for example, an acid-base dye indicator.
- exposing characteristic label 90 A to light may initiate time monitoring.
- removal of label cover 80 may begin a chemical reaction visible to a user directly or through the use of an optical detection mechanism.
- characteristic label 90 A is configured to identify one or multiple interpretable time periods measured from the time at which a triggering event has been deliberately commenced. For instance, the following time periods and their respective time period indicators may be determined to have transpired from the triggering event such as exposure of such label upon removal of label cover 80 : a half-hour ( 92 a ), 2 hours ( 92 b ), 3 hours ( 92 c ), 6 hours ( 92 d ), 12 hours ( 92 e ), 24 hours ( 920 , 48 hours ( 92 g ), 96 hours ( 92 h ). Label 90 A may be configured to identify other time intervals further including, for example, days.
- characteristic label 90 A is exposed at time relevant to the drawing of a sample into tube 20 .
- the approximate time between drawing of the sample and a subsequent event and monitoring event (such as refrigeration, testing, etc.) may be determined or ascertained.
- label 90 A is configured such that as the number of hours transpires (from a triggering event such as time of exposure), the color of the label in the region of such time periods changes.
- label 90 A comprises a plurality of different time period indicators that respond to a shared triggering event in a manner such that different time period indicators visually correlate with their respective time intervals. Thus, the approximate time that transpires may be observed.
- a plurality of time period indicators correlate to the time transpired, preferably in a visually indicative manner.
- sample collection time By tracking the time periods described above, sample collection time, centrifugation-ready time, and sample integrity time may be measured or monitored.
- knowledge of clot time in a serum chemistry tube may be determined when, for example, the thirty minute mark is reached by label 90 A, indicating that sufficient time has transpired for the sample to clot long enough prior to centrifugation which is desired or required in certain testing protocols.
- knowledge of time that the sample has been sitting in a container prior to centrifugation may facilitate ensuring that the sample is centrifuged within the allowable period for a specific diagnostic assay, such as a period of two hours from the drawing of the sample which is desired or required in certain protocols.
- assessing whether a rack (or some other grouping or collection) of tubes meets certain time constraints is facilitated and the need to handle each individual tube may be obviated.
- label 90 A may be triggered at a time subsequent to drawing a sample into container 20 .
- label cover 80 may be lifted immediately before centrifugation or after centrifugation, so that the time of centrifugation or post-centrifugation processes may be measured.
- label 90 A may be triggered at a time subsequent to drawing a sample into container 20 by the application of a label cover 80 to all or a portion of the surface of label 90 A.
- collection system 10 further includes a characteristic labeling system, which in accordance with an embodiment of the invention, comprises characteristic label 90 a and label cover 80 .
- characteristic label 90 a is configured to track the amount of time that has transpired upon direct or indirect adherence (i.e., peeling) of characteristic label 90 a to a portion of one or both of sample collection tube 20 or closure 16 .
- Sample collection tube 20 or closure 16 may have a surface capable of transmitting an activator matrix to a portion of characteristic label 90 a , wherein characteristic label 90 a comprises an indicator matrix responsive to the activator matrix.
- Characteristic label 90 a may therefore, in accordance with an embodiment of the invention, use visually changing paper (“VCP”) technology that is triggered by a triggering event, such as when the characteristic label 90 A is adhered to one or both of sample collection tube 20 or closure 16 .
- VCP visually changing paper
- the triggering event causes the VCP technology to transition from an inactivated state to an activated state.
- characteristic label 90 b is illustrated. Similar to label 90 a , characteristic label 90 a identifies time that transpires upon exposure of such label. Characteristic 90 a , however, also includes temperature read-out 95 . In one embodiment, such read-out is effectuated by polymerization of monomers and may utilize, at least in part, the Arrhenius relationship. While read-out 95 is illustrated as a number, such read-out may be displayed in the form of a color which corresponds to a temperature range, limit, or combinations thereof.
- label 90 a monitors the maximum temperature to which the label 90 B (and therefore the container to which label 90 b is affixed) is exposed—regardless of whether the label is exposed to light or temperature.
- label 90 b is configured to measure temperature once the label is exposed to light and/or air.
- time and temperature shelf life indicator 30 As shown in FIGS. 3 a and 3 b with respect to collection tube 60 a and 60 b , one or more of the following features may be included: time and temperature shelf life indicator 30 , fill range 40 and hemolysis indicator 50 .
- Time and temperature shelf life indicator 30 may be situated on tube 60 a and may be effectuated by polymerization of monomers utilizing, at least in part, the Arrhenius relationship. With such indicator 30 , a user may easily observe whether a container has “expired” prior to drawing a sample, testing the sample, or some other point in the sample collection and testing process resulting in fewer redraws or unnecessary or inaccurate testing.
- mix indicator (not shown) may be provided on tube 20 to ensure that the appropriate number of mixes and amount of mixing time is performed. Adequate mixing improves sample integrity, quality, and reliability.
- an accelerometer may be integrated with the tube 20 such that motion representative of mixing may be identified, recorded, and outputted. The output may be in a form that is visually apparent to the user or optionally may be discreet such that the output may be interrogated by a device remote from the tube (i.e., a reading from a hand-held scanner).
- a label is applied to a portion of tube 20 , wherein the backside 22 a of label 22 or the surface affixed or is fixable to the outside wall surface of tube 20 includes fill range indicator 40 .
- Such indicator 40 may comprise some form of pre-printed marking or shape specific marking, such as a black solid indicator portion or a cut, cutout, or visible perforation portion. The color, shading, pattern, and shape of such portions may vary as long as each is recognizable by the user.
- indicator 40 comprises a low fill indicator 40 a , situated at the bottom boundary of indicator 40 and a high fill indicator 40 b , situated at the upper boundary of indicator 40 .
- one of either a low fill indicator 40 a or high fill indicator 40 b may be utilized.
- the low fill indicator 40 a and the high fill indicator 40 b set the lower and upper limits for drawing a sample from a sample source (i.e. Patient's venous blood), such that sufficient sample amounts are collected to effectuate certain tests and to effectuate adequate reagent to sample mixing ratios and proper centrifugation considerations or conditions.
- the word “fill” or some other word indicative of the indicator's purpose may be displayed in the indicator area.
- High fill, low fill, and generic fill indicators may comprise boundaries of each limit, or optionally may include a filled or empty space area correlating to a desired fill range.
- the desired fill range may correlate to the quantity of reagents or additives deployed into the tube prior to use or at the point of manufacture to ensure proper sample to additive ration.
- the fill indicators ( 40 a and/or 40 b ) are preferably disposed on that portion of label 22 such that a user may interpret the level or quantity of sample collected from the patient into the container, by looking through a portion of the generally clear sidewall of tube 20 .
- label 22 comprises on a backside 22 a information pertaining to at least one of a manufacture catalog number, identifiable bar code, shelf life, lot identification number, or container specific identifier of tube 20 , wherein the backside is adhered to the sidewall of tube 20 .
- the label 22 further comprises on its other side (opposite of 22 a ) information specific to a sample intended to be placed or already placed into the container of which the label 22 is adhered to and/or information specific to a patient in a hospital.
- label 22 comprises on a first side, a fill indication correlating to the proper draw fill volume for a first tube, wherein the backside 22 a of label 22 or the surface affixed or ad fixable to the outside wall surface of tube 20 includes fill range indicator 40 .
- Such indicator 40 may comprise some form of pre-printed marking or shape specific marking, such as a black solid indicator portion or a cut, cutout, or visible perforation portion. The color, shading, pattern, and shape of such portions may vary, as long as each are recognizable by the user.
- indicator 40 comprises a low fill indicator 40 a situated at the bottom boundary of indicator 40 and a high fill indicator 40 b situated at the upper boundary of indicator 40 .
- label 22 includes hemolysis color indicator 50 , possibly in the form of a chart or scale.
- the indicator 50 may be displayed on the tube facing side, the side opposite the tube facing side, or optionally both. Additionally, the hemolysis color indicator 50 may be printed directly onto a tube 20 rather than on a label applicable to a tube 20 .
- One method for measuring levels of hemolysis i.e., the breaking of the cell membranes of red blood cells, is visually identifying the color of all or a portion of a blood sample. For example, in many instances, the shade of the serum that resides above the hematocrit for a blood sample is indicative of general qualitative hemolysis levels, such as zero, trace (or slight), moderate, and gross (or severe).
- Such indication may be displayed by including a color scale on blood containment device having different hemolysis level terminologies associated with and printed on the hemolysis scale.
- Some examples of scales/terminologies that can be included to convey for measuring levels of hemolysis are: a 0, +1, +2, and +3 scale; a 0, 1+, 2+, and 3+ scale; 0, 1, 2, and 3 scale; a 0, +, ++, and +++ scale; or a zero, trace, +, ++, and +++ scale.
- the color scale for indicating hemolysis ranges from a light yellow to a dark reddish orange.
- a Pantome color scheme may be chosen to represent variances between the low and high color indicators. Other indications of hemolysis levels may be provided.
- a barcode or some other machine readable data that is unique to each container, either unique to all container, or optionally unique to a subset of all containers produced. Such information may also be used for storage of additional data associated with container, such as container manufacturer information, container type, intended draw size information, and the like. In addition, patient-specific, test-specific, or other application-specific information may be stored (i.e., electronically) and associated with the container's unique identifier.
- the machine readable information may be provided on a container's permanent label, container's removable label, the container itself, or some combination thereof. Such design may allow for less information to be provided by users of the tube and/or fewer labels to be manually affixed by users.
- RFID tags may be passive in nature with an electronic device having some type of reading/scanning mechanism to receive identification information off the tag.
- the tag is active in nature in which an electronic device is used to receive a signal generated by or from the tag.
- the tags may be writeable, readable, or both. With such a system, the need for more conventional type labeling having machine readable or human readable information may be complemented or obviated.
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Clinical Laboratory Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Physics & Mathematics (AREA)
- Physics & Mathematics (AREA)
- Engineering & Computer Science (AREA)
- Theoretical Computer Science (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
- Sampling And Sample Adjustment (AREA)
- Labeling Devices (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
- Details Of Rigid Or Semi-Rigid Containers (AREA)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US12/278,642 US20100279397A1 (en) | 2006-02-08 | 2007-02-08 | Biological specimen collection and storage devices |
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US77192306P | 2006-02-08 | 2006-02-08 | |
PCT/US2007/003437 WO2007092585A2 (en) | 2006-02-08 | 2007-02-08 | Biological specimen collection and storage devices |
US12/278,642 US20100279397A1 (en) | 2006-02-08 | 2007-02-08 | Biological specimen collection and storage devices |
Related Parent Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2007/003437 A-371-Of-International WO2007092585A2 (en) | 2006-02-08 | 2007-02-08 | Biological specimen collection and storage devices |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US14/334,030 Continuation US20140328734A1 (en) | 2006-02-08 | 2014-07-17 | Biological Specimen Collection and Storage Devices |
Publications (1)
Publication Number | Publication Date |
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US20100279397A1 true US20100279397A1 (en) | 2010-11-04 |
Family
ID=38345816
Family Applications (4)
Application Number | Title | Priority Date | Filing Date |
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US12/278,671 Active 2028-10-11 US8630016B2 (en) | 2006-02-08 | 2007-02-08 | Label processor and method relating thereto |
US12/278,642 Abandoned US20100279397A1 (en) | 2006-02-08 | 2007-02-08 | Biological specimen collection and storage devices |
US12/278,658 Active 2030-11-20 US9724690B2 (en) | 2006-02-08 | 2007-02-08 | Blood collection device, method, and system for using the same |
US14/334,030 Abandoned US20140328734A1 (en) | 2006-02-08 | 2014-07-17 | Biological Specimen Collection and Storage Devices |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
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US12/278,671 Active 2028-10-11 US8630016B2 (en) | 2006-02-08 | 2007-02-08 | Label processor and method relating thereto |
Family Applications After (2)
Application Number | Title | Priority Date | Filing Date |
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US12/278,658 Active 2030-11-20 US9724690B2 (en) | 2006-02-08 | 2007-02-08 | Blood collection device, method, and system for using the same |
US14/334,030 Abandoned US20140328734A1 (en) | 2006-02-08 | 2014-07-17 | Biological Specimen Collection and Storage Devices |
Country Status (7)
Country | Link |
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US (4) | US8630016B2 (zh) |
EP (3) | EP1983891B1 (zh) |
JP (3) | JP5412117B2 (zh) |
CN (5) | CN104859908B (zh) |
CA (3) | CA2641861C (zh) |
ES (2) | ES2477874T3 (zh) |
WO (3) | WO2007092586A2 (zh) |
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US8512796B2 (en) | 2009-05-13 | 2013-08-20 | Si02 Medical Products, Inc. | Vessel inspection apparatus and methods |
US9272095B2 (en) | 2011-04-01 | 2016-03-01 | Sio2 Medical Products, Inc. | Vessels, contact surfaces, and coating and inspection apparatus and methods |
US9458536B2 (en) | 2009-07-02 | 2016-10-04 | Sio2 Medical Products, Inc. | PECVD coating methods for capped syringes, cartridges and other articles |
US9545360B2 (en) | 2009-05-13 | 2017-01-17 | Sio2 Medical Products, Inc. | Saccharide protective coating for pharmaceutical package |
US9554968B2 (en) | 2013-03-11 | 2017-01-31 | Sio2 Medical Products, Inc. | Trilayer coated pharmaceutical packaging |
US9662450B2 (en) | 2013-03-01 | 2017-05-30 | Sio2 Medical Products, Inc. | Plasma or CVD pre-treatment for lubricated pharmaceutical package, coating process and apparatus |
US9664626B2 (en) | 2012-11-01 | 2017-05-30 | Sio2 Medical Products, Inc. | Coating inspection method |
US9764093B2 (en) | 2012-11-30 | 2017-09-19 | Sio2 Medical Products, Inc. | Controlling the uniformity of PECVD deposition |
US9863042B2 (en) | 2013-03-15 | 2018-01-09 | Sio2 Medical Products, Inc. | PECVD lubricity vessel coating, coating process and apparatus providing different power levels in two phases |
US9878101B2 (en) | 2010-11-12 | 2018-01-30 | Sio2 Medical Products, Inc. | Cyclic olefin polymer vessels and vessel coating methods |
US9903782B2 (en) | 2012-11-16 | 2018-02-27 | Sio2 Medical Products, Inc. | Method and apparatus for detecting rapid barrier coating integrity characteristics |
US9937099B2 (en) | 2013-03-11 | 2018-04-10 | Sio2 Medical Products, Inc. | Trilayer coated pharmaceutical packaging with low oxygen transmission rate |
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