UA98151C2 - СПОСОБ СИНТЕЗА 9α-ГИДРОКСИСТЕРОИДОВ - Google Patents
СПОСОБ СИНТЕЗА 9α-ГИДРОКСИСТЕРОИДОВInfo
- Publication number
- UA98151C2 UA98151C2 UAA201001164A UAA201001164A UA98151C2 UA 98151 C2 UA98151 C2 UA 98151C2 UA A201001164 A UAA201001164 A UA A201001164A UA A201001164 A UAA201001164 A UA A201001164A UA 98151 C2 UA98151 C2 UA 98151C2
- Authority
- UA
- Ukraine
- Prior art keywords
- hydroxy
- synthesis
- steroid derivatives
- bioconversion
- meaning
- Prior art date
Links
- 230000015572 biosynthetic process Effects 0.000 title abstract 2
- 238000003786 synthesis reaction Methods 0.000 title abstract 2
- 241001503673 Nocardia farcinica Species 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000008021 deposition Effects 0.000 abstract 1
- 230000000640 hydroxylating effect Effects 0.000 abstract 1
- 244000005700 microbiome Species 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
- C07J21/001—Lactones
- C07J21/003—Lactones at position 17
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P33/00—Preparation of steroids
- C12P33/12—Acting on D ring
- C12P33/16—Acting at 17 position
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- General Chemical & Material Sciences (AREA)
- Microbiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
HU0700461A HU227304B1 (en) | 2007-07-04 | 2007-07-04 | Process for producing 9alpha-hydroxy-steroids |
PCT/HU2008/000078 WO2009004394A2 (en) | 2007-07-04 | 2008-06-30 | PROCESS FOR THE SYNTHESIS OF 9α-HYDROXY-STEROIDS |
Publications (1)
Publication Number | Publication Date |
---|---|
UA98151C2 true UA98151C2 (ru) | 2012-04-25 |
Family
ID=89987625
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
UAA201001164A UA98151C2 (ru) | 2007-07-04 | 2008-06-30 | СПОСОБ СИНТЕЗА 9α-ГИДРОКСИСТЕРОИДОВ |
Country Status (10)
Country | Link |
---|---|
US (1) | US8367394B2 (ru) |
EP (1) | EP2173761B1 (ru) |
JP (1) | JP2010531660A (ru) |
KR (1) | KR20100038297A (ru) |
CN (1) | CN101687903A (ru) |
CA (1) | CA2689422A1 (ru) |
EA (1) | EA015734B1 (ru) |
HU (1) | HU227304B1 (ru) |
UA (1) | UA98151C2 (ru) |
WO (1) | WO2009004394A2 (ru) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103343155B (zh) * | 2013-06-26 | 2015-04-01 | 山西祖源工贸有限公司 | 一种制备9a-羟基雄烯二酮的方法 |
CN103361394B (zh) * | 2013-08-07 | 2016-08-17 | 中国科学院上海高等研究院 | 利用微生物转化制备9α-羟基-雄烯二酮的方法 |
CN108277170B (zh) * | 2017-09-29 | 2020-06-05 | 沈阳博泰生物制药有限公司 | 一种新金分枝杆菌及其在制备9-羟基黄体酮中的应用 |
CN110564652B (zh) * | 2019-10-01 | 2022-06-14 | 江苏佳尔科药业集团股份有限公司 | 分枝杆菌及其应用 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4035236A (en) | 1975-10-24 | 1977-07-12 | The Upjohn Company | Process for preparing 9α-hydroxyandrostenedione |
US4029549A (en) | 1976-03-26 | 1977-06-14 | The Upjohn Company | Process of producing 9α-hydroxy-3-ketobisnorchol-4-en-22-oic with mycobacterium fortuitum |
US4397947A (en) * | 1981-06-12 | 1983-08-09 | G. D. Searle & Co. | Microbial process for 9α-hydroxylation of steroids |
CN100384866C (zh) * | 1995-12-11 | 2008-04-30 | G·D·瑟尔公司 | 制备7α-羧基9,11-环氧甾族化合物的方法和其中使用的中间体以及烯双键环氧化作用的一般方法 |
-
2007
- 2007-07-04 HU HU0700461A patent/HU227304B1/hu unknown
-
2008
- 2008-06-30 JP JP2010514150A patent/JP2010531660A/ja active Pending
- 2008-06-30 US US12/665,351 patent/US8367394B2/en not_active Expired - Fee Related
- 2008-06-30 EP EP08776244.9A patent/EP2173761B1/en active Active
- 2008-06-30 WO PCT/HU2008/000078 patent/WO2009004394A2/en active Application Filing
- 2008-06-30 UA UAA201001164A patent/UA98151C2/ru unknown
- 2008-06-30 CN CN200880023394A patent/CN101687903A/zh active Pending
- 2008-06-30 EA EA201070087A patent/EA015734B1/ru not_active IP Right Cessation
- 2008-06-30 KR KR1020097025817A patent/KR20100038297A/ko not_active Application Discontinuation
- 2008-06-30 CA CA002689422A patent/CA2689422A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
HU227304B1 (en) | 2011-02-28 |
EA201070087A1 (ru) | 2010-08-30 |
WO2009004394A8 (en) | 2010-01-14 |
CN101687903A (zh) | 2010-03-31 |
HU0700461D0 (en) | 2007-08-28 |
EP2173761B1 (en) | 2013-04-10 |
WO2009004394A3 (en) | 2009-05-07 |
US8367394B2 (en) | 2013-02-05 |
EA015734B1 (ru) | 2011-10-31 |
WO2009004394A2 (en) | 2009-01-08 |
JP2010531660A (ja) | 2010-09-30 |
EP2173761A2 (en) | 2010-04-14 |
CA2689422A1 (en) | 2009-01-08 |
HUP0700461A2 (en) | 2010-01-28 |
KR20100038297A (ko) | 2010-04-14 |
US20100209967A1 (en) | 2010-08-19 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
UA102817C2 (ru) | Способ синтеза агомелатина | |
AU2008303600A8 (en) | 1,1,1-trifluoro-2-hydroxy-3-phenylpropane derivatives | |
AU2010246102A8 (en) | Pesticidal compositions | |
UA102220C2 (ru) | Способ синтеза агомелатина | |
IN2012DN02751A (ru) | ||
WO2009049274A3 (en) | Microorganism engineered to produce isopropanol | |
MX2009003586A (es) | Procedimiento de dehidrogenacion-halogenacion para la produccion de (hidro)fluoroalquenos de c3-c6. | |
AU2008258588A8 (en) | Anti -inflammatory substituted cyclobutenedione compounds | |
MY153763A (en) | Quinazolinedione derivatives, preparation thereof and therapeutic uses thereof | |
TN2010000219A1 (en) | 5-[(3,3,3-trifluoro-2-hydroxy-1-arylpropyl)amino]-1h-quinolin-2-ones, a process for their production and their use as anti-inflammatory agents | |
UA97638C2 (ru) | Способ синтеза ранелата стронция и его гидратов | |
TW200728310A (en) | Process for the preparation of ferri-succinylcasein | |
CR11463A (es) | Compuestos de piridilmetil-sulfonamida | |
UA98151C2 (ru) | СПОСОБ СИНТЕЗА 9α-ГИДРОКСИСТЕРОИДОВ | |
MX2010002453A (es) | Procedimiento para la preparacion de derivados de 2,2-difluoroetilamina mediante hidrogenacion de imina. | |
HK1103420A1 (en) | Compound ws 727713 | |
WO2008117871A1 (ja) | 含窒素レドックス触媒 | |
UA106195C2 (ru) | Способ синтеза агомелатина | |
WO2011016052A3 (en) | Process for preparing pregabalin | |
UA102816C2 (ru) | Способ синтеза кристаллической формы v агомелатина | |
SG166064A1 (en) | Process for preparing substituted 1,4-quinone methides | |
HK1103304A1 (en) | Biotransformation of colchicinoid compounds | |
WO2008120486A1 (ja) | 新規微生物 | |
MX2010008693A (es) | Compuestos organicos. | |
WO2011045546A3 (fr) | Synthèse de polyuréthane par autocondensation |