UA98151C2 - СПОСОБ СИНТЕЗА 9α-ГИДРОКСИСТЕРОИДОВ - Google Patents
СПОСОБ СИНТЕЗА 9α-ГИДРОКСИСТЕРОИДОВInfo
- Publication number
- UA98151C2 UA98151C2 UAA201001164A UAA201001164A UA98151C2 UA 98151 C2 UA98151 C2 UA 98151C2 UA A201001164 A UAA201001164 A UA A201001164A UA A201001164 A UAA201001164 A UA A201001164A UA 98151 C2 UA98151 C2 UA 98151C2
- Authority
- UA
- Ukraine
- Prior art keywords
- hydroxy
- synthesis
- steroid derivatives
- bioconversion
- meaning
- Prior art date
Links
- 230000015572 biosynthetic process Effects 0.000 title abstract 2
- 238000003786 synthesis reaction Methods 0.000 title abstract 2
- 241001503673 Nocardia farcinica Species 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000008021 deposition Effects 0.000 abstract 1
- 230000000640 hydroxylating effect Effects 0.000 abstract 1
- 244000005700 microbiome Species 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
- C07J21/001—Lactones
- C07J21/003—Lactones at position 17
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P33/00—Preparation of steroids
- C12P33/12—Acting on D ring
- C12P33/16—Acting at 17 position
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- General Chemical & Material Sciences (AREA)
- Microbiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HU0700461A HU227304B1 (en) | 2007-07-04 | 2007-07-04 | Process for producing 9alpha-hydroxy-steroids |
| PCT/HU2008/000078 WO2009004394A2 (en) | 2007-07-04 | 2008-06-30 | PROCESS FOR THE SYNTHESIS OF 9α-HYDROXY-STEROIDS |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| UA98151C2 true UA98151C2 (ru) | 2012-04-25 |
Family
ID=89987625
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UAA201001164A UA98151C2 (ru) | 2007-07-04 | 2008-06-30 | СПОСОБ СИНТЕЗА 9α-ГИДРОКСИСТЕРОИДОВ |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US8367394B2 (de) |
| EP (1) | EP2173761B1 (de) |
| JP (1) | JP2010531660A (de) |
| KR (1) | KR20100038297A (de) |
| CN (1) | CN101687903A (de) |
| CA (1) | CA2689422A1 (de) |
| EA (1) | EA015734B1 (de) |
| HU (1) | HU227304B1 (de) |
| UA (1) | UA98151C2 (de) |
| WO (1) | WO2009004394A2 (de) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103343155B (zh) * | 2013-06-26 | 2015-04-01 | 山西祖源工贸有限公司 | 一种制备9a-羟基雄烯二酮的方法 |
| CN103361394B (zh) * | 2013-08-07 | 2016-08-17 | 中国科学院上海高等研究院 | 利用微生物转化制备9α-羟基-雄烯二酮的方法 |
| CN108277170B (zh) * | 2017-09-29 | 2020-06-05 | 沈阳博泰生物制药有限公司 | 一种新金分枝杆菌及其在制备9-羟基黄体酮中的应用 |
| CN110564652B (zh) * | 2019-10-01 | 2022-06-14 | 江苏佳尔科药业集团股份有限公司 | 分枝杆菌及其应用 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4035236A (en) | 1975-10-24 | 1977-07-12 | The Upjohn Company | Process for preparing 9α-hydroxyandrostenedione |
| US4029549A (en) | 1976-03-26 | 1977-06-14 | The Upjohn Company | Process of producing 9α-hydroxy-3-ketobisnorchol-4-en-22-oic with mycobacterium fortuitum |
| US4397947A (en) * | 1981-06-12 | 1983-08-09 | G. D. Searle & Co. | Microbial process for 9α-hydroxylation of steroids |
| ATE365171T1 (de) * | 1995-12-11 | 2007-07-15 | Searle Llc | Verfahren zur herstellung einer epoxyverbindung |
-
2007
- 2007-07-04 HU HU0700461A patent/HU227304B1/hu unknown
-
2008
- 2008-06-30 EA EA201070087A patent/EA015734B1/ru not_active IP Right Cessation
- 2008-06-30 JP JP2010514150A patent/JP2010531660A/ja active Pending
- 2008-06-30 US US12/665,351 patent/US8367394B2/en not_active Expired - Fee Related
- 2008-06-30 CN CN200880023394A patent/CN101687903A/zh active Pending
- 2008-06-30 KR KR1020097025817A patent/KR20100038297A/ko not_active Application Discontinuation
- 2008-06-30 CA CA002689422A patent/CA2689422A1/en not_active Abandoned
- 2008-06-30 WO PCT/HU2008/000078 patent/WO2009004394A2/en active Application Filing
- 2008-06-30 EP EP08776244.9A patent/EP2173761B1/de active Active
- 2008-06-30 UA UAA201001164A patent/UA98151C2/ru unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US8367394B2 (en) | 2013-02-05 |
| EP2173761B1 (de) | 2013-04-10 |
| EP2173761A2 (de) | 2010-04-14 |
| WO2009004394A3 (en) | 2009-05-07 |
| HUP0700461A2 (en) | 2010-01-28 |
| CN101687903A (zh) | 2010-03-31 |
| HU0700461D0 (en) | 2007-08-28 |
| WO2009004394A8 (en) | 2010-01-14 |
| EA201070087A1 (ru) | 2010-08-30 |
| HU227304B1 (en) | 2011-02-28 |
| CA2689422A1 (en) | 2009-01-08 |
| KR20100038297A (ko) | 2010-04-14 |
| EA015734B1 (ru) | 2011-10-31 |
| WO2009004394A2 (en) | 2009-01-08 |
| JP2010531660A (ja) | 2010-09-30 |
| US20100209967A1 (en) | 2010-08-19 |
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