UA97234C2 - Раствор хлорида натрия для восстановления влагосодержания композиции лиофилизированного фактора ix - Google Patents
Раствор хлорида натрия для восстановления влагосодержания композиции лиофилизированного фактора ixInfo
- Publication number
- UA97234C2 UA97234C2 UAA200807432A UAA200807432A UA97234C2 UA 97234 C2 UA97234 C2 UA 97234C2 UA A200807432 A UAA200807432 A UA A200807432A UA A200807432 A UAA200807432 A UA A200807432A UA 97234 C2 UA97234 C2 UA 97234C2
- Authority
- UA
- Ukraine
- Prior art keywords
- formulation
- sodium chloride
- chloride solution
- reconstituting lyophilized
- lyophilized factor
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
- A61K38/482—Serine endopeptidases (3.4.21)
- A61K38/4846—Factor VII (3.4.21.21); Factor IX (3.4.21.22); Factor Xa (3.4.21.6); Factor XI (3.4.21.27); Factor XII (3.4.21.38)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
- A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Inorganic Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Dermatology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Organic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Изобретение касается способа получения композиции Фактора IX для предотвращения агглютинации эритроцитов при внутривенной инъекции, который включает добавление приблизительно от 25 мм до 150 мм раствора хлорида натрия к композиции лиофилизированного Фактора IX с получением композиции, готовой для внутривенной инъекции, причем полученная композиция является приблизительно изотонической относительно плазмы или является немного гипотонической или немного гипертонической относительно плазмы.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US73222105P | 2005-11-01 | 2005-11-01 | |
PCT/US2006/042258 WO2007053533A2 (en) | 2005-11-01 | 2006-10-27 | Sodium chloride solution for drug reconstitution or dilution |
Publications (1)
Publication Number | Publication Date |
---|---|
UA97234C2 true UA97234C2 (ru) | 2012-01-25 |
Family
ID=37801586
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
UAA200807432A UA97234C2 (ru) | 2005-11-01 | 2006-10-27 | Раствор хлорида натрия для восстановления влагосодержания композиции лиофилизированного фактора ix |
Country Status (31)
Country | Link |
---|---|
US (4) | US20070135343A1 (ru) |
EP (3) | EP3593790A1 (ru) |
JP (1) | JP5555425B2 (ru) |
KR (2) | KR20110128957A (ru) |
CN (1) | CN101351190B (ru) |
AR (2) | AR056748A1 (ru) |
AU (1) | AU2006308921C1 (ru) |
BR (1) | BRPI0618133A2 (ru) |
CA (1) | CA2626531C (ru) |
CR (1) | CR9958A (ru) |
DK (2) | DK3225233T3 (ru) |
EC (1) | ECSP088485A (ru) |
ES (2) | ES2749574T3 (ru) |
FI (1) | FI1942868T4 (ru) |
FR (1) | FR20C1005I1 (ru) |
GT (1) | GT200800037A (ru) |
HK (1) | HK1245090B (ru) |
HU (4) | HUE033949T2 (ru) |
IL (1) | IL190843A (ru) |
LU (1) | LUC00035I2 (ru) |
MY (1) | MY184364A (ru) |
NO (1) | NO347263B1 (ru) |
NZ (1) | NZ567685A (ru) |
PE (3) | PE20070714A1 (ru) |
PL (2) | PL1942868T5 (ru) |
PT (2) | PT1942868T (ru) |
RU (1) | RU2432157C2 (ru) |
SI (2) | SI1942868T2 (ru) |
TW (1) | TWI480063B (ru) |
UA (1) | UA97234C2 (ru) |
WO (1) | WO2007053533A2 (ru) |
Families Citing this family (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PL1942868T5 (pl) | 2005-11-01 | 2023-12-27 | Wyeth Llc | Roztwór chlorku sodu do odtwarzania lub rozcieńczania leku |
US7833527B2 (en) | 2006-10-02 | 2010-11-16 | Amgen Inc. | Methods of treating psoriasis using IL-17 Receptor A antibodies |
US8431011B2 (en) | 2008-01-31 | 2013-04-30 | Abbott Diabetes Care Inc. | Method for automatically and rapidly distinguishing between control and sample solutions in a biosensor strip |
CN102665691B (zh) * | 2009-11-17 | 2015-05-27 | 益普生制药股份有限公司 | hGH和rhIGF-1组合的制剂 |
US9427186B2 (en) | 2009-12-04 | 2016-08-30 | Endomagnetics Ltd. | Magnetic probe apparatus |
US10634741B2 (en) | 2009-12-04 | 2020-04-28 | Endomagnetics Ltd. | Magnetic probe apparatus |
SG10201604093XA (en) | 2010-01-15 | 2016-07-28 | Kirin Amgen Inc | Antibody formulation and therapeutic regimens |
WO2011109365A2 (en) * | 2010-03-01 | 2011-09-09 | Progenics Pharmaceuticals, Inc. | Concentrated protein formulations and uses thereof |
CN103140237A (zh) | 2010-07-09 | 2013-06-05 | 比奥根艾迪克依蒙菲利亚公司 | 因子ix多肽及其使用方法 |
US20150252345A1 (en) * | 2012-09-25 | 2015-09-10 | Biogen Idec Ma Inc. | Methods of Using FIX Polypeptides |
CN105283202B (zh) | 2013-03-11 | 2019-04-23 | 安都磁学有限公司 | 用于淋巴结检测的低渗溶液 |
US9234877B2 (en) | 2013-03-13 | 2016-01-12 | Endomagnetics Ltd. | Magnetic detector |
US9239314B2 (en) | 2013-03-13 | 2016-01-19 | Endomagnetics Ltd. | Magnetic detector |
TWI788044B (zh) * | 2013-03-15 | 2022-12-21 | 美商百歐維拉提夫治療公司 | 因子ix多肽調配物 |
FR3005420B1 (fr) | 2013-05-07 | 2015-09-18 | Erytech Pharma | Procede de stabilisation de suspensions d'erythrocytes encapsulant un principe actif, suspensions obtenues. |
AU2015236340B2 (en) * | 2014-03-24 | 2020-02-06 | Bioverativ Therapeutics Inc. | Lyophilized factor IX formulations |
US9351945B1 (en) * | 2015-02-27 | 2016-05-31 | John Daniel Dobak, III | Reduction of adipose tissue |
GB2536703B (en) * | 2015-03-27 | 2020-12-02 | Ge Healthcare Bio Sciences Ab | Method for baseline correction in a chromatogram |
EP3081942A1 (en) * | 2015-04-17 | 2016-10-19 | Roche Diagniostics GmbH | Pressure transmission liquid for cellular analyzer, cellular analyzer and method for analyzing a liquid cellular sample |
ES2833377T3 (es) | 2015-06-04 | 2021-06-15 | Endomagnetics Ltd | Materiales marcadores y formas de localizar un marcador magnético |
US10124021B2 (en) * | 2016-12-23 | 2018-11-13 | Andrew L. Gostine | Intravenous fluid |
CN111295094A (zh) | 2017-10-09 | 2020-06-16 | 泰尔茂比司特生物技术有限公司 | 冻干容器及使用冻干容器的方法 |
JP2022525742A (ja) | 2019-03-14 | 2022-05-19 | テルモ ビーシーティー バイオテクノロジーズ,エルエルシー | 凍結乾燥用ローディングトレイ組立体及びシステム |
US20200345658A1 (en) * | 2019-05-01 | 2020-11-05 | Southwest Research Institute | Compositions Of Dimethyl Trisulfide (DMTS) As A Cyanide Antidote |
IL272145A (en) * | 2020-01-20 | 2021-07-29 | Stem Cell Medicine Ltd | Cosmetic preparations with protein concentrate from a conditioned growth medium of stem cells from adipose tissue |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3717708A (en) * | 1968-10-24 | 1973-02-20 | Cutter Lab | Blood coagulation complex |
US4364861A (en) | 1980-05-27 | 1982-12-21 | Cutter Laboratories, Inc. | Blood-coagulation-promoting products and methods of preparing them |
US6372716B1 (en) | 1994-04-26 | 2002-04-16 | Genetics Institute, Inc. | Formulations for factor IX |
DK2193809T3 (en) | 1999-02-22 | 2015-05-26 | Univ Connecticut | The albumin-free Factor VIII formulation |
US20010031721A1 (en) * | 1999-05-05 | 2001-10-18 | Chandra Webb | Highly concentrated, lyophilized, and liquid factor IX formulations |
DK1324776T4 (en) * | 2000-10-12 | 2018-05-28 | Genentech Inc | CONCENTRATED PROTEIN FORMULATIONS WITH REDUCED VISCOSITY |
EP3378470A1 (en) * | 2003-12-19 | 2018-09-26 | Novo Nordisk Health Care AG | Stabilised compositions of factor vii polypeptides |
BRPI0509117A (pt) * | 2004-03-04 | 2007-08-28 | Wyeth Corp | método de liofilização para melhorar a cristalização de excipientes |
PL1942868T5 (pl) | 2005-11-01 | 2023-12-27 | Wyeth Llc | Roztwór chlorku sodu do odtwarzania lub rozcieńczania leku |
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2006
- 2006-10-27 PL PL06827036.2T patent/PL1942868T5/pl unknown
- 2006-10-27 PT PT68270362T patent/PT1942868T/pt unknown
- 2006-10-27 EP EP19189599.4A patent/EP3593790A1/en not_active Withdrawn
- 2006-10-27 PL PL17166616T patent/PL3225233T3/pl unknown
- 2006-10-27 HU HUE06827036A patent/HUE033949T2/hu unknown
- 2006-10-27 EP EP17166616.7A patent/EP3225233B1/en not_active Revoked
- 2006-10-27 ES ES17166616T patent/ES2749574T3/es active Active
- 2006-10-27 DK DK17166616.7T patent/DK3225233T3/da active
- 2006-10-27 ES ES06827036T patent/ES2627684T5/es active Active
- 2006-10-27 PE PE2006001318A patent/PE20070714A1/es not_active Application Discontinuation
- 2006-10-27 PT PT171666167T patent/PT3225233T/pt unknown
- 2006-10-27 SI SI200632172T patent/SI1942868T2/sl unknown
- 2006-10-27 NO NO20082180A patent/NO347263B1/no unknown
- 2006-10-27 HU HUE17166616A patent/HUE045421T2/hu unknown
- 2006-10-27 CN CN2006800400807A patent/CN101351190B/zh active Active
- 2006-10-27 UA UAA200807432A patent/UA97234C2/ru unknown
- 2006-10-27 MY MYPI20081347A patent/MY184364A/en unknown
- 2006-10-27 RU RU2008119514/15A patent/RU2432157C2/ru active
- 2006-10-27 KR KR1020117027131A patent/KR20110128957A/ko not_active Application Discontinuation
- 2006-10-27 AU AU2006308921A patent/AU2006308921C1/en active Active
- 2006-10-27 WO PCT/US2006/042258 patent/WO2007053533A2/en active Application Filing
- 2006-10-27 TW TW095139724A patent/TWI480063B/zh active
- 2006-10-27 DK DK06827036.2T patent/DK1942868T5/da active
- 2006-10-27 US US11/589,002 patent/US20070135343A1/en not_active Abandoned
- 2006-10-27 NZ NZ567685A patent/NZ567685A/en unknown
- 2006-10-27 CA CA2626531A patent/CA2626531C/en active Active
- 2006-10-27 PE PE2011000653A patent/PE20110803A1/es not_active Application Discontinuation
- 2006-10-27 KR KR1020087013252A patent/KR101126670B1/ko active IP Right Grant
- 2006-10-27 PE PE2015001729A patent/PE20151284A1/es not_active Application Discontinuation
- 2006-10-27 EP EP06827036.2A patent/EP1942868B2/en active Active
- 2006-10-27 BR BRPI0618133-3A patent/BRPI0618133A2/pt not_active Application Discontinuation
- 2006-10-27 JP JP2008538945A patent/JP5555425B2/ja active Active
- 2006-10-27 SI SI200632348T patent/SI3225233T1/sl unknown
- 2006-10-31 AR ARP060104769A patent/AR056748A1/es not_active Application Discontinuation
-
2008
- 2008-04-14 IL IL190843A patent/IL190843A/en active IP Right Grant
- 2008-04-17 GT GT200800037A patent/GT200800037A/es unknown
- 2008-05-07 CR CR9958A patent/CR9958A/es not_active Application Discontinuation
- 2008-05-30 EC EC2008008485A patent/ECSP088485A/es unknown
-
2016
- 2016-10-07 US US15/288,860 patent/US20170021022A1/en not_active Abandoned
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2017
- 2017-09-25 LU LU00035C patent/LUC00035I2/fr unknown
- 2017-09-27 HU HUS1700035C patent/HUS1700035I1/hu unknown
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2018
- 2018-04-04 HK HK18104477.4A patent/HK1245090B/zh unknown
- 2018-07-06 AR ARP180101902 patent/AR112443A2/es not_active Application Discontinuation
-
2019
- 2019-12-20 US US16/723,563 patent/US20200138952A1/en not_active Abandoned
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2020
- 2020-01-31 HU HUS2000003C patent/HUS2000003I1/hu unknown
- 2020-02-10 FR FR20C1005C patent/FR20C1005I1/fr active Active
- 2020-07-14 US US16/946,998 patent/US20200338199A1/en not_active Abandoned
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2023
- 2023-03-17 FI FIEP06827036.2T patent/FI1942868T4/fi active
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