UA88688C2 - Фенилсодержащие n-ацилные производные аминов и аминокислот, способ их получения, фармацевтическая композиция и их применение - Google Patents
Фенилсодержащие n-ацилные производные аминов и аминокислот, способ их получения, фармацевтическая композиция и их применениеInfo
- Publication number
- UA88688C2 UA88688C2 UAA200711752A UAA200711752A UA88688C2 UA 88688 C2 UA88688 C2 UA 88688C2 UA A200711752 A UAA200711752 A UA A200711752A UA A200711752 A UAA200711752 A UA A200711752A UA 88688 C2 UA88688 C2 UA 88688C2
- Authority
- UA
- Ukraine
- Prior art keywords
- phenyl
- pharmaceutical composition
- methods
- production
- acyl amine
- Prior art date
Links
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 150000003862 amino acid derivatives Chemical class 0.000 title 1
- 150000001412 amines Chemical class 0.000 abstract 2
- 230000000035 biogenic effect Effects 0.000 abstract 2
- 230000000694 effects Effects 0.000 abstract 2
- 235000001014 amino acid Nutrition 0.000 abstract 1
- 150000001413 amino acids Chemical class 0.000 abstract 1
- 230000000202 analgesic effect Effects 0.000 abstract 1
- 229940035676 analgesics Drugs 0.000 abstract 1
- 239000000730 antalgic agent Substances 0.000 abstract 1
- 230000001430 anti-depressive effect Effects 0.000 abstract 1
- 230000000141 anti-hypoxic effect Effects 0.000 abstract 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- 230000000648 anti-parkinson Effects 0.000 abstract 1
- 239000000935 antidepressant agent Substances 0.000 abstract 1
- 229940005513 antidepressants Drugs 0.000 abstract 1
- 239000000939 antiparkinson agent Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 238000001723 curing Methods 0.000 abstract 1
- 239000008177 pharmaceutical agent Substances 0.000 abstract 1
- 230000003389 potentiating effect Effects 0.000 abstract 1
- 239000002599 prostaglandin synthase inhibitor Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/02—Preparation of carboxylic acid amides from carboxylic acids or from esters, anhydrides, or halides thereof by reaction with ammonia or amines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/12—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by halogen atoms or by nitro or nitroso groups
- C07C233/13—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by halogen atoms or by nitro or nitroso groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/14—Preparation of carboxylic acid amides by formation of carboxamide groups together with reactions not involving the carboxamide groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/02—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
- C07C233/11—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals with carbon atoms of carboxamide groups bound to carbon atoms of an unsaturated carbon skeleton containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/16—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
- C07C233/17—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
- C07C233/22—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom having the carbon atom of the carboxamide group bound to an acyclic carbon atom of a carbon skeleton containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/45—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups
- C07C233/46—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
- C07C233/51—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom having the carbon atom of the carboxamide group bound to an acyclic carbon atom of a carbon skeleton containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
- C07C235/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
- C07C235/32—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
- C07C235/34—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
- C07C237/20—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
- C07C237/22—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton having nitrogen atoms of amino groups bound to the carbon skeleton of the acid part, further acylated
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Psychology (AREA)
- Rheumatology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| RU2005108492/04A RU2309144C2 (ru) | 2005-03-25 | 2005-03-25 | Фенилсодержащие n-ацильные производные аминов, способ их получения, фармацевтическая композиция и их применение в качестве противовоспалительных и анальгетических средств |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| UA88688C2 true UA88688C2 (ru) | 2009-11-10 |
Family
ID=37024023
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UAA200711752A UA88688C2 (ru) | 2005-03-25 | 2006-03-24 | Фенилсодержащие n-ацилные производные аминов и аминокислот, способ их получения, фармацевтическая композиция и их применение |
Country Status (18)
| Country | Link |
|---|---|
| US (2) | US8309766B2 (enExample) |
| EP (1) | EP1876169B1 (enExample) |
| JP (1) | JP5384096B2 (enExample) |
| KR (1) | KR101383580B1 (enExample) |
| CN (1) | CN101180267B (enExample) |
| CA (1) | CA2602545C (enExample) |
| CY (1) | CY1117449T1 (enExample) |
| DK (1) | DK1876169T3 (enExample) |
| EA (1) | EA013644B1 (enExample) |
| ES (1) | ES2564238T3 (enExample) |
| HU (1) | HUE027009T2 (enExample) |
| MX (1) | MX2007011852A (enExample) |
| PL (1) | PL1876169T3 (enExample) |
| PT (1) | PT1876169E (enExample) |
| RU (1) | RU2309144C2 (enExample) |
| SI (1) | SI1876169T1 (enExample) |
| UA (1) | UA88688C2 (enExample) |
| WO (1) | WO2006101422A1 (enExample) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT1546088E (pt) | 2002-10-03 | 2015-03-16 | Novaremed Ltd | Compostos para utilização no tratamento de doenças auto-imunes, de doenças imuno-alérgicas e de rejeição de órgãos ou tecidos transplantados |
| US7674829B2 (en) | 2004-03-26 | 2010-03-09 | Novaremed Limited | Compounds for the treatment of AIDS and other viral diseases |
| GB0804213D0 (en) * | 2008-03-06 | 2008-04-16 | New Era Biotech Ltd | A method of printing or preventing pain |
| ES2507089T3 (es) * | 2008-04-29 | 2014-10-14 | F. Hoffmann-La Roche Ag | Derivados del ácido 4-dimetilaminobutírico |
| US8802734B2 (en) | 2009-09-09 | 2014-08-12 | Novaremed Limited | Method of treating or preventing pain |
| PL2475361T3 (pl) * | 2009-09-09 | 2020-07-13 | Novaremed Ltd. | N-podstawione benzenopropanoamidy do stosowania w leczeniu bólu i stanu zapalnego |
| WO2012026639A1 (ko) * | 2010-08-27 | 2012-03-01 | (주)네오팜 | 인간유래 항균 펩타이드의 분비를 촉진하는 신규화합물, 그 제조방법 및 이를 유효성분으로 함유하는 조성물 |
| GB201116335D0 (en) * | 2011-09-21 | 2011-11-02 | Novaremed Ltd | A method of treating or preventing affective disorders |
| ES2578377B1 (es) * | 2014-12-22 | 2017-05-04 | Consejo Superior De Investigaciones Científicas (Csic) | Compuestos moduladores del sensor neuronal de calcio dream y sus usos terapéuticos. |
| RU2690188C2 (ru) * | 2017-05-26 | 2019-05-31 | Общество С Ограниченной Ответственностью "Фарминтерпрайсез" | Новый мультитаргетный препарат для лечения заболеваний у млекопитающих |
| EP3672934A4 (en) | 2017-08-21 | 2021-05-05 | Plex Pharmaceuticals, Inc. | DOUBLE ACTING FKBP12 AND FKBP52 INHIBITORS |
| RU2678563C1 (ru) * | 2017-10-27 | 2019-01-30 | Михаил Владимирович Овчинников | Водорастворимые производные тирозина, обладающие анальгетическим, противовоспалительным и противоотечным действием |
| RU2697414C1 (ru) * | 2018-05-11 | 2019-08-14 | Общество с ограниченной ответственностью "АЙ БИ ДИ Терапевтикс" | Новый антагонист тахикининовых рецепторов и его применение |
| RU2727703C2 (ru) * | 2018-10-29 | 2020-07-23 | Общество С Ограниченной Ответственностью "Фарминтерпрайсез" | Новый способ получения (S)-2-(2-(4-гидроксифенил)ацетамидо)-3-фенилпропановой кислоты |
| RU2716258C1 (ru) * | 2019-07-30 | 2020-03-11 | Автономная некоммерческая образовательная организация высшего образования Сколковский институт науки и технологий | Пептидный антагонист нмда-рецептора |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2711656A1 (de) * | 1977-03-17 | 1978-09-21 | Basf Ag | Neue pyridin-3-ole |
| DE2861593D1 (en) * | 1977-06-29 | 1982-03-11 | Beecham Group Plc | Peptides, pharmaceutical compositions containing the peptides and a process for the preparation of the peptides |
| JPS57145891A (en) * | 1981-03-05 | 1982-09-09 | Sagami Chem Res Center | Optically active diphosphine ligand |
| JPS57193437A (en) * | 1981-05-21 | 1982-11-27 | Ajinomoto Co Inc | Amino acid derivative |
| ES8607214A1 (es) * | 1985-10-16 | 1986-06-01 | Gema Sa | Procedimiento enzimatico de resolucion de n-fenilacetil-ami-nocompuestos y purificacion de sus isomeros opticamente ac- tivos |
| USRE37160E1 (en) * | 1990-06-12 | 2001-05-01 | Rutgers, The State University | Synthesis of tyrosine derived diphenol monomers |
| US5403851A (en) * | 1994-04-05 | 1995-04-04 | Interneuron Pharmaceuticals, Inc. | Substituted tryptamines, phenalkylamines and related compounds |
| WO1997023202A1 (en) * | 1995-12-22 | 1997-07-03 | STATE OF OREGON, acting by and through THE OREGON STATE BOARD OF HIGHER EDUCATION, acting for and on behalf of THE OREGON HEALTH SCIENCES UNIVERSITYA ND THE UNIVERSITY OF OREGON, EUGENE OREGON | Subtype-selective nmda receptor ligands and the use thereof |
| US6319492B1 (en) * | 1996-11-27 | 2001-11-20 | Rutgers, The State University | Copolymers of tyrosine-based polyarylates and poly(alkylene oxides) |
| US5912225A (en) * | 1997-04-14 | 1999-06-15 | Johns Hopkins Univ. School Of Medicine | Biodegradable poly (phosphoester-co-desaminotyrosyl L-tyrosine ester) compounds, compositions, articles and methods for making and using the same |
| JPH11127894A (ja) * | 1997-10-30 | 1999-05-18 | Ono Pharmaceut Co Ltd | カルボキシペプチダーゼa活性測定方法および測定用キット |
| RU2123041C1 (ru) * | 1998-04-02 | 1998-12-10 | Пипия Гулади Эрастович | Бальзам "саратовский" |
| AU761458B2 (en) * | 1998-04-13 | 2003-06-05 | Rutgers, The State University | The construction of copolymer libraries |
| CA2329821A1 (en) * | 1998-04-27 | 1999-11-04 | Dashyant Dhanak | Ccr-3 receptor antagonists |
| US6414173B1 (en) * | 1998-07-02 | 2002-07-02 | University Of Maryland | Hypervalent silane and siloxane derivatives and the use thereof |
| KR100740962B1 (ko) * | 2000-03-09 | 2007-07-19 | 가부시끼가이샤 도꾸야마 | 4급 암모늄염의 보존 방법 |
| HUP0303085A2 (hu) * | 2000-09-27 | 2003-12-29 | The Procter & Gamble Co. | Melanokortin receptor ligandumok és ezeket tartalmazó gyógyszerkészítmények |
| PT1546088E (pt) * | 2002-10-03 | 2015-03-16 | Novaremed Ltd | Compostos para utilização no tratamento de doenças auto-imunes, de doenças imuno-alérgicas e de rejeição de órgãos ou tecidos transplantados |
| RU2233289C2 (ru) | 2002-11-04 | 2004-07-27 | Институт органического синтеза Уральского отделения РАН | Способ получения дипептидов |
-
2005
- 2005-03-25 RU RU2005108492/04A patent/RU2309144C2/ru active
-
2006
- 2006-03-24 JP JP2008502938A patent/JP5384096B2/ja not_active Expired - Fee Related
- 2006-03-24 CN CN200680017304.2A patent/CN101180267B/zh not_active Expired - Fee Related
- 2006-03-24 ES ES06733250.2T patent/ES2564238T3/es active Active
- 2006-03-24 UA UAA200711752A patent/UA88688C2/ru unknown
- 2006-03-24 MX MX2007011852A patent/MX2007011852A/es active IP Right Grant
- 2006-03-24 PL PL06733250T patent/PL1876169T3/pl unknown
- 2006-03-24 KR KR1020077024641A patent/KR101383580B1/ko not_active Expired - Fee Related
- 2006-03-24 PT PT67332502T patent/PT1876169E/pt unknown
- 2006-03-24 CA CA2602545A patent/CA2602545C/en not_active Expired - Fee Related
- 2006-03-24 HU HUE06733250A patent/HUE027009T2/en unknown
- 2006-03-24 DK DK06733250.2T patent/DK1876169T3/en active
- 2006-03-24 WO PCT/RU2006/000139 patent/WO2006101422A1/ru not_active Ceased
- 2006-03-24 EP EP06733250.2A patent/EP1876169B1/en not_active Not-in-force
- 2006-03-24 US US11/886,965 patent/US8309766B2/en not_active Expired - Fee Related
- 2006-03-24 SI SI200632027A patent/SI1876169T1/sl unknown
- 2006-03-24 EA EA200702072A patent/EA013644B1/ru not_active IP Right Cessation
-
2012
- 2012-11-12 US US13/674,339 patent/US8546612B2/en not_active Expired - Fee Related
-
2016
- 2016-03-10 CY CY20161100208T patent/CY1117449T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| HK1118798A1 (en) | 2009-02-20 |
| PT1876169E (pt) | 2016-03-21 |
| US20090111874A1 (en) | 2009-04-30 |
| MX2007011852A (es) | 2008-02-21 |
| US20130109880A1 (en) | 2013-05-02 |
| JP5384096B2 (ja) | 2014-01-08 |
| KR101383580B1 (ko) | 2014-04-09 |
| WO2006101422A1 (fr) | 2006-09-28 |
| CY1117449T1 (el) | 2017-04-26 |
| JP2008534495A (ja) | 2008-08-28 |
| CA2602545C (en) | 2014-08-19 |
| US8546612B2 (en) | 2013-10-01 |
| DK1876169T3 (en) | 2016-03-07 |
| RU2005108492A (ru) | 2006-10-10 |
| RU2309144C2 (ru) | 2007-10-27 |
| EA200702072A1 (ru) | 2008-02-28 |
| CN101180267A (zh) | 2008-05-14 |
| ES2564238T3 (es) | 2016-03-21 |
| SI1876169T1 (sl) | 2016-05-31 |
| CN101180267B (zh) | 2015-06-17 |
| HUE027009T2 (en) | 2016-10-28 |
| EP1876169A4 (en) | 2009-11-04 |
| PL1876169T3 (pl) | 2016-06-30 |
| KR20080008345A (ko) | 2008-01-23 |
| EA013644B1 (ru) | 2010-06-30 |
| CA2602545A1 (en) | 2006-09-28 |
| EP1876169B1 (en) | 2015-12-30 |
| EP1876169A1 (en) | 2008-01-09 |
| US8309766B2 (en) | 2012-11-13 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| UA88688C2 (ru) | Фенилсодержащие n-ацилные производные аминов и аминокислот, способ их получения, фармацевтическая композиция и их применение | |
| MY147994A (en) | Azabiphenylaminobenzoic acid derivatives as dhodh inhibitors | |
| MY149731A (en) | Compounds | |
| MX2010003866A (es) | Heteroaril amidas utiles como inhibidores de canales de sodio dependientes de voltaje. | |
| MX2010006799A (es) | Benzofuropirimidinonas como inhibidores de la proteina cinasa. | |
| MX2010003865A (es) | Aril amidas utiles como inhibidores de canales de sodio dependientes de voltaje. | |
| MX2008010884A (es) | Acidos 4-fenil-tiazol-5-carboxilicos y amidas de acidos 4-fenil-tiazol-5-carboxilicos como inhibidores de la plk1. | |
| WO2004113297A3 (en) | Aza-ring derivatives and their use as monoamine neurotransmitter re-uptake inhibitors | |
| MY143568A (en) | 11b-hsd1 inhibitors for the treatment of diabetes | |
| TW200510404A (en) | Novel 8-aza-bicyclo[3.2.1] octane derivatives and their use as monoamine neurotransmitter re-uptake inhibitors | |
| MX2010009147A (es) | Derivados de pirrolidinilo y usos de los mismos. | |
| TW200616958A (en) | New alkyl-pyridines as 11-beta inhibitors for diabetes | |
| MX2009005916A (es) | Nuevos derivados de cromen-2-ona y su uso como inhibidores de la reabsorcion del neurotransmisor de monoamina. | |
| PL1797088T3 (pl) | Nowe pochodne chromen-2-onu i ich zastosowanie jako inhibitorów wychwytu zwrotnego neurotransmiteru monoaminowego | |
| TW200800980A (en) | Novel compounds | |
| TW200604173A (en) | Novel compounds | |
| MX2010001075A (es) | Derivados de n-piperidin-4-ilmetil-amida y su uso como inhibidores de recaptacion del neurotransmisor de monoamina. | |
| MX2010004235A (es) | Piperidinas tri-sustituidas. | |
| UA94042C2 (ru) | Применение агомелатина в получении лекарственных средств, предназначенных для лечения синдрома смита-магениса | |
| DK1594868T3 (da) | 8-aza-bicyclo[3.2.1]octanderivater og anvendelse deraf som monoamin-neurotransmitter-genoptagelsesinhibitorer | |
| MX2009006213A (es) | Nuevos derivados de cromen-2-ona y su uso como inhibidores de reabsorcion del neurotransmisor monoamina. | |
| EA201000611A1 (ru) | 4,4-дизамещенные пиперидины | |
| PL375163A1 (en) | Novel piperidine derivatives and their use as monoamine neurotransmitter re-uptake inhibitors | |
| MX2008008470A (es) | Nuevos derivados pirrolicos con actividad inhibidora de desacetilasa de histonas. | |
| EA201000720A1 (ru) | 4,4-дизамещённые пиперидины как ингибиторы ренина |