PL1876169T3 - Pochodne amin n-acylowych i aminokwasów zawierające fenyl, sposoby ich wytwarzania, kompozycje farmaceutyczne i ich zastosowanie - Google Patents
Pochodne amin n-acylowych i aminokwasów zawierające fenyl, sposoby ich wytwarzania, kompozycje farmaceutyczne i ich zastosowanieInfo
- Publication number
- PL1876169T3 PL1876169T3 PL06733250T PL06733250T PL1876169T3 PL 1876169 T3 PL1876169 T3 PL 1876169T3 PL 06733250 T PL06733250 T PL 06733250T PL 06733250 T PL06733250 T PL 06733250T PL 1876169 T3 PL1876169 T3 PL 1876169T3
- Authority
- PL
- Poland
- Prior art keywords
- phenyl
- production
- methods
- pharmaceutical composition
- acyl amine
- Prior art date
Links
- 150000003862 amino acid derivatives Chemical class 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/12—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by halogen atoms or by nitro or nitroso groups
- C07C233/13—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by halogen atoms or by nitro or nitroso groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/02—Preparation of carboxylic acid amides from carboxylic acids or from esters, anhydrides, or halides thereof by reaction with ammonia or amines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/14—Preparation of carboxylic acid amides by formation of carboxamide groups together with reactions not involving the carboxamide groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/02—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
- C07C233/11—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals with carbon atoms of carboxamide groups bound to carbon atoms of an unsaturated carbon skeleton containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/16—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
- C07C233/17—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
- C07C233/22—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom having the carbon atom of the carboxamide group bound to an acyclic carbon atom of a carbon skeleton containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/45—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups
- C07C233/46—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
- C07C233/51—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom having the carbon atom of the carboxamide group bound to an acyclic carbon atom of a carbon skeleton containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
- C07C235/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
- C07C235/32—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
- C07C235/34—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
- C07C237/20—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
- C07C237/22—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton having nitrogen atoms of amino groups bound to the carbon skeleton of the acid part, further acylated
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Psychology (AREA)
- Psychiatry (AREA)
- Rheumatology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| RU2005108492/04A RU2309144C2 (ru) | 2005-03-25 | 2005-03-25 | Фенилсодержащие n-ацильные производные аминов, способ их получения, фармацевтическая композиция и их применение в качестве противовоспалительных и анальгетических средств |
| EP06733250.2A EP1876169B1 (en) | 2005-03-25 | 2006-03-24 | Phenyl-containing n-acyl amine and aminoacid derivatives, methods for the production thereof, a pharmaceutical composition and the use thereof |
| PCT/RU2006/000139 WO2006101422A1 (fr) | 2005-03-25 | 2006-03-24 | Derives n-acyles d'amines et d'acides amines amines contenant des phenyles, procede de fabrication, composition pharmaceutique et son utilisation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL1876169T3 true PL1876169T3 (pl) | 2016-06-30 |
Family
ID=37024023
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL06733250T PL1876169T3 (pl) | 2005-03-25 | 2006-03-24 | Pochodne amin n-acylowych i aminokwasów zawierające fenyl, sposoby ich wytwarzania, kompozycje farmaceutyczne i ich zastosowanie |
Country Status (18)
| Country | Link |
|---|---|
| US (2) | US8309766B2 (pl) |
| EP (1) | EP1876169B1 (pl) |
| JP (1) | JP5384096B2 (pl) |
| KR (1) | KR101383580B1 (pl) |
| CN (1) | CN101180267B (pl) |
| CA (1) | CA2602545C (pl) |
| CY (1) | CY1117449T1 (pl) |
| DK (1) | DK1876169T3 (pl) |
| EA (1) | EA013644B1 (pl) |
| ES (1) | ES2564238T3 (pl) |
| HU (1) | HUE027009T2 (pl) |
| MX (1) | MX2007011852A (pl) |
| PL (1) | PL1876169T3 (pl) |
| PT (1) | PT1876169E (pl) |
| RU (1) | RU2309144C2 (pl) |
| SI (1) | SI1876169T1 (pl) |
| UA (1) | UA88688C2 (pl) |
| WO (1) | WO2006101422A1 (pl) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK1546088T3 (en) | 2002-10-03 | 2015-03-30 | Novaremed Ltd | RELATIONSHIPS FOR USING THE TREATMENT OF AUTO-IMMUNE DISEASES, IMMUNOALLERGIC DISEASES AND ORGAN OR TISSUE TRANSPLANT AID |
| AU2005225239B2 (en) | 2002-10-03 | 2012-06-14 | Novaremed Ltd | Compounds for treating AIDS and other diseases |
| GB0804213D0 (en) * | 2008-03-06 | 2008-04-16 | New Era Biotech Ltd | A method of printing or preventing pain |
| MX2010008196A (es) * | 2008-04-29 | 2010-08-11 | Hoffmann La Roche | Derivados de acido 4-dimetilaminobutirico. |
| US8802734B2 (en) | 2009-09-09 | 2014-08-12 | Novaremed Limited | Method of treating or preventing pain |
| PT2475361T (pt) * | 2009-09-09 | 2020-02-10 | Novaremed Ltd | Derivados de benzenopropanamidas substituídas em n, para serem utilizadas no tratamento de dor e de inflamação |
| DK2617707T3 (da) * | 2010-08-27 | 2017-01-02 | Neopharm Co Ltd | Hidtil ukendt forbindelse, der fremmer sekretion af humanderiveret antimikrobielt peptid, fremgangsmåde til fremstilling af samme og sammensætning med samme som aktiv bestanddel |
| GB201116335D0 (en) * | 2011-09-21 | 2011-11-02 | Novaremed Ltd | A method of treating or preventing affective disorders |
| ES2578377B1 (es) | 2014-12-22 | 2017-05-04 | Consejo Superior De Investigaciones Científicas (Csic) | Compuestos moduladores del sensor neuronal de calcio dream y sus usos terapéuticos. |
| RU2690188C2 (ru) * | 2017-05-26 | 2019-05-31 | Общество С Ограниченной Ответственностью "Фарминтерпрайсез" | Новый мультитаргетный препарат для лечения заболеваний у млекопитающих |
| EP3672934A4 (en) * | 2017-08-21 | 2021-05-05 | Plex Pharmaceuticals, Inc. | DOUBLE ACTING FKBP12 AND FKBP52 INHIBITORS |
| RU2678563C1 (ru) * | 2017-10-27 | 2019-01-30 | Михаил Владимирович Овчинников | Водорастворимые производные тирозина, обладающие анальгетическим, противовоспалительным и противоотечным действием |
| RU2697414C1 (ru) * | 2018-05-11 | 2019-08-14 | Общество с ограниченной ответственностью "АЙ БИ ДИ Терапевтикс" | Новый антагонист тахикининовых рецепторов и его применение |
| RU2727703C2 (ru) * | 2018-10-29 | 2020-07-23 | Общество С Ограниченной Ответственностью "Фарминтерпрайсез" | Новый способ получения (S)-2-(2-(4-гидроксифенил)ацетамидо)-3-фенилпропановой кислоты |
| RU2716258C1 (ru) * | 2019-07-30 | 2020-03-11 | Автономная некоммерческая образовательная организация высшего образования Сколковский институт науки и технологий | Пептидный антагонист нмда-рецептора |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2711656A1 (de) * | 1977-03-17 | 1978-09-21 | Basf Ag | Neue pyridin-3-ole |
| EP0000252B1 (en) * | 1977-06-29 | 1982-02-03 | Beecham Group Plc | Peptides, pharmaceutical compositions containing the peptides and a process for the preparation of the peptides |
| JPS57145891A (en) * | 1981-03-05 | 1982-09-09 | Sagami Chem Res Center | Optically active diphosphine ligand |
| JPS57193437A (en) * | 1981-05-21 | 1982-11-27 | Ajinomoto Co Inc | Amino acid derivative |
| ES8607214A1 (es) * | 1985-10-16 | 1986-06-01 | Gema Sa | Procedimiento enzimatico de resolucion de n-fenilacetil-ami-nocompuestos y purificacion de sus isomeros opticamente ac- tivos |
| USRE37160E1 (en) * | 1990-06-12 | 2001-05-01 | Rutgers, The State University | Synthesis of tyrosine derived diphenol monomers |
| US5403851A (en) * | 1994-04-05 | 1995-04-04 | Interneuron Pharmaceuticals, Inc. | Substituted tryptamines, phenalkylamines and related compounds |
| AU1463997A (en) | 1995-12-22 | 1997-07-17 | Acea Pharmaceuticals, Inc. | Subtype-selective nmda receptor ligands and the use thereof |
| US6319492B1 (en) * | 1996-11-27 | 2001-11-20 | Rutgers, The State University | Copolymers of tyrosine-based polyarylates and poly(alkylene oxides) |
| US5912225A (en) * | 1997-04-14 | 1999-06-15 | Johns Hopkins Univ. School Of Medicine | Biodegradable poly (phosphoester-co-desaminotyrosyl L-tyrosine ester) compounds, compositions, articles and methods for making and using the same |
| JPH11127894A (ja) * | 1997-10-30 | 1999-05-18 | Ono Pharmaceut Co Ltd | カルボキシペプチダーゼａ活性測定方法および測定用キット |
| RU2123041C1 (ru) * | 1998-04-02 | 1998-12-10 | Пипия Гулади Эрастович | Бальзам "саратовский" |
| US20020151668A1 (en) * | 1998-04-13 | 2002-10-17 | Ken James | Construction of copolymer libraries |
| WO1999055330A1 (en) * | 1998-04-27 | 1999-11-04 | Smithkline Beecham Corporation | Ccr-3 receptor antagonists |
| US6414173B1 (en) * | 1998-07-02 | 2002-07-02 | University Of Maryland | Hypervalent silane and siloxane derivatives and the use thereof |
| US6852856B2 (en) * | 2000-03-09 | 2005-02-08 | Tokuyama Corporation | Method for preserving quaternary ammonium salt |
| AU9631301A (en) * | 2000-09-27 | 2002-04-08 | Procter & Gamble | Melanocortin receptor ligands |
| DK1546088T3 (en) * | 2002-10-03 | 2015-03-30 | Novaremed Ltd | RELATIONSHIPS FOR USING THE TREATMENT OF AUTO-IMMUNE DISEASES, IMMUNOALLERGIC DISEASES AND ORGAN OR TISSUE TRANSPLANT AID |
| RU2233289C2 (ru) * | 2002-11-04 | 2004-07-27 | Институт органического синтеза Уральского отделения РАН | Способ получения дипептидов |
-
2005
- 2005-03-25 RU RU2005108492/04A patent/RU2309144C2/ru active
-
2006
- 2006-03-24 EA EA200702072A patent/EA013644B1/ru not_active IP Right Cessation
- 2006-03-24 JP JP2008502938A patent/JP5384096B2/ja not_active Expired - Fee Related
- 2006-03-24 WO PCT/RU2006/000139 patent/WO2006101422A1/ru not_active Ceased
- 2006-03-24 PL PL06733250T patent/PL1876169T3/pl unknown
- 2006-03-24 UA UAA200711752A patent/UA88688C2/ru unknown
- 2006-03-24 DK DK06733250.2T patent/DK1876169T3/en active
- 2006-03-24 KR KR1020077024641A patent/KR101383580B1/ko not_active Expired - Fee Related
- 2006-03-24 EP EP06733250.2A patent/EP1876169B1/en not_active Not-in-force
- 2006-03-24 ES ES06733250.2T patent/ES2564238T3/es active Active
- 2006-03-24 CA CA2602545A patent/CA2602545C/en not_active Expired - Fee Related
- 2006-03-24 PT PT67332502T patent/PT1876169E/pt unknown
- 2006-03-24 US US11/886,965 patent/US8309766B2/en not_active Expired - Fee Related
- 2006-03-24 CN CN200680017304.2A patent/CN101180267B/zh not_active Expired - Fee Related
- 2006-03-24 SI SI200632027A patent/SI1876169T1/sl unknown
- 2006-03-24 MX MX2007011852A patent/MX2007011852A/es active IP Right Grant
- 2006-03-24 HU HUE06733250A patent/HUE027009T2/en unknown
-
2012
- 2012-11-12 US US13/674,339 patent/US8546612B2/en not_active Expired - Fee Related
-
2016
- 2016-03-10 CY CY20161100208T patent/CY1117449T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| SI1876169T1 (sl) | 2016-05-31 |
| KR101383580B1 (ko) | 2014-04-09 |
| JP5384096B2 (ja) | 2014-01-08 |
| US8309766B2 (en) | 2012-11-13 |
| WO2006101422A1 (fr) | 2006-09-28 |
| HK1118798A1 (en) | 2009-02-20 |
| EA013644B1 (ru) | 2010-06-30 |
| RU2005108492A (ru) | 2006-10-10 |
| DK1876169T3 (en) | 2016-03-07 |
| CN101180267A (zh) | 2008-05-14 |
| CY1117449T1 (el) | 2017-04-26 |
| EP1876169A4 (en) | 2009-11-04 |
| PT1876169E (pt) | 2016-03-21 |
| MX2007011852A (es) | 2008-02-21 |
| JP2008534495A (ja) | 2008-08-28 |
| CA2602545A1 (en) | 2006-09-28 |
| CN101180267B (zh) | 2015-06-17 |
| US20090111874A1 (en) | 2009-04-30 |
| UA88688C2 (ru) | 2009-11-10 |
| US20130109880A1 (en) | 2013-05-02 |
| RU2309144C2 (ru) | 2007-10-27 |
| US8546612B2 (en) | 2013-10-01 |
| ES2564238T3 (es) | 2016-03-21 |
| CA2602545C (en) | 2014-08-19 |
| EP1876169B1 (en) | 2015-12-30 |
| KR20080008345A (ko) | 2008-01-23 |
| EA200702072A1 (ru) | 2008-02-28 |
| EP1876169A1 (en) | 2008-01-09 |
| HUE027009T2 (en) | 2016-10-28 |
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