UA85196C2 - Способ получения сульфоксида в виде отдельного энантиомера или энантиомерно обогащенной формы - Google Patents

Способ получения сульфоксида в виде отдельного энантиомера или энантиомерно обогащенной формы

Info

Publication number
UA85196C2
UA85196C2 UAA200604415A UAA200604415A UA85196C2 UA 85196 C2 UA85196 C2 UA 85196C2 UA A200604415 A UAA200604415 A UA A200604415A UA A200604415 A UAA200604415 A UA A200604415A UA 85196 C2 UA85196 C2 UA 85196C2
Authority
UA
Ukraine
Prior art keywords
preparing
sulphide
single enantiomer
enantiomerically enriched
enriched form
Prior art date
Application number
UAA200604415A
Other languages
English (en)
Ukrainian (uk)
Inventor
Франсуа Рибьер
Жерар Дюре
Лоранс Пра
Original Assignee
Сефалон Франс
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Сефалон Франс filed Critical Сефалон Франс
Publication of UA85196C2 publication Critical patent/UA85196C2/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C315/00—Preparation of sulfones; Preparation of sulfoxides
    • C07C315/04—Preparation of sulfones; Preparation of sulfoxides by reactions not involving the formation of sulfone or sulfoxide groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C315/00—Preparation of sulfones; Preparation of sulfoxides
    • C07C315/02—Preparation of sulfones; Preparation of sulfoxides by formation of sulfone or sulfoxide groups by oxidation of sulfides, or by formation of sulfone groups by oxidation of sulfoxides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • C07C317/44—Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Catalysts (AREA)
UAA200604415A 2003-09-19 2004-09-17 Способ получения сульфоксида в виде отдельного энантиомера или энантиомерно обогащенной формы UA85196C2 (ru)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP03292312A EP1516869A1 (en) 2003-09-19 2003-09-19 Process for enantioselective synthesis of single enantiomers of modafinil by asymmetric oxidation

Publications (1)

Publication Number Publication Date
UA85196C2 true UA85196C2 (ru) 2009-01-12

Family

ID=34178643

Family Applications (1)

Application Number Title Priority Date Filing Date
UAA200604415A UA85196C2 (ru) 2003-09-19 2004-09-17 Способ получения сульфоксида в виде отдельного энантиомера или энантиомерно обогащенной формы

Country Status (21)

Country Link
US (2) US7317126B2 (ru)
EP (2) EP1516869A1 (ru)
JP (1) JP4713480B2 (ru)
KR (1) KR101136703B1 (ru)
CN (1) CN100404502C (ru)
AT (1) ATE365711T1 (ru)
AU (1) AU2004274248B2 (ru)
BR (1) BRPI0414298B1 (ru)
CA (1) CA2538697C (ru)
DE (1) DE602004007278T2 (ru)
DK (1) DK1663963T3 (ru)
EA (1) EA009385B1 (ru)
ES (1) ES2289556T3 (ru)
MX (1) MXPA06002935A (ru)
NZ (1) NZ545739A (ru)
PL (1) PL1663963T3 (ru)
PT (1) PT1663963E (ru)
SI (1) SI1663963T1 (ru)
UA (1) UA85196C2 (ru)
WO (1) WO2005028428A1 (ru)
ZA (1) ZA200601962B (ru)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1516869A1 (en) * 2003-09-19 2005-03-23 Cephalon France Process for enantioselective synthesis of single enantiomers of modafinil by asymmetric oxidation
US7368591B2 (en) 2003-09-19 2008-05-06 Cephalon France Process for enantioselective synthesis of single enantiomers of modafinil by asymmetric oxidation
EP1702915A1 (en) * 2005-03-14 2006-09-20 Cephalon France Process for enantioselective synthesis of single enantiomers of thio-substituted arylmethanesulfinyl derivatives by asymmetric oxidation
CN1321978C (zh) * 2005-04-29 2007-06-20 浙江工业大学 一种2－（二苯基甲基亚硫酰基）乙酰胺的合成方法
WO2007027328A2 (en) * 2005-07-28 2007-03-08 University Of Iowa Research Foundation Microbial sulfoxidation and amidation of benzhdrylsulfanyl carboxylic acids and uses thereof
JP2009508880A (ja) * 2006-02-21 2009-03-05 テバ ファーマシューティカル インダストリーズ リミティド アルモダフィニルの新規な結晶形とその調製方法
US20080031939A1 (en) 2006-03-01 2008-02-07 Viviana Braude Process for the preparation of armodafinil
US20080214862A1 (en) * 2006-12-06 2008-09-04 Ben-Zion Dolitzky Processes for preparing armodafinil intermediate
AU2008259588A1 (en) * 2007-06-04 2008-12-11 Generics [Uk] Limited Novel process
WO2009024863A2 (en) * 2007-06-26 2009-02-26 Actavis Group Ptc Ehf Process for the preparation of modafinil enantiomers
US7960586B2 (en) * 2007-08-16 2011-06-14 Teva Pharmaceutical Industries Ltd. Purification of armodafinil
CN102471290B (zh) 2009-07-16 2016-02-03 拜耳知识产权有限责任公司 手性3-三唑基亚砜衍生物的制备方法
BR112012016799A2 (pt) * 2010-01-07 2019-10-08 Vivus Inc tratamento da síndrome de apneia obstrutiva do sono com uma combinação de um inibidor da anidrase carbônica e um agente ativo adicional
RU2448954C1 (ru) * 2010-10-18 2012-04-27 Учреждение Российской академии наук Институт катализа им. Г.К. Борескова Сибирского отделения РАН Способ получения сульфоксидов
EP2649187B1 (en) 2010-12-08 2017-11-22 Codexis, Inc. Biocatalysts and methods for the synthesis of armodafinil
FR2970711B1 (fr) * 2011-01-20 2016-03-04 Hopitaux Paris Assist Publique La lauflumide et ses enantiomeres, preparation et utilisations therapeutiques
RU2477316C1 (ru) * 2011-12-29 2013-03-10 Учреждение Российской академии наук Институт экологии и генетики микроорганизмов Уральского отделения РАН Биокаталитический способ получения (r)-фенилметилового сульфоксида
CN104447440B (zh) * 2013-09-12 2016-05-18 中国科学院大连化学物理研究所 一种催化不对称氧化硫醚的方法
CN104045588A (zh) * 2014-06-11 2014-09-17 江苏斯威森生物医药工程研究中心有限公司 一种2-(4,4’-二卤-二苯基甲基亚磺酰)乙酰胺的合成方法
EP2985279B1 (en) 2014-08-13 2017-08-02 Red Bull GmbH Heterocyclic compounds with working memory enhancing activity
WO2016023997A1 (en) 2014-08-13 2016-02-18 Red Bull Gmbh Heterocyclic compounds with working memory enhancing activity
US9616068B2 (en) 2014-10-27 2017-04-11 Pohela LLC Animal training using cognitive enhancement
CN110746428A (zh) * 2019-10-29 2020-02-04 株洲千金药业股份有限公司 一种r型手性亚砜类化合物的制备方法
CN110698482A (zh) * 2019-10-29 2020-01-17 株洲千金药业股份有限公司 一种s型手性亚砜类化合物的制备方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4127722A (en) * 1975-10-02 1978-11-28 Laboratoire L. Lafon Benzhydrylsulphinyl derivatives
GB1584462A (en) * 1977-03-31 1981-02-11 Lafon Labor N-diaryl-malonamide and diarylmethyl-sulphinyl-acetamide derivatives and pharmaceutical compositions containing them
FR2528038B2 (fr) * 1982-06-04 1985-08-09 Lafon Labor Derives de benzhydrylsulfinylacetamide et leur utilisation en therapeutique
FR2593809B1 (fr) * 1986-01-31 1988-07-22 Lafon Labor Benzhydrylsulfinylacetamide, procede de preparation et utilisation en therapeutique
CA2416792C (en) * 2000-07-27 2010-02-09 Teva Pharmaceutical Industries Ltd. Crystalline and pure modafinil, and process of preparing the same
IL143106A (en) * 2001-05-13 2005-11-20 Chemagis Ltd Process for the preparation of diphenylmethylthioacetamide
US20040048931A1 (en) 2002-07-12 2004-03-11 Craig Heacock Modafinil pharmaceutical compositions
FR2849029B1 (fr) 2002-12-20 2005-03-18 Lafon Labor Procede de preparation et formes cristallines des enantiomeres optiques du modafinil.
EP1437345A1 (en) 2003-01-13 2004-07-14 Organisation de Synthese Mondiale Orsymonde Novel method for preparing methyl 2-diphenylmethylsulfinylacetate
EP1516869A1 (en) * 2003-09-19 2005-03-23 Cephalon France Process for enantioselective synthesis of single enantiomers of modafinil by asymmetric oxidation

Also Published As

Publication number Publication date
US20050080256A1 (en) 2005-04-14
EP1663963B1 (en) 2007-06-27
KR20070009968A (ko) 2007-01-19
DK1663963T3 (da) 2007-10-29
EA200600593A1 (ru) 2006-08-25
PL1663963T3 (pl) 2007-11-30
JP2007505891A (ja) 2007-03-15
EP1663963A1 (en) 2006-06-07
DE602004007278D1 (de) 2007-08-09
NZ545739A (en) 2010-01-29
CA2538697A1 (en) 2005-03-31
BRPI0414298B1 (pt) 2021-06-08
ZA200601962B (en) 2007-06-27
US20080171896A1 (en) 2008-07-17
CN100404502C (zh) 2008-07-23
WO2005028428A1 (en) 2005-03-31
CN1867544A (zh) 2006-11-22
MXPA06002935A (es) 2006-06-14
SI1663963T1 (sl) 2007-12-31
EA009385B1 (ru) 2007-12-28
AU2004274248B2 (en) 2010-08-26
EP1516869A1 (en) 2005-03-23
US7317126B2 (en) 2008-01-08
ATE365711T1 (de) 2007-07-15
CA2538697C (en) 2012-11-13
JP4713480B2 (ja) 2011-06-29
BRPI0414298A (pt) 2006-11-14
US7812193B2 (en) 2010-10-12
PT1663963E (pt) 2007-10-19
KR101136703B1 (ko) 2012-05-24
ES2289556T3 (es) 2008-02-01
AU2004274248A1 (en) 2005-03-31
DE602004007278T2 (de) 2008-02-28

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