UA77660C2 - Compositions and methods for reducing plasma lipoprotein a level in human - Google Patents
Compositions and methods for reducing plasma lipoprotein a level in human Download PDFInfo
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- UA77660C2 UA77660C2 UA2003043902A UA2003043902A UA77660C2 UA 77660 C2 UA77660 C2 UA 77660C2 UA 2003043902 A UA2003043902 A UA 2003043902A UA 2003043902 A UA2003043902 A UA 2003043902A UA 77660 C2 UA77660 C2 UA 77660C2
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- composition
- lipoprotein
- plasma
- mammal
- cholesterol
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Classifications
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
- A61K31/375—Ascorbic acid, i.e. vitamin C; Salts thereof
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/401—Proline; Derivatives thereof, e.g. captopril
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/455—Nicotinic acids, e.g. niacin; Derivatives thereof, e.g. esters, amides
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
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- General Chemical & Material Sciences (AREA)
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- Cardiology (AREA)
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- Obesity (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines Containing Plant Substances (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US23718600P | 2000-10-03 | 2000-10-03 | |
| PCT/US2001/031203 WO2002028379A2 (en) | 2000-10-03 | 2001-10-03 | Compositions and methods for lowering plasma lipoprotein(a) and risk factors of cardiovascular diseases |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| UA77660C2 true UA77660C2 (en) | 2007-01-15 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UA2003043902A UA77660C2 (en) | 2000-10-03 | 2001-03-10 | Compositions and methods for reducing plasma lipoprotein a level in human |
Country Status (24)
| Country | Link |
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| US (2) | US6693129B2 (cs) |
| EP (1) | EP1324753A2 (cs) |
| JP (1) | JP2004525080A (cs) |
| KR (1) | KR20030070003A (cs) |
| CN (1) | CN100421659C (cs) |
| AU (2) | AU1145202A (cs) |
| BR (1) | BR0114526A (cs) |
| CA (1) | CA2424880A1 (cs) |
| CZ (1) | CZ20031167A3 (cs) |
| EE (1) | EE200300136A (cs) |
| HR (1) | HRP20030348A2 (cs) |
| HU (1) | HUP0303040A3 (cs) |
| IL (2) | IL155238A0 (cs) |
| MX (1) | MXPA03002964A (cs) |
| NO (1) | NO20031510L (cs) |
| NZ (2) | NZ525390A (cs) |
| PL (1) | PL212479B1 (cs) |
| RO (1) | RO120567B1 (cs) |
| RU (1) | RU2289406C2 (cs) |
| SK (1) | SK5252003A3 (cs) |
| TR (1) | TR200300594T2 (cs) |
| UA (1) | UA77660C2 (cs) |
| WO (1) | WO2002028379A2 (cs) |
| ZA (1) | ZA200302772B (cs) |
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| AU2002221131A1 (en) * | 2000-12-14 | 2002-06-24 | Sankyo Company Limited | Blood lipid ameliorant composition |
| PT1397148E (pt) * | 2001-02-27 | 2006-11-30 | Nutrition 21 Inc | Tratamento da dislipidemia com crómio/biotina |
| US20030054978A1 (en) * | 2001-08-31 | 2003-03-20 | Babish John G. | Arginine compositions for coordinate modification of multiple cardiovascular risk factors |
| US20040097467A1 (en) * | 2002-08-22 | 2004-05-20 | Vijaya Juturu | Arginine silicate inositol complex and use thereof |
| US7635469B2 (en) * | 2002-08-28 | 2009-12-22 | Premier Micronutrient Corporation | Micronutrient formulations for hearing health |
| US20080020035A1 (en) * | 2002-08-28 | 2008-01-24 | Kedar Prasad | Micronutrient formulations and related methods of manufacture |
| US20080145424A1 (en) * | 2002-10-24 | 2008-06-19 | Enos Phramaceuticals, Inc. | Sustained release L-arginine formulations and methods of manufacture and use |
| KR20050083827A (ko) * | 2002-10-24 | 2005-08-26 | 이노스 파마슈티칼스, 인코포레이티드 | 서방성 ｌ-아르기닌 포뮬레이션 및 이의 제조방법 및 용도 |
| US20050053673A1 (en) * | 2003-09-05 | 2005-03-10 | Shrirang Netke | Composition and method for facilitating bone healing |
| CA2540202A1 (en) * | 2003-09-29 | 2005-04-21 | Enos Pharmaceuticals, Inc. | Sustained release l-arginine formulations and methods of manufacture and use |
| US20050074443A1 (en) * | 2003-10-03 | 2005-04-07 | Treadwell Benjamin V. | Methods of attenuating autoimmune disease and compositions useful therefor |
| JP2005187454A (ja) * | 2003-12-05 | 2005-07-14 | Sankyo Co Ltd | ビタミンｅ含有ｌｄｌ低下剤及び／又は動脈硬化抑制剤組成物 |
| JP2005225871A (ja) * | 2004-01-16 | 2005-08-25 | Sankyo Co Ltd | 血中トリグリセライド又はホモシステインを低下させる医薬組成物 |
| US20080032952A1 (en) * | 2004-07-09 | 2008-02-07 | Marjorie Zettler | Combination Therapies Employing Nicotinic Acid Derivatives or Fibric Acid Derivatives |
| JP4896531B2 (ja) * | 2005-01-25 | 2012-03-14 | 第一三共ヘルスケア株式会社 | 血中ＣｏＱ１０量を増加させる医薬組成物 |
| US7628984B2 (en) * | 2005-02-17 | 2009-12-08 | Premier Micronutrient Corporation | Micronutrient formulations for pulmonary and heart health |
| US7887852B2 (en) * | 2005-06-03 | 2011-02-15 | Soft Gel Technologies, Inc. | Soft gel capsules containing polymethoxylated flavones and palm oil tocotrienols |
| US20070072910A1 (en) * | 2005-09-29 | 2007-03-29 | Smith Michael L | Compositions and methods for lowering plasma concentrations of low density lipoproteins in humans |
| KR100592719B1 (ko) * | 2005-10-05 | 2006-06-28 | 케이에스엠기술 주식회사 | 하천의 생태계 보호용 이물질 유입방지 시설 |
| US20070292493A1 (en) * | 2006-06-15 | 2007-12-20 | Brierre Barbara T | Pharmaceutical composition and method for the transdermal delivery of calcium |
| US20080207748A1 (en) * | 2007-02-22 | 2008-08-28 | Innovation Labs, Inc. | Vitamin c preparation |
| EP3050568B1 (en) | 2007-03-13 | 2020-12-02 | JDS Therapeutics, LLC | Methods and compositions for the sustained release of chromium |
| WO2008139314A1 (en) * | 2007-05-11 | 2008-11-20 | Horphag Research (Luxembourg) Holding Sa | Compositions and methods for treating joint disorders |
| US7867524B2 (en) * | 2007-10-05 | 2011-01-11 | David Rowland | Energizing formulation |
| RU2377007C1 (ru) * | 2008-06-23 | 2009-12-27 | Открытое Акционерное Общество "Инвестиционная Финансовая Группа "Гленик-М" | Средство для лечения и профилактики онкологических заболеваний и способ применения этого средства (варианты) |
| RU2385722C1 (ru) * | 2008-07-02 | 2010-04-10 | Тимофей Георгиевич Кожока | Фармацевтическая нейропротекторная, антиоксидантная, антигипоксантная, антиапоптотическая и мембранопротекторная композиция и способ лечения |
| US20110091618A1 (en) * | 2009-10-16 | 2011-04-21 | Frito-Lay North America, Inc. | Method for preventing oxidation and off flavors in high carotenoid foods |
| RU2468791C2 (ru) * | 2011-02-24 | 2012-12-10 | Общество с ограниченной ответственностью "ДИНАМИК ДЕВЕЛОПМЕНТ ЛАБОРАТОРИЗ" | Композиция, обладающая адаптогенным, общеукрепляющим и повышающим работоспособность действием |
| EA025844B1 (ru) * | 2012-05-08 | 2017-02-28 | Общество С Ограниченной Ответственностью "Лигур-М" | Средство для коррекции гиперхолестеринемии |
| WO2015199537A1 (en) * | 2014-06-24 | 2015-12-30 | Dedraf Holding B.V. | New mineral composition |
| US10499682B2 (en) | 2014-08-25 | 2019-12-10 | New Age Beverage Corporation | Micronutrient formulation in electronic cigarettes |
| US11191735B2 (en) | 2015-03-13 | 2021-12-07 | Nutrition 21, Llc | Arginine silicate for periodontal disease |
| US20170135969A1 (en) | 2015-11-12 | 2017-05-18 | Jds Therapeutics, Llc | Topical arginine-silicate-inositol for wound healing |
| CA3014308A1 (en) | 2016-02-11 | 2017-08-17 | Nutrition 21, Llc | Chromium containing compositions for improving health and fitness |
| CN106213522A (zh) * | 2016-08-05 | 2016-12-14 | 郑家福 | 营养保健品 |
| US11357250B2 (en) | 2016-08-15 | 2022-06-14 | Summit Innovation Labs LLC | Treatment and prevention of diabetes and obesity |
| US11344575B2 (en) * | 2016-08-15 | 2022-05-31 | Summit Innovation Labs, LLC | Vascular calcification prevention and treatment |
| GB2568849B (en) | 2016-09-01 | 2022-08-10 | Nutrition 21 Llc | Magnesium biotinate compositions and methods of use |
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| CN108033939B (zh) * | 2017-12-26 | 2020-09-11 | 上海共晶医药科技有限公司 | 生育酚与脯氨酸的共结晶及其制备方法 |
| CN109092262B (zh) * | 2018-08-28 | 2019-07-05 | 广州达济医学科技有限公司 | 低密度脂蛋白吸附微球及制备方法和吸附材料 |
| JP2022515314A (ja) | 2018-11-02 | 2022-02-18 | ニュートリション・２１，エルエルシー | イノシトール安定化アルギニンケイ酸塩複合体及びイノシトールを含有するビデオゲームプレーヤーの認知機能を改善するための組成物 |
| WO2020139698A1 (en) * | 2018-12-26 | 2020-07-02 | Colgate-Palmolive Company | Specific co-aggregation inhibition by arginine |
| GB2613672A (en) | 2019-12-16 | 2023-06-14 | Nutrition 21 Llc | Methods of production of aginine-silicate complexes |
| CN119522095A (zh) | 2022-07-01 | 2025-02-25 | N·V·努特里奇亚 | 用于神经退行性病变和神经创伤的营养组合物 |
| IT202300020718A1 (it) * | 2023-10-06 | 2025-04-06 | Promin Prod Di Medicina Integrata S R L | Composizione a base di inositolo e proantocianidine oligomeriche |
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| US5278189A (en) * | 1990-06-04 | 1994-01-11 | Rath Matthias W | Prevention and treatment of occlusive cardiovascular disease with ascorbate and substances that inhibit the binding of lipoprotein (A) |
| US5650418A (en) * | 1990-06-04 | 1997-07-22 | Therapy 2000 | Therapeutic lysine salt composition and method of use |
| US5230996A (en) * | 1990-06-04 | 1993-07-27 | Therapy 2000 | Use of ascorbate and tranexamic acid solution for organ and blood vessel treatment prior to transplantation |
| US5308627A (en) * | 1990-08-07 | 1994-05-03 | Umbdenstock Jr Anthony J | Nutritional supplement for optimizing cellular health |
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| US5108767A (en) * | 1991-06-10 | 1992-04-28 | Abbott Laboratories | Liquid nutritional product for persons receiving renal dialysis |
| GB2268871A (en) * | 1992-07-04 | 1994-01-26 | Bio Nutritional Health Service | Composition for use as a food or food supplement |
| US5326569A (en) * | 1992-12-23 | 1994-07-05 | Abbott Laboratories | Medical foods for the nutritional support of child/adult metabolic diseases |
| US5962517A (en) * | 1997-01-31 | 1999-10-05 | Murad; Howard | Pharmaceutical compositions and methods for treating acne |
| US5922766A (en) * | 1997-07-02 | 1999-07-13 | Acosta; Phyllis J. B. | Palatable elemental medical food |
| EP1068868A3 (en) * | 1997-07-08 | 2001-01-31 | Rath, Matthias, Dr. med. | Synergistic compositions comprising ascorbate and lysine for states related to extracellular matrix degeneration |
| EP0891771A1 (en) * | 1997-07-08 | 1999-01-20 | Health Now, Inc. | Compositions comprising lysine and ascorbate compounds for the treatment and prevention of cardiovascular diseases |
| US6048846A (en) * | 1998-02-26 | 2000-04-11 | Cochran; Timothy M. | Compositions used in human treatment |
| US6299896B1 (en) * | 2000-04-13 | 2001-10-09 | Cooper Concepts, Inc. | Multi-vitamin and mineral supplement |
| US6361800B1 (en) * | 2000-04-13 | 2002-03-26 | Cooper Concepts, Inc. | Multi-vitamin and mineral supplement |
| EP1163904B1 (en) * | 2000-06-16 | 2006-04-19 | Rath, Matthias, Dr. med. | Composition for the prevention of smooth muscle diseases comprising ascorbate, arginine and magnesium |
| DE60028376T2 (de) * | 2000-10-09 | 2007-06-06 | Rath, Matthias, Dr. | Therapeutische Kombination des Ascorbats mit Lysin und Arginin für Verhinderung und Behandlung des Krebses |
| US6974833B2 (en) * | 2001-01-16 | 2005-12-13 | Matthias Rath | Synergistic compositions comprising ascobate and lysine for states related to extra cellular matrix degeneration |
| UA76444C2 (en) * | 2001-02-14 | 2006-08-15 | Composition of biochemical compounds involved in bioenergy metabolism of cells and method of its use in prevention and therapy of diseases | |
| US6686340B2 (en) * | 2001-06-19 | 2004-02-03 | Matthias Rath | Composition and method for prevention and treatment of health conditions caused by constriction of smooth muscle cells |
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