UA76960C2 - Method of analgesia - Google Patents
Method of analgesia Download PDFInfo
- Publication number
- UA76960C2 UA76960C2 UA2003032528A UA2003032528A UA76960C2 UA 76960 C2 UA76960 C2 UA 76960C2 UA 2003032528 A UA2003032528 A UA 2003032528A UA 2003032528 A UA2003032528 A UA 2003032528A UA 76960 C2 UA76960 C2 UA 76960C2
- Authority
- UA
- Ukraine
- Prior art keywords
- pain
- tetrodotoxin
- cancer
- ttx
- dose
- Prior art date
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| PCT/CN2001/001391 WO2002022129A1 (en) | 2000-09-18 | 2001-09-11 | A method of analgesia |
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| UA76960C2 true UA76960C2 (en) | 2006-10-16 |
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| EP (3) | EP2298306B1 (xx) |
| JP (1) | JP2004508404A (xx) |
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| CN (1) | CN1284536C (xx) |
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| BG (1) | BG107690A (xx) |
| BR (1) | BR0113961A (xx) |
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| IL (1) | IL154342A0 (xx) |
| IS (1) | IS6719A (xx) |
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| UA (1) | UA76960C2 (xx) |
| WO (1) | WO2002022129A1 (xx) |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2778455C2 (ru) * | 2017-03-29 | 2022-08-19 | Сайтван Терапевтикс, Инк. | 11,13-модифицированные сакситоксины для лечения боли |
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| US7119062B1 (en) | 2001-02-23 | 2006-10-10 | Neucoll, Inc. | Methods and compositions for improved articular surgery using collagen |
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| CN1203860C (zh) * | 2001-06-22 | 2005-06-01 | 威克斯医药有限公司 | 钠离子通道阻断剂和阿司匹林在制备用于对哺乳动物进行协同镇痛的药物中的应用 |
| US20030100574A1 (en) | 2001-11-15 | 2003-05-29 | Wilson Nestor Antonio Lagos | Use and application of a pharmaceutical composition containing a mixture of natural-origin heterocyclical guanidine, for cosmetology, wound healing, focal dystonia and muscular spasm-related clinical pathologies |
| WO2004013637A1 (en) * | 2002-08-01 | 2004-02-12 | Bayer Healthcare Ag | Diagnostics and therapeutics for diseases associated with g-protein coupled receptor 37 (gpr37) |
| AU2004207010A1 (en) * | 2003-01-30 | 2004-08-12 | Dynogen Pharmaceuticals, Inc. | Methods of treating lower urinary tract disorders using sodium channel modulators |
| CN1568999A (zh) * | 2003-07-14 | 2005-01-26 | 南宁枫叶药业有限公司 | 稳定的医药用河豚毒素冷冻干燥制剂 |
| JP2005154368A (ja) * | 2003-11-27 | 2005-06-16 | Teikoku Seiyaku Co Ltd | ジソピラミド含有神経因性疼痛の鎮痛剤 |
| CN1997373B (zh) * | 2004-05-07 | 2010-12-22 | 菲特托克斯有限公司 | 藻毒素及其用途 |
| JP2007538010A (ja) * | 2004-05-07 | 2007-12-27 | ファイトトックス リミテッド | フィコトキシンの経皮投与 |
| US20050282836A1 (en) * | 2004-06-22 | 2005-12-22 | Weiyang Lin | Solid orally ingestible formulations of tetrodotoxin |
| US20060034823A1 (en) * | 2004-08-13 | 2006-02-16 | Paul Reid | Method of production and use of crotoxin as an analgesic |
| CN100363006C (zh) * | 2004-08-20 | 2008-01-23 | 厦门朝阳生物工程有限公司 | 一种戒毒制剂及其制备方法 |
| EP1799219A1 (en) * | 2004-09-21 | 2007-06-27 | Laboratorios del Dr. Esteve S.A. | Tetrodotoxin and its derivatives for the treatment of central-nervously derived neuropathic pain |
| US20100075992A1 (en) * | 2004-09-22 | 2010-03-25 | Laboratorios Del Dr. Esteve S.A. | Tetrodotoxin and its derivatives for the treament of peripheral-nervously derived neuropathi pain |
| EP1690541A1 (en) * | 2005-02-11 | 2006-08-16 | Laboratorios Del Dr. Esteve, S.A. | Use of a sodium channel blocker and their analogues for the treatment of nicotine dependency |
| TW200640463A (en) * | 2005-02-11 | 2006-12-01 | Esteve Labor Dr | Use of sodium channel blockers and their analogues for the treatment of nicotine dependency |
| EP1714655A1 (en) * | 2005-04-22 | 2006-10-25 | Laboratorios Del Dr. Esteve, S.A. | Use of sodium channel blockers and their analogues for the treatment of nicotine dependency |
| EP1702627A1 (en) * | 2005-03-18 | 2006-09-20 | Laboratorios Del Dr. Esteve, S.A. | Analgesic combination of sodium channel blockers with opioid antagonists |
| EP1931349A4 (en) * | 2005-08-25 | 2009-08-05 | Wex Pharmaceuticals Inc | USE OF SODIUM CHANNEL BLOCKERS TO TREAT MUSCULO-SKELETAL PAIN |
| EP1928452A4 (en) * | 2005-08-25 | 2010-09-01 | Wex Medical Ltd | USE OF SODIUM CHANNEL BLOCKS FOR THE TREATMENT OF VISCERAL PAIN OR PAIN THROUGH CANCER TREATMENT |
| US20070148159A1 (en) * | 2005-12-22 | 2007-06-28 | Reid Paul F | Use of crotoxin as an analgesic - CIP |
| GB0603008D0 (en) * | 2006-02-14 | 2006-03-29 | Portela & Ca Sa | Method |
| EP1844781A1 (en) | 2006-02-22 | 2007-10-17 | Wex Pharmaceuticals Inc. | Use of sodium channel blockers for the treatment of preterm labor |
| EP2394646B1 (en) | 2006-03-27 | 2018-07-25 | Wex Medical Limited | Use of sodium channel blockers for the treatment of neuropathic pain developing as a consequence of chemotherapy |
| WO2007110220A1 (en) * | 2006-03-27 | 2007-10-04 | Wex Pharmaceuticals Inc. | USE OF 4,9-ANHYDRO-TETRODOTOXIN FOR THE TREATMENT OF DISEASES RELATED TO THE VOLTAGE-GATED SODIUM CHANNEL α SUBUNIT NAV 1.6 |
| EP1844782A1 (en) * | 2006-03-27 | 2007-10-17 | Wex Pharmaceuticals, Inc | Use of 4,9-anhydro-tetrodotoxin for the treatment of diseases related to the voltage-gated sodium channel subunit Nav1.6 |
| EP1844783A1 (en) * | 2006-03-27 | 2007-10-17 | Wex Pharmaceuticals, Inc | Use of 4,9-anhydro-tetrodotoxin for the treatment of diseases related to the voltage-gated sodium channel - subunit Nav1.6 |
| CN100438873C (zh) * | 2006-06-26 | 2008-12-03 | 黄致强 | 将河鲀毒素作为镇痛药的耐受抑制剂在制备复方镇痛制剂中的应用 |
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| US8952152B2 (en) | 2009-03-24 | 2015-02-10 | Proteus S.A. | Methods for purifying phycotoxins, pharmaceutical compositions containing purified phycotoxins, and methods of use thereof |
| US20120034296A1 (en) * | 2009-04-08 | 2012-02-09 | Massachusetts Institute Of Technology | Prolonged duration local anesthesia with minimal toxicity |
| US9107925B2 (en) | 2010-02-10 | 2015-08-18 | Phytotox Limited | Sodium channel blocker for treatment of loss of superficial sensitivity |
| JP2014504184A (ja) | 2010-12-01 | 2014-02-20 | スパイナル・モデュレーション・インコーポレイテッド | 神経構造への薬剤の直接送達 |
| MX2015010749A (es) | 2013-03-14 | 2015-11-30 | Regeneron Pharma | Anticuerpos humanos para nav1.7. |
| CN105142625B (zh) | 2013-03-15 | 2019-09-06 | 儿童医学中心公司 | 用于长效局部麻醉的新蛤蚌毒素组合配制品 |
| US8992927B1 (en) | 2014-07-15 | 2015-03-31 | Kymab Limited | Targeting human NAV1.7 variants for treatment of pain |
| US8986694B1 (en) | 2014-07-15 | 2015-03-24 | Kymab Limited | Targeting human nav1.7 variants for treatment of pain |
| GB201403775D0 (en) | 2014-03-04 | 2014-04-16 | Kymab Ltd | Antibodies, uses & methods |
| WO2018083248A1 (en) | 2016-11-03 | 2018-05-11 | Kymab Limited | Antibodies, combinations comprising antibodies, biomarkers, uses & methods |
| CN107198689A (zh) * | 2017-07-11 | 2017-09-26 | 东新皓特（北京）生化科技有限公司 | 用于治疗疼痛病症的河豚毒素药物组合物及外用药 |
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| US4029793A (en) | 1973-06-12 | 1977-06-14 | Astra Pharmaceutical Products, Inc. | Synergistic local anesthetic compositions |
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| AU1888195A (en) * | 1994-03-17 | 1995-10-03 | Nanning Maple Leaf Pharmaceutical Co. Ltd. | The use of amino hydrogenated quinazoline compounds and derivatives thereof for abstaining from drug dependence |
| CN1072486C (zh) * | 1996-09-24 | 2001-10-10 | 王维国 | 用于戒毒、镇痛的药剂及其制法 |
| AU6883798A (en) * | 1997-04-02 | 1998-10-22 | Regents Of The University Of California, The | Method of anesthesia |
| US6326020B1 (en) * | 1997-05-16 | 2001-12-04 | Children's Medical Center Corporation | Local anesthetic formulations |
| CN1236773C (zh) * | 2000-11-22 | 2006-01-18 | 南宁枫叶药业有限公司 | 用于镇痛、麻醉或治疗药物依赖性的制剂 |
| CN1269482C (zh) * | 2001-05-18 | 2006-08-16 | 威克斯医药有限公司 | 钠离子通道阻断剂和阿片类镇痛剂在制备用于对哺乳动物进行协同镇痛的药物中的应用 |
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2000
- 2000-09-18 CN CNB001245171A patent/CN1284536C/zh not_active Expired - Lifetime
- 2000-10-25 US US09/695,053 patent/US6407088B1/en not_active Expired - Lifetime
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2001
- 2001-09-11 KR KR1020037003723A patent/KR100891568B1/ko active IP Right Grant
- 2001-09-11 CA CA2421562A patent/CA2421562C/en not_active Expired - Lifetime
- 2001-09-11 HU HU0302677A patent/HUP0302677A3/hu unknown
- 2001-09-11 AT AT01982091T patent/ATE447959T1/de not_active IP Right Cessation
- 2001-09-11 MX MXPA03002389A patent/MXPA03002389A/es active IP Right Grant
- 2001-09-11 YU YU17103A patent/YU17103A/sh unknown
- 2001-09-11 EE EEP200300106A patent/EE200300106A/xx unknown
- 2001-09-11 EP EP10180006.8A patent/EP2298306B1/en not_active Expired - Lifetime
- 2001-09-11 KR KR1020077023825A patent/KR20070112864A/ko not_active Application Discontinuation
- 2001-09-11 AU AU2002213785A patent/AU2002213785A1/en not_active Abandoned
- 2001-09-11 BR BR0113961-4A patent/BR0113961A/pt not_active IP Right Cessation
- 2001-09-11 EP EP04022073A patent/EP1563839B1/en not_active Expired - Lifetime
- 2001-09-11 SK SK373-2003A patent/SK3732003A3/sk unknown
- 2001-09-11 IL IL15434201A patent/IL154342A0/xx unknown
- 2001-09-11 AT AT04022073T patent/ATE542534T1/de active
- 2001-09-11 WO PCT/CN2001/001391 patent/WO2002022129A1/en active Application Filing
- 2001-09-11 ES ES10180006T patent/ES2435463T3/es not_active Expired - Lifetime
- 2001-09-11 PL PL36061601A patent/PL360616A1/xx unknown
- 2001-09-11 EP EP01982091A patent/EP1320369B1/en not_active Expired - Lifetime
- 2001-09-11 DE DE60140466T patent/DE60140466D1/de not_active Expired - Lifetime
- 2001-09-11 JP JP2002526380A patent/JP2004508404A/ja not_active Abandoned
- 2001-09-11 EA EA200300172A patent/EA004870B1/ru unknown
- 2001-11-09 UA UA2003032528A patent/UA76960C2/uk unknown
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2003
- 2003-02-14 IS IS6719A patent/IS6719A/is unknown
- 2003-02-27 NO NO20030915A patent/NO323960B1/no unknown
- 2003-03-06 ZA ZA200301852A patent/ZA200301852B/en unknown
- 2003-03-17 HR HR20030202A patent/HRP20030202A2/hr not_active Application Discontinuation
- 2003-03-31 BG BG107690A patent/BG107690A/bg unknown
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2778455C2 (ru) * | 2017-03-29 | 2022-08-19 | Сайтван Терапевтикс, Инк. | 11,13-модифицированные сакситоксины для лечения боли |
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