UA74145C2 - Модуляторы глюкокортикоидного рецептора - Google Patents

Модуляторы глюкокортикоидного рецептора Download PDF

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UA74145C2
UA74145C2 UA2001107363A UA2001107363A UA74145C2 UA 74145 C2 UA74145 C2 UA 74145C2 UA 2001107363 A UA2001107363 A UA 2001107363A UA 2001107363 A UA2001107363 A UA 2001107363A UA 74145 C2 UA74145 C2 UA 74145C2
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compound
alkyl
formula
pharmaceutically acceptable
isomer
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Ukrainian (uk)
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Роберт Лі Дау
Кевін Кун-Чін Ліу
Бредлі Пол Морган
Ендрю Гордон Свік
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Пфайзер Продактс Інк.
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    • C07D455/06—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing quinolizine ring systems directly condensed with at least one six-membered carbocyclic ring, e.g. protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing a quinolizine ring system condensed with only one six-membered carbocyclic ring, e.g. julolidine containing benzo [a] quinolizine ring systems
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Abstract

Изобретение касается нестероидных соединений формулы (І), которые являются селективными модуляторами (т.е., агонисты и антагонисты) стероидного рецептора, особенно глюкокортикоидного рецептора. Изобретение также касается фармацевтических композиций, которые содержат эти соединения, и способов использования этих соединений при лечении животных, которые нуждаются в терапии с использованием агониста и/или антагониста глюкокортикоидного рецептора. Модуляторы глюкокортикоидного рецептора полезны при лечении заболеваний, таких как ожирение, диабет, воспаление и другие. Изобретение также касается промежуточных соединений и способов получения этих соединений.
UA2001107363A 1999-04-30 2000-03-27 Модуляторы глюкокортикоидного рецептора UA74145C2 (ru)

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