UA73572C2 - 1,2-annelated quinoline enantiomer inhibiting farnesyl transferase - Google Patents
1,2-annelated quinoline enantiomer inhibiting farnesyl transferase Download PDFInfo
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- UA73572C2 UA73572C2 UA20021210152A UA20021210152A UA73572C2 UA 73572 C2 UA73572 C2 UA 73572C2 UA 20021210152 A UA20021210152 A UA 20021210152A UA 20021210152 A UA20021210152 A UA 20021210152A UA 73572 C2 UA73572 C2 UA 73572C2
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- compound
- mixture
- chlorophenyl
- cancer
- farnesyl transferase
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Classifications
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- C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
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- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
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Landscapes
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| EP00202181 | 2000-06-22 | ||
| PCT/EP2001/006747 WO2001098302A1 (en) | 2000-06-22 | 2001-06-13 | Farnesyl transferase inhibiting 1,2-annelated quinoline enantiomer |
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| UA73572C2 true UA73572C2 (en) | 2005-08-15 |
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| UA20021210152A UA73572C2 (en) | 2000-06-22 | 2001-06-13 | 1,2-annelated quinoline enantiomer inhibiting farnesyl transferase |
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| AU2003229688B2 (en) | 2002-04-15 | 2009-07-30 | Janssen Pharmaceutica N.V. | Farnesyl transferase inhibiting tricyclic quinazoline derivatives substituted with carbon-linked imidazoles or triazoles |
| US20050003422A1 (en) | 2003-07-01 | 2005-01-06 | Mitch Reponi | Methods for assessing and treating cancer |
| US11311519B2 (en) | 2014-05-01 | 2022-04-26 | Eiger Biopharmaceuticals, Inc. | Treatment of hepatitis delta virus infection |
| US10076512B2 (en) | 2014-05-01 | 2018-09-18 | Eiger Biopharmaceuticals, Inc. | Treatment of hepatitis delta virus infection |
| US20180338993A1 (en) * | 2014-12-04 | 2018-11-29 | Eiger Biopharmaceuticals, Inc. | Treatment of hepatitis delta virus infection |
| KR102514971B1 (ko) | 2015-04-21 | 2023-03-27 | 아이거 바이오파마슈티컬스 인코포레이티드 | 로나파르닙 및 리토나버를 포함하는 약제 조성물 |
| EP3277842B9 (en) | 2015-08-17 | 2020-01-15 | Kura Oncology, Inc. | Methods of treating cancer patients with farnesyl transferase inhibitors |
| PT3534885T (pt) | 2016-11-03 | 2021-04-13 | Kura Oncology Inc | Inibidores de farnesiltransferase para usar em métodos de tratamento do cancro |
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| GB1519765A (en) * | 1974-09-05 | 1978-08-02 | Ici Ltd | Pesticidal dihydrotetrazolo(1,5a) quinazolines compositions and processes |
| US4141979A (en) * | 1976-12-23 | 1979-02-27 | Pfizer Inc. | Tetrazolo[a]quinazol-5-ones antiallergy and antiulcer agents |
| GB9513577D0 (en) * | 1995-07-04 | 1995-09-06 | Brotherwood Rodney J | Improvements in passenger carrying vehicles |
| TW349948B (en) * | 1995-10-31 | 1999-01-11 | Janssen Pharmaceutica Nv | Farnesyl transferase inhibiting 2-quinolone derivatives |
| BR9610745A (pt) * | 1995-12-08 | 1999-07-13 | Janssen Pharmaceutica Nv | Derivados de (imidazol-5-il) metil-2-quinolinona inibindo a transferase da proteina farnesil |
| AU715658B2 (en) | 1996-04-03 | 2000-02-10 | Merck & Co., Inc. | Inhibitors of farnesyl-protein transferase |
| TW591030B (en) * | 1997-03-10 | 2004-06-11 | Janssen Pharmaceutica Nv | Farnesyl transferase inhibiting 1,8-annelated quinolinone derivatives substituted with N- or C-linked imidazoles |
| WO1998049157A1 (en) * | 1997-04-25 | 1998-11-05 | Janssen Pharmaceutica N.V. | Farnesyltransferase inhibiting quinazolinones |
| PT988038E (pt) | 1997-06-02 | 2002-12-31 | Janssen Pharmaceutica Nv | Derivados (imidazol-5-il)metil-2-quinolinona como inibidores da proliferacao de celulas dos musculos lisos |
| JP4530537B2 (ja) * | 1998-07-06 | 2010-08-25 | ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ | インビボ放射線増感特性をもつファルネシルタンパク質トランスフェラーゼ阻害剤 |
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| WO2000012499A1 (en) * | 1998-08-27 | 2000-03-09 | Pfizer Products Inc. | Alkynyl-substituted quinolin-2-one derivatives useful as anticancer agents |
| CA2341739C (en) * | 1998-08-27 | 2005-07-12 | Pfizer Products Inc. | Quinolin-2-one derivatives useful as anticancer agents |
| KR100712226B1 (ko) * | 1998-12-23 | 2007-04-27 | 얀센 파마슈티카 엔.브이. | 1,2-어닐링된 퀴놀린 유도체 |
| US6462201B1 (en) * | 1998-12-29 | 2002-10-08 | Isp Investments Inc. | Process for the production of N-vinyl-2-pyrrolidone by vinylation |
| EE200100425A (et) * | 1999-02-11 | 2002-12-16 | Pfizer Products Inc. | Heteroarüül-asendatud kinoliin-2-ooni derivaadid kui vähivastased vahendid |
| HN2000000266A (es) | 2000-01-21 | 2001-05-21 | Pfizer Prod Inc | Compuesto anticanceroso y metodo de separacion de enantiomeros util para sintetizar dicho compuesto. |
| ES2293972T3 (es) | 2000-02-24 | 2008-04-01 | Janssen Pharmaceutica N.V. | Regimen de dosificacion que comprende un inhibidor de la farnesil proteina transferasa para el tratamiento del cancer. |
| WO2002024686A2 (en) | 2000-09-25 | 2002-03-28 | Janssen Pharmaceutica N.V. | Farnesyl transferase inhibiting 6-heterocyclylmethyl quinoline and quinazoline derivatives |
| AU2001293835A1 (en) | 2000-09-25 | 2002-04-02 | Janssen Pharmaceutica N.V. | Farnesyl transferase inhibiting 6-heterocyclylmethyl quinolinone derivatives |
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2001
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2002
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