UA124942C2 - Спосіб одержання енантіомерів пірліндолу та їхніх солей - Google Patents

Спосіб одержання енантіомерів пірліндолу та їхніх солей

Info

Publication number
UA124942C2
UA124942C2 UAA201910929A UAA201910929A UA124942C2 UA 124942 C2 UA124942 C2 UA 124942C2 UA A201910929 A UAA201910929 A UA A201910929A UA A201910929 A UAA201910929 A UA A201910929A UA 124942 C2 UA124942 C2 UA 124942C2
Authority
UA
Ukraine
Prior art keywords
preparation
salts
pirlindole enantiomers
pirlindole
enantiomers
Prior art date
Application number
UAA201910929A
Other languages
English (en)
Inventor
Коста Перейра Роза Карла Патрісія да
Коста Перейра Роза Карла Патрисия да
Даміл Жуан Карлос Рамос
Дамил Жуан Карлос Рамос
Сімойнш Ана Ванесса Кордейру
Симойнш Ана Ванесса Кордейру
Серра Жуан Педро Сілва
Серра Жуан Педро Смилва
Original Assignee
Текнімеде, Сосіедаде Текніко-Медісінал, Са
Текнимеде, Сосиедаде Текнико-Медисинал, Са
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Текнімеде, Сосіедаде Текніко-Медісінал, Са, Текнимеде, Сосиедаде Текнико-Медисинал, Са filed Critical Текнімеде, Сосіедаде Текніко-Медісінал, Са
Publication of UA124942C2 publication Critical patent/UA124942C2/uk

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/06—Peri-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Даний винахід стосується поліпшеного способу одержання енантіомерів пірліндолу або їхньої фармацевтично прийнятної солі: , IIIII. WO 2018/193415 PCT/IB2018/052756
UAA201910929A 2017-04-21 2018-04-20 Спосіб одержання енантіомерів пірліндолу та їхніх солей UA124942C2 (uk)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
PT11003817 2017-04-21
EP17167852.7A EP3392251A1 (en) 2017-04-21 2017-04-24 Process for the preparation of pirlindole enantiomers and its salts
PCT/IB2018/052756 WO2018193415A1 (en) 2017-04-21 2018-04-20 Process for the preparation of pirlindole enantiomers and its salts

Publications (1)

Publication Number Publication Date
UA124942C2 true UA124942C2 (uk) 2021-12-15

Family

ID=58632261

Family Applications (1)

Application Number Title Priority Date Filing Date
UAA201910929A UA124942C2 (uk) 2017-04-21 2018-04-20 Спосіб одержання енантіомерів пірліндолу та їхніх солей

Country Status (20)

Country Link
US (1) US11008328B2 (uk)
EP (2) EP3392251A1 (uk)
JP (1) JP7121749B2 (uk)
KR (1) KR102526439B1 (uk)
CN (1) CN110914270B (uk)
AU (1) AU2018254239B2 (uk)
BR (1) BR112019022065A2 (uk)
CA (1) CA3060593A1 (uk)
CL (1) CL2019002966A1 (uk)
CO (1) CO2019012594A2 (uk)
CY (1) CY1124736T1 (uk)
EA (1) EA037179B1 (uk)
EC (1) ECSP19076874A (uk)
IL (1) IL270049B (uk)
PE (1) PE20191740A1 (uk)
PT (1) PT3612535T (uk)
SA (1) SA519410308B1 (uk)
UA (1) UA124942C2 (uk)
WO (1) WO2018193415A1 (uk)
ZA (1) ZA201907515B (uk)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011094840A1 (en) * 2010-02-03 2011-08-11 Biofume Technologies Inc. Preservative package comprising plant material

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3288860A (en) 1965-03-30 1966-11-29 Procter & Gamble Alkali metal salts of sulfinyl carbanions and alkali metal alkanesulfenates, processes for their preparation and reactions thereof with alkyl halides
IT1312539B1 (it) * 1999-04-16 2002-04-22 Erregierre Spa Processo per la preparazione del pirlindolo cloridrato.
RU2436786C1 (ru) * 2010-07-23 2011-12-20 Александр Васильевич Иващенко Замещенные индолы, противовирусный активный компонент, способ получения и применения
US10226460B2 (en) * 2014-05-09 2019-03-12 Tecnimede Sociedade Tecnico-Medicinal S.A. Pharmaceutically acceptable salts of pirlindole enantiomers for use in medicine
PL3057589T3 (pl) 2014-05-09 2018-01-31 Tecnimede Sociedade Tecnico Medicinal S (S)-Pirlindol lub jego farmaceutycznie dopuszczalne sole do zastosowania w medycynie
DK3140265T3 (da) 2014-05-09 2019-11-18 Tecnimede Sociedade Tecnico Medicinal S Fremgangsmåde til at opnå optisk aktive pirlindolenantiomerer og salte deraf
CN104774208A (zh) 2015-04-24 2015-07-15 南京靖龙药物研发有限公司 一种氘标记吡吲哚盐酸盐的制备方法

Also Published As

Publication number Publication date
SA519410308B1 (ar) 2021-11-25
AU2018254239A1 (en) 2019-10-31
EP3612535B1 (en) 2021-09-01
JP7121749B2 (ja) 2022-08-18
US20200190098A1 (en) 2020-06-18
ZA201907515B (en) 2020-11-25
IL270049B (en) 2022-02-01
CN110914270B (zh) 2022-05-03
CO2019012594A2 (es) 2020-01-17
PE20191740A1 (es) 2019-12-12
CL2019002966A1 (es) 2020-04-13
EA201992380A1 (ru) 2020-02-21
EP3392251A1 (en) 2018-10-24
CA3060593A1 (en) 2018-10-25
KR20190140970A (ko) 2019-12-20
ECSP19076874A (es) 2020-02-28
EA037179B1 (ru) 2021-02-16
US11008328B2 (en) 2021-05-18
CN110914270A (zh) 2020-03-24
WO2018193415A1 (en) 2018-10-25
BR112019022065A2 (pt) 2020-05-05
KR102526439B1 (ko) 2023-04-26
JP2020517662A (ja) 2020-06-18
WO2018193415A9 (en) 2019-08-08
EP3612535A1 (en) 2020-02-26
CY1124736T1 (el) 2022-07-22
AU2018254239B2 (en) 2022-05-26
PT3612535T (pt) 2021-12-07

Similar Documents

Publication Publication Date Title
WO2016130920A3 (en) Lrrk2 inhibitors and methods of making and using the same
TW201613859A (en) Analogs of PRIDOPIDINE, their preparation and use
WO2016079751A3 (en) A process for preparation of vortioxetine and polymorphs thereof
SA519402288B1 (ar) مركب بيريميدين واستخداماته الصيدلانية
WO2016125191A3 (en) Processes for the preparation of vortioxetine hydrobromide
NZ730816A (en) Quinoline carboxamides for use in the treatment of multiple myeloma
MX2020012771A (es) Metodos para preparar 5,6-dihidro-6-fenilbenzo[f]isoquinolin-2-ami na sustituida.
SG10201908248PA (en) Processes for preparing fluoroketolides
NZ732704A (en) Quinoline carboxamides for use in the treatment of leukemia
MX369506B (es) Composiciones de sales metálicas.
PH12016502235A1 (en) Pharmaceutically acceptable salts of pirlindole enantiomers for use in medicine
PH12017501955A1 (en) Tetrahydrofurane-fused aminohydrothiazine derivatives which are useful in the treatment of alzheimer`s disease
PH12017501869A1 (en) (s)-2'-vinyl-abscisic acid derivatives
EP3353149A4 (en) PROCESS FOR THE PREPARATION OF INDOLIN COMPOUNDS AND A NOVEL INDOLIN SALT
UA124942C2 (uk) Спосіб одержання енантіомерів пірліндолу та їхніх солей
GEP20207127B (en) 2-homopiperazine-1-yl-4h-1,3-benzothiazine-4-one derivatives and process for the preparation of 2-(homo)piperazine 1,3-benzothiazine-4-one hydrochlorides
MX2017000318A (es) Derivados del acido abscisico sustituido en 3'.
EP3856732C0 (en) PROCESS AND SALTS FOR THE PREPARATION OF 2,5-FURANEDICARBOXYLIC ACID
MX2019005504A (es) Potenciadores de bmp.
WO2018229796A3 (en) PROCESS FOR THE PREPARATION OF BETRIXABAN CHLORHYDRATE AND BETRIXABAN MALEATE SALT
WO2019014286A3 (en) IMPROVED PROCESSES FOR THE PREPARATION OF GUADECITABINE AND INTERMEDIATES THEREOF
EP3638220A4 (en) PREPARATION OF (S, S
MX2017008655A (es) Derivados de jasmonato y composiciones de los mismos.
SI3612535T1 (sl) Postopek za pripravo pirlindolnih enantiomerov in njihovih soli
PL3612535T3 (pl) Sposób otrzymywania enancjomerów pirlindolu i jego soli