DK3140265T3 - Fremgangsmåde til at opnå optisk aktive pirlindolenantiomerer og salte deraf - Google Patents

Fremgangsmåde til at opnå optisk aktive pirlindolenantiomerer og salte deraf Download PDF

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Publication number
DK3140265T3
DK3140265T3 DK14726442T DK14726442T DK3140265T3 DK 3140265 T3 DK3140265 T3 DK 3140265T3 DK 14726442 T DK14726442 T DK 14726442T DK 14726442 T DK14726442 T DK 14726442T DK 3140265 T3 DK3140265 T3 DK 3140265T3
Authority
DK
Denmark
Prior art keywords
indolenients
pirl
getting
salts
procedure
Prior art date
Application number
DK14726442T
Other languages
English (en)
Inventor
Oliveira Santos Pedro Paulo De Lacerda E
Filipe Augusto Eugénio Pardal
Pedroso Pedro Filipe EufrãSio
Pecorelli Susana Marques Almeida
Caixado Carlos Alberto Eufrásio Casimiro
João Carlos Ramos Damil
Ana Sofia Da Conceição Lopes
Original Assignee
Tecnimede Sociedade Tecnico Medicinal S
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tecnimede Sociedade Tecnico Medicinal S filed Critical Tecnimede Sociedade Tecnico Medicinal S
Application granted granted Critical
Publication of DK3140265T3 publication Critical patent/DK3140265T3/da

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/06Peri-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B57/00Separation of optically-active compounds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07Optical isomers
DK14726442T 2014-05-09 2014-05-09 Fremgangsmåde til at opnå optisk aktive pirlindolenantiomerer og salte deraf DK3140265T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/PT2014/000027 WO2015171003A1 (en) 2014-05-09 2014-05-09 Process for obtaining optically active pirlindole enantiomers and salts thereof

Publications (1)

Publication Number Publication Date
DK3140265T3 true DK3140265T3 (da) 2019-11-18

Family

ID=50819929

Family Applications (1)

Application Number Title Priority Date Filing Date
DK14726442T DK3140265T3 (da) 2014-05-09 2014-05-09 Fremgangsmåde til at opnå optisk aktive pirlindolenantiomerer og salte deraf

Country Status (30)

Country Link
US (1) US9682986B2 (da)
EP (1) EP3140265B1 (da)
JP (1) JP6516769B2 (da)
KR (1) KR102258709B1 (da)
CN (1) CN106414376B (da)
AU (1) AU2014393488C1 (da)
BR (1) BR112016025918B1 (da)
CA (1) CA2948604C (da)
CY (1) CY1122367T1 (da)
DK (1) DK3140265T3 (da)
EC (1) ECSP16086217A (da)
ES (1) ES2753403T3 (da)
HR (1) HRP20192029T1 (da)
HU (1) HUE046437T2 (da)
IL (1) IL248853B (da)
LT (1) LT3140265T (da)
MA (1) MA39449A1 (da)
MX (1) MX357918B (da)
NZ (1) NZ726129A (da)
PH (1) PH12016502234A1 (da)
PL (1) PL3140265T3 (da)
PT (1) PT3140265T (da)
RS (1) RS59499B1 (da)
RU (1) RU2666731C2 (da)
SA (1) SA516380265B1 (da)
SI (1) SI3140265T1 (da)
TN (1) TN2016000496A1 (da)
UA (1) UA118696C2 (da)
WO (1) WO2015171003A1 (da)
ZA (1) ZA201607722B (da)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TN2016000495A1 (en) * 2014-05-09 2018-04-04 Tecnimede Sociedade Tecnico Medicinal S Pharmaceutically acceptable salts of pirlindole enantiomers for use in medicine.
CN106414376B (zh) 2014-05-09 2019-06-07 特克尼梅德医疗技术股份公司 获得光学活性吡吲哚对映异构体及其盐的方法
EP3392251A1 (en) 2017-04-21 2018-10-24 Tecnimede-Sociedade Tecnico-Medicinal, S.A. Process for the preparation of pirlindole enantiomers and its salts
EP3392250A1 (en) * 2017-04-21 2018-10-24 Tecnimede-Sociedade Tecnico-Medicinal, S.A. Process for the preparation of piperazine ring for the synthesis of pyrazinocarbazole derivatives

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2281085C2 (ru) * 2004-05-25 2006-08-10 Закрытое акционерное общество "Мастерлек" Антидепрессивные лекарственные средства для парентерального применения на основе сульфонатных солей пирлиндола
CN106414376B (zh) 2014-05-09 2019-06-07 特克尼梅德医疗技术股份公司 获得光学活性吡吲哚对映异构体及其盐的方法

Also Published As

Publication number Publication date
RS59499B1 (sr) 2019-12-31
MX2016014703A (es) 2017-05-23
CA2948604C (en) 2021-06-15
MX357918B (es) 2018-07-30
JP2017514883A (ja) 2017-06-08
BR112016025918A2 (da) 2017-08-15
CN106414376A (zh) 2017-02-15
US9682986B2 (en) 2017-06-20
SA516380265B1 (ar) 2019-11-04
IL248853B (en) 2020-01-30
ECSP16086217A (es) 2017-02-24
AU2014393488C1 (en) 2020-07-16
PL3140265T3 (pl) 2020-02-28
CA2948604A1 (en) 2015-11-12
AU2014393488A1 (en) 2016-11-24
AU2014393488B2 (en) 2018-11-08
CN106414376B (zh) 2019-06-07
PH12016502234B1 (en) 2017-01-09
NZ726129A (en) 2019-03-29
UA118696C2 (uk) 2019-02-25
HUE046437T2 (hu) 2020-03-30
EP3140265A1 (en) 2017-03-15
TN2016000496A1 (en) 2018-04-04
JP6516769B2 (ja) 2019-05-22
EP3140265B1 (en) 2019-08-28
US20170145024A1 (en) 2017-05-25
SI3140265T1 (sl) 2019-12-31
BR112016025918B1 (pt) 2023-05-16
LT3140265T (lt) 2019-12-10
ZA201607722B (en) 2022-05-25
RU2016148181A (ru) 2018-06-13
IL248853A0 (en) 2017-01-31
MA39449A1 (fr) 2017-11-30
KR102258709B1 (ko) 2021-06-01
ES2753403T3 (es) 2020-04-08
WO2015171003A1 (en) 2015-11-12
RU2016148181A3 (da) 2018-06-13
RU2666731C2 (ru) 2018-09-12
CY1122367T1 (el) 2021-01-27
PH12016502234A1 (en) 2017-01-09
HRP20192029T1 (hr) 2020-02-07
PT3140265T (pt) 2019-12-02
KR20170004995A (ko) 2017-01-11

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DK3140265T3 (da) Fremgangsmåde til at opnå optisk aktive pirlindolenantiomerer og salte deraf