MA39449A1 - Procédé d'obtention d'énantiomères de pirlindole optiquement actifs et de sels de ceux-ci - Google Patents
Procédé d'obtention d'énantiomères de pirlindole optiquement actifs et de sels de ceux-ciInfo
- Publication number
- MA39449A1 MA39449A1 MA39449A MA39449A MA39449A1 MA 39449 A1 MA39449 A1 MA 39449A1 MA 39449 A MA39449 A MA 39449A MA 39449 A MA39449 A MA 39449A MA 39449 A1 MA39449 A1 MA 39449A1
- Authority
- MA
- Morocco
- Prior art keywords
- optically active
- salts
- obtaining enantiomers
- pirlindole
- active pirlindole
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/06—Peri-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B57/00—Separation of optically-active compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/07—Optical isomers
Abstract
La présente invention concerne un nouveau procédé d'obtention d'énantiomères de pirlindole optiquement actifs, sous forme d'une base libre ou sous forme de sels pharmaceutiquement acceptables. Les produits obtenus selon la présente invention sont énantiomériquement purs et sont utiles en médecine.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/PT2014/000027 WO2015171003A1 (fr) | 2014-05-09 | 2014-05-09 | Procédé d'obtention d'énantiomères de pirlindole optiquement actifs et de sels de ceux-ci |
Publications (1)
Publication Number | Publication Date |
---|---|
MA39449A1 true MA39449A1 (fr) | 2017-11-30 |
Family
ID=50819929
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MA39449A MA39449A1 (fr) | 2014-05-09 | 2014-05-09 | Procédé d'obtention d'énantiomères de pirlindole optiquement actifs et de sels de ceux-ci |
Country Status (30)
Country | Link |
---|---|
US (1) | US9682986B2 (fr) |
EP (1) | EP3140265B1 (fr) |
JP (1) | JP6516769B2 (fr) |
KR (1) | KR102258709B1 (fr) |
CN (1) | CN106414376B (fr) |
AU (1) | AU2014393488C1 (fr) |
BR (1) | BR112016025918B1 (fr) |
CA (1) | CA2948604C (fr) |
CY (1) | CY1122367T1 (fr) |
DK (1) | DK3140265T3 (fr) |
EC (1) | ECSP16086217A (fr) |
ES (1) | ES2753403T3 (fr) |
HR (1) | HRP20192029T1 (fr) |
HU (1) | HUE046437T2 (fr) |
IL (1) | IL248853B (fr) |
LT (1) | LT3140265T (fr) |
MA (1) | MA39449A1 (fr) |
MX (1) | MX357918B (fr) |
NZ (1) | NZ726129A (fr) |
PH (1) | PH12016502234B1 (fr) |
PL (1) | PL3140265T3 (fr) |
PT (1) | PT3140265T (fr) |
RS (1) | RS59499B1 (fr) |
RU (1) | RU2666731C2 (fr) |
SA (1) | SA516380265B1 (fr) |
SI (1) | SI3140265T1 (fr) |
TN (1) | TN2016000496A1 (fr) |
UA (1) | UA118696C2 (fr) |
WO (1) | WO2015171003A1 (fr) |
ZA (1) | ZA201607722B (fr) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2015171003A1 (fr) | 2014-05-09 | 2015-11-12 | Tecnimede Sociedade Tecnico-Medicinal S.A. | Procédé d'obtention d'énantiomères de pirlindole optiquement actifs et de sels de ceux-ci |
WO2015171002A1 (fr) * | 2014-05-09 | 2015-11-12 | Tecnimede Sociedade Tecnico-Medicinal S.A. | Sels pharmaceutiquement acceptables d'énantiomères de pirlindole s'utilisant en médecine |
EP3392250A1 (fr) * | 2017-04-21 | 2018-10-24 | Tecnimede-Sociedade Tecnico-Medicinal, S.A. | Procedé pour la préparation de l'anneau de pipérazine pour la synthèse de pyrazinocarbazole |
EP3392251A1 (fr) | 2017-04-21 | 2018-10-24 | Tecnimede-Sociedade Tecnico-Medicinal, S.A. | Procedé pour la préparation des enantiomères de pirlindole et leurs sels |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
RU2281085C2 (ru) * | 2004-05-25 | 2006-08-10 | Закрытое акционерное общество "Мастерлек" | Антидепрессивные лекарственные средства для парентерального применения на основе сульфонатных солей пирлиндола |
WO2015171003A1 (fr) | 2014-05-09 | 2015-11-12 | Tecnimede Sociedade Tecnico-Medicinal S.A. | Procédé d'obtention d'énantiomères de pirlindole optiquement actifs et de sels de ceux-ci |
-
2014
- 2014-05-09 WO PCT/PT2014/000027 patent/WO2015171003A1/fr active Application Filing
- 2014-05-09 AU AU2014393488A patent/AU2014393488C1/en active Active
- 2014-05-09 PT PT147264428T patent/PT3140265T/pt unknown
- 2014-05-09 TN TN2016000496A patent/TN2016000496A1/en unknown
- 2014-05-09 US US15/309,906 patent/US9682986B2/en active Active
- 2014-05-09 EP EP14726442.8A patent/EP3140265B1/fr active Active
- 2014-05-09 MA MA39449A patent/MA39449A1/fr unknown
- 2014-05-09 HU HUE14726442A patent/HUE046437T2/hu unknown
- 2014-05-09 NZ NZ726129A patent/NZ726129A/en unknown
- 2014-05-09 UA UAA201611334A patent/UA118696C2/uk unknown
- 2014-05-09 DK DK14726442T patent/DK3140265T3/da active
- 2014-05-09 PL PL14726442T patent/PL3140265T3/pl unknown
- 2014-05-09 JP JP2016567540A patent/JP6516769B2/ja active Active
- 2014-05-09 CN CN201480078731.6A patent/CN106414376B/zh active Active
- 2014-05-09 MX MX2016014703A patent/MX357918B/es active IP Right Grant
- 2014-05-09 RS RS20191433A patent/RS59499B1/sr unknown
- 2014-05-09 LT LT14726442T patent/LT3140265T/lt unknown
- 2014-05-09 KR KR1020167031371A patent/KR102258709B1/ko active IP Right Grant
- 2014-05-09 SI SI201431386T patent/SI3140265T1/sl unknown
- 2014-05-09 BR BR112016025918-1A patent/BR112016025918B1/pt active IP Right Grant
- 2014-05-09 RU RU2016148181A patent/RU2666731C2/ru active
- 2014-05-09 ES ES14726442T patent/ES2753403T3/es active Active
- 2014-05-09 CA CA2948604A patent/CA2948604C/fr active Active
-
2016
- 2016-11-09 IL IL248853A patent/IL248853B/en active IP Right Grant
- 2016-11-09 PH PH12016502234A patent/PH12016502234B1/en unknown
- 2016-11-09 SA SA516380265A patent/SA516380265B1/ar unknown
- 2016-11-09 ZA ZA2016/07722A patent/ZA201607722B/en unknown
- 2016-11-09 EC ECIEPI201686217A patent/ECSP16086217A/es unknown
-
2019
- 2019-11-08 HR HRP20192029TT patent/HRP20192029T1/hr unknown
- 2019-11-13 CY CY20191101194T patent/CY1122367T1/el unknown
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