CO2019012594A2 - Proceso para la preparación de enantiómeros de pirlindol y sus sales - Google Patents

Proceso para la preparación de enantiómeros de pirlindol y sus sales

Info

Publication number
CO2019012594A2
CO2019012594A2 CONC2019/0012594A CO2019012594A CO2019012594A2 CO 2019012594 A2 CO2019012594 A2 CO 2019012594A2 CO 2019012594 A CO2019012594 A CO 2019012594A CO 2019012594 A2 CO2019012594 A2 CO 2019012594A2
Authority
CO
Colombia
Prior art keywords
pirlindole
enantiomers
preparation
salts
pharmaceutically acceptable
Prior art date
Application number
CONC2019/0012594A
Other languages
English (en)
Inventor
Costa Pereira Rosa Carla Patrícia Da
Damil João Carlos Ramos
Simões Ana Vanessa Cordeiro
Serra João Pedro Silva
Original Assignee
Tecnimede Soc Tecnico Medicinal Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tecnimede Soc Tecnico Medicinal Sa filed Critical Tecnimede Soc Tecnico Medicinal Sa
Publication of CO2019012594A2 publication Critical patent/CO2019012594A2/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/06—Peri-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

La presente invención se refiere a un proceso mejorado para la preparación de enantiómeros de Pirlindol, o una sal farmacéuticamente aceptable de los mismos.
CONC2019/0012594A 2017-04-21 2019-11-12 Proceso para la preparación de enantiómeros de pirlindol y sus sales CO2019012594A2 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
PT11003817 2017-04-21
EP17167852.7A EP3392251A1 (en) 2017-04-21 2017-04-24 Process for the preparation of pirlindole enantiomers and its salts
PCT/IB2018/052756 WO2018193415A1 (en) 2017-04-21 2018-04-20 Process for the preparation of pirlindole enantiomers and its salts

Publications (1)

Publication Number Publication Date
CO2019012594A2 true CO2019012594A2 (es) 2020-01-17

Family

ID=58632261

Family Applications (1)

Application Number Title Priority Date Filing Date
CONC2019/0012594A CO2019012594A2 (es) 2017-04-21 2019-11-12 Proceso para la preparación de enantiómeros de pirlindol y sus sales

Country Status (20)

Country Link
US (1) US11008328B2 (es)
EP (2) EP3392251A1 (es)
JP (1) JP7121749B2 (es)
KR (1) KR102526439B1 (es)
CN (1) CN110914270B (es)
AU (1) AU2018254239B2 (es)
BR (1) BR112019022065A2 (es)
CA (1) CA3060593A1 (es)
CL (1) CL2019002966A1 (es)
CO (1) CO2019012594A2 (es)
CY (1) CY1124736T1 (es)
EA (1) EA037179B1 (es)
EC (1) ECSP19076874A (es)
IL (1) IL270049B (es)
PE (1) PE20191740A1 (es)
PT (1) PT3612535T (es)
SA (1) SA519410308B1 (es)
UA (1) UA124942C2 (es)
WO (1) WO2018193415A1 (es)
ZA (1) ZA201907515B (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011094840A1 (en) * 2010-02-03 2011-08-11 Biofume Technologies Inc. Preservative package comprising plant material

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3288859A (en) 1965-03-30 1966-11-29 Procter & Gamble Reactions of alkali metal salts of sulfinyl carbanions and alkanesulfenates with epoxy compounds and novel compounds derived therefrom
IT1312539B1 (it) * 1999-04-16 2002-04-22 Erregierre Spa Processo per la preparazione del pirlindolo cloridrato.
RU2436786C1 (ru) * 2010-07-23 2011-12-20 Александр Васильевич Иващенко Замещенные индолы, противовирусный активный компонент, способ получения и применения
CN106456637B (zh) 2014-05-09 2020-06-09 特克尼梅德医疗技术股份公司 (s)-吡吲哚及其药学上可接受的盐的药学用途
AU2014393487B2 (en) * 2014-05-09 2020-01-02 Tecnimede Sociedade Tecnico-Medicinal S.A. Pharmaceutically acceptable salts of pirlindole enantiomers for use in medicine
CA2948604C (en) 2014-05-09 2021-06-15 Tecnimede Sociedade Tecnico-Medicinal S.A. Process for obtaining optically active pirlindole enantiomers and salts thereof
CN104774208A (zh) * 2015-04-24 2015-07-15 南京靖龙药物研发有限公司 一种氘标记吡吲哚盐酸盐的制备方法

Also Published As

Publication number Publication date
CA3060593A1 (en) 2018-10-25
KR102526439B1 (ko) 2023-04-26
CN110914270A (zh) 2020-03-24
IL270049B (en) 2022-02-01
AU2018254239B2 (en) 2022-05-26
EP3612535B1 (en) 2021-09-01
WO2018193415A1 (en) 2018-10-25
WO2018193415A9 (en) 2019-08-08
AU2018254239A1 (en) 2019-10-31
ECSP19076874A (es) 2020-02-28
EP3392251A1 (en) 2018-10-24
SA519410308B1 (ar) 2021-11-25
KR20190140970A (ko) 2019-12-20
EP3612535A1 (en) 2020-02-26
PT3612535T (pt) 2021-12-07
JP2020517662A (ja) 2020-06-18
UA124942C2 (uk) 2021-12-15
ZA201907515B (en) 2020-11-25
CN110914270B (zh) 2022-05-03
PE20191740A1 (es) 2019-12-12
US20200190098A1 (en) 2020-06-18
CL2019002966A1 (es) 2020-04-13
EA037179B1 (ru) 2021-02-16
JP7121749B2 (ja) 2022-08-18
CY1124736T1 (el) 2022-07-22
US11008328B2 (en) 2021-05-18
BR112019022065A2 (pt) 2020-05-05
EA201992380A1 (ru) 2020-02-21

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