UA122127C2 - Лентивірусний вектор - Google Patents
Лентивірусний вектор Download PDFInfo
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- UA122127C2 UA122127C2 UAA201612986A UAA201612986A UA122127C2 UA 122127 C2 UA122127 C2 UA 122127C2 UA A201612986 A UAA201612986 A UA A201612986A UA A201612986 A UAA201612986 A UA A201612986A UA 122127 C2 UA122127 C2 UA 122127C2
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Classifications
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- A61K48/005—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'active' part of the composition delivered, i.e. the nucleic acid delivered
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- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4712—Cystic fibrosis
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- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/745—Blood coagulation or fibrinolysis factors
- C07K14/755—Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
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- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/33—Fusion polypeptide fusions for targeting to specific cell types, e.g. tissue specific targeting, targeting of a bacterial subspecies
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- C12N2740/15032—Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent
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- C12N2810/6072—Vectors comprising as targeting moiety peptide derived from defined protein from viruses negative strand RNA viruses
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| JP2018174874A (ja) * | 2017-04-19 | 2018-11-15 | 国立大学法人 東京医科歯科大学 | 上皮細胞の水分泌機能測定方法 |
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| GB201814590D0 (en) * | 2018-09-07 | 2018-10-24 | Oxford Biomedica Ltd | Viral vector production system |
| EP3775236A1 (en) | 2018-04-12 | 2021-02-17 | Krystal Biotech, LLC | Compositions and methods for the treatment of autosomal recessive congenital ichthyosis |
| MX2020011257A (es) | 2018-04-27 | 2021-01-15 | Krystal Biotech Inc | Ácidos nucleicos recombinantes que codifican una o más proteínas cosméticas para usos estéticos. |
| WO2020009444A1 (ko) * | 2018-07-02 | 2020-01-09 | 서울대학교산학협력단 | 세포융합 기술을 이용한 유전자 및 세포 치료제 및 이의 용도 |
| CN112384247B (zh) * | 2018-07-02 | 2024-09-27 | 库拉米斯公司 | 利用细胞融合技术的基因及细胞治疗剂以及其的用途 |
| AU2019346549B2 (en) | 2018-09-24 | 2024-09-12 | Krystal Biotech, Inc. | Compositions and methods for the treatment of Netherton Syndrome |
| EP3856914A1 (en) | 2018-09-26 | 2021-08-04 | Krystal Biotech, Inc. | Compositions and methods for the treatment of skin diseases |
| CN113454105A (zh) | 2019-02-08 | 2021-09-28 | 克里斯托生物技术股份有限公司 | 用于递送cftr多肽的组合物和方法 |
| KR20210151785A (ko) * | 2019-03-13 | 2021-12-14 | 제너레이션 바이오 컴퍼니 | 비바이러스성 dna 벡터 및 fviii 치료제 발현을 위한 이의 용도 |
| CN112575034B (zh) * | 2019-09-29 | 2023-04-25 | 济南赛尔生物科技股份有限公司 | 一种治疗a型血友病的产品及应用 |
| EP4077688A1 (en) * | 2019-12-20 | 2022-10-26 | Krystal Biotech, Inc. | Compositions and methods for gene delivery to the airways and/or lungs |
| EP4143326A1 (en) * | 2020-04-27 | 2023-03-08 | University of Iowa Research Foundation | Compositions and methods for the treatment of cystic fibrosis |
| US20230190871A1 (en) | 2020-05-20 | 2023-06-22 | Sana Biotechnology, Inc. | Methods and compositions for treatment of viral infections |
| EP4162036A1 (en) | 2020-06-09 | 2023-04-12 | Inozyme Pharma, Inc. | Soluble enpp1 or enpp3 proteins and uses thereof |
| JP2023537565A (ja) * | 2020-06-24 | 2023-09-04 | バイオベラティブ セラピューティクス インコーポレイテッド | タンパク質を発現するように改変されたレンチウイルスベクターの調製物から遊離第ｖｉｉｉ因子を除去する方法 |
| WO2022047316A1 (en) | 2020-08-28 | 2022-03-03 | Sana Biotechnology, Inc. | Modified anti-viral binding agents |
| CA3191743A1 (en) * | 2020-09-16 | 2022-03-24 | Generation Bio Co. | Non-viral dna vectors and uses thereof for expressing fviii therapeutics |
| GB202100688D0 (en) * | 2021-01-19 | 2021-03-03 | Autolus Ltd | Process |
| GB202102832D0 (en) * | 2021-02-26 | 2021-04-14 | Ip2Ipo Innovations Ltd | Retroviral vectors |
| IL307350A (en) | 2021-04-02 | 2023-11-01 | Krystal Biotech Inc | Viral vectors for cancer treatment |
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| WO2023114949A1 (en) | 2021-12-16 | 2023-06-22 | Sana Biotechnology, Inc. | Methods and systems of particle production |
| US20250082777A1 (en) | 2022-01-10 | 2025-03-13 | Sana Biotechnology, Inc. | Methods of ex vivo dosing and administration of lipid particles or viral vectors and related systems and uses |
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| WO2025184529A1 (en) | 2024-03-01 | 2025-09-04 | Sana Biotechnology, Inc. | Viral particles with fusogen display and related compositions and methods |
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| AU2221600A (en) * | 1998-12-31 | 2000-07-31 | Chiron Corporation | Improved expression of hiv polypeptides and production of virus-like particles |
| CA2413995C (en) * | 2000-06-01 | 2013-08-13 | Dnavec Research Inc. | Pseudotype retroviral vectors containing membrane proteins having hemagglutinin activity |
| US20050048030A1 (en) * | 2001-09-28 | 2005-03-03 | Raymond Pickles | Paramyxoviruses as gene transfer vectors to lung cells |
| CA2462628C (en) * | 2001-10-02 | 2019-08-20 | Institut Clayton De La Recherche | Restricted expression lentiviral vectors |
| EP1950307B8 (en) * | 2005-10-28 | 2016-02-24 | IP Pharma Co., Ltd. | Gene transfer into airway epithelial stem cell by using lentiviral vector pseudotyped with rna virus spike protein |
| GB0606190D0 (en) * | 2006-03-28 | 2006-05-10 | Isis Innovation | Construct |
| EP1950303A1 (de) | 2007-01-26 | 2008-07-30 | Bayer CropScience AG | Genetisch modifizierte Pflanzen, die eine Stärke mit geringem Amylosegehalt und erhöhtem Quellvermögen synthetisieren |
| DK2623605T3 (en) * | 2007-04-09 | 2019-03-25 | Univ Florida | RAAV VECTOR COMPOSITIONS WITH TYROSIN MODIFIED CAPSIDE PROTEINS AND PROCEDURES FOR USE THEREOF |
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- 2015-04-23 HU HUE15720762A patent/HUE051269T2/hu unknown
- 2015-04-23 PL PL15720762T patent/PL3145949T3/pl unknown
- 2015-04-23 SI SI201531275T patent/SI3145949T1/sl unknown
- 2015-04-23 US US15/312,026 patent/US10704061B2/en active Active
- 2015-04-23 WO PCT/GB2015/051201 patent/WO2015177501A1/en not_active Ceased
- 2015-04-23 AU AU2015263150A patent/AU2015263150B2/en active Active
- 2015-04-23 ES ES15720762T patent/ES2805045T3/es active Active
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- 2015-04-23 CA CA2947125A patent/CA2947125C/en active Active
- 2015-04-23 SM SM20200360T patent/SMT202000360T1/it unknown
- 2015-04-23 PT PT157207622T patent/PT3145949T/pt unknown
- 2015-04-23 UA UAA201612986A patent/UA122127C2/uk unknown
- 2015-04-23 DK DK15720762.2T patent/DK3145949T3/da active
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2020
- 2020-07-03 CY CY20201100617T patent/CY1123413T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| LT3145949T (lt) | 2020-08-25 |
| JP2017521049A (ja) | 2017-08-03 |
| CA2947125C (en) | 2023-02-28 |
| GB201409089D0 (en) | 2014-07-02 |
| US20170096684A1 (en) | 2017-04-06 |
| SMT202000360T1 (it) | 2020-09-10 |
| EP3145949A1 (en) | 2017-03-29 |
| PT3145949T (pt) | 2020-07-13 |
| CA2947125A1 (en) | 2015-11-26 |
| DK3145949T3 (da) | 2020-06-29 |
| EP3145949B1 (en) | 2020-04-08 |
| JP6637444B2 (ja) | 2020-01-29 |
| CY1123413T1 (el) | 2021-12-31 |
| ES2805045T3 (es) | 2021-02-10 |
| PL3145949T3 (pl) | 2021-01-25 |
| AU2015263150A1 (en) | 2016-11-10 |
| HUE051269T2 (hu) | 2021-03-01 |
| AU2015263150B2 (en) | 2020-04-16 |
| SI3145949T1 (sl) | 2020-08-31 |
| WO2015177501A1 (en) | 2015-11-26 |
| EA201692361A1 (ru) | 2017-05-31 |
| GB2526339A (en) | 2015-11-25 |
| HRP20200930T1 (hr) | 2020-09-18 |
| EA038966B1 (ru) | 2021-11-16 |
| US10704061B2 (en) | 2020-07-07 |
| ME03789B (me) | 2021-04-20 |
| RS60586B1 (sr) | 2020-08-31 |
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