TWI714015B - 新穎啓動子及使用該啓動子製造l-胺基酸的方法 - Google Patents

新穎啓動子及使用該啓動子製造l-胺基酸的方法 Download PDF

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Publication number
TWI714015B
TWI714015B TW108107855A TW108107855A TWI714015B TW I714015 B TWI714015 B TW I714015B TW 108107855 A TW108107855 A TW 108107855A TW 108107855 A TW108107855 A TW 108107855A TW I714015 B TWI714015 B TW I714015B
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Taiwan
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polynucleotide
microorganism
gene
item
patent application
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TW108107855A
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Chinese (zh)
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TW201940501A (zh
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崔先亨
張眞淑
金亨俊
尹炳勳
李智軟
崔允禎
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南韓商Ｃｊ第一製糖股份有限公司
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C12N15/77—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Corynebacterium; for Brevibacterium
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/005—Amino acids other than alpha- or beta amino acids, e.g. gamma amino acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y101/00—Oxidoreductases acting on the CH-OH group of donors (1.1)
    • C12Y101/01—Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)
    • C12Y101/01027—L-Lactate dehydrogenase (1.1.1.27)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/14—Glutamic acid; Glutamine

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • General Preparation And Processing Of Foods (AREA)
TW108107855A 2018-03-09 2019-03-08 新穎啓動子及使用該啓動子製造l-胺基酸的方法 TWI714015B (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR10-2018-0028184 2018-03-09
KR20180028184 2018-03-09

Publications (2)

Publication Number Publication Date
TW201940501A TW201940501A (zh) 2019-10-16
TWI714015B true TWI714015B (zh) 2020-12-21

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ID=67847318

Family Applications (1)

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TW108107855A TWI714015B (zh) 2018-03-09 2019-03-08 新穎啓動子及使用該啓動子製造l-胺基酸的方法

Country Status (13)

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US (1) US11352608B2 (de)
EP (1) EP3763819A4 (de)
JP (1) JP7018128B2 (de)
KR (1) KR102132342B1 (de)
CN (1) CN110709517B (de)
AR (1) AR114670A1 (de)
AU (1) AU2019232209B2 (de)
BR (1) BR112020004575B1 (de)
CA (1) CA3073607C (de)
SG (1) SG11202002185SA (de)
TW (1) TWI714015B (de)
WO (1) WO2019172702A1 (de)
ZA (1) ZA202001382B (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2022152036A1 (zh) * 2021-01-12 2022-07-21 中国科学院天津工业生物技术研究所 具有启动子活性的多核苷酸及其在生产目标化合物中的用途
KR102339264B1 (ko) * 2021-05-07 2021-12-14 씨제이제일제당 주식회사 신규 프로모터 및 이의 용도
KR102339271B1 (ko) * 2021-05-07 2021-12-14 씨제이제일제당 주식회사 신규 프로모터 및 이의 용도
CN113994003B (zh) * 2021-05-07 2022-10-14 Cj第一制糖株式会社 新型启动子及其用途
CA3171537A1 (en) * 2021-05-20 2022-11-20 Nara Kwon Novel promoter and use thereof
KR102685904B1 (ko) * 2021-05-20 2024-07-19 씨제이제일제당 주식회사 신규 프로모터 및 이의 용도
WO2022265130A1 (ko) * 2021-06-15 2022-12-22 씨제이제일제당 (주) 신규 프로모터 및 이의 용도

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7141388B2 (en) * 2000-11-15 2006-11-28 Archer-Daniels-Midland Company Nucleotide sequences for transcriptional regulation in corynebacterium glutamicum

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Publication number Priority date Publication date Assignee Title
US3220929A (en) 1964-02-10 1965-11-30 Kyowa Hakko Kogyo Kk Microbiological production of amino acid by reductive amination
AU746542B2 (en) 1998-03-18 2002-05-02 Ajinomoto Co., Inc. L-glutamic acid-producing bacterium and method for producing L-glutamic acid
KR100292299B1 (ko) 1999-03-22 2001-06-01 손경식 글루탐산 생산 미생물 및 이를 이용한 글루탐산 생산방법
KR100924065B1 (ko) 2006-09-15 2009-10-27 씨제이제일제당 (주) Ｌ－라이신 생산능이 향상된 코리네박테리아 및 그를 이용한 ｌ－라이신 생산 방법
JP2016165225A (ja) * 2013-07-09 2016-09-15 味の素株式会社 有用物質の製造方法
KR101518860B1 (ko) * 2013-10-11 2015-05-12 씨제이제일제당 (주) L-아미노산의 생산 방법
CN107012160A (zh) * 2017-05-15 2017-08-04 天津大学 高产琥珀酸的谷氨酸棒杆菌菌株及构建方法及应用

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7141388B2 (en) * 2000-11-15 2006-11-28 Archer-Daniels-Midland Company Nucleotide sequences for transcriptional regulation in corynebacterium glutamicum

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
NCBI GenBank: .1, Corynebacterium glutamicum ldhA gene, promoter region [online] https://www.ncbi.nlm.nih.gov/nuccore/.1/ 2009/07/22. Toyoda K. et al., Molecular mechanism of SugR-mediated sugar-dependent expression of the ldhA gene encoding L-lactate dehydrogenase in Corynebacterium glutamicum. Applied Microbiology and Biotechnology, vol. 83, no. 2, 2009 May, pages 315-327. *
NCBI GenBank: AB191244.1, Corynebacterium glutamicum ldhA gene, promoter region [online] https://www.ncbi.nlm.nih.gov/nuccore/AB191244.1/ 2009/07/22.
Toyoda K. et al., Molecular mechanism of SugR-mediated sugar-dependent expression of the ldhA gene encoding L-lactate dehydrogenase in Corynebacterium glutamicum. Applied Microbiology and Biotechnology, vol. 83, no. 2, 2009 May, pages 315-327.

Also Published As

Publication number Publication date
CN110709517B (zh) 2023-05-30
JP7018128B2 (ja) 2022-02-09
CA3073607A1 (en) 2019-09-12
BR112020004575A2 (pt) 2020-09-24
JP2021514602A (ja) 2021-06-17
AU2019232209A1 (en) 2020-03-05
WO2019172702A1 (ko) 2019-09-12
SG11202002185SA (en) 2020-04-29
AR114670A1 (es) 2020-09-30
BR112020004575B1 (pt) 2023-03-14
TW201940501A (zh) 2019-10-16
US11352608B2 (en) 2022-06-07
CA3073607C (en) 2023-07-04
US20210002654A1 (en) 2021-01-07
KR20190106815A (ko) 2019-09-18
AU2019232209B2 (en) 2023-04-06
CN110709517A (zh) 2020-01-17
EP3763819A1 (de) 2021-01-13
EP3763819A4 (de) 2021-12-22
ZA202001382B (en) 2021-05-26
KR102132342B1 (ko) 2020-07-10

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