TWI691335B - 用於治療腫瘤的抗pd-l1組合 - Google Patents

用於治療腫瘤的抗pd-l1組合 Download PDF

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TWI691335B
TWI691335B TW104122202A TW104122202A TWI691335B TW I691335 B TWI691335 B TW I691335B TW 104122202 A TW104122202 A TW 104122202A TW 104122202 A TW104122202 A TW 104122202A TW I691335 B TWI691335 B TW I691335B
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cancer
antibody
cells
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TW104122202A
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TW201628651A (zh
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立新 李
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英屬開曼群島商博笛生物科技有限公司
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Priority claimed from CN201410325480.9A external-priority patent/CN105233291A/zh
Priority claimed from CN201410440824.0A external-priority patent/CN105440135A/zh
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/39558—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
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    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2827—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against B7 molecules, e.g. CD80, CD86
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    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
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TW104122202A 2014-07-09 2015-07-08 用於治療腫瘤的抗pd-l1組合 TWI691335B (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
CN201410325480.9 2014-07-09
CN201410325480.9A CN105233291A (zh) 2014-07-09 2014-07-09 用于治疗癌症的联合治疗组合物和联合治疗方法
CN201410440824.0 2014-09-01
CN201410440824.0A CN105440135A (zh) 2014-09-01 2014-09-01 用于治疗肿瘤的抗-pd-l1结合物

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TW201628651A TW201628651A (zh) 2016-08-16
TWI691335B true TWI691335B (zh) 2020-04-21

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TW104122202A TWI691335B (zh) 2014-07-09 2015-07-08 用於治療腫瘤的抗pd-l1組合
TW108134121A TWI727427B (zh) 2014-07-09 2015-07-08 用於治療腫瘤的抗pd-1組合

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US (4) US20170114137A1 (enExample)
EP (2) EP4001311B1 (enExample)
JP (4) JP6760919B2 (enExample)
KR (1) KR102462743B1 (enExample)
CN (1) CN107074958A (enExample)
AR (1) AR132604A2 (enExample)
AU (3) AU2015286043B2 (enExample)
CA (1) CA2954446A1 (enExample)
DK (1) DK3166976T3 (enExample)
ES (1) ES2910446T3 (enExample)
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WO (1) WO2016004876A1 (enExample)

Families Citing this family (38)

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Publication number Priority date Publication date Assignee Title
RU2017132160A (ru) 2008-12-09 2019-02-08 Дженентек, Инк. Антитела к pd-l1 и их применение для усиления функции t-клеток
CN112587658A (zh) 2012-07-18 2021-04-02 博笛生物科技有限公司 癌症的靶向免疫治疗
US20170028079A1 (en) 2014-01-10 2017-02-02 Shanghai Birdie Biotech, Inc. Compounds and Compositions for Treating HER2 Positive Tumors
US10441654B2 (en) 2014-01-24 2019-10-15 Children's Hospital Of Eastern Ontario Research Institute Inc. SMC combination therapy for the treatment of cancer
CN106132439A (zh) 2014-03-31 2016-11-16 豪夫迈·罗氏有限公司 包含抗血管发生剂和ox40结合激动剂的组合疗法
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