US20100189651A1 - Modified antibody compositions, methods of making and using thereof - Google Patents

Modified antibody compositions, methods of making and using thereof Download PDF

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Publication number
US20100189651A1
US20100189651A1 US12/686,344 US68634410A US2010189651A1 US 20100189651 A1 US20100189651 A1 US 20100189651A1 US 68634410 A US68634410 A US 68634410A US 2010189651 A1 US2010189651 A1 US 2010189651A1
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US
United States
Prior art keywords
ab
target
mm
antibody
binding
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
US12/686,344
Inventor
Nancy E. Stagliano
James W. West
Kathryn Kamath
Paul H. Bessette
Frederick Gluck
Jason Sagert
Patrick Daugherty
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CytomX Therapeutics LLC
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CytomX Therapeutics LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to US14410509P priority Critical
Priority to US14411009P priority
Priority to US24944109P priority
Priority to US24941609P priority
Application filed by CytomX Therapeutics LLC filed Critical CytomX Therapeutics LLC
Priority to US12/686,344 priority patent/US20100189651A1/en
Assigned to CYTOMX THERAPEUTICS, LLC reassignment CYTOMX THERAPEUTICS, LLC ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: BESSETTE, PAUL H., DAUGHERTY, PATRICK, GLUCK, FREDERICK W., KAMATH, KATHRYN, SAGERT, JASON, STAGLIANO, NANCY E., WEST, JAMES W.
Publication of US20100189651A1 publication Critical patent/US20100189651A1/en
Assigned to CYTOMX THERAPEUTICS, INC. reassignment CYTOMX THERAPEUTICS, INC. CHANGE OF NAME (SEE DOCUMENT FOR DETAILS). Assignors: CYTOMX THERAPEUTICS, LLC
Assigned to CYTOMX THERAPEUTICS, INC. reassignment CYTOMX THERAPEUTICS, INC. ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: CYTOMX THERAPEUTICS, LLC
Application status is Abandoned legal-status Critical

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