MX2022006307A - Agonistas del receptor tipo toll 7 (tlr7). - Google Patents
Agonistas del receptor tipo toll 7 (tlr7).Info
- Publication number
- MX2022006307A MX2022006307A MX2022006307A MX2022006307A MX2022006307A MX 2022006307 A MX2022006307 A MX 2022006307A MX 2022006307 A MX2022006307 A MX 2022006307A MX 2022006307 A MX2022006307 A MX 2022006307A MX 2022006307 A MX2022006307 A MX 2022006307A
- Authority
- MX
- Mexico
- Prior art keywords
- tlr7 agonists
- tlr7
- agonists
- cancer
- diseases
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/16—Purine radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7076—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
- A61K31/708—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid having oxo groups directly attached to the purine ring system, e.g. guanosine, guanylic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Molecular Biology (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Engineering & Computer Science (AREA)
- Virology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Saccharide Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
La presente invención se refiere a agonistas de TLR7 según la fórmula I y su uso en el tratamiento de enfermedades como el cáncer y las enfermedades infecciosas (ver fórmula I).
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201962940622P | 2019-11-26 | 2019-11-26 | |
PCT/US2020/062344 WO2021108649A1 (en) | 2019-11-26 | 2020-11-25 | Tlr7 agonists |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2022006307A true MX2022006307A (es) | 2022-08-22 |
Family
ID=75974715
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2022006307A MX2022006307A (es) | 2019-11-26 | 2020-11-25 | Agonistas del receptor tipo toll 7 (tlr7). |
Country Status (17)
Country | Link |
---|---|
US (2) | US11692005B2 (es) |
EP (1) | EP4065155A4 (es) |
JP (1) | JP2023503996A (es) |
KR (1) | KR20220150879A (es) |
CN (1) | CN115427063A (es) |
AU (1) | AU2020391487A1 (es) |
BR (1) | BR112022010165A2 (es) |
CA (1) | CA3163093A1 (es) |
CL (1) | CL2022001377A1 (es) |
CO (1) | CO2022008835A2 (es) |
CR (1) | CR20220282A (es) |
EC (1) | ECSP22049906A (es) |
IL (1) | IL293293A (es) |
MX (1) | MX2022006307A (es) |
PE (1) | PE20221324A1 (es) |
TW (1) | TW202134240A (es) |
WO (1) | WO2021108649A1 (es) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN114917228B (zh) * | 2022-06-07 | 2023-09-26 | 广西中医药大学 | 一种用于预防性治疗狂犬病的药方及其制备方法与应用 |
Family Cites Families (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5476659A (en) | 1982-11-09 | 1995-12-19 | The Scripps Research Institute | Cancerous B cell treatment using substituted nucleoside derivatives |
US5011828A (en) | 1985-11-15 | 1991-04-30 | Michael Goodman | Immunostimulating guanine derivatives, compositions and methods |
US5136030A (en) | 1988-05-05 | 1992-08-04 | Scripps Clinic And Research Foundation | Immunostimulating guanine derivatives, compositions and methods |
US5093319A (en) | 1989-10-31 | 1992-03-03 | Pfizer Hospital Products Group, Inc. | Use of derivatives of chitin soluble in aqueous solutions for preventing adhesions |
AU5845594A (en) | 1992-11-13 | 1994-06-08 | Scripps Research Institute, The | Cancerous b cell treatment using substituted nucleoside derivatives |
ATE271063T1 (de) | 1996-10-16 | 2004-07-15 | Icn Pharmaceuticals | Purin-l-nukleoside, deren analoga und verwendungen |
TR200601784T2 (tr) | 1999-11-12 | 2007-01-22 | Pharmasset Ltd. | 2'-deoksi-L-nükleositlerin sentezi |
NZ521210A (en) | 2000-02-18 | 2004-11-26 | Shire Biochem Inc | Method for the treatment or prevention of flavivirus infections using nucleoside analogues |
PT1411954E (pt) | 2000-10-18 | 2011-03-16 | Pharmasset Inc | Nucleosídeos modificados para o tratamento de infecções virais e proliferação celular anormal |
CA2537450C (en) | 2003-09-05 | 2012-04-17 | Anadys Pharmaceuticals, Inc. | Administration of tlr7 ligands and prodrugs thereof for treatment of infection by hepatitis c virus |
TWI407956B (zh) | 2004-12-17 | 2013-09-11 | Anadys Pharmaceuticals Inc | 3,5-二取代和3,5,7-三取代-3H-唑并及3H-噻唑并〔4,5-d〕嘧啶-2-酮化合物及其前藥 |
AU2008286735A1 (en) | 2007-08-15 | 2009-02-19 | Idera Pharmaceuticals, Inc. | Toll like receptor modulators |
CA2732437C (en) | 2008-08-01 | 2017-11-21 | Ventirx Pharmaceuticals, Inc. | Toll-like receptor agonist formulations and their use |
WO2010111290A1 (en) | 2009-03-23 | 2010-09-30 | University Of Utah Research Foundation | Methods and compositions related to modified guanine bases for controlling off-target effects in rna interference |
CN104661683A (zh) | 2011-11-09 | 2015-05-27 | 埃森德生物制药有限公司 | 免疫调节缀合物 |
KR102462743B1 (ko) | 2014-07-09 | 2022-11-02 | 버디 바이오파마슈티칼즈, 인크. | 종양 치료용 항-pd-l1 조합 |
PL3230298T3 (pl) | 2014-12-08 | 2021-06-14 | F.Hoffmann-La Roche Ag | 3-podstawione związki 5-amino-6h-tiazolo[4,5-d]pirymidyno-2,7-dionowe do leczenia i profilaktyki zakażenia wirusowego |
SG10201912847QA (en) | 2015-03-16 | 2020-02-27 | Hoffmann La Roche | Combined treatment with a tlr7 agonist and an hbv capsid assembly inhibitor |
CN115554406A (zh) | 2016-01-07 | 2023-01-03 | 博笛生物科技有限公司 | 用于治疗肿瘤的抗-cd20组合 |
NZ755222A (en) | 2016-12-20 | 2022-07-01 | Astrazeneca Ab | Amino-triazolopyridine compounds and their use in treating cancer |
KR20210035095A (ko) | 2018-05-25 | 2021-03-31 | 프리뮨 테라퓨틱스, 인크. | Tlr7 효능제 |
-
2020
- 2020-11-25 CR CR20220282A patent/CR20220282A/es unknown
- 2020-11-25 JP JP2022530809A patent/JP2023503996A/ja active Pending
- 2020-11-25 MX MX2022006307A patent/MX2022006307A/es unknown
- 2020-11-25 BR BR112022010165A patent/BR112022010165A2/pt unknown
- 2020-11-25 US US17/104,808 patent/US11692005B2/en active Active
- 2020-11-25 KR KR1020227021204A patent/KR20220150879A/ko unknown
- 2020-11-25 WO PCT/US2020/062344 patent/WO2021108649A1/en unknown
- 2020-11-25 AU AU2020391487A patent/AU2020391487A1/en active Pending
- 2020-11-25 PE PE2022000859A patent/PE20221324A1/es unknown
- 2020-11-25 CN CN202080094510.3A patent/CN115427063A/zh active Pending
- 2020-11-25 TW TW109141359A patent/TW202134240A/zh unknown
- 2020-11-25 IL IL293293A patent/IL293293A/en unknown
- 2020-11-25 CA CA3163093A patent/CA3163093A1/en active Pending
- 2020-11-25 EP EP20894193.0A patent/EP4065155A4/en active Pending
-
2022
- 2022-05-25 CL CL2022001377A patent/CL2022001377A1/es unknown
- 2022-06-24 CO CONC2022/0008835A patent/CO2022008835A2/es unknown
- 2022-06-24 EC ECSENADI202249906A patent/ECSP22049906A/es unknown
-
2023
- 2023-06-30 US US18/345,903 patent/US20240116974A1/en active Pending
Also Published As
Publication number | Publication date |
---|---|
IL293293A (en) | 2022-07-01 |
ECSP22049906A (es) | 2022-07-29 |
BR112022010165A2 (pt) | 2022-08-09 |
US20210155652A1 (en) | 2021-05-27 |
JP2023503996A (ja) | 2023-02-01 |
KR20220150879A (ko) | 2022-11-11 |
TW202134240A (zh) | 2021-09-16 |
US11692005B2 (en) | 2023-07-04 |
CO2022008835A2 (es) | 2022-07-19 |
EP4065155A4 (en) | 2023-11-29 |
CN115427063A (zh) | 2022-12-02 |
CA3163093A1 (en) | 2021-06-03 |
CR20220282A (es) | 2022-11-28 |
EP4065155A1 (en) | 2022-10-05 |
PE20221324A1 (es) | 2022-09-09 |
WO2021108649A1 (en) | 2021-06-03 |
CL2022001377A1 (es) | 2023-04-10 |
US20240116974A1 (en) | 2024-04-11 |
AU2020391487A1 (en) | 2022-07-07 |
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