TWI669116B - 治療毛髮掉落及延緩皮膚老化之組合物及方法 - Google Patents

治療毛髮掉落及延緩皮膚老化之組合物及方法 Download PDF

Info

Publication number
TWI669116B
TWI669116B TW102125290A TW102125290A TWI669116B TW I669116 B TWI669116 B TW I669116B TW 102125290 A TW102125290 A TW 102125290A TW 102125290 A TW102125290 A TW 102125290A TW I669116 B TWI669116 B TW I669116B
Authority
TW
Taiwan
Prior art keywords
dihydromyricetin
hair
dihydromyricetin compound
compound
skin
Prior art date
Application number
TW102125290A
Other languages
English (en)
Chinese (zh)
Other versions
TW201408292A (zh
Inventor
史蒂芬 陳
Original Assignee
美商費托科技公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 美商費托科技公司 filed Critical 美商費托科技公司
Publication of TW201408292A publication Critical patent/TW201408292A/zh
Application granted granted Critical
Publication of TWI669116B publication Critical patent/TWI669116B/zh

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4973Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom
    • A61K8/498Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom having 6-membered rings or their condensed derivatives, e.g. coumarin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/72Rhamnaceae (Buckthorn family), e.g. buckthorn, chewstick or umbrella-tree
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/14Drugs for dermatological disorders for baldness or alopecia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/16Emollients or protectives, e.g. against radiation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/08Anti-ageing preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00Preparations for care of the hair
    • A61Q5/02Preparations for cleaning the hair
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00Preparations for care of the hair
    • A61Q5/12Preparations containing hair conditioners
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q7/00Preparations for affecting hair growth
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/22Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
    • C07D311/26Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3
    • C07D311/40Separation, e.g. from natural material; Purification
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/39Complex extraction schemes, e.g. fractionation or repeated extraction steps
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50Methods involving additional extraction steps
    • A61K2236/51Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/70Biological properties of the composition as a whole

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Dermatology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Birds (AREA)
  • Gerontology & Geriatric Medicine (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Medical Informatics (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Toxicology (AREA)
  • Cosmetics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
TW102125290A 2012-07-13 2013-07-15 治療毛髮掉落及延緩皮膚老化之組合物及方法 TWI669116B (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261671624P 2012-07-13 2012-07-13
US61/671,624 2012-07-13

Publications (2)

Publication Number Publication Date
TW201408292A TW201408292A (zh) 2014-03-01
TWI669116B true TWI669116B (zh) 2019-08-21

Family

ID=49916708

Family Applications (1)

Application Number Title Priority Date Filing Date
TW102125290A TWI669116B (zh) 2012-07-13 2013-07-15 治療毛髮掉落及延緩皮膚老化之組合物及方法

Country Status (11)

Country Link
US (3) US9789047B2 (enExample)
EP (1) EP2872133B1 (enExample)
JP (1) JP2015522083A (enExample)
CN (1) CN104797250A (enExample)
AU (1) AU2013289963B2 (enExample)
CA (1) CA2878914A1 (enExample)
ES (1) ES2733351T3 (enExample)
HU (1) HUE044816T2 (enExample)
MX (1) MX362488B (enExample)
TW (1) TWI669116B (enExample)
WO (1) WO2014012075A2 (enExample)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9789047B2 (en) 2012-07-13 2017-10-17 Phyto Tech Corp. Treating hair loss and delaying aging of skin
CN107427474A (zh) 2015-04-13 2017-12-01 株式会社Lg生活健康 含有调节神经递质释放的成分的可溶性微针
KR101803201B1 (ko) 2015-07-30 2017-11-30 성균관대학교산학협력단 미리세틴 유도체를 함유하는 snare 복합체 형성 억제용 조성물
WO2017018847A1 (ko) * 2015-07-30 2017-02-02 성균관대학교 산학협력단 미리세틴 유도체를 함유하는 snare 복합체 형성 억제용 조성물
CN105816507A (zh) * 2016-04-20 2016-08-03 中国科学院武汉植物园 一种白芨愈伤护肤制剂及其制备方法
CN107496241A (zh) * 2017-09-07 2017-12-22 师海全 一种含有文冠果生物活性成分的面膜的制备方法
CN107802562A (zh) * 2017-12-17 2018-03-16 周建福 一种洗发膏
GR1010117B (el) 2020-07-14 2021-11-08 Uni Pharma Κλεων Τσετης Φαρμακευτικα Εργαστηρια Αβεε, Διατροφικο συμπληρωμα για την απο του στοματος χορηγηση συνδυασμου διυδρομυρισετινης, χολινης και μιας ή περισσοτερων βιταμινων με αντιοξειδωτικη δραση, χρησιμων για τη φυσιολογικη λειτουργια του ηπατος
DE102020213959A1 (de) * 2020-11-06 2022-05-12 Beiersdorf Aktiengesellschaft Verwendung von Dihydromyricetin als epigenetischer Wirkstoff zur kosmetischen oder dermatologischen Hautpflege
JP7606737B2 (ja) 2020-12-09 2024-12-26 日本メナード化粧品株式会社 筋肉疲労改善剤
US12194021B2 (en) 2021-05-24 2025-01-14 University Of Southern California Modified herbal compositions for neuromodulation
KR102713600B1 (ko) * 2021-09-17 2024-10-07 주식회사 인트론바이오테크놀로지 보툴리눔 신경독소 대체 신규소재 및 이의 제조방법
CN114507205A (zh) * 2022-04-19 2022-05-17 北京佳福瑞生物科技有限公司 二氢杨梅素四氢吡咯复合物及其制备方法和应用
CN115177612A (zh) * 2022-08-01 2022-10-14 杭州凤禾植物科技有限公司 一种具有增发作用的组合物
CN115317392B (zh) * 2022-08-23 2023-10-24 广东领康日用品有限公司 一种控油去屑氨基酸洗发水及其制备方法
CN117243862A (zh) * 2023-08-09 2023-12-19 科丝美诗(中国)化妆品有限公司 一种莓茶提取物的制备方法、莓茶提取物及其应用

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101485655A (zh) * 2009-02-12 2009-07-22 华南理工大学 二氢杨梅素在制备防治肿瘤放化疗不良反应的药物的应用
EP2356980A2 (de) * 2009-11-27 2011-08-17 Beiersdorf Ag Verwendung von Dihydromyricetin gegen Altershaut
CN102225923A (zh) * 2011-04-14 2011-10-26 湖南朗林生物制品有限公司 藤茶中二氢杨梅素的制备方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS63208506A (ja) * 1987-02-24 1988-08-30 Nonogawa Shoji:Kk 化粧料
JP3597210B2 (ja) 1993-08-27 2004-12-02 花王株式会社 養毛料
JP5201771B2 (ja) 2001-04-06 2013-06-05 丸善製薬株式会社 テストステロン5α−レダクターゼ阻害剤、アンドロゲン受容体結合阻害剤、抗男性ホルモン剤及び養毛化粧料。
JP5614910B2 (ja) 2001-07-09 2014-10-29 丸善製薬株式会社 薬剤性肝炎治療剤
JP2004269430A (ja) * 2003-03-10 2004-09-30 Ichimaru Pharcos Co Ltd 毛髪処理用組成物及び損傷毛用毛髪化粧料
WO2009052518A2 (en) 2007-10-19 2009-04-23 Aspen Benefits Group, Llc Methods and compositions directed to reduction of facial hair hirsutism in females
US8309142B1 (en) * 2010-06-11 2012-11-13 RMV Trademarks, LLC Formulations and methods for preventing eyebrow hair loss
US9789047B2 (en) 2012-07-13 2017-10-17 Phyto Tech Corp. Treating hair loss and delaying aging of skin

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101485655A (zh) * 2009-02-12 2009-07-22 华南理工大学 二氢杨梅素在制备防治肿瘤放化疗不良反应的药物的应用
EP2356980A2 (de) * 2009-11-27 2011-08-17 Beiersdorf Ag Verwendung von Dihydromyricetin gegen Altershaut
CN102225923A (zh) * 2011-04-14 2011-10-26 湖南朗林生物制品有限公司 藤茶中二氢杨梅素的制备方法

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Towatari Keisuke et al.;"Polyphenols from the Heartwood of Cercidiphyllum japonicum and their Effects on Proliferation of Mouse Hair Epithelial Cells";Planta Medica,2002,pages 995-998. *

Also Published As

Publication number Publication date
WO2014012075A3 (en) 2014-03-06
TW201408292A (zh) 2014-03-01
US10426718B2 (en) 2019-10-01
US20170049674A1 (en) 2017-02-23
AU2013289963B2 (en) 2017-08-24
HK1210701A1 (en) 2016-05-06
EP2872133A2 (en) 2015-05-20
CN104797250A (zh) 2015-07-22
EP2872133A4 (en) 2016-01-20
AU2013289963A1 (en) 2015-01-29
US20170216176A1 (en) 2017-08-03
ES2733351T3 (es) 2019-11-28
EP2872133B1 (en) 2019-04-10
US9949912B2 (en) 2018-04-24
HUE044816T2 (hu) 2019-11-28
CA2878914A1 (en) 2014-01-16
MX2015000365A (es) 2015-07-14
JP2015522083A (ja) 2015-08-03
US20170354582A9 (en) 2017-12-14
WO2014012075A2 (en) 2014-01-16
US20150209256A1 (en) 2015-07-30
US9789047B2 (en) 2017-10-17
MX362488B (es) 2019-01-21

Similar Documents

Publication Publication Date Title
TWI669116B (zh) 治療毛髮掉落及延緩皮膚老化之組合物及方法
JPH06505750A (ja) 育毛刺激または抜け毛を抑制するために特に意図されたオキシアカンチン含有化粧用または製薬用、特に皮膚病用組成物
JP3409165B2 (ja) 養毛剤とその製造方法
JP6338107B2 (ja) 皮膚バリア機能改善剤、細胞間接着構造の形成促進剤、タイトジャンクション形成促進剤及びtrpv4遺伝子の発現亢進剤
JP6173362B2 (ja) 皮膚バリア機能改善剤、細胞間接着構造の形成促進剤、タイトジャンクション形成促進剤、TRPV4活性化剤、細胞内Ca濃度上昇亢進剤及び皮脂産生促進剤
JP3998085B2 (ja) ヒアルロン酸量増加促進剤
JP6723979B2 (ja) しわ改善剤
JP2002284648A (ja) 育毛剤組成物
CA3214570A1 (en) Hair serum and supplement
KR100702329B1 (ko) 백굴채 추출물을 유효성분으로 함유하는 5α-리덕테이즈활성 억제용 조성물 및 피지 분비 억제용 화장료 조성물
JP2010150237A (ja) セラミド産生促進剤、並びに該セラミド産生促進剤を用いた医薬品組成物、皮膚外用剤、化粧料組成物、及び化粧料
JP2022006397A (ja) バリア機能亢進剤
JP7680990B2 (ja) 肌のくすみ改善剤
JP5000964B2 (ja) テストステロン5α−リダクターゼ活性阻害剤、アンドロゲンレセプター拮抗剤、その用途、及びアンドロゲン活性発現の抑制方法
HK1210701B (en) Compositions and methods for treating hair loss
KR20140096771A (ko) 플라티코딘 d를 함유하는 도라지 추출물을 유효성분으로 포함하는 접촉성 피부염 예방 또는 치료용 약학적 조성물
KR20080032673A (ko) 패모 추출물을 유효성분으로 함유하는 피지 분비 억제용 화장료 조성물
JP6291466B2 (ja) 皮膚バリア機能改善剤、細胞間接着構造の形成促進剤、タイトジャンクション形成促進剤、TRPV4活性化剤、細胞内Ca濃度上昇亢進剤及び皮脂産生促進剤
WO2016164997A1 (pt) Composições para formulação cosmética de hidratação prolongada compreendendo manteiga de ucuuba com elevada concentração de ácido mirístico, bem como uso da dita formulação para preparação de um produto cosmético com alto poder hidrante e kit
JP2020073585A (ja) しわ改善剤