TWI566771B - 視網膜疾病的預防、改善或治療劑 - Google Patents

視網膜疾病的預防、改善或治療劑 Download PDF

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Publication number
TWI566771B
TWI566771B TW102106505A TW102106505A TWI566771B TW I566771 B TWI566771 B TW I566771B TW 102106505 A TW102106505 A TW 102106505A TW 102106505 A TW102106505 A TW 102106505A TW I566771 B TWI566771 B TW I566771B
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TW
Taiwan
Prior art keywords
gga
geranylgeranylacetone
weight
retinal
mixture
Prior art date
Application number
TW102106505A
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English (en)
Chinese (zh)
Other versions
TW201338771A (zh
Inventor
黑瀨孝弘
宮野貴之
加藤萬里代
高井良宏
Original Assignee
樂敦製藥股份有限公司
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Publication date
Application filed by 樂敦製藥股份有限公司 filed Critical 樂敦製藥股份有限公司
Publication of TW201338771A publication Critical patent/TW201338771A/zh
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Publication of TWI566771B publication Critical patent/TWI566771B/zh

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
    • A61K31/121—Ketones acyclic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Inorganic Chemistry (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
TW102106505A 2012-02-27 2013-02-25 視網膜疾病的預防、改善或治療劑 TWI566771B (zh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2012040803 2012-02-27

Publications (2)

Publication Number Publication Date
TW201338771A TW201338771A (zh) 2013-10-01
TWI566771B true TWI566771B (zh) 2017-01-21

Family

ID=49082513

Family Applications (1)

Application Number Title Priority Date Filing Date
TW102106505A TWI566771B (zh) 2012-02-27 2013-02-25 視網膜疾病的預防、改善或治療劑

Country Status (6)

Country Link
US (2) US20130303625A1 (enExample)
JP (2) JP5345744B1 (enExample)
CN (1) CN104136015B (enExample)
IN (1) IN2014MN01552A (enExample)
TW (1) TWI566771B (enExample)
WO (1) WO2013129315A1 (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IN2014MN01552A (enExample) * 2012-02-27 2015-05-08 Rohto Pharma
WO2014129466A1 (ja) * 2013-02-19 2014-08-28 ロート製薬株式会社 網膜疾患の予防、改善、又は治療用粘膜適用剤
TW201542198A (zh) * 2013-08-26 2015-11-16 Rohto Pharma 視網膜疾病之預防、改善或治療劑
WO2015129809A1 (ja) * 2014-02-28 2015-09-03 国立大学法人京都大学 虚血性眼疾患の処置用の医薬組成物
CN108998006B (zh) * 2018-07-20 2021-06-08 合肥工业大学 一种环境友好的应变响应型荧光超分子材料及其制备方法
ES2970996T3 (es) * 2018-10-19 2024-06-03 Medicinova Inc Tratamiento de la lesión macular asociada a la esclerosis múltiple con ibudilast
CN109470534B (zh) * 2018-11-12 2021-05-25 山东骏腾医疗科技有限公司 一种病理组织透明脱蜡液及其制备方法
CN109675038A (zh) * 2019-02-01 2019-04-26 杭州赫尔斯科技有限公司 增强低浓度阿托品类药物安全性和临床疗效的组合物
CN119792302B (zh) * 2025-03-14 2025-06-24 山东师范大学 前列腺素e2在制备治疗蓝光暴露引发的视网膜损伤的药物中的应用

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH06192073A (ja) * 1992-12-24 1994-07-12 Eisai Co Ltd 細胞分化誘導剤
JPH08133967A (ja) * 1994-11-02 1996-05-28 Eisai Co Ltd ドライアイ治療剤

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3560072B2 (ja) 1994-05-20 2004-09-02 エーザイ株式会社 外用基剤
JP2000319170A (ja) 1999-03-05 2000-11-21 Eisai Co Ltd テプレノン含有点眼剤
US20050009772A1 (en) * 2003-05-06 2005-01-13 The Regents Of The University Of California Methods and compositions for the treatment of glaucoma and other retinal diseases
BRPI0615974A2 (pt) * 2005-07-27 2011-05-31 University Of Florida Research Foundation, Inc., uso de choque térmico para tratar uma doença ocular em um indivìduo, método para recrutar uma célula-tronco para um tecido ocular de um indivìduo com necessidade da mesma, uso de choque térmico para tratar uma doença ou um distúrbio ocular em um indivìduo com necessidade do mesmo, uso de choque térmico para regenerar a retina em um indivìduo com necessidade do mesmo, uso de choque térmico para reparar os danos ao epitélio pgmentar da retina em um indivìduo com necessidade do mesmo, uso de choque térmico para tratar a degeneração macular em um indivìduo com necessidade do mesmo, composição farmacêutica para o recrutamento de células-tronco, composição farmacêutica para recrutamento de células-tronco em um tecido ocular, kit e método para identificar um agente que aumenta o recrutamento de células-tronco em um tecido ocular
CN101267779A (zh) 2005-07-27 2008-09-17 福罗里达大学研究基金会有限公司 使用热休克治疗眼睛疾病
EP2611765A4 (en) 2010-09-01 2014-06-11 Coyote Pharmaceuticals Inc METHODS OF TREATING NEURODEGENERATIVE DISEASES
IN2014MN01552A (enExample) 2012-02-27 2015-05-08 Rohto Pharma

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH06192073A (ja) * 1992-12-24 1994-07-12 Eisai Co Ltd 細胞分化誘導剤
JPH08133967A (ja) * 1994-11-02 1996-05-28 Eisai Co Ltd ドライアイ治療剤

Also Published As

Publication number Publication date
WO2013129315A1 (ja) 2013-09-06
JP5345744B1 (ja) 2013-11-20
IN2014MN01552A (enExample) 2015-05-08
US20130303625A1 (en) 2013-11-14
HK1200111A1 (en) 2015-07-31
CN104136015A (zh) 2014-11-05
JP2013213049A (ja) 2013-10-17
US9724312B2 (en) 2017-08-08
CN104136015B (zh) 2016-11-09
JPWO2013129315A1 (ja) 2015-07-30
US20140128475A1 (en) 2014-05-08
TW201338771A (zh) 2013-10-01

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