CN104136015B - 视网膜疾病的预防、改善或治疗剂 - Google Patents

视网膜疾病的预防、改善或治疗剂 Download PDF

Info

Publication number
CN104136015B
CN104136015B CN201380011312.6A CN201380011312A CN104136015B CN 104136015 B CN104136015 B CN 104136015B CN 201380011312 A CN201380011312 A CN 201380011312A CN 104136015 B CN104136015 B CN 104136015B
Authority
CN
China
Prior art keywords
gga
weight
acetone
retinal
geranyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN201380011312.6A
Other languages
English (en)
Chinese (zh)
Other versions
CN104136015A (zh
Inventor
黑濑孝弘
宫野贵之
加藤万里代
高井良宏
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Rohto Pharmaceutical Co Ltd
Original Assignee
Rohto Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rohto Pharmaceutical Co Ltd filed Critical Rohto Pharmaceutical Co Ltd
Publication of CN104136015A publication Critical patent/CN104136015A/zh
Application granted granted Critical
Publication of CN104136015B publication Critical patent/CN104136015B/zh
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
    • A61K31/121—Ketones acyclic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Inorganic Chemistry (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CN201380011312.6A 2012-02-27 2013-02-25 视网膜疾病的预防、改善或治疗剂 Expired - Fee Related CN104136015B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2012040803 2012-02-27
JP2012-040803 2012-02-27
PCT/JP2013/054774 WO2013129315A1 (ja) 2012-02-27 2013-02-25 網膜疾患の予防、改善、又は治療剤

Publications (2)

Publication Number Publication Date
CN104136015A CN104136015A (zh) 2014-11-05
CN104136015B true CN104136015B (zh) 2016-11-09

Family

ID=49082513

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201380011312.6A Expired - Fee Related CN104136015B (zh) 2012-02-27 2013-02-25 视网膜疾病的预防、改善或治疗剂

Country Status (6)

Country Link
US (2) US20130303625A1 (enExample)
JP (2) JP5345744B1 (enExample)
CN (1) CN104136015B (enExample)
IN (1) IN2014MN01552A (enExample)
TW (1) TWI566771B (enExample)
WO (1) WO2013129315A1 (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IN2014MN01552A (enExample) * 2012-02-27 2015-05-08 Rohto Pharma
WO2014129466A1 (ja) * 2013-02-19 2014-08-28 ロート製薬株式会社 網膜疾患の予防、改善、又は治療用粘膜適用剤
TW201542198A (zh) * 2013-08-26 2015-11-16 Rohto Pharma 視網膜疾病之預防、改善或治療劑
WO2015129809A1 (ja) * 2014-02-28 2015-09-03 国立大学法人京都大学 虚血性眼疾患の処置用の医薬組成物
CN108998006B (zh) * 2018-07-20 2021-06-08 合肥工业大学 一种环境友好的应变响应型荧光超分子材料及其制备方法
ES2970996T3 (es) * 2018-10-19 2024-06-03 Medicinova Inc Tratamiento de la lesión macular asociada a la esclerosis múltiple con ibudilast
CN109470534B (zh) * 2018-11-12 2021-05-25 山东骏腾医疗科技有限公司 一种病理组织透明脱蜡液及其制备方法
CN109675038A (zh) * 2019-02-01 2019-04-26 杭州赫尔斯科技有限公司 增强低浓度阿托品类药物安全性和临床疗效的组合物
CN119792302B (zh) * 2025-03-14 2025-06-24 山东师范大学 前列腺素e2在制备治疗蓝光暴露引发的视网膜损伤的药物中的应用

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050009772A1 (en) * 2003-05-06 2005-01-13 The Regents Of The University Of California Methods and compositions for the treatment of glaucoma and other retinal diseases

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH06192073A (ja) * 1992-12-24 1994-07-12 Eisai Co Ltd 細胞分化誘導剤
JP3560072B2 (ja) 1994-05-20 2004-09-02 エーザイ株式会社 外用基剤
JPH08133967A (ja) * 1994-11-02 1996-05-28 Eisai Co Ltd ドライアイ治療剤
JP2000319170A (ja) 1999-03-05 2000-11-21 Eisai Co Ltd テプレノン含有点眼剤
BRPI0615974A2 (pt) * 2005-07-27 2011-05-31 University Of Florida Research Foundation, Inc., uso de choque térmico para tratar uma doença ocular em um indivìduo, método para recrutar uma célula-tronco para um tecido ocular de um indivìduo com necessidade da mesma, uso de choque térmico para tratar uma doença ou um distúrbio ocular em um indivìduo com necessidade do mesmo, uso de choque térmico para regenerar a retina em um indivìduo com necessidade do mesmo, uso de choque térmico para reparar os danos ao epitélio pgmentar da retina em um indivìduo com necessidade do mesmo, uso de choque térmico para tratar a degeneração macular em um indivìduo com necessidade do mesmo, composição farmacêutica para o recrutamento de células-tronco, composição farmacêutica para recrutamento de células-tronco em um tecido ocular, kit e método para identificar um agente que aumenta o recrutamento de células-tronco em um tecido ocular
CN101267779A (zh) 2005-07-27 2008-09-17 福罗里达大学研究基金会有限公司 使用热休克治疗眼睛疾病
EP2611765A4 (en) 2010-09-01 2014-06-11 Coyote Pharmaceuticals Inc METHODS OF TREATING NEURODEGENERATIVE DISEASES
IN2014MN01552A (enExample) 2012-02-27 2015-05-08 Rohto Pharma

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050009772A1 (en) * 2003-05-06 2005-01-13 The Regents Of The University Of California Methods and compositions for the treatment of glaucoma and other retinal diseases

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Cytoprotective Effects of Geranylgeranylacetone against Retinal Photooxidative Damage;Masaki Tanito等;《The Journal of Neuroscience》;20050302;第25卷(第9期);第2396-2404页 *

Also Published As

Publication number Publication date
TWI566771B (zh) 2017-01-21
WO2013129315A1 (ja) 2013-09-06
JP5345744B1 (ja) 2013-11-20
IN2014MN01552A (enExample) 2015-05-08
US20130303625A1 (en) 2013-11-14
HK1200111A1 (en) 2015-07-31
CN104136015A (zh) 2014-11-05
JP2013213049A (ja) 2013-10-17
US9724312B2 (en) 2017-08-08
JPWO2013129315A1 (ja) 2015-07-30
US20140128475A1 (en) 2014-05-08
TW201338771A (zh) 2013-10-01

Similar Documents

Publication Publication Date Title
TWI566771B (zh) 視網膜疾病的預防、改善或治療劑
TWI565464B (zh) 眼科用組成物
JP5358748B1 (ja) ゲラニルゲラニルアセトンを含む眼科用組成物
JP5345745B1 (ja) 眼科用組成物
TW201542197A (zh) 眼科用組成物
TW201524499A (zh) 眼科用組成物
TW201542196A (zh) 眼科用製劑
JP5687395B2 (ja) 網膜疾患の予防、改善、又は治療用粘膜適用剤
JP5483513B1 (ja) 網膜疾患の予防、改善、又は治療用粘膜適用剤
HK1200111B (en) Prophylactic, ameliorating or therapeutic agent for retinal diseases
TW201542198A (zh) 視網膜疾病之預防、改善或治療劑

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
REG Reference to a national code

Ref country code: HK

Ref legal event code: DE

Ref document number: 1200111

Country of ref document: HK

C14 Grant of patent or utility model
GR01 Patent grant
REG Reference to a national code

Ref country code: HK

Ref legal event code: GR

Ref document number: 1200111

Country of ref document: HK

CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20161109

Termination date: 20210225

CF01 Termination of patent right due to non-payment of annual fee