TWI562776B - Pharmaceutical composition and uses thereof - Google Patents

Pharmaceutical composition and uses thereof

Info

Publication number
TWI562776B
TWI562776B TW103116020A TW103116020A TWI562776B TW I562776 B TWI562776 B TW I562776B TW 103116020 A TW103116020 A TW 103116020A TW 103116020 A TW103116020 A TW 103116020A TW I562776 B TWI562776 B TW I562776B
Authority
TW
Taiwan
Prior art keywords
pharmaceutical composition
pharmaceutical
composition
Prior art date
Application number
TW103116020A
Other languages
English (en)
Other versions
TW201446245A (zh
Inventor
Pei-Chang Wu
Jia-Ling Cai
Jue-Tan Chen
Original Assignee
Wu Pei Xun
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wu Pei Xun filed Critical Wu Pei Xun
Publication of TW201446245A publication Critical patent/TW201446245A/zh
Application granted granted Critical
Publication of TWI562776B publication Critical patent/TWI562776B/zh

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/196—Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A61K31/405—Indole-alkanecarboxylic acids; Derivatives thereof, e.g. tryptophan, indomethacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/407—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/10—Ophthalmic agents for accommodation disorders, e.g. myopia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
TW103116020A 2013-05-06 2014-05-06 Pharmaceutical composition and uses thereof TWI562776B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201361819709P 2013-05-06 2013-05-06

Publications (2)

Publication Number Publication Date
TW201446245A TW201446245A (zh) 2014-12-16
TWI562776B true TWI562776B (en) 2016-12-21

Family

ID=51867665

Family Applications (2)

Application Number Title Priority Date Filing Date
TW105126589A TWI617306B (zh) 2013-05-06 2014-05-06 醫藥組成物及其用途
TW103116020A TWI562776B (en) 2013-05-06 2014-05-06 Pharmaceutical composition and uses thereof

Family Applications Before (1)

Application Number Title Priority Date Filing Date
TW105126589A TWI617306B (zh) 2013-05-06 2014-05-06 醫藥組成物及其用途

Country Status (11)

Country Link
US (3) US20160067238A1 (zh)
EP (1) EP2994197B1 (zh)
JP (2) JP6208332B2 (zh)
KR (2) KR20160004288A (zh)
CN (1) CN105555363B (zh)
CA (2) CA2911298C (zh)
ES (1) ES2871116T3 (zh)
HK (1) HK1219691A1 (zh)
SG (1) SG11201508453YA (zh)
TW (2) TWI617306B (zh)
WO (1) WO2014182620A1 (zh)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9421199B2 (en) 2014-06-24 2016-08-23 Sydnexis, Inc. Ophthalmic composition
US11382909B2 (en) 2014-09-05 2022-07-12 Sydnexis, Inc. Ophthalmic composition
AU2018265257B2 (en) 2017-05-11 2020-08-06 Vyluma Inc. Atropine pharmaceutical compositions
TWI822690B (zh) 2017-07-20 2023-11-21 中國大陸商盛元醫藥廣州有限公司 用於治療近視之組合物及方法
JP7370329B2 (ja) 2018-01-17 2023-10-27 アイノビア，インコーポレイティド 液滴のマイクロドーズストリームとして眼にアトロピンを送達するための方法および装置

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0465234A1 (en) * 1990-07-03 1992-01-08 McNEIL-PPC, INC. Pharmaceutical compositions and methods for alleviating gastrointestinal distress symptoms induced by nonsteroidal anti-inflammatory drugs
WO2001095913A1 (en) * 2000-06-13 2001-12-20 Synphora Ab Methods and compositions for the prevention of myopia
US20070254914A1 (en) * 2006-05-01 2007-11-01 Non-Profit Organization Chang Gung Memorial Hospital Low-concentration atropine solution for preventing myopia progression and preparing method thereof

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JPH01226313A (ja) * 1988-03-07 1989-09-11 Toyota Motor Corp 樹脂成形品の製造方法
US4938949A (en) 1988-09-12 1990-07-03 University Of New York Treatment of damaged bone marrow and dosage units therefor
JP2000026313A (ja) * 1998-05-06 2000-01-25 Hokuriku Seiyaku Co Ltd 消化管運動抑制剤
ITMI20010733A1 (it) 2001-04-05 2002-10-05 Recordati Chem Pharm Uso di inibitori dell'isoenzina cox-2 per il trattamento dell'incontinenza urinaria
CN103143022A (zh) * 2002-07-30 2013-06-12 奥默罗斯公司 眼科冲洗液及方法
ES2341240T3 (es) 2002-12-13 2010-06-17 Warner-Lambert Company Llc Ligando alfa-2-delta para tratar los sintomas del tracto urinario inferior.
KR20070083941A (ko) 2004-10-04 2007-08-24 큐엘티 유에스에이, 인코포레이티드 중합체 전달 조성을 갖는 눈 전달
CN1302812C (zh) 2004-11-30 2007-03-07 中国海洋大学 含海藻糖和玻璃酸的眼部用药传递系统及其制备方法
KR20100087291A (ko) 2007-09-25 2010-08-04 아보트 러보러터리즈 케모카인 수용체 길항제로서의 옥타하이드로펜탈렌 화합물
BRPI0908502A2 (pt) * 2008-02-21 2017-05-23 Ista Pharmaceuticals aines oftálmicos como adjuvantes
US9046699B2 (en) 2012-03-13 2015-06-02 Johnson & Johnson Vision Care, Inc. Dynamic fluid zones in contact lenses
JP6360040B2 (ja) * 2012-05-03 2018-07-18 カラ ファーマシューティカルズ インコーポレイテッド 粘液浸透性被覆粒子、組成物、医薬組成物、医薬製剤、及びそれらの形成方法
CN104394856A (zh) 2012-05-21 2015-03-04 Dcb美国公司 以斑马鱼模型进行药物筛选的方法及筛选所得药物
US9827250B2 (en) * 2012-07-31 2017-11-28 Johnson & Johnson Vision Care, Inc. Lens incorporating myopia control optics and muscarinic agents

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0465234A1 (en) * 1990-07-03 1992-01-08 McNEIL-PPC, INC. Pharmaceutical compositions and methods for alleviating gastrointestinal distress symptoms induced by nonsteroidal anti-inflammatory drugs
WO2001095913A1 (en) * 2000-06-13 2001-12-20 Synphora Ab Methods and compositions for the prevention of myopia
US20070254914A1 (en) * 2006-05-01 2007-11-01 Non-Profit Organization Chang Gung Memorial Hospital Low-concentration atropine solution for preventing myopia progression and preparing method thereof

Also Published As

Publication number Publication date
TW201446245A (zh) 2014-12-16
US10548887B2 (en) 2020-02-04
CN105555363B (zh) 2019-03-12
US20160067238A1 (en) 2016-03-10
CA2911298A1 (en) 2014-11-13
KR20160004288A (ko) 2016-01-12
EP2994197A1 (en) 2016-03-16
CA3050457A1 (en) 2014-11-13
US20200113890A1 (en) 2020-04-16
JP6208332B2 (ja) 2017-10-04
CN105555363A (zh) 2016-05-04
WO2014182620A1 (en) 2014-11-13
JP2016518410A (ja) 2016-06-23
CA3050457C (en) 2021-05-25
EP2994197B1 (en) 2021-04-28
JP6450814B2 (ja) 2019-01-09
US20180311227A1 (en) 2018-11-01
HK1219691A1 (zh) 2017-04-13
TW201641105A (zh) 2016-12-01
ES2871116T3 (es) 2021-10-28
TWI617306B (zh) 2018-03-11
US10888556B2 (en) 2021-01-12
EP2994197A4 (en) 2016-12-28
SG11201508453YA (en) 2015-11-27
KR102027663B1 (ko) 2019-10-01
CA2911298C (en) 2019-09-17
KR20170094552A (ko) 2017-08-18
JP2018008991A (ja) 2018-01-18

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