TWI535440B - 包括吲哚化合物之醫藥組成物 - Google Patents

包括吲哚化合物之醫藥組成物 Download PDF

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TWI535440B
TWI535440B TW102147720A TW102147720A TWI535440B TW I535440 B TWI535440 B TW I535440B TW 102147720 A TW102147720 A TW 102147720A TW 102147720 A TW102147720 A TW 102147720A TW I535440 B TWI535440 B TW I535440B
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Taiwan
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alkyl
cells
formula
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TW102147720A
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TW201414473A (zh
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金淳河
金亨秦
朴喜戌
具善領
郭孝信
朴斗喜
金孝洙
趙顯宰
金志炫
金珠英
朴光敏
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Lg生命科學有限公司
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    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/541Non-condensed thiazines containing further heterocyclic rings
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    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404Indoles, e.g. pindolol
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    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/41641,3-Diazoles
    • A61K31/41841,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
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    • A61K31/33Heterocyclic compounds
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    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425Thiazoles
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    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
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    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4906Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom
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    • A61K8/492Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having five membered rings, e.g. pyrrolidone carboxylic acid having condensed rings, e.g. indol
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    • C07D417/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
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    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
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    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
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  • Cardiology (AREA)
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  • Rheumatology (AREA)
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  • Dermatology (AREA)
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  • Birds (AREA)
  • Pain & Pain Management (AREA)
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TW102147720A 2009-10-26 2010-10-22 包括吲哚化合物之醫藥組成物 TWI535440B (zh)

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Application Number Priority Date Filing Date Title
KR20090101978 2009-10-26
KR20100098511 2010-10-08

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TW201414473A TW201414473A (zh) 2014-04-16
TWI535440B true TWI535440B (zh) 2016-06-01

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TW102147720A TWI535440B (zh) 2009-10-26 2010-10-22 包括吲哚化合物之醫藥組成物
TW099136045A TW201119651A (en) 2009-10-26 2010-10-22 Pharmaceutical composition comprising indole compound

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US (2) US20120214804A1 (https=)
EP (1) EP2493469A4 (https=)
JP (1) JP5820813B2 (https=)
KR (1) KR101325272B1 (https=)
CN (1) CN102596198B (https=)
AR (1) AR078775A1 (https=)
BR (1) BR112012009894A2 (https=)
MX (1) MX338807B (https=)
RU (1) RU2557243C2 (https=)
TR (1) TR201204895T1 (https=)
TW (2) TWI535440B (https=)
WO (1) WO2011052950A2 (https=)

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KR101304772B1 (ko) * 2011-04-11 2013-09-05 인제대학교 산학협력단 NecroX―5를 유효성분으로 포함하는 미토콘드리아 기능 조절용 조성물
WO2013115457A1 (ko) * 2012-01-31 2013-08-08 인제대학교 산학협력단 NecroX를 함유하는 암 전이 억제용 조성물
KR101400346B1 (ko) * 2012-01-31 2014-05-30 인제대학교 산학협력단 NecroX를 함유하는 암 전이 억제용 조성물
RU2664696C2 (ru) * 2014-04-18 2018-08-21 ЭлДжи КЕМ, ЛТД. Композиция для предотвращения или лечения жировых болезней печени
CA2953387C (en) 2014-06-30 2023-11-28 The Regents Of The University Of California Ketobutyrate compounds and compositions for treating age-related symptoms and diseases
KR101633703B1 (ko) * 2014-12-30 2016-06-27 한국원자력의학원 necro X-5를 유효성분으로 포함하는 방사선 조사에 의한 세포손상 예방 또는 치료용 조성물
CN107434819B (zh) * 2017-02-15 2020-03-17 河北医科大学第二医院 吲哚-tempo缀合物及其在保护远隔器官对抗缺血再灌注损伤中的用途
CN115109116A (zh) * 2017-08-17 2022-09-27 凯瑞康宁生物工程(武汉)有限公司 活性氧清除剂衍生物的制备及用途
WO2019041361A1 (en) 2017-09-04 2019-03-07 Xw Laboratories, Inc. PREPARATION AND USE OF A REACTIVE OXYGEN SPECIES TRAPPER
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