TWI421493B - 色層分析用管柱及其製造方法與分析裝置 - Google Patents
色層分析用管柱及其製造方法與分析裝置 Download PDFInfo
- Publication number
- TWI421493B TWI421493B TW100106052A TW100106052A TWI421493B TW I421493 B TWI421493 B TW I421493B TW 100106052 A TW100106052 A TW 100106052A TW 100106052 A TW100106052 A TW 100106052A TW I421493 B TWI421493 B TW I421493B
- Authority
- TW
- Taiwan
- Prior art keywords
- column
- side wall
- analysis
- portions
- flow path
- Prior art date
Links
- 238000004458 analytical method Methods 0.000 title claims description 88
- 238000004519 manufacturing process Methods 0.000 title claims description 19
- 238000004587 chromatography analysis Methods 0.000 title claims description 5
- 230000005526 G1 to G0 transition Effects 0.000 claims description 7
- 238000000034 method Methods 0.000 claims description 7
- 238000011144 upstream manufacturing Methods 0.000 claims description 7
- 238000005530 etching Methods 0.000 claims description 6
- 238000005520 cutting process Methods 0.000 claims description 2
- 230000000873 masking effect Effects 0.000 claims description 2
- 238000009826 distribution Methods 0.000 description 17
- 238000009792 diffusion process Methods 0.000 description 6
- 238000001514 detection method Methods 0.000 description 3
- 239000004065 semiconductor Substances 0.000 description 3
- 238000000926 separation method Methods 0.000 description 3
- 238000004364 calculation method Methods 0.000 description 2
- 238000007385 chemical modification Methods 0.000 description 2
- 238000005229 chemical vapour deposition Methods 0.000 description 2
- 239000002245 particle Substances 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 241000270295 Serpentes Species 0.000 description 1
- 239000013060 biological fluid Substances 0.000 description 1
- 229910052797 bismuth Inorganic materials 0.000 description 1
- JCXGWMGPZLAOME-UHFFFAOYSA-N bismuth atom Chemical compound [Bi] JCXGWMGPZLAOME-UHFFFAOYSA-N 0.000 description 1
- 230000000052 comparative effect Effects 0.000 description 1
- 230000007423 decrease Effects 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 230000012447 hatching Effects 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 238000001459 lithography Methods 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 238000005086 pumping Methods 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/60—Construction of the column
- G01N30/6095—Micromachined or nanomachined, e.g. micro- or nanosize
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502761—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip specially adapted for handling suspended solids or molecules independently from the bulk fluid flow, e.g. for trapping or sorting beads, for physically stretching molecules
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
- B01L2400/0487—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/08—Regulating or influencing the flow resistance
- B01L2400/084—Passive control of flow resistance
- B01L2400/086—Passive control of flow resistance using baffles or other fixed flow obstructions
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- General Health & Medical Sciences (AREA)
- Clinical Laboratory Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Hematology (AREA)
- Fluid Mechanics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Nanotechnology (AREA)
- Dispersion Chemistry (AREA)
- Biochemistry (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Treatment Of Liquids With Adsorbents In General (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2010040077A JP2011174856A (ja) | 2010-02-25 | 2010-02-25 | クロマトグラフィー用カラム、その製造方法、および分析装置 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| TW201142281A TW201142281A (en) | 2011-12-01 |
| TWI421493B true TWI421493B (zh) | 2014-01-01 |
Family
ID=44506425
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TW100106052A TWI421493B (zh) | 2010-02-25 | 2011-02-23 | 色層分析用管柱及其製造方法與分析裝置 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20120318049A1 (enExample) |
| EP (1) | EP2541245A4 (enExample) |
| JP (1) | JP2011174856A (enExample) |
| CN (1) | CN102812354A (enExample) |
| TW (1) | TWI421493B (enExample) |
| WO (1) | WO2011104990A1 (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE1022314B1 (nl) * | 2013-02-05 | 2016-03-15 | PharmaFluidics N.V. | Chemische reactor inrichting |
| US10073068B2 (en) | 2013-09-18 | 2018-09-11 | Agilent Technologies, Inc. | Liquid chromatography columns with structured walls |
| BE1024344B1 (nl) * | 2016-07-04 | 2018-02-02 | PharmaFluidics N.V. | Productie van chemische reactoren |
| CN108333283B (zh) * | 2017-01-20 | 2024-07-19 | 中国科学院上海微系统与信息技术研究所 | 一种含有流线型椭圆微柱阵列的微色谱柱及其制备方法 |
| BE1026910B1 (nl) * | 2018-12-21 | 2020-07-22 | Pharmafluidics N V | Chemische reactoren |
| BE1028976B1 (nl) * | 2020-12-30 | 2022-08-01 | Pharmafluidics N V | Pilaarstructuren |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1720438A (zh) * | 2002-11-29 | 2006-01-11 | 日本电气株式会社 | 分离设备和分离方法 |
| TW200831173A (en) * | 2006-08-14 | 2008-08-01 | Tokyo Electron Ltd | Column for chromatography and its manufacturing method |
| WO2009128294A1 (ja) * | 2008-04-19 | 2009-10-22 | ブラザー工業株式会社 | 検査対象受体及び当該検査対象受体を備えた検査装置 |
| US20090314065A1 (en) * | 2007-08-24 | 2009-12-24 | Tokyo Electron Limited | Chromatography detector |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH07120450A (ja) * | 1993-10-22 | 1995-05-12 | Sumika Bunseki Center:Kk | 多孔質体クロマトグラフィー用カラム |
| US6156273A (en) * | 1997-05-27 | 2000-12-05 | Purdue Research Corporation | Separation columns and methods for manufacturing the improved separation columns |
| JP2002301367A (ja) * | 2001-04-05 | 2002-10-15 | Gl Sciences Inc | クロマトグラフィー用多孔質体の製造方法 |
| CN101585507B (zh) * | 2009-06-23 | 2013-07-03 | 中国科学院上海微系统与信息技术研究所 | 一种pdms微流控芯片中通孔结构的制作方法 |
-
2010
- 2010-02-25 JP JP2010040077A patent/JP2011174856A/ja active Pending
- 2010-12-24 CN CN2010800647168A patent/CN102812354A/zh active Pending
- 2010-12-24 WO PCT/JP2010/073369 patent/WO2011104990A1/ja not_active Ceased
- 2010-12-24 EP EP10846653.3A patent/EP2541245A4/en not_active Withdrawn
- 2010-12-24 US US13/581,418 patent/US20120318049A1/en not_active Abandoned
-
2011
- 2011-02-23 TW TW100106052A patent/TWI421493B/zh not_active IP Right Cessation
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1720438A (zh) * | 2002-11-29 | 2006-01-11 | 日本电气株式会社 | 分离设备和分离方法 |
| TW200831173A (en) * | 2006-08-14 | 2008-08-01 | Tokyo Electron Ltd | Column for chromatography and its manufacturing method |
| US20090314065A1 (en) * | 2007-08-24 | 2009-12-24 | Tokyo Electron Limited | Chromatography detector |
| WO2009128294A1 (ja) * | 2008-04-19 | 2009-10-22 | ブラザー工業株式会社 | 検査対象受体及び当該検査対象受体を備えた検査装置 |
Also Published As
| Publication number | Publication date |
|---|---|
| JP2011174856A (ja) | 2011-09-08 |
| TW201142281A (en) | 2011-12-01 |
| US20120318049A1 (en) | 2012-12-20 |
| CN102812354A (zh) | 2012-12-05 |
| WO2011104990A1 (ja) | 2011-09-01 |
| EP2541245A4 (en) | 2013-12-18 |
| EP2541245A1 (en) | 2013-01-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM4A | Annulment or lapse of patent due to non-payment of fees |