JP2011174856A - クロマトグラフィー用カラム、その製造方法、および分析装置 - Google Patents

クロマトグラフィー用カラム、その製造方法、および分析装置 Download PDF

Info

Publication number
JP2011174856A
JP2011174856A JP2010040077A JP2010040077A JP2011174856A JP 2011174856 A JP2011174856 A JP 2011174856A JP 2010040077 A JP2010040077 A JP 2010040077A JP 2010040077 A JP2010040077 A JP 2010040077A JP 2011174856 A JP2011174856 A JP 2011174856A
Authority
JP
Japan
Prior art keywords
column
side wall
mobile phase
side walls
pillars
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2010040077A
Other languages
English (en)
Japanese (ja)
Other versions
JP2011174856A5 (enExample
Inventor
Seokhyoung Hong
錫亨 洪
Tomofumi Kiyomoto
智文 清元
Koshi Kobayashi
宏資 小林
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Tokyo Electron Ltd
Shinwa Chemical Industries Ltd
Original Assignee
Tokyo Electron Ltd
Shinwa Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tokyo Electron Ltd, Shinwa Chemical Industries Ltd filed Critical Tokyo Electron Ltd
Priority to JP2010040077A priority Critical patent/JP2011174856A/ja
Priority to PCT/JP2010/073369 priority patent/WO2011104990A1/ja
Priority to CN2010800647168A priority patent/CN102812354A/zh
Priority to EP10846653.3A priority patent/EP2541245A4/en
Priority to US13/581,418 priority patent/US20120318049A1/en
Priority to TW100106052A priority patent/TWI421493B/zh
Publication of JP2011174856A publication Critical patent/JP2011174856A/ja
Publication of JP2011174856A5 publication Critical patent/JP2011174856A5/ja
Pending legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography
    • G01N30/60Construction of the column
    • G01N30/6095Micromachined or nanomachined, e.g. micro- or nanosize
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502761Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip specially adapted for handling suspended solids or molecules independently from the bulk fluid flow, e.g. for trapping or sorting beads, for physically stretching molecules
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/04Moving fluids with specific forces or mechanical means
    • B01L2400/0475Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
    • B01L2400/0487Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/08Regulating or influencing the flow resistance
    • B01L2400/084Passive control of flow resistance
    • B01L2400/086Passive control of flow resistance using baffles or other fixed flow obstructions

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Clinical Laboratory Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hematology (AREA)
  • Fluid Mechanics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Nanotechnology (AREA)
  • Dispersion Chemistry (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
JP2010040077A 2010-02-25 2010-02-25 クロマトグラフィー用カラム、その製造方法、および分析装置 Pending JP2011174856A (ja)

Priority Applications (6)

Application Number Priority Date Filing Date Title
JP2010040077A JP2011174856A (ja) 2010-02-25 2010-02-25 クロマトグラフィー用カラム、その製造方法、および分析装置
PCT/JP2010/073369 WO2011104990A1 (ja) 2010-02-25 2010-12-24 クロマトグラフィー用カラム、その製造方法、および分析装置
CN2010800647168A CN102812354A (zh) 2010-02-25 2010-12-24 色谱分析柱及其制造方法、以及分析装置
EP10846653.3A EP2541245A4 (en) 2010-02-25 2010-12-24 CHROMATOGRAPHY COLUMN, PROCESS FOR OBTAINING COLUMN AND ANALYSIS DEVICE
US13/581,418 US20120318049A1 (en) 2010-02-25 2010-12-24 Column for chromatography, method for producing same, and analysis device
TW100106052A TWI421493B (zh) 2010-02-25 2011-02-23 色層分析用管柱及其製造方法與分析裝置

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2010040077A JP2011174856A (ja) 2010-02-25 2010-02-25 クロマトグラフィー用カラム、その製造方法、および分析装置

Publications (2)

Publication Number Publication Date
JP2011174856A true JP2011174856A (ja) 2011-09-08
JP2011174856A5 JP2011174856A5 (enExample) 2013-04-04

Family

ID=44506425

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2010040077A Pending JP2011174856A (ja) 2010-02-25 2010-02-25 クロマトグラフィー用カラム、その製造方法、および分析装置

Country Status (6)

Country Link
US (1) US20120318049A1 (enExample)
EP (1) EP2541245A4 (enExample)
JP (1) JP2011174856A (enExample)
CN (1) CN102812354A (enExample)
TW (1) TWI421493B (enExample)
WO (1) WO2011104990A1 (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2016508440A (ja) * 2013-02-05 2016-03-22 ファルマフライディクス・ナムローゼ・フェンノートシャップPharmafluidics Nv 化学反応器デバイス
KR20190025924A (ko) * 2016-07-04 2019-03-12 파마플루이딕스 엔브이 화학 반응기의 제조

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10073068B2 (en) 2013-09-18 2018-09-11 Agilent Technologies, Inc. Liquid chromatography columns with structured walls
CN108333283B (zh) * 2017-01-20 2024-07-19 中国科学院上海微系统与信息技术研究所 一种含有流线型椭圆微柱阵列的微色谱柱及其制备方法
BE1026910B1 (nl) * 2018-12-21 2020-07-22 Pharmafluidics N V Chemische reactoren
BE1028976B1 (nl) * 2020-12-30 2022-08-01 Pharmafluidics N V Pilaarstructuren

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH07120450A (ja) * 1993-10-22 1995-05-12 Sumika Bunseki Center:Kk 多孔質体クロマトグラフィー用カラム
JP2002301367A (ja) * 2001-04-05 2002-10-15 Gl Sciences Inc クロマトグラフィー用多孔質体の製造方法
WO2004051231A1 (ja) * 2002-11-29 2004-06-17 Nec Corporation 分離装置および分離方法
WO2008020593A1 (en) * 2006-08-14 2008-02-21 Tokyo Electron Limited Column for chromatography and method for producing the same
WO2009028238A1 (ja) * 2007-08-24 2009-03-05 Tokyo Electron Limited クロマト検出装置

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6156273A (en) * 1997-05-27 2000-12-05 Purdue Research Corporation Separation columns and methods for manufacturing the improved separation columns
JP5331798B2 (ja) * 2008-04-19 2013-10-30 ブラザー工業株式会社 検査対象受体及び当該検査対象受体を備えた検査装置
CN101585507B (zh) * 2009-06-23 2013-07-03 中国科学院上海微系统与信息技术研究所 一种pdms微流控芯片中通孔结构的制作方法

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH07120450A (ja) * 1993-10-22 1995-05-12 Sumika Bunseki Center:Kk 多孔質体クロマトグラフィー用カラム
JP2002301367A (ja) * 2001-04-05 2002-10-15 Gl Sciences Inc クロマトグラフィー用多孔質体の製造方法
WO2004051231A1 (ja) * 2002-11-29 2004-06-17 Nec Corporation 分離装置および分離方法
WO2008020593A1 (en) * 2006-08-14 2008-02-21 Tokyo Electron Limited Column for chromatography and method for producing the same
WO2009028238A1 (ja) * 2007-08-24 2009-03-05 Tokyo Electron Limited クロマト検出装置

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
JPN6014008569; M.De Pra,et.al.: 'Experimental Study on Band Dispersion in Channels Structured with Micropillars' Analytical Chemistry Vol.78, 2006, 6519-6525 *

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2016508440A (ja) * 2013-02-05 2016-03-22 ファルマフライディクス・ナムローゼ・フェンノートシャップPharmafluidics Nv 化学反応器デバイス
KR20190025924A (ko) * 2016-07-04 2019-03-12 파마플루이딕스 엔브이 화학 반응기의 제조
KR102380815B1 (ko) 2016-07-04 2022-03-30 파마플루이딕스 엔브이 화학 반응기의 제조
US11724259B2 (en) 2016-07-04 2023-08-15 Pharmafluidics Nv Production of chemical reactors

Also Published As

Publication number Publication date
TW201142281A (en) 2011-12-01
US20120318049A1 (en) 2012-12-20
TWI421493B (zh) 2014-01-01
CN102812354A (zh) 2012-12-05
WO2011104990A1 (ja) 2011-09-01
EP2541245A4 (en) 2013-12-18
EP2541245A1 (en) 2013-01-02

Similar Documents

Publication Publication Date Title
JP2011174856A (ja) クロマトグラフィー用カラム、その製造方法、および分析装置
WO2008020593A1 (en) Column for chromatography and method for producing the same
EP2953716B1 (en) Chemical reactor device
JP6509330B2 (ja) 微細構造分離フィルタ
Vangelooven et al. Design and evaluation of flow distributors for microfabricated pillar array columns
Slentz et al. Geometric effects of collocated monolithic support structures on separation performance in microfabricated systems
CN112816608B (zh) 微色谱柱及制备方法
KR101584083B1 (ko) 미소입자의 변형성 및 피로 특성 분석 장치
US12215023B2 (en) Microfluidic devices and associated methods
CN110052299A (zh) 一种用于微流控芯片预设层的阵列结构
CN206460008U (zh) 一种含有流线型椭圆微柱阵列的微色谱柱
CN115060842A (zh) 一种含有交错排列椭圆微柱阵列的微色谱柱及其制备方法
CN108333283A (zh) 一种含有流线型椭圆微柱阵列的微色谱柱及其制备方法
US12011701B2 (en) Chemical reactors
BE1027013B1 (nl) Filter voor chemische reactoren
US20240157361A1 (en) Microfluidic device
JP4661125B2 (ja) 成分分離素子およびその製造方法
Nawada The use of 3D-printing in the study of chromatographic packed bed microstructures.
RU2642572C1 (ru) Насыпная насадка для массообменных колонн

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20130215

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20130215

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20140304

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20140421

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20141104

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20150310