TWI402074B - 藉由特定多糖類來降低胃灼熱及胃食道逆流疾病(gerd)之症狀的方法 - Google Patents

藉由特定多糖類來降低胃灼熱及胃食道逆流疾病(gerd)之症狀的方法 Download PDF

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Publication number
TWI402074B
TWI402074B TW096117078A TW96117078A TWI402074B TW I402074 B TWI402074 B TW I402074B TW 096117078 A TW096117078 A TW 096117078A TW 96117078 A TW96117078 A TW 96117078A TW I402074 B TWI402074 B TW I402074B
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TW
Taiwan
Prior art keywords
polysaccharide
fenugreek
acid
viscosity
galactomannose
Prior art date
Application number
TW096117078A
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English (en)
Chinese (zh)
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TW200812596A (en
Inventor
Maria Anna Verbruggen
Calvin T Kelly
Blaine G Sudom
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Frutarom Netherlands B V
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Application filed by Frutarom Netherlands B V filed Critical Frutarom Netherlands B V
Publication of TW200812596A publication Critical patent/TW200812596A/zh
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Publication of TWI402074B publication Critical patent/TWI402074B/zh

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0065Forms with gastric retention, e.g. floating on gastric juice, adhering to gastric mucosa, expanding to prevent passage through the pylorus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/716Glucans
    • A61K31/718Starch or degraded starch, e.g. amylose, amylopectin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/716Glucans
    • A61K31/722Chitin, chitosan
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/716Glucans
    • A61K31/724Cyclodextrins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/731Carrageenans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/732Pectin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/736Glucomannans or galactomannans, e.g. locust bean gum, guar gum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/738Cross-linked polysaccharides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0087Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/06Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Medicines Containing Plant Substances (AREA)
TW096117078A 2006-05-16 2007-05-14 藉由特定多糖類來降低胃灼熱及胃食道逆流疾病(gerd)之症狀的方法 TWI402074B (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP06076056A EP1859786A1 (en) 2006-05-16 2006-05-16 A method to reduce the symptoms of heartburn and gastro-oesophageal reflux disease (GERD) by specific polysaccharides
US80631306P 2006-06-30 2006-06-30

Publications (2)

Publication Number Publication Date
TW200812596A TW200812596A (en) 2008-03-16
TWI402074B true TWI402074B (zh) 2013-07-21

Family

ID=37806824

Family Applications (1)

Application Number Title Priority Date Filing Date
TW096117078A TWI402074B (zh) 2006-05-16 2007-05-14 藉由特定多糖類來降低胃灼熱及胃食道逆流疾病(gerd)之症狀的方法

Country Status (9)

Country Link
US (2) US20090252792A1 (https=)
EP (2) EP1859786A1 (https=)
JP (1) JP2009537512A (https=)
KR (1) KR20090048393A (https=)
AT (1) ATE514415T1 (https=)
AU (1) AU2007250624B2 (https=)
RU (1) RU2432167C2 (https=)
TW (1) TWI402074B (https=)
WO (1) WO2007133082A1 (https=)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090148530A1 (en) * 2007-12-08 2009-06-11 Jamie Koufman Method for prevention and treatment of reflux injury in the aerodigestive tract and laryngopharynx caused by pepsin
EP2346351B1 (en) 2008-09-22 2019-07-03 Rubicon Research Private Limited Compositions exhibiting delayed transit through the gastrointestinal tract
DK2564840T3 (en) 2010-04-26 2015-03-02 De Santos Angel Manuel Gago Compositions for symptomatic relief of abdominal pain or gastroesophageal reflux
ITRM20120041A1 (it) * 2012-02-08 2013-08-09 Dicofarm Spa "prodotto a base di glucomannano e chitosano utile per il trattamento del reflusso gastroesofageo"
ITRM20120084A1 (it) * 2012-03-07 2013-09-08 Aboca Spa Societa Agricola Miscela prebiotica.
EP2827839B1 (en) 2012-03-20 2019-02-27 Particle Dynamics International, LLC Gelling agent-based dosage form
ITMI20130960A1 (it) * 2013-06-11 2014-12-12 Novintethical Pharma Sagl Composizioni a base di xiloglucano per il trattamento di disturbi gastrointestinali
IT201700091733A1 (it) * 2017-08-08 2019-02-08 Neilos S R L Composizione per somministrazione orale per uso nel trattamento terapeutico o preventivo dei disturbi o malattia da reflusso gastroesofageo
JP2019064980A (ja) * 2017-10-03 2019-04-25 小林製薬株式会社 逆流性食道炎改善剤
AU2019312160B2 (en) 2018-07-23 2024-02-22 Nutragenom, Llc Composition and methods for generating and sustaining molecular hydrogen (H2) in aqueous systems
CN111227156A (zh) * 2020-01-20 2020-06-05 陕西科技大学 一种抑制反酸的固体饮料及其制备方法
WO2022240224A1 (ko) * 2021-05-14 2022-11-17 한국식품연구원 젤란검을 유효성분으로 하는 장내 균총 개선용 조성물 및 이를 포함하는 대사성 질환 개선, 예방 또는 치료용 조성물
TWI777673B (zh) * 2021-07-16 2022-09-11 陳昭誠 由β-1-4-葡聚醣形成之纖維於製備用於治療或預防胃食道逆流之組成物之用途

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2349570A (en) * 1999-05-05 2000-11-08 Reckitt & Colmann Prod Ltd Compositions for treatment of disorders of the oesophagus

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3152319C2 (de) * 1980-09-03 1986-05-07 Kyosei Pharmaceutical Co., Ltd., Hokkaido Verwendung einer Lösung eines Salzes der Alginsäure zur Behandlung von Strahlenschäden und Ulcera
IL108583A (en) * 1994-02-07 1997-06-10 Yissum Res Dev Co Galactomannan emulsions and comestible products containing the same
GB9708773D0 (en) * 1997-04-30 1997-06-25 Reckitt & Colmann Prod Ltd Organic compositions
CA2206157C (en) * 1997-05-26 2000-06-13 Cheng, Peter Method of extraction of commercially valuable fractions of fenugreek
GB0005743D0 (en) * 2000-03-10 2000-05-03 Reckitt & Colmann Prod Ltd Pharmaceutical compositions including alginates
GB2384986B (en) * 2002-02-12 2004-01-07 Reckitt Benckiser Healthcare Compositions for the treatment of disorders of the upper gastrointestinal tract
CN1780880B (zh) * 2003-04-25 2010-04-28 雷克特本克斯尔保健(英国)有限公司 可增稠的组合物
ATE390142T1 (de) * 2003-05-14 2008-04-15 Indus Biotech Pvt Ltd Synergistische zusammensetzung zur behandlung von diabetes mellitus

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2349570A (en) * 1999-05-05 2000-11-08 Reckitt & Colmann Prod Ltd Compositions for treatment of disorders of the oesophagus

Also Published As

Publication number Publication date
RU2008149527A (ru) 2010-06-27
KR20090048393A (ko) 2009-05-13
US20090252792A1 (en) 2009-10-08
EP2026763A1 (en) 2009-02-25
JP2009537512A (ja) 2009-10-29
AU2007250624B2 (en) 2012-09-20
WO2007133082A1 (en) 2007-11-22
US20120231078A1 (en) 2012-09-13
TW200812596A (en) 2008-03-16
RU2432167C2 (ru) 2011-10-27
EP1859786A1 (en) 2007-11-28
AU2007250624A1 (en) 2007-11-22
ATE514415T1 (de) 2011-07-15
EP2026763B1 (en) 2011-06-29

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