RU2432167C2 - Способ уменьшения симптомов изжоги и гастроэзофагиальной рефлюксной болезни (гэрб) с помощью особых полисахаридов - Google Patents

Способ уменьшения симптомов изжоги и гастроэзофагиальной рефлюксной болезни (гэрб) с помощью особых полисахаридов Download PDF

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RU2432167C2
RU2432167C2 RU2008149527/15A RU2008149527A RU2432167C2 RU 2432167 C2 RU2432167 C2 RU 2432167C2 RU 2008149527/15 A RU2008149527/15 A RU 2008149527/15A RU 2008149527 A RU2008149527 A RU 2008149527A RU 2432167 C2 RU2432167 C2 RU 2432167C2
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RU
Russia
Prior art keywords
polysaccharide
reflux disease
heartburn
acid
viscosity
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RU2008149527/15A
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English (en)
Russian (ru)
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RU2008149527A (ru
Inventor
Мария Анна ВЕРБРЮГГЕН (NL)
Мария Анна ВЕРБРЮГГЕН
Келвин Т. КЕЛЛИ (CA)
Келвин Т. КЕЛЛИ
Блэйн Г. СЬЮДОМ (CA)
Блэйн Г. СЬЮДОМ
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Фрютаром Незерландс Б. В.
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0065—Forms with gastric retention, e.g. floating on gastric juice, adhering to gastric mucosa, expanding to prevent passage through the pylorus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/716—Glucans
    • A61K31/718—Starch or degraded starch, e.g. amylose, amylopectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/716—Glucans
    • A61K31/722—Chitin, chitosan
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/716—Glucans
    • A61K31/724—Cyclodextrins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/731—Carrageenans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/732—Pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/736—Glucomannans or galactomannans, e.g. locust bean gum, guar gum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/738—Cross-linked polysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Medicines Containing Plant Substances (AREA)
RU2008149527/15A 2006-05-16 2007-05-16 Способ уменьшения симптомов изжоги и гастроэзофагиальной рефлюксной болезни (гэрб) с помощью особых полисахаридов RU2432167C2 (ru)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
EP06076056.8 2006-05-16
EP06076056A EP1859786A1 (en) 2006-05-16 2006-05-16 A method to reduce the symptoms of heartburn and gastro-oesophageal reflux disease (GERD) by specific polysaccharides
US80631306P 2006-06-30 2006-06-30
US60/806,313 2006-06-30

Publications (2)

Publication Number Publication Date
RU2008149527A RU2008149527A (ru) 2010-06-27
RU2432167C2 true RU2432167C2 (ru) 2011-10-27

Family

ID=37806824

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2008149527/15A RU2432167C2 (ru) 2006-05-16 2007-05-16 Способ уменьшения симптомов изжоги и гастроэзофагиальной рефлюксной болезни (гэрб) с помощью особых полисахаридов

Country Status (9)

Country Link
US (2) US20090252792A1 (https=)
EP (2) EP1859786A1 (https=)
JP (1) JP2009537512A (https=)
KR (1) KR20090048393A (https=)
AT (1) ATE514415T1 (https=)
AU (1) AU2007250624B2 (https=)
RU (1) RU2432167C2 (https=)
TW (1) TWI402074B (https=)
WO (1) WO2007133082A1 (https=)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090148530A1 (en) * 2007-12-08 2009-06-11 Jamie Koufman Method for prevention and treatment of reflux injury in the aerodigestive tract and laryngopharynx caused by pepsin
EP2346351B1 (en) 2008-09-22 2019-07-03 Rubicon Research Private Limited Compositions exhibiting delayed transit through the gastrointestinal tract
DK2564840T3 (en) 2010-04-26 2015-03-02 De Santos Angel Manuel Gago Compositions for symptomatic relief of abdominal pain or gastroesophageal reflux
ITRM20120041A1 (it) * 2012-02-08 2013-08-09 Dicofarm Spa "prodotto a base di glucomannano e chitosano utile per il trattamento del reflusso gastroesofageo"
ITRM20120084A1 (it) * 2012-03-07 2013-09-08 Aboca Spa Societa Agricola Miscela prebiotica.
EP2827839B1 (en) 2012-03-20 2019-02-27 Particle Dynamics International, LLC Gelling agent-based dosage form
ITMI20130960A1 (it) * 2013-06-11 2014-12-12 Novintethical Pharma Sagl Composizioni a base di xiloglucano per il trattamento di disturbi gastrointestinali
IT201700091733A1 (it) * 2017-08-08 2019-02-08 Neilos S R L Composizione per somministrazione orale per uso nel trattamento terapeutico o preventivo dei disturbi o malattia da reflusso gastroesofageo
JP2019064980A (ja) * 2017-10-03 2019-04-25 小林製薬株式会社 逆流性食道炎改善剤
AU2019312160B2 (en) 2018-07-23 2024-02-22 Nutragenom, Llc Composition and methods for generating and sustaining molecular hydrogen (H2) in aqueous systems
CN111227156A (zh) * 2020-01-20 2020-06-05 陕西科技大学 一种抑制反酸的固体饮料及其制备方法
WO2022240224A1 (ko) * 2021-05-14 2022-11-17 한국식품연구원 젤란검을 유효성분으로 하는 장내 균총 개선용 조성물 및 이를 포함하는 대사성 질환 개선, 예방 또는 치료용 조성물
TWI777673B (zh) * 2021-07-16 2022-09-11 陳昭誠 由β-1-4-葡聚醣形成之纖維於製備用於治療或預防胃食道逆流之組成物之用途

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2349570A (en) * 1999-05-05 2000-11-08 Reckitt & Colmann Prod Ltd Compositions for treatment of disorders of the oesophagus
WO2001066119A2 (en) * 2000-03-10 2001-09-13 Reckitt Benckiser Healthcare (Uk) Limited Pharmaceutical compositions including alginates

Family Cites Families (7)

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DE3152319C2 (de) * 1980-09-03 1986-05-07 Kyosei Pharmaceutical Co., Ltd., Hokkaido Verwendung einer Lösung eines Salzes der Alginsäure zur Behandlung von Strahlenschäden und Ulcera
IL108583A (en) * 1994-02-07 1997-06-10 Yissum Res Dev Co Galactomannan emulsions and comestible products containing the same
GB9708773D0 (en) * 1997-04-30 1997-06-25 Reckitt & Colmann Prod Ltd Organic compositions
CA2206157C (en) * 1997-05-26 2000-06-13 Cheng, Peter Method of extraction of commercially valuable fractions of fenugreek
GB2384986B (en) * 2002-02-12 2004-01-07 Reckitt Benckiser Healthcare Compositions for the treatment of disorders of the upper gastrointestinal tract
CN1780880B (zh) * 2003-04-25 2010-04-28 雷克特本克斯尔保健(英国)有限公司 可增稠的组合物
ATE390142T1 (de) * 2003-05-14 2008-04-15 Indus Biotech Pvt Ltd Synergistische zusammensetzung zur behandlung von diabetes mellitus

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2349570A (en) * 1999-05-05 2000-11-08 Reckitt & Colmann Prod Ltd Compositions for treatment of disorders of the oesophagus
WO2001066119A2 (en) * 2000-03-10 2001-09-13 Reckitt Benckiser Healthcare (Uk) Limited Pharmaceutical compositions including alginates

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Н.К.Batchelor et al. An in vitro mucosal model for prediction of the bioadhesion of alginate solutions to the oesophagus // International Journal of Pharmaceutics 238 (2002), 123-132. *

Also Published As

Publication number Publication date
RU2008149527A (ru) 2010-06-27
KR20090048393A (ko) 2009-05-13
US20090252792A1 (en) 2009-10-08
EP2026763A1 (en) 2009-02-25
TWI402074B (zh) 2013-07-21
JP2009537512A (ja) 2009-10-29
AU2007250624B2 (en) 2012-09-20
WO2007133082A1 (en) 2007-11-22
US20120231078A1 (en) 2012-09-13
TW200812596A (en) 2008-03-16
EP1859786A1 (en) 2007-11-28
AU2007250624A1 (en) 2007-11-22
ATE514415T1 (de) 2011-07-15
EP2026763B1 (en) 2011-06-29

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