TWI398436B - 具苯基之苯基-〔１，２，４〕-二唑-５-酮衍生物，其製備方法及其作為醫藥品之用途 - Google Patents

具苯基之苯基-〔１，２，４〕-二唑-５-酮衍生物，其製備方法及其作為醫藥品之用途 Download PDF

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TWI398436B
TWI398436B TW095135660A TW95135660A TWI398436B TW I398436 B TWI398436 B TW I398436B TW 095135660 A TW095135660 A TW 095135660A TW 95135660 A TW95135660 A TW 95135660A TW I398436 B TWI398436 B TW I398436B
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phenyl
methyl
thiazol
diazol
alkyl
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TW095135660A
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English (en)
Chinese (zh)
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TW200728293A (en
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Stefanie Keil
Patrick Bernardelli
Matthias Urmann
Hans Matter
Wolfgang Wendler
Maike Glien
Karen Chandross
Lan Lee
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Sanofi Aventis
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    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
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    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4245—Oxadiazoles
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    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
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    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

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TW095135660A 2005-09-29 2006-09-27 具苯基之苯基-〔１，２，４〕-二唑-５-酮衍生物，其製備方法及其作為醫藥品之用途 TWI398436B (zh)

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Application Number Priority Date Filing Date Title
EP05021235 2005-09-29

Publications (2)

Publication Number Publication Date
TW200728293A TW200728293A (en) 2007-08-01
TWI398436B true TWI398436B (zh) 2013-06-11

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ID=35809809

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TW095135660A TWI398436B (zh) 2005-09-29 2006-09-27 具苯基之苯基-〔１，２，４〕-二唑-５-酮衍生物，其製備方法及其作為醫藥品之用途
TW095135657A TW200811154A (en) 2005-09-29 2006-09-27 Phenyl-1,2,4-oxadiazolone derivatives with phenyl group, processes for their preparation and their use as pharmaceuticals

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TW095135657A TW200811154A (en) 2005-09-29 2006-09-27 Phenyl-1,2,4-oxadiazolone derivatives with phenyl group, processes for their preparation and their use as pharmaceuticals

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US (3) US20080287409A1 (enExample)
EP (2) EP1931660B1 (enExample)
JP (2) JP5183479B2 (enExample)
KR (2) KR20080048520A (enExample)
CN (2) CN101273036A (enExample)
AR (2) AR056203A1 (enExample)
AT (1) ATE537167T1 (enExample)
AU (2) AU2006299092A1 (enExample)
BR (2) BRPI0616465A2 (enExample)
CA (2) CA2624105C (enExample)
CR (1) CR9784A (enExample)
CY (1) CY1113376T1 (enExample)
DK (1) DK1931660T3 (enExample)
DO (2) DOP2006000205A (enExample)
EC (1) ECSP088323A (enExample)
ES (1) ES2392181T3 (enExample)
IL (2) IL190228A0 (enExample)
MA (2) MA29804B1 (enExample)
MY (2) MY149182A (enExample)
NO (2) NO20081370L (enExample)
NZ (2) NZ566875A (enExample)
PE (2) PE20070545A1 (enExample)
PL (1) PL1931660T3 (enExample)
PT (1) PT1931660E (enExample)
RU (2) RU2008112201A (enExample)
SI (1) SI1931660T1 (enExample)
TN (1) TNSN08145A1 (enExample)
TW (2) TWI398436B (enExample)
UY (2) UY29830A1 (enExample)
WO (2) WO2007039172A1 (enExample)
ZA (1) ZA200801630B (enExample)

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US10954231B2 (en) 2006-10-16 2021-03-23 Bionomics Limited Anxiolytic compounds
DK2074123T3 (da) 2006-10-16 2013-01-14 Bionomics Ltd Nye anxiolytiske forbindelser
EP2025674A1 (de) 2007-08-15 2009-02-18 sanofi-aventis Substituierte Tetrahydronaphthaline, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
DE102007063671A1 (de) 2007-11-13 2009-06-25 Sanofi-Aventis Deutschland Gmbh Neue kristalline Diphenylazetidinonhydrate, diese Verbindungen enthaltende Arzneimittel und deren Verwendung
US20210130285A1 (en) * 2008-03-19 2021-05-06 Aurimmed Pharma, Inc. Novel compounds advantageous in the treatment of central nervous system diseases and disorders
US10793515B2 (en) * 2008-03-19 2020-10-06 Aurimmed Pharma, Inc. Compounds advantageous in the treatment of central nervous system diseases and disorders
AR072707A1 (es) 2008-07-09 2010-09-15 Sanofi Aventis Compuestos heterociclicos, procesos para su preparacion, medicamentos que comprenden estos compuestos y el uso de los mismos
WO2010068601A1 (en) 2008-12-08 2010-06-17 Sanofi-Aventis A crystalline heteroaromatic fluoroglycoside hydrate, processes for making, methods of use and pharmaceutical compositions thereof
PT2470552E (pt) 2009-08-26 2014-01-30 Sanofi Sa Novos hidratos de fluoroglicósido heteroaromáticos cristalinos, fármacos compreendendo estes compostos e sua utilização
WO2011107494A1 (de) 2010-03-03 2011-09-09 Sanofi Neue aromatische glykosidderivate, diese verbindungen enthaltende arzneimittel und deren verwendung
EP2566858A2 (en) 2010-05-04 2013-03-13 Pfizer Inc. Heterocyclic derivatives as alk inhibitors
EP2582709B1 (de) 2010-06-18 2018-01-24 Sanofi Azolopyridin-3-on-derivate als inhibitoren von lipasen und phospholipasen
US8530413B2 (en) 2010-06-21 2013-09-10 Sanofi Heterocyclically substituted methoxyphenyl derivatives with an oxo group, processes for preparation thereof and use thereof as medicaments
TW201215388A (en) 2010-07-05 2012-04-16 Sanofi Sa (2-aryloxyacetylamino)phenylpropionic acid derivatives, processes for preparation thereof and use thereof as medicaments
TW201221505A (en) 2010-07-05 2012-06-01 Sanofi Sa Aryloxyalkylene-substituted hydroxyphenylhexynoic acids, process for preparation thereof and use thereof as a medicament
TW201215387A (en) 2010-07-05 2012-04-16 Sanofi Aventis Spirocyclically substituted 1,3-propane dioxide derivatives, processes for preparation thereof and use thereof as a medicament
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WO2012120055A1 (de) 2011-03-08 2012-09-13 Sanofi Di- und trisubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung
EP2683700B1 (de) 2011-03-08 2015-02-18 Sanofi Tetrasubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung
EP2683705B1 (de) 2011-03-08 2015-04-22 Sanofi Di- und trisubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung
US8901114B2 (en) 2011-03-08 2014-12-02 Sanofi Oxathiazine derivatives substituted with carbocycles or heterocycles, method for producing same, drugs containing said compounds, and use thereof
EP2683704B1 (de) 2011-03-08 2014-12-17 Sanofi Verzweigte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung
CA2835450C (en) 2011-05-12 2020-05-12 Bionomics Limited Methods for preparing naphthyridines
WO2013037390A1 (en) 2011-09-12 2013-03-21 Sanofi 6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors
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