TWI262915B - Pyridazinone and triazinone compounds and use thereof as pharmaceutical preparations - Google Patents
Pyridazinone and triazinone compounds and use thereof as pharmaceutical preparationsInfo
- Publication number
- TWI262915B TWI262915B TW090123425A TW90123425A TWI262915B TW I262915 B TWI262915 B TW I262915B TW 090123425 A TW090123425 A TW 090123425A TW 90123425 A TW90123425 A TW 90123425A TW I262915 B TWI262915 B TW I262915B
- Authority
- TW
- Taiwan
- Prior art keywords
- group
- optionally substituted
- independent
- atom
- membered
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
- C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D237/24—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
- C07D237/04—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having less than three double bonds between ring members or between ring members and non-ring members
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
- C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D237/14—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Psychiatry (AREA)
- Urology & Nephrology (AREA)
- Pain & Pain Management (AREA)
- Oncology (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Psychology (AREA)
- Ophthalmology & Optometry (AREA)
- Hospice & Palliative Care (AREA)
- Immunology (AREA)
- Virology (AREA)
- Communicable Diseases (AREA)
- Tropical Medicine & Parasitology (AREA)
- Addiction (AREA)
- Molecular Biology (AREA)
- Heart & Thoracic Surgery (AREA)
- AIDS & HIV (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Otolaryngology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2000282636 | 2000-09-18 | ||
JP2000289412 | 2000-09-22 | ||
JP2000342614 | 2000-11-09 | ||
GB0102822A GB0102822D0 (en) | 2001-02-05 | 2001-02-05 | Pyridazinone compounds manufacturing methods thereof and pharmaceuticals thereof |
GB0102824A GB0102824D0 (en) | 2001-02-05 | 2001-02-05 | Triazinone compounds process for producing the same and pharmaceuticals thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
TWI262915B true TWI262915B (en) | 2006-10-01 |
Family
ID=27516005
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
TW090123425A TWI262915B (en) | 2000-09-18 | 2001-09-19 | Pyridazinone and triazinone compounds and use thereof as pharmaceutical preparations |
Country Status (16)
Country | Link |
---|---|
US (2) | US20030225081A1 (zh) |
EP (1) | EP1319659B1 (zh) |
JP (2) | JP4233868B2 (zh) |
KR (1) | KR100770327B1 (zh) |
CN (1) | CN100473647C (zh) |
AT (1) | ATE425148T1 (zh) |
AU (2) | AU2001290229B2 (zh) |
CA (2) | CA2422589C (zh) |
DE (1) | DE60137948D1 (zh) |
HU (1) | HU228961B1 (zh) |
IL (2) | IL154709A0 (zh) |
MX (1) | MXPA03002324A (zh) |
NO (1) | NO327813B1 (zh) |
NZ (1) | NZ524745A (zh) |
TW (1) | TWI262915B (zh) |
WO (1) | WO2002022587A1 (zh) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TWI644916B (zh) * | 2015-11-13 | 2018-12-21 | 日商衛材R&D企管股份有限公司 | 哌喃并二吡啶化合物 |
Families Citing this family (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
MXPA04002939A (es) * | 2001-09-26 | 2004-06-18 | Kowa Co | Derivados hidrosolubles de finilpiridacina y farmacos que los contienen. |
US6861428B2 (en) * | 2001-09-26 | 2005-03-01 | Kowa Co., Ltd. | Water-soluble phenylpyridazine compounds and compositions containing the same |
FR2847253B1 (fr) * | 2002-11-19 | 2007-05-18 | Aventis Pharma Sa | Nouveaux derives de pyridazinones a titre de medicaments et compositions pharmaceutiques les renfermant |
US7462613B2 (en) | 2002-11-19 | 2008-12-09 | Sanofi-Aventis Deutschland Gmbh | Pyridazinone derivatives as pharmaceuticals and pharmaceutical compositions containing them |
US7309701B2 (en) | 2002-11-19 | 2007-12-18 | Sanofi-Aventis Deutschland Gmbh | Pyridazinone derivatives as pharmaceuticals and pharmaceutical compositions containing them |
ATE511843T1 (de) * | 2005-04-04 | 2011-06-15 | Eisai R&D Man Co Ltd | Dihydropyridin-verbindungen für neurodegenerative erkrankungen und demenz |
DK1928454T3 (da) | 2005-05-10 | 2014-11-03 | Intermune Inc | Pyridonderivater til modulering af stress-aktiveret proteinkinasesystem |
WO2007058392A1 (ja) * | 2005-11-21 | 2007-05-24 | Japan Tobacco Inc. | ヘテロ環化合物およびその医薬用途 |
US8258136B2 (en) * | 2005-12-07 | 2012-09-04 | Sumitomo Chemical Company, Limited | Pyridazine compound and use thereof |
EA200970720A1 (ru) * | 2007-01-29 | 2009-12-30 | Кова Ко., Лтд. | Средство для лечения рассеянного склероза |
WO2008111590A2 (en) * | 2007-03-05 | 2008-09-18 | Eisai R & D Management Co., Ltd. | Ampa and nmda receptor antagonists for neurodegenerative diseases |
EP2148673A1 (en) * | 2007-04-26 | 2010-02-03 | Eisai R&D Management Co., Ltd. | Cinnamide compounds for dementia |
EP2296653B1 (en) | 2008-06-03 | 2016-01-27 | Intermune, Inc. | Compounds and methods for treating inflammatory and fibrotic disorders |
UA103918C2 (en) | 2009-03-02 | 2013-12-10 | Айерем Элелси | N-(hetero)aryl, 2-(hetero)aryl-substituted acetamides for use as wnt signaling modulators |
AR092742A1 (es) | 2012-10-02 | 2015-04-29 | Intermune Inc | Piridinonas antifibroticas |
EP2951157A1 (en) | 2013-02-04 | 2015-12-09 | Merck Patent GmbH | Positive allosteric modulators of mglur3 |
US8877766B2 (en) * | 2013-02-15 | 2014-11-04 | Peter F. Kador | Neuroprotective multifunctional antioxidants and their monofunctional analogs |
RU2692485C2 (ru) | 2014-04-02 | 2019-06-25 | Интермьюн, Инк. | Противофиброзные пиридиноны |
WO2016051799A1 (ja) * | 2014-10-01 | 2016-04-07 | 学校法人同志社 | 2-アミノヒドロキノン誘導体及びタウ凝集阻害剤 |
CN111153859B (zh) * | 2015-04-15 | 2021-09-03 | 江苏恩华药业股份有限公司 | 哒嗪酮类衍生物及其应用 |
WO2017202816A1 (en) | 2016-05-25 | 2017-11-30 | Bayer Pharma Aktiengesellschaft | 3-oxo-2,6-diphenyl-2,3-dihydropyridazine-4-carboxamides |
JOP20190193A1 (ar) | 2017-02-09 | 2019-08-08 | Bayer Pharma AG | ممركبات 2-أريل غير متجانس-3-أكسو-2، 3-ثنائي هيدرو بيريدازين-4-كربوكساميد لمعالجة السرطان |
SG11201909483WA (en) * | 2017-05-09 | 2019-11-28 | Eisai R&D Man Co Ltd | Crystals of pyranodipyridine compound |
WO2019101642A1 (en) | 2017-11-21 | 2019-05-31 | Bayer Aktiengesellschaft | Sulphur substituted 3-oxo-2,3-dihydropyridazine-4-carboxamides |
US11591311B2 (en) | 2017-11-21 | 2023-02-28 | Bayer Aktiengesellschaft | 3-oxo-6-heteroaryl-2-phenyl-2,3-dihydropyridazine-4-carboxamides |
US20220347175A1 (en) * | 2018-07-19 | 2022-11-03 | Sumitomo Dainippon Pharma Co., Ltd. | Pyridazinone derivative |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3014034A (en) * | 1959-01-22 | 1961-12-19 | Ciba Pharm Prod Inc | 1, 3-diaryl, 5-amino-pyridazinones |
US3018034A (en) * | 1959-11-17 | 1962-01-23 | Gen Applied Science Lab Inc | Propulsion device for vertical takeoff aircraft |
IL29949A (en) * | 1967-05-19 | 1971-08-25 | Seperic | Diphenyl-pyridazones and process for preparing same |
DE4134467A1 (de) * | 1991-10-18 | 1993-04-22 | Thomae Gmbh Dr K | Heterobiarylderivate, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung |
EP0478195B1 (en) * | 1990-09-21 | 1999-05-26 | Rohm And Haas Company | Dihydropyridazinones and pyridazinones as fungicides |
GB9206266D0 (en) * | 1992-03-23 | 1992-05-06 | Merck Sharp & Dohme | Therapeutic agents |
US5356902A (en) * | 1992-11-06 | 1994-10-18 | Eli Lilly And Company | Decahydroisoquinoline compounds as excitatory amino acid receptor antagonists |
IL115889A0 (en) * | 1994-11-14 | 1996-01-31 | Rohm & Haas | Pyridazinones and their use as fungicides |
DE19643037A1 (de) * | 1996-10-18 | 1998-04-23 | Boehringer Ingelheim Kg | Neue Oxadiazole, Verfahren zu ihrer Herstellung sowie deren Verwendung als Arzneimittel |
IL123340A0 (en) * | 1997-02-20 | 1998-09-24 | Sumitomo Chemical Co | Pyridazin-3-one derivatives and their use |
TWI241295B (en) * | 1998-03-02 | 2005-10-11 | Kowa Co | Pyridazine derivative and medicine containing the same as effect component |
JP2000119257A (ja) * | 1998-08-14 | 2000-04-25 | Nippon Nohyaku Co Ltd | ピリダジノン誘導体 |
AU756275B2 (en) * | 1998-08-14 | 2003-01-09 | Nihon Nohyaku Co., Ltd. | Pyridazinone derivatives |
JP2000247959A (ja) * | 1999-02-26 | 2000-09-12 | Kowa Co | ピリダジン−3−オン誘導体及びこれを含有する医薬 |
KR100344790B1 (ko) * | 1999-10-07 | 2002-07-19 | 엘지전자주식회사 | 마이크로 기계구조를 이용한 주파수 가변 초고주파 필터 |
-
2001
- 2001-09-17 AT AT01970120T patent/ATE425148T1/de not_active IP Right Cessation
- 2001-09-17 NZ NZ524745A patent/NZ524745A/en not_active IP Right Cessation
- 2001-09-17 AU AU2001290229A patent/AU2001290229B2/en not_active Ceased
- 2001-09-17 WO PCT/JP2001/008058 patent/WO2002022587A1/ja active Application Filing
- 2001-09-17 DE DE60137948T patent/DE60137948D1/de not_active Expired - Lifetime
- 2001-09-17 CN CNB018158803A patent/CN100473647C/zh not_active Expired - Fee Related
- 2001-09-17 AU AU9022901A patent/AU9022901A/xx active Pending
- 2001-09-17 CA CA2422589A patent/CA2422589C/en not_active Expired - Fee Related
- 2001-09-17 MX MXPA03002324A patent/MXPA03002324A/es active IP Right Grant
- 2001-09-17 HU HU0302508A patent/HU228961B1/hu not_active IP Right Cessation
- 2001-09-17 EP EP01970120A patent/EP1319659B1/en not_active Expired - Lifetime
- 2001-09-17 KR KR1020037003807A patent/KR100770327B1/ko not_active IP Right Cessation
- 2001-09-17 CA CA2742411A patent/CA2742411A1/en not_active Abandoned
- 2001-09-17 IL IL15470901A patent/IL154709A0/xx active IP Right Grant
- 2001-09-17 JP JP2002526840A patent/JP4233868B2/ja not_active Expired - Fee Related
- 2001-09-17 US US10/380,783 patent/US20030225081A1/en not_active Abandoned
- 2001-09-19 TW TW090123425A patent/TWI262915B/zh not_active IP Right Cessation
-
2003
- 2003-03-03 IL IL154709A patent/IL154709A/en not_active IP Right Cessation
- 2003-03-17 NO NO20031232A patent/NO327813B1/no not_active IP Right Cessation
-
2006
- 2006-04-21 US US11/408,078 patent/US20060189622A1/en not_active Abandoned
-
2008
- 2008-06-13 JP JP2008154986A patent/JP4906790B2/ja not_active Expired - Fee Related
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TWI644916B (zh) * | 2015-11-13 | 2018-12-21 | 日商衛材R&D企管股份有限公司 | 哌喃并二吡啶化合物 |
Also Published As
Publication number | Publication date |
---|---|
WO2002022587A1 (fr) | 2002-03-21 |
US20030225081A1 (en) | 2003-12-04 |
NO327813B1 (no) | 2009-09-28 |
AU2001290229B2 (en) | 2006-12-07 |
NO20031232L (no) | 2003-05-19 |
HUP0302508A3 (en) | 2007-03-28 |
IL154709A (en) | 2007-09-20 |
JP2009007356A (ja) | 2009-01-15 |
NZ524745A (en) | 2006-01-27 |
US20060189622A1 (en) | 2006-08-24 |
IL154709A0 (en) | 2003-10-31 |
ATE425148T1 (de) | 2009-03-15 |
KR100770327B1 (ko) | 2007-10-25 |
CA2422589A1 (en) | 2003-03-17 |
KR20030030007A (ko) | 2003-04-16 |
JPWO2002022587A1 (ja) | 2004-01-22 |
DE60137948D1 (de) | 2009-04-23 |
AU9022901A (en) | 2002-03-26 |
CA2422589C (en) | 2011-08-09 |
CN1458924A (zh) | 2003-11-26 |
HUP0302508A2 (hu) | 2003-12-29 |
CN100473647C (zh) | 2009-04-01 |
HU228961B1 (en) | 2013-07-29 |
EP1319659A1 (en) | 2003-06-18 |
JP4233868B2 (ja) | 2009-03-04 |
CA2742411A1 (en) | 2002-03-21 |
MXPA03002324A (es) | 2003-06-06 |
JP4906790B2 (ja) | 2012-03-28 |
NO20031232D0 (no) | 2003-03-17 |
EP1319659A4 (en) | 2005-08-10 |
EP1319659B1 (en) | 2009-03-11 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
TWI262915B (en) | Pyridazinone and triazinone compounds and use thereof as pharmaceutical preparations | |
WO2005097129A3 (en) | 6-azaindole compound | |
MXPA03001136A (es) | Compuesto de 2-aminopiridina y uso medico del mismo. | |
WO2008108380A3 (en) | Pyrrole compounds | |
BR122017028096B8 (pt) | composto, composição farmacêutica, e, uso do composto | |
NO20070557L (no) | Ftalazinderivater som PARP-inhibitorer | |
TW200642683A (en) | Heterocyclic compound | |
MY141255A (en) | Phosphodiesterase 4 inhibitors, including n-substituted diarylamine analogs | |
ATE402164T1 (de) | Stickstoffhaltige verbindung mit kondensiertem ring und pyrazolylgruppe als substituent und medizinische zusammensetzung davon | |
WO2003042204A1 (fr) | Derive d'amine | |
CA2376835A1 (en) | Condensed imidazole compounds and a therapeutic agent for diabetes mellitus | |
MY145408A (en) | Dihydropyrazolopyrimidinone derivatives | |
NO20076145L (no) | Ureadeviater, fremgangsmater for deres fremstilling og anvendelse derav | |
NO20081892L (no) | Polycykliske karbamoylpyridonderivat med HIV-integraseinhiberende aktivitet | |
WO2003035640A1 (fr) | Composes de pyrimidone et compositions pharmaceutiques contenant lesdits composes | |
DK0691967T3 (da) | Nitrogenholdige kondenserede heterocykliske forbindelser | |
NO20062474L (no) | Antivirale midler bestaende av diazaindol-dikarbonyl-piperazinyl | |
CA2337825A1 (en) | Disubstituted bicyclic heterocycles, the preparation thereof and their use as pharmaceutical compositions | |
HK1089746A1 (en) | Amino alcohol derivatives, pharmaceutical compositions containing the same, and use thereof | |
WO2007137676A3 (de) | Aufhell- und/oder färbemittel mit cyclischen harnstoffderivaten | |
MY140963A (en) | Phenylpyridylpiperazine compounds | |
AU2058402A (en) | Use of lipopeptides or lipoproteins for treating lung infections and lung tumours | |
TH82581B (th) | สารสำหรับป้องกันหรือรักษาโรคเส้นประสาท | |
TH79810B (th) | สารประกอบไพริดาซิโนน | |
TH79810A (th) | สารประกอบไพริดาซิโนน |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
MM4A | Annulment or lapse of patent due to non-payment of fees |