EA200970720A1 - Средство для лечения рассеянного склероза - Google Patents

Средство для лечения рассеянного склероза

Info

Publication number
EA200970720A1
EA200970720A1 EA200970720A EA200970720A EA200970720A1 EA 200970720 A1 EA200970720 A1 EA 200970720A1 EA 200970720 A EA200970720 A EA 200970720A EA 200970720 A EA200970720 A EA 200970720A EA 200970720 A1 EA200970720 A1 EA 200970720A1
Authority
EA
Eurasian Patent Office
Prior art keywords
multiple sclerosis
treatment
prophylactic
drug
pyridazin
Prior art date
Application number
EA200970720A
Other languages
English (en)
Inventor
Масаки Ямаби
Юйтиро Табуноки
Тосиюки Едано
Original Assignee
Кова Ко., Лтд.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Кова Ко., Лтд. filed Critical Кова Ко., Лтд.
Publication of EA200970720A1 publication Critical patent/EA200970720A1/ru

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50Pyridazines; Hydrogenated pyridazines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D237/00Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/02Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
    • C07D237/06Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D237/10Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D237/14Oxygen atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Предоставлено профилактическое и/или лекарственное средство при рассеянном склерозе, которое имеет высокую эффективность в отношении рассеянного склероза, абсолютно безопасно и может приниматься перорально. Изобретение предоставляет профилактическое и/или лекарственное средство при рассеянном склерозе, содержащее, в качестве активного ингредиента, 2-бензил-5-(4-хлорофенил)-6-[4-(метилтио)фенил]-2Н-пиридазин-3-он или его сольват.
EA200970720A 2007-01-29 2008-01-28 Средство для лечения рассеянного склероза EA200970720A1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2007017328 2007-01-29
PCT/JP2008/000099 WO2008093495A1 (ja) 2007-01-29 2008-01-28 多発性硬化症治療剤

Publications (1)

Publication Number Publication Date
EA200970720A1 true EA200970720A1 (ru) 2009-12-30

Family

ID=39673809

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200970720A EA200970720A1 (ru) 2007-01-29 2008-01-28 Средство для лечения рассеянного склероза

Country Status (12)

Country Link
US (1) US20100075972A1 (ru)
EP (1) EP2127653A1 (ru)
JP (1) JPWO2008093495A1 (ru)
KR (1) KR20090114371A (ru)
CN (1) CN101600435A (ru)
AU (1) AU2008211480A1 (ru)
BR (1) BRPI0805841A2 (ru)
CA (1) CA2669563A1 (ru)
EA (1) EA200970720A1 (ru)
MX (1) MX2009008059A (ru)
TW (1) TW200838535A (ru)
WO (1) WO2008093495A1 (ru)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2307111C (en) 1997-11-19 2009-06-30 Kowa Co., Ltd. Novel pyridazine derivatives and drugs containing the same as the active ingredient
US20030225081A1 (en) * 2000-09-18 2003-12-04 Satoshi Nagato Pyridazinones and triazinones and medicinal use thereof

Also Published As

Publication number Publication date
CA2669563A1 (en) 2008-08-07
MX2009008059A (es) 2009-08-12
AU2008211480A1 (en) 2008-08-07
JPWO2008093495A1 (ja) 2010-05-20
EP2127653A1 (en) 2009-12-02
US20100075972A1 (en) 2010-03-25
TW200838535A (en) 2008-10-01
CN101600435A (zh) 2009-12-09
KR20090114371A (ko) 2009-11-03
WO2008093495A1 (ja) 2008-08-07
BRPI0805841A2 (pt) 2011-08-30

Similar Documents

Publication Publication Date Title
NO20063958L (no) HIV integrase inhibitorer
UA108087C2 (ru) Твердые формы n-(4-(7-азабицикло[2.2.1]гептан-7-ил)-2-(трифторметил)фенил)-4-оксо-5-(трифторметил)-1,4-дигидрохинолин-3-карбоксамида
CY1116509T1 (el) Θεραπευτικος συνδυασμος που περιλαμβανει ντολουτεγκραβιρη, αβακαβιρη και λαμιβουδινη
MX2009006535A (es) Derivados de indol-4-il-pirimidinil-2-il-amina y su uso como inhibidores de cinasa dependiente de ciclina.
ATE447559T1 (de) 4-(phenylamino)-6-oxo-1,6-dihydropyridazine-3- carboxamid derivate als mek inhibitoren zur behandlung von hyperproliferativen erkrankungen
WO2005089738A3 (en) Use and administration of bacterial efflux pump inhibitors
NO20072443L (no) Fungicide aktive ingredienskombinasjoner
EA201390609A1 (ru) ПРОИЗВОДНЫЕ ГИДАНТОИНА, ПОЛЕЗНЫЕ В КАЧЕСТВЕ ИНГИБИТОРОВ Kv3-КАНАЛОВ
NO20073105L (no) Pyridazinonforbindelser
NO20092569L (no) Inhibitorer av Akt-aktivitet
TN2009000446A1 (en) P70 s6 kinase inhibitors
NO20084749L (no) Organiske forbindelser og deres anvendelser
WO2011113060A3 (en) Antiviral compounds and methods of use thereof
DK3292867T3 (da) Ny brug af triazol(4,5-d)pyrimidinderivater til brug i forebyggelsen og behandlingen af bakteriel infektion
EA201170828A1 (ru) Конденсированные гетероциклические производные оксадиазола, подходящие для лечения рассеянного склероза
DK1610787T3 (da) Synergistisk kombination der omfatter roflumilast og et antikolinergt middel der er valgt blandt tiotropiumsalte til behandling af respiratoriske sygdomme
IL280755A (en) Compounds 1-methyl-4-[(4-phenylphenyl)sulfonylmethyl]cyclohexanol and 1-methyl-4-[[4-(2-pyridyl)phenyl]sulfonylmethyl]cyclohexanol and their therapeutic use
WO2004099165A3 (en) Heterocyclic compounds and hydro isomers thereof
EA201891240A1 (ru) 1,3,4-тиадиазольные соединения и их применение в лечении рака
PH12020550673A1 (en) Pyrazolopyrimidines having activity against the respiratory syncytial virus (rsv)
EA201792558A1 (ru) Противогрибковый 4-(4-(4-(((3r,5r)-5-((1h-1,2,4-триазол-1-ил)метил)-5-(2,4-дифторфенил)тетрагидрофуран-3-ил)метокси)-3-метилфенил)пиперазин-1-ил)-n-(2-гидроксициклогексил)бензамид или его фармацевтически приемлемая соль
EA200970720A1 (ru) Средство для лечения рассеянного склероза
DK2089030T3 (da) Middel til profylakse eller behandling af alkoholafhængighed eller lægemiddelafhængighed
HK1087638A1 (en) Use of tyrosine kinase inhibitors to treat diabetes
WO2012102560A3 (ko) 신규한 4-o-메틸호노키올 유도체 및 이를 유효성분으로 포함하는 염증질환 치료용 조성물