DK1610787T3 - Synergistisk kombination der omfatter roflumilast og et antikolinergt middel der er valgt blandt tiotropiumsalte til behandling af respiratoriske sygdomme - Google Patents

Synergistisk kombination der omfatter roflumilast og et antikolinergt middel der er valgt blandt tiotropiumsalte til behandling af respiratoriske sygdomme

Info

Publication number
DK1610787T3
DK1610787T3 DK04723608T DK04723608T DK1610787T3 DK 1610787 T3 DK1610787 T3 DK 1610787T3 DK 04723608 T DK04723608 T DK 04723608T DK 04723608 T DK04723608 T DK 04723608T DK 1610787 T3 DK1610787 T3 DK 1610787T3
Authority
DK
Denmark
Prior art keywords
roflumilast
treatment
agent selected
respiratory diseases
anticholinergic agent
Prior art date
Application number
DK04723608T
Other languages
English (en)
Inventor
Daniela Bundschuh
Stefan-Lutz Wollin
Christian Weimar
Original Assignee
Nycomed Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nycomed Gmbh filed Critical Nycomed Gmbh
Application granted granted Critical
Publication of DK1610787T3 publication Critical patent/DK1610787T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK04723608T 2003-03-28 2004-03-26 Synergistisk kombination der omfatter roflumilast og et antikolinergt middel der er valgt blandt tiotropiumsalte til behandling af respiratoriske sygdomme DK1610787T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP03007104 2003-03-28
PCT/EP2004/050376 WO2004084896A1 (en) 2003-03-28 2004-03-26 Synergistic combination comprising roflumilast and an anticholinergic agent selected from ipratropium, oxitropium and tiotropium salts for the treatment of respiratory diseases

Publications (1)

Publication Number Publication Date
DK1610787T3 true DK1610787T3 (da) 2008-06-02

Family

ID=33040925

Family Applications (1)

Application Number Title Priority Date Filing Date
DK04723608T DK1610787T3 (da) 2003-03-28 2004-03-26 Synergistisk kombination der omfatter roflumilast og et antikolinergt middel der er valgt blandt tiotropiumsalte til behandling af respiratoriske sygdomme

Country Status (13)

Country Link
US (1) US20060147382A1 (da)
EP (1) EP1610787B1 (da)
AT (1) ATE384529T1 (da)
CA (1) CA2519679C (da)
CY (1) CY1110373T1 (da)
DE (1) DE602004011494T2 (da)
DK (1) DK1610787T3 (da)
ES (1) ES2300755T3 (da)
MX (1) MXPA05010160A (da)
PL (1) PL1610787T3 (da)
PT (1) PT1610787E (da)
SI (1) SI1610787T1 (da)
WO (1) WO2004084896A1 (da)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2165768B1 (es) 1999-07-14 2003-04-01 Almirall Prodesfarma Sa Nuevos derivados de quinuclidina y composiciones farmaceuticas que los contienen.
MY140561A (en) 2002-02-20 2009-12-31 Nycomed Gmbh Dosage form containing pde 4 inhibitor as active ingredient
US7470791B2 (en) 2003-03-10 2008-12-30 Nycomed Gmbh Process for the preparation of roflumilast
US20050026887A1 (en) * 2003-07-29 2005-02-03 Boehringer Ingelheim International Gmbh Medicaments for inhalation comprising an anticholinergic and a steroid
SI1713473T1 (sl) * 2004-02-06 2013-06-28 Meda Pharma Gmbh & Co. Kg Kombinacija antiholinergikov in glukokortikoidov za dolgotranjno zdravljenje astme in KOPB
CA2550848C (en) * 2004-02-06 2013-02-26 Meda Pharma Gmbh & Co. Kg Combination of anticholinergics and inhibitors of phosphodiesterase type 4 for the treatment of respiratory diseases
AU2005247105B2 (en) * 2004-05-31 2010-11-11 Laboratorios Almirall, S.A. Combinations comprising antimuscarinic agents and corticosteroids
ES2257152B1 (es) * 2004-05-31 2007-07-01 Laboratorios Almirall S.A. Combinaciones que comprenden agentes antimuscarinicos y agonistas beta-adrenergicos.
SI1863476T1 (sl) * 2005-03-16 2016-05-31 Meda Pharma Gmbh & Co. Kg Kombinacija antiholinergikov in antagonistov receptorja levkotriena za zdravljenje respiratornih bolezni
ES2421916T3 (es) * 2005-03-16 2013-09-06 Nycomed Gmbh Forma farmacéutica de sabor enmascarado que contiene roflumilast
US20060219242A1 (en) * 2005-03-30 2006-10-05 Boehringer Ingelheim International Method for the Administration of an Anticholinergic by Inhalation
EP1931338A4 (en) * 2005-09-28 2009-05-27 Merck Frosst Canada Inc AEROSOL POWDER FORMULATION COMPRISING A TAMISED LACTOSE
SI1971369T1 (sl) 2005-12-21 2009-12-31 Meda Pharma Gmbh & Co Kg Kombinacija R,R-glikopirolata,roliprama in budezonida za zdravljenje vnetnih bolezni
EP2100599A1 (en) 2008-03-13 2009-09-16 Laboratorios Almirall, S.A. Inhalation composition containing aclidinium for treatment of asthma and chronic obstructive pulmonary disease
EP2100598A1 (en) 2008-03-13 2009-09-16 Laboratorios Almirall, S.A. Inhalation composition containing aclidinium for treatment of asthma and chronic obstructive pulmonary disease
EP2510928A1 (en) 2011-04-15 2012-10-17 Almirall, S.A. Aclidinium for use in improving the quality of sleep in respiratory patients

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE59911149D1 (de) * 1998-07-24 2004-12-30 Jago Res Ag Muttenz Medizinische aerosolformulierungen
US20020052312A1 (en) * 2000-05-30 2002-05-02 Reiss Theodore F. Combination therapy of chronic obstructive pulmonary disease using muscarinic receptor antagonists
US20020193393A1 (en) * 2001-03-07 2002-12-19 Michel Pairet Pharmaceutical compositions based on anticholinergics and PDE-IV inhibitors
DE10110772A1 (de) * 2001-03-07 2002-09-12 Boehringer Ingelheim Pharma Neue Arzneimittelkompositionen auf der Basis von Anticholinergika und PDE-IV-Inhibitoren
BR0209992A (pt) * 2001-05-25 2004-04-06 Pfizer Inibidor de pde4 e um agente anticolinérgico em combinação para o tratamento de doenças obstrutivas das vias respiratórias
AU2002314102A1 (en) * 2001-05-25 2002-12-09 Boehringer Ingelheim Pharma Gmbh & Co. Kg Combination of a pde4 inhibitor and tiotropium or derivate thereof for treating obstructive airways
GB0118373D0 (en) * 2001-07-27 2001-09-19 Glaxo Group Ltd Novel therapeutic method
US20050107420A1 (en) * 2002-05-23 2005-05-19 Boehringe Ingelheim Pharma Gmbh & Co. Kg Combination of a PDE4 inhibitor and tiotropium or derivative thereof for treating obstructive airways and other inflammatory diseases

Also Published As

Publication number Publication date
CA2519679C (en) 2012-08-28
WO2004084896A1 (en) 2004-10-07
EP1610787A1 (en) 2006-01-04
EP1610787B1 (en) 2008-01-23
ES2300755T3 (es) 2008-06-16
DE602004011494D1 (de) 2008-03-13
PT1610787E (pt) 2008-04-23
ATE384529T1 (de) 2008-02-15
SI1610787T1 (sl) 2008-06-30
CA2519679A1 (en) 2004-10-07
DE602004011494T2 (de) 2009-01-22
MXPA05010160A (es) 2005-11-16
CY1110373T1 (el) 2015-04-29
PL1610787T3 (pl) 2008-07-31
US20060147382A1 (en) 2006-07-06

Similar Documents

Publication Publication Date Title
CY1110373T1 (el) Συνεργιστικος συνδυασμος που περιλαμβανει ροφλουμιλαστη και εναν αντιχολινεργικο παραγοντα που επιλεγεται απο αλατα τιοτροπιου για την θεραπεια αναπνευστικων ασθενειων
LTC1781298I2 (lt) Farmacinės kompozicijos, turinčios benzoksazino, skirtos respiracinių ligų gydymui
UA109878C2 (uk) Похідні ізохінолінону, фармацевтична композиція на їх основі (варіанти) та спосіб лікування захворювань (варіанти)
EA200970447A1 (ru) Соединения и композиции в качестве ингибиторов протеинкиназы
NO20074943L (no) Roflumilast for behandlingen av diabetes mellitus
MY140826A (en) Substituted pyrazoline compounds, their preparation and use as medicaments.
DK2026803T3 (da) Sammensætninger af R(+) og S(-) pramipexol og fremgangsmåder til anvendelse heraf
DK1855677T3 (da) 3,11 B-CIS-dihydrotetrabanezin til behandling af skizofreni og andre psykoser
GEP20084452B (en) Sulfonamide derivatives for the treatment of diseases
DK1519724T3 (da) Fredericamycin-derivater som lægemidler til behandling af tumorer
NO20064547L (no) Fremgangsmater for behandling av HIV infeksjon
TW200745043A (en) Substituted pyrazoline compounds, their preparation and use as medicaments
NO20081844L (no) Terapeutiske forbindelser
EA200601837A1 (ru) Бензоксазины для лечения заболеваний дыхательных путей
MX2007007027A (es) Derivados piperazinilpiridina como agentes anti-obesidad.
NO20091955L (no) Antivirale sammensetninger, og fremgangsmater for anvendelse
DK1906916T3 (da) Oftalmisk suspension, der omfatter et oftalmisk lægemiddel, en poloxamin og et tonicitetsregulerende glycolbaseret middel, anvendelse af sammensætningen til fremstilling af et medikament til behandling af oftalmiske lidelser
EA201001747A1 (ru) Бензоксазиноновые производные, действующие в качестве агониста бета-2-адренорецептора, для лечения респираторных расстройств
MX2020010697A (es) Kit, composicion y terapia de combinacion para el sindrome del cromosoma x fragil.
MX2009010374A (es) Derivados de tetrahidro-naftalenamina sustituidos con heterociclilo, su preparacion y su uso como medicamentos.
DK1614419T3 (da) Midler til forebyggelse/behandling af retinale nervesygdomme, indeholdende alkyletherderivater eller salte deraf
MXPA05010161A (es) Combinacion sinergistica que comprende roflumilast y un agente anticolinergico seleccionado a partir de sales de ipratropio, oxitropio y tiotropio para el tratamiento de enfermedades respiratorias.
DK1651270T3 (da) Medikamenter til inhalation omfattende betamimetika og et anticholinergikum
TW200745042A (en) Substituted pyrazoline compounds, their preparation and use as medicaments
CY1119483T1 (el) Θεραπευτικος παραγων για τις αγχωδεις διαταραχες