PL1610787T3 - Synergiczna kombinacja zawierająca roflumilast i środek antycholinergiczny wybrany z soli tiotropium do leczenia chorób układu oddechowego - Google Patents
Synergiczna kombinacja zawierająca roflumilast i środek antycholinergiczny wybrany z soli tiotropium do leczenia chorób układu oddechowegoInfo
- Publication number
- PL1610787T3 PL1610787T3 PL04723608T PL04723608T PL1610787T3 PL 1610787 T3 PL1610787 T3 PL 1610787T3 PL 04723608 T PL04723608 T PL 04723608T PL 04723608 T PL04723608 T PL 04723608T PL 1610787 T3 PL1610787 T3 PL 1610787T3
- Authority
- PL
- Poland
- Prior art keywords
- roflumilast
- treatment
- agent selected
- respiratory diseases
- anticholinergic agent
- Prior art date
Links
- 229940121948 Muscarinic receptor antagonist Drugs 0.000 title abstract 2
- 239000000812 cholinergic antagonist Substances 0.000 title abstract 2
- 208000023504 respiratory system disease Diseases 0.000 title abstract 2
- MNDBXUUTURYVHR-UHFFFAOYSA-N roflumilast Chemical compound FC(F)OC1=CC=C(C(=O)NC=2C(=CN=CC=2Cl)Cl)C=C1OCC1CC1 MNDBXUUTURYVHR-UHFFFAOYSA-N 0.000 title abstract 2
- 229960002586 roflumilast Drugs 0.000 title abstract 2
- LERNTVKEWCAPOY-DZZGSBJMSA-N tiotropium Chemical class O([C@H]1C[C@@H]2[N+]([C@H](C1)[C@@H]1[C@H]2O1)(C)C)C(=O)C(O)(C=1SC=CC=1)C1=CC=CS1 LERNTVKEWCAPOY-DZZGSBJMSA-N 0.000 title abstract 2
- 239000011885 synergistic combination Substances 0.000 title 1
- OEXHQOGQTVQTAT-JRNQLAHRSA-N ipratropium Chemical compound O([C@H]1C[C@H]2CC[C@@H](C1)[N@@+]2(C)C(C)C)C(=O)C(CO)C1=CC=CC=C1 OEXHQOGQTVQTAT-JRNQLAHRSA-N 0.000 abstract 1
- 229960001888 ipratropium Drugs 0.000 abstract 1
- NVOYVOBDTVTBDX-PMEUIYRNSA-N oxitropium Chemical compound CC[N+]1(C)[C@H]2C[C@@H](C[C@@H]1[C@H]1O[C@@H]21)OC(=O)[C@H](CO)C1=CC=CC=C1 NVOYVOBDTVTBDX-PMEUIYRNSA-N 0.000 abstract 1
- 229960000797 oxitropium Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP03007104 | 2003-03-28 | ||
| PCT/EP2004/050376 WO2004084896A1 (en) | 2003-03-28 | 2004-03-26 | Synergistic combination comprising roflumilast and an anticholinergic agent selected from ipratropium, oxitropium and tiotropium salts for the treatment of respiratory diseases |
| EP04723608A EP1610787B1 (en) | 2003-03-28 | 2004-03-26 | Synergistic combination comprising roflumilast and an anticholinergic agent selected from tiotropium salts for the treatment of respiratory diseases |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL1610787T3 true PL1610787T3 (pl) | 2008-07-31 |
Family
ID=33040925
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL04723608T PL1610787T3 (pl) | 2003-03-28 | 2004-03-26 | Synergiczna kombinacja zawierająca roflumilast i środek antycholinergiczny wybrany z soli tiotropium do leczenia chorób układu oddechowego |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US20060147382A1 (pl) |
| EP (1) | EP1610787B1 (pl) |
| AT (1) | ATE384529T1 (pl) |
| CA (1) | CA2519679C (pl) |
| CY (1) | CY1110373T1 (pl) |
| DE (1) | DE602004011494T2 (pl) |
| DK (1) | DK1610787T3 (pl) |
| ES (1) | ES2300755T3 (pl) |
| MX (1) | MXPA05010160A (pl) |
| PL (1) | PL1610787T3 (pl) |
| PT (1) | PT1610787E (pl) |
| SI (1) | SI1610787T1 (pl) |
| WO (1) | WO2004084896A1 (pl) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2165768B1 (es) | 1999-07-14 | 2003-04-01 | Almirall Prodesfarma Sa | Nuevos derivados de quinuclidina y composiciones farmaceuticas que los contienen. |
| MY140561A (en) * | 2002-02-20 | 2009-12-31 | Nycomed Gmbh | Dosage form containing pde 4 inhibitor as active ingredient |
| SI1606261T1 (sl) | 2003-03-10 | 2010-03-31 | Nycomed Gmbh | Novi postopek za pripravo roflumilasta |
| US20050026887A1 (en) * | 2003-07-29 | 2005-02-03 | Boehringer Ingelheim International Gmbh | Medicaments for inhalation comprising an anticholinergic and a steroid |
| HRP20120286T1 (hr) * | 2004-02-06 | 2012-04-30 | Meda Pharma Gmbh & Co. Kg | Kombinacija antikolinergika i inhibitora fosfodiesteraze tip 4 za liječenje respiratornih bolesti |
| JP4819699B2 (ja) * | 2004-02-06 | 2011-11-24 | メダ ファーマ ゲゼルシャフト ミット ベシュレンクテル ハフツング ウント コンパニー コマンディト ゲゼルシャフト | 喘息及びｃｏｐｄの長期間の治療のための抗コリン作用薬及びグルココルチコイドの組合せ剤 |
| RU2379033C2 (ru) * | 2004-05-31 | 2010-01-20 | Лабораториос Альмираль, С.А. | Комбинации, содержащие антимускариновые средства и бета-адренергические агонисты |
| ES2257152B1 (es) * | 2004-05-31 | 2007-07-01 | Laboratorios Almirall S.A. | Combinaciones que comprenden agentes antimuscarinicos y agonistas beta-adrenergicos. |
| CN101128196B (zh) * | 2005-03-16 | 2013-01-02 | Meda制药有限及两合公司 | 用于治疗呼吸系统疾病的抗胆碱能药和白三烯受体拮抗剂的组合 |
| US8663694B2 (en) * | 2005-03-16 | 2014-03-04 | Takeda Gmbh | Taste masked dosage form containing roflumilast |
| US20060219242A1 (en) * | 2005-03-30 | 2006-10-05 | Boehringer Ingelheim International | Method for the Administration of an Anticholinergic by Inhalation |
| CA2623882A1 (en) * | 2005-09-28 | 2007-04-05 | Merck Frosst Canada Ltd. | Aerosol powder formulation comprising sieved lactose |
| DE602006008665D1 (de) | 2005-12-21 | 2009-10-01 | Meda Pharma Gmbh & Co Kg | Kombination von r,r-glycopyrrolat, rolipram und budesonid zur behandlung von entzündungskrankheiten |
| EP2100599A1 (en) | 2008-03-13 | 2009-09-16 | Laboratorios Almirall, S.A. | Inhalation composition containing aclidinium for treatment of asthma and chronic obstructive pulmonary disease |
| EP2100598A1 (en) | 2008-03-13 | 2009-09-16 | Laboratorios Almirall, S.A. | Inhalation composition containing aclidinium for treatment of asthma and chronic obstructive pulmonary disease |
| EP2510928A1 (en) | 2011-04-15 | 2012-10-17 | Almirall, S.A. | Aclidinium for use in improving the quality of sleep in respiratory patients |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6585958B1 (en) * | 1998-07-24 | 2003-07-01 | Jago Research Ag | Medicinal aerosol formulations |
| US20020052312A1 (en) * | 2000-05-30 | 2002-05-02 | Reiss Theodore F. | Combination therapy of chronic obstructive pulmonary disease using muscarinic receptor antagonists |
| DE10110772A1 (de) * | 2001-03-07 | 2002-09-12 | Boehringer Ingelheim Pharma | Neue Arzneimittelkompositionen auf der Basis von Anticholinergika und PDE-IV-Inhibitoren |
| US20020193393A1 (en) * | 2001-03-07 | 2002-12-19 | Michel Pairet | Pharmaceutical compositions based on anticholinergics and PDE-IV inhibitors |
| SK14312003A3 (sk) * | 2001-05-25 | 2004-08-03 | Pfizer Inc. | Inhibítor PDE4 a anticholinergné činidlo v kombinácii na liečbu obštrukčných chorôb dýchacích ciest |
| DE60216588T2 (de) * | 2001-05-25 | 2007-09-20 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Kombination eines pde4-inhibitors mit tiotropium zur behandlung obstruktiver atemwegserkrankungen |
| GB0118373D0 (en) * | 2001-07-27 | 2001-09-19 | Glaxo Group Ltd | Novel therapeutic method |
| US20050107420A1 (en) * | 2002-05-23 | 2005-05-19 | Boehringe Ingelheim Pharma Gmbh & Co. Kg | Combination of a PDE4 inhibitor and tiotropium or derivative thereof for treating obstructive airways and other inflammatory diseases |
-
2004
- 2004-03-26 CA CA2519679A patent/CA2519679C/en not_active Expired - Fee Related
- 2004-03-26 EP EP04723608A patent/EP1610787B1/en not_active Expired - Lifetime
- 2004-03-26 AT AT04723608T patent/ATE384529T1/de active
- 2004-03-26 US US10/550,192 patent/US20060147382A1/en not_active Abandoned
- 2004-03-26 DK DK04723608T patent/DK1610787T3/da active
- 2004-03-26 ES ES04723608T patent/ES2300755T3/es not_active Expired - Lifetime
- 2004-03-26 PT PT04723608T patent/PT1610787E/pt unknown
- 2004-03-26 PL PL04723608T patent/PL1610787T3/pl unknown
- 2004-03-26 MX MXPA05010160A patent/MXPA05010160A/es active IP Right Grant
- 2004-03-26 DE DE602004011494T patent/DE602004011494T2/de not_active Expired - Lifetime
- 2004-03-26 WO PCT/EP2004/050376 patent/WO2004084896A1/en not_active Ceased
- 2004-03-26 SI SI200430665T patent/SI1610787T1/sl unknown
-
2008
- 2008-03-27 CY CY20081100350T patent/CY1110373T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP1610787A1 (en) | 2006-01-04 |
| SI1610787T1 (sl) | 2008-06-30 |
| CY1110373T1 (el) | 2015-04-29 |
| EP1610787B1 (en) | 2008-01-23 |
| ATE384529T1 (de) | 2008-02-15 |
| PT1610787E (pt) | 2008-04-23 |
| CA2519679C (en) | 2012-08-28 |
| CA2519679A1 (en) | 2004-10-07 |
| ES2300755T3 (es) | 2008-06-16 |
| WO2004084896A1 (en) | 2004-10-07 |
| DE602004011494D1 (de) | 2008-03-13 |
| MXPA05010160A (es) | 2005-11-16 |
| DK1610787T3 (da) | 2008-06-02 |
| US20060147382A1 (en) | 2006-07-06 |
| DE602004011494T2 (de) | 2009-01-22 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CY1110373T1 (el) | Συνεργιστικος συνδυασμος που περιλαμβανει ροφλουμιλαστη και εναν αντιχολινεργικο παραγοντα που επιλεγεται απο αλατα τιοτροπιου για την θεραπεια αναπνευστικων ασθενειων | |
| MY140826A (en) | Substituted pyrazoline compounds, their preparation and use as medicaments. | |
| SG150531A1 (en) | Use of meloxicam for the treatment of respiratory diseases in pigs | |
| MX2010002498A (es) | Metodos para tratar o prevenir la infeccion del tracto respiratorio que comprende la administracion de colecalciferol. | |
| NZ616806A (en) | Pharmaceutical compositions comprising sulbactam and beta-lactamase inhibitor | |
| UA92000C2 (en) | 1-benzylindole-2-carboxamide derivatives | |
| TNSN04203A1 (en) | Benzoxazinone-derived compounds, their preparation and use as medicaments | |
| WO2009025785A3 (en) | Cb2 receptor ligands for the treatment of pain | |
| TW200745043A (en) | Substituted pyrazoline compounds, their preparation and use as medicaments | |
| TNSN07263A1 (en) | Substituted 4-phenyl tetrahydroisoquinolines, methods for producing them, their use as drug, and drug containing them | |
| MXPA05010161A (es) | Combinacion sinergistica que comprende roflumilast y un agente anticolinergico seleccionado a partir de sales de ipratropio, oxitropio y tiotropio para el tratamiento de enfermedades respiratorias. | |
| MX2009010374A (es) | Derivados de tetrahidro-naftalenamina sustituidos con heterociclilo, su preparacion y su uso como medicamentos. | |
| WO2008070010A3 (en) | Hydroxylamine derivatives for the treatment of stroke | |
| TW200738699A (en) | 4-Substituted pyrazoline compounds, their preparation and use as medicaments | |
| NZ602807A (en) | 4-amino-5-fluoro-3-[6-(4-methylpiperazin-1-yl)-1h-benzimidazol-2-yl]-1h-quinolin-2-one and an mtor inhibitor | |
| MX2008008556A (es) | Derivados de triterpenoquinonas y triterpenofenoles y su aplicacion para el tratamiento de tumores y enfermedades parasitarias. | |
| WO2008004100A3 (en) | Therapeutic compounds | |
| WO2007104933A8 (en) | Chemical compounds | |
| TW200635595A (en) | Medicaments for the treatment of prevention of fibrotic diseases | |
| MX2009005912A (es) | Derivados de etilamina-fenilo heterociclilo sustituidos, su preparacion y uso como medicamentos. | |
| TW200745042A (en) | Substituted pyrazoline compounds, their preparation and use as medicaments | |
| MX2008013477A (es) | Compuestos biciclicos de tetrahidropirrol. | |
| WO2005080549A3 (de) | Trioxacarcine und deren verwendung gegen infektionskrankheiten | |
| UA83017C2 (uk) | Комбінація рофлуміласту та r,r-формотеролу для лікування захворювань дихальних шляхів | |
| GB0313386D0 (en) | Treatment of disease |