TW222626B - - Google Patents

Info

Publication number
TW222626B
TW222626B TW081105174A TW81105174A TW222626B TW 222626 B TW222626 B TW 222626B TW 081105174 A TW081105174 A TW 081105174A TW 81105174 A TW81105174 A TW 81105174A TW 222626 B TW222626 B TW 222626B
Authority
TW
Taiwan
Application number
TW081105174A
Other languages
Chinese (zh)
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Application granted granted Critical
Publication of TW222626B publication Critical patent/TW222626B/zh

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/10Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing aromatic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D263/00Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/30Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D263/32Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02Silicon compounds
    • C07F7/08Compounds having one or more C—Si linkages
    • C07F7/18Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804Compounds having Si-O-C linkages

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
TW081105174A 1991-07-22 1992-06-30 TW222626B (enExample)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US73377191A 1991-07-22 1991-07-22

Publications (1)

Publication Number Publication Date
TW222626B true TW222626B (enExample) 1994-04-21

Family

ID=24949048

Family Applications (1)

Application Number Title Priority Date Filing Date
TW081105174A TW222626B (enExample) 1991-07-22 1992-06-30

Country Status (19)

Country Link
US (1) US6329408B1 (enExample)
EP (1) EP0641338A1 (enExample)
JP (1) JPH08823B2 (enExample)
CN (1) CN1030195C (enExample)
AU (1) AU665775B2 (enExample)
BR (1) BR9206293A (enExample)
CA (1) CA2111447C (enExample)
CZ (1) CZ282831B6 (enExample)
HU (1) HUT69692A (enExample)
IE (1) IE922357A1 (enExample)
IL (1) IL102573A (enExample)
MX (1) MX9204279A (enExample)
NO (1) NO301226B1 (enExample)
NZ (1) NZ243653A (enExample)
PT (1) PT100711B (enExample)
RU (1) RU2079497C1 (enExample)
TW (1) TW222626B (enExample)
WO (1) WO1993002079A1 (enExample)
ZA (1) ZA925468B (enExample)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE173728T1 (de) * 1991-07-22 1998-12-15 Pfizer Verfahren zur herstellung von (s)-4-(3-(5-methyl- 2-phenyl-4-oxazolyl)- 1-hydroxypropyl> brombenzol
GB9308487D0 (en) * 1993-04-23 1993-06-09 Smithkline Beecham Plc Novel compounds
CA2294385C (en) 1997-06-18 2007-06-05 Smithkline Beecham P.L.C. Treatment of diabetes with thiazolidinedione and sulphonylurea
AR023700A1 (es) 1998-11-12 2002-09-04 Smithkline Beecham Plc Un procedimiento para preparar una composicion farmaceutica que comprende un sensibilizador de insulina
WO2000028989A1 (en) 1998-11-12 2000-05-25 Smithkline Beecham P.L.C. Pharmaceutical composition for modified release of an insulin sensitiser and another antidiabetic agent
CZ20013833A3 (cs) * 1999-04-28 2002-02-13 Aventis Pharma Deutschland Gmbh Deriváty kyselin se dvěma arylovými zbytky jako ligandy receptorů PPAR a farmaceutické prostředky, které je obsahují
TWI260321B (en) * 1999-09-22 2006-08-21 Bristol Myers Squibb Co Substituted acid derivatives useful as antidiabetic and antiobesity agents and method
EP1228067B1 (en) * 1999-11-10 2004-07-14 Takeda Chemical Industries, Ltd. 5-membered n-heterocyclic compounds with hypoglycemic and hypolipidemic activity
RU2259361C2 (ru) * 2000-05-26 2005-08-27 Ниппон Синяку Ко., Лтд. Профилактическое или терапевтическое средство и фармацевтическая композиция, содержащая гетероциклическое соединение
GB0014969D0 (en) 2000-06-19 2000-08-09 Smithkline Beecham Plc Novel method of treatment
JP2003040877A (ja) * 2001-07-24 2003-02-13 Sumika Fine Chemicals Co Ltd 5−[6−(2−フルオロベンジルオキシ)−2−ナフチル]メチル−2,4−チアゾリジンジオンの製造方法及びその精製方法
PL210408B1 (pl) * 2002-06-03 2012-01-31 Novartis Ag Zastosowanie podstawionych cyjanopirolidyn do wytwarzania leku do modulowania hiperlipidemii
CN100402510C (zh) * 2002-07-03 2008-07-16 霍夫曼-拉罗奇有限公司 噁唑衍生物及其作为胰岛素敏化剂的应用
US8268352B2 (en) 2002-08-05 2012-09-18 Torrent Pharmaceuticals Limited Modified release composition for highly soluble drugs
US8216609B2 (en) 2002-08-05 2012-07-10 Torrent Pharmaceuticals Limited Modified release composition of highly soluble drugs
CA2539554A1 (en) * 2003-09-22 2005-03-31 Ono Pharmaceutical Co., Ltd. Phenylacetic acid derivative, process for producing the same, and use
EP1586573B1 (en) * 2004-04-01 2007-02-07 Sanofi-Aventis Deutschland GmbH Oxadiazolones, processes for their preparation and their use as pharmaceuticals
US20120094959A1 (en) 2010-10-19 2012-04-19 Bonnie Blazer-Yost Treatment of cystic diseases
WO2016071727A1 (en) 2014-11-04 2016-05-12 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods for the prevention and the treatment of rapidly progressive glomerulonephritis
CN109867765A (zh) * 2019-02-28 2019-06-11 中山大学惠州研究院 一种长效缓释可降解防污聚氨酯及其制备方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5522636A (en) 1978-08-04 1980-02-18 Takeda Chem Ind Ltd Thiazoliding derivative
US4342771A (en) 1981-01-02 1982-08-03 Pfizer Inc. Hypoglycemic 5-substituted oxazolidine-2,4-diones
US4367234A (en) 1980-07-28 1983-01-04 Pfizer Inc. Hypoglycemic 5-substituted oxazolidine-2,4-diones
US4617312A (en) 1983-01-17 1986-10-14 Pfizer Inc. Aldose reductase inhibiting 5-(2-alkoxyphenyl) thiazolidinediones
CN1003445B (zh) 1984-10-03 1989-03-01 武田药品工业株式会社 噻唑烷二酮衍生物,其制备方法和用途
US4703052A (en) 1985-05-21 1987-10-27 Pfizer Inc. Hypoglycemic thiazolidinediones
FI91869C (fi) * 1987-03-18 1994-08-25 Tanabe Seiyaku Co Menetelmä antidiabeettisena aineena käytettävien bensoksatsolijohdannaisten valmistamiseksi
GB8713861D0 (en) * 1987-06-13 1987-07-15 Beecham Group Plc Compounds
WO1989008651A1 (en) * 1988-03-08 1989-09-21 Pfizer Inc. Hypoglycemic thiazolidinedione derivatives
US5036079A (en) 1989-12-07 1991-07-30 Pfizer Inc. Hypoglycemic thiazolidinedione derivatives
US5089514A (en) 1990-06-14 1992-02-18 Pfizer Inc. 3-coxazolyl [phenyl, chromanyl or benzofuranyl]-2-hydroxypropionic acid derivatives and analogs as hypoglycemic agents

Also Published As

Publication number Publication date
US6329408B1 (en) 2001-12-11
NO940225L (no) 1994-01-21
CN1030195C (zh) 1995-11-01
NO940225D0 (no) 1994-01-21
JPH08823B2 (ja) 1996-01-10
CN1068823A (zh) 1993-02-10
EP0641338A1 (en) 1995-03-08
CA2111447A1 (en) 1993-02-04
HUT69692A (en) 1995-09-28
ZA925468B (en) 1994-01-21
BR9206293A (pt) 1994-11-08
RU2079497C1 (ru) 1997-05-20
PT100711B (pt) 1999-07-30
CZ12494A3 (en) 1994-07-13
IL102573A0 (en) 1993-01-14
MX9204279A (es) 1994-03-31
AU665775B2 (en) 1996-01-18
AU2297392A (en) 1993-02-23
JPH07502487A (ja) 1995-03-16
WO1993002079A1 (en) 1993-02-04
IL102573A (en) 1997-04-15
NO301226B1 (no) 1997-09-29
IE922357A1 (en) 1993-01-27
NZ243653A (en) 1995-02-24
CA2111447C (en) 2002-08-13
HU9400181D0 (en) 1994-05-30
PT100711A (pt) 1993-09-30
CZ282831B6 (cs) 1997-10-15

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