BR9206293A - Tiazolidinadionas hipoglicêmicas e intermediários - Google Patents
Tiazolidinadionas hipoglicêmicas e intermediáriosInfo
- Publication number
- BR9206293A BR9206293A BR9206293A BR9206293A BR9206293A BR 9206293 A BR9206293 A BR 9206293A BR 9206293 A BR9206293 A BR 9206293A BR 9206293 A BR9206293 A BR 9206293A BR 9206293 A BR9206293 A BR 9206293A
- Authority
- BR
- Brazil
- Prior art keywords
- intermediates
- hypoglycemic thiazolidinediones
- thiazolidinediones
- hypoglycemic
- Prior art date
Links
- 229940123464 Thiazolidinedione Drugs 0.000 title 1
- 230000002218 hypoglycaemic effect Effects 0.000 title 1
- 239000000543 intermediate Substances 0.000 title 1
- 150000001467 thiazolidinediones Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing aromatic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D263/32—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
- C07F7/1804—Compounds having Si-O-C linkages
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Diabetes (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Medicines Containing Plant Substances (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US73377191A | 1991-07-22 | 1991-07-22 | |
| PCT/US1992/005436 WO1993002079A1 (en) | 1991-07-22 | 1992-07-01 | Hypoglycemic thiazolidinediones and intermediates |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR9206293A true BR9206293A (pt) | 1994-11-08 |
Family
ID=24949048
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR9206293A BR9206293A (pt) | 1991-07-22 | 1992-07-01 | Tiazolidinadionas hipoglicêmicas e intermediários |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US6329408B1 (enExample) |
| EP (1) | EP0641338A1 (enExample) |
| JP (1) | JPH08823B2 (enExample) |
| CN (1) | CN1030195C (enExample) |
| AU (1) | AU665775B2 (enExample) |
| BR (1) | BR9206293A (enExample) |
| CA (1) | CA2111447C (enExample) |
| CZ (1) | CZ282831B6 (enExample) |
| HU (1) | HUT69692A (enExample) |
| IE (1) | IE922357A1 (enExample) |
| IL (1) | IL102573A (enExample) |
| MX (1) | MX9204279A (enExample) |
| NO (1) | NO301226B1 (enExample) |
| NZ (1) | NZ243653A (enExample) |
| PT (1) | PT100711B (enExample) |
| RU (1) | RU2079497C1 (enExample) |
| TW (1) | TW222626B (enExample) |
| WO (1) | WO1993002079A1 (enExample) |
| ZA (1) | ZA925468B (enExample) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0595868B1 (en) * | 1991-07-22 | 1998-11-25 | Pfizer Inc. | Process for the preparation of (s)-4-[3-(5-methyl-2-phenyl-4-oxazolyl)- 1-hydroxypropyl]bromobenzene |
| GB9308487D0 (en) * | 1993-04-23 | 1993-06-09 | Smithkline Beecham Plc | Novel compounds |
| EP1671637A3 (en) | 1997-06-18 | 2007-12-19 | SmithKline Beecham P.L.C. | Treatment of diabetes with thiazolidinedione and sulphonylurea |
| DZ2937A1 (fr) | 1998-11-12 | 2004-03-15 | Smithkline Beecham Plc | Compositions nouvelles de sensibilidants à l'insuline. |
| WO2000028989A1 (en) * | 1998-11-12 | 2000-05-25 | Smithkline Beecham P.L.C. | Pharmaceutical composition for modified release of an insulin sensitiser and another antidiabetic agent |
| HRP20010795A2 (en) * | 1999-04-28 | 2003-02-28 | Aventis Pharma Gmbh | Di-aryl acid derivatives as ppar receptor ligands |
| TWI302149B (en) * | 1999-09-22 | 2008-10-21 | Bristol Myers Squibb Co | Substituted acid derivatives useful as antiodiabetic and antiobesity agents and method |
| CA2390923A1 (en) * | 1999-11-10 | 2001-05-31 | Takeda Chemical Industries, Ltd. | 5-membered n-heterocyclic compounds with hypoglycemic and hypolipidemic activity |
| IL152979A0 (en) * | 2000-05-26 | 2003-06-24 | Nippon Shinyaku Co Ltd | Heterocyclic compounds |
| GB0014969D0 (en) | 2000-06-19 | 2000-08-09 | Smithkline Beecham Plc | Novel method of treatment |
| JP2003040877A (ja) * | 2001-07-24 | 2003-02-13 | Sumika Fine Chemicals Co Ltd | ５−［６−（２−フルオロベンジルオキシ）−２−ナフチル］メチル−２，４−チアゾリジンジオンの製造方法及びその精製方法 |
| CN100402026C (zh) * | 2002-06-03 | 2008-07-16 | 诺瓦提斯公司 | 取代的氰基吡咯烷和含有它们的组合制剂用于治疗高脂血症和相关疾病的用途 |
| PL374818A1 (en) * | 2002-07-03 | 2005-10-31 | F.Hoffmann-La Roche Ag | Oxazole derivatives and their use as insulin sensitizers |
| US8216609B2 (en) | 2002-08-05 | 2012-07-10 | Torrent Pharmaceuticals Limited | Modified release composition of highly soluble drugs |
| US8268352B2 (en) | 2002-08-05 | 2012-09-18 | Torrent Pharmaceuticals Limited | Modified release composition for highly soluble drugs |
| JP4661595B2 (ja) * | 2003-09-22 | 2011-03-30 | 小野薬品工業株式会社 | フェニル酢酸誘導体、その製造方法および用途 |
| EP1586573B1 (en) * | 2004-04-01 | 2007-02-07 | Sanofi-Aventis Deutschland GmbH | Oxadiazolones, processes for their preparation and their use as pharmaceuticals |
| US20120094959A1 (en) | 2010-10-19 | 2012-04-19 | Bonnie Blazer-Yost | Treatment of cystic diseases |
| WO2016071727A1 (en) | 2014-11-04 | 2016-05-12 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Methods for the prevention and the treatment of rapidly progressive glomerulonephritis |
| CN109867765A (zh) * | 2019-02-28 | 2019-06-11 | 中山大学惠州研究院 | 一种长效缓释可降解防污聚氨酯及其制备方法 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5522636A (en) | 1978-08-04 | 1980-02-18 | Takeda Chem Ind Ltd | Thiazoliding derivative |
| US4342771A (en) | 1981-01-02 | 1982-08-03 | Pfizer Inc. | Hypoglycemic 5-substituted oxazolidine-2,4-diones |
| US4367234A (en) | 1980-07-28 | 1983-01-04 | Pfizer Inc. | Hypoglycemic 5-substituted oxazolidine-2,4-diones |
| US4617312A (en) | 1983-01-17 | 1986-10-14 | Pfizer Inc. | Aldose reductase inhibiting 5-(2-alkoxyphenyl) thiazolidinediones |
| CN1003445B (zh) | 1984-10-03 | 1989-03-01 | 武田药品工业株式会社 | 噻唑烷二酮衍生物，其制备方法和用途 |
| WO1986007056A1 (en) | 1985-05-21 | 1986-12-04 | Pfizer Inc. | Hypoglycemic thiazolidinediones |
| FI91869C (fi) * | 1987-03-18 | 1994-08-25 | Tanabe Seiyaku Co | Menetelmä antidiabeettisena aineena käytettävien bensoksatsolijohdannaisten valmistamiseksi |
| GB8713861D0 (en) * | 1987-06-13 | 1987-07-15 | Beecham Group Plc | Compounds |
| WO1989008651A1 (en) * | 1988-03-08 | 1989-09-21 | Pfizer Inc. | Hypoglycemic thiazolidinedione derivatives |
| US5036079A (en) | 1989-12-07 | 1991-07-30 | Pfizer Inc. | Hypoglycemic thiazolidinedione derivatives |
| US5089514A (en) | 1990-06-14 | 1992-02-18 | Pfizer Inc. | 3-coxazolyl [phenyl, chromanyl or benzofuranyl]-2-hydroxypropionic acid derivatives and analogs as hypoglycemic agents |
-
1992
- 1992-06-30 TW TW081105174A patent/TW222626B/zh active
- 1992-07-01 WO PCT/US1992/005436 patent/WO1993002079A1/en not_active Ceased
- 1992-07-01 BR BR9206293A patent/BR9206293A/pt not_active Application Discontinuation
- 1992-07-01 CZ CS94124A patent/CZ282831B6/cs not_active IP Right Cessation
- 1992-07-01 AU AU22973/92A patent/AU665775B2/en not_active Ceased
- 1992-07-01 JP JP5502812A patent/JPH08823B2/ja not_active Expired - Fee Related
- 1992-07-01 CA CA002111447A patent/CA2111447C/en not_active Expired - Fee Related
- 1992-07-01 EP EP92915346A patent/EP0641338A1/en not_active Withdrawn
- 1992-07-01 RU RU94012853/04A patent/RU2079497C1/ru not_active IP Right Cessation
- 1992-07-01 HU HU9400181A patent/HUT69692A/hu unknown
- 1992-07-20 PT PT100711A patent/PT100711B/pt active IP Right Grant
- 1992-07-21 CN CN92108662A patent/CN1030195C/zh not_active Expired - Fee Related
- 1992-07-21 NZ NZ243653A patent/NZ243653A/en unknown
- 1992-07-21 ZA ZA925468A patent/ZA925468B/xx unknown
- 1992-07-21 IE IE235792A patent/IE922357A1/en not_active Application Discontinuation
- 1992-07-21 MX MX9204279A patent/MX9204279A/es not_active IP Right Cessation
- 1992-07-21 IL IL102573A patent/IL102573A/xx not_active IP Right Cessation
-
1994
- 1994-01-21 NO NO940225A patent/NO301226B1/no unknown
-
1995
- 1995-06-01 US US08/458,071 patent/US6329408B1/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP0641338A1 (en) | 1995-03-08 |
| NO940225D0 (no) | 1994-01-21 |
| WO1993002079A1 (en) | 1993-02-04 |
| AU2297392A (en) | 1993-02-23 |
| AU665775B2 (en) | 1996-01-18 |
| IL102573A0 (en) | 1993-01-14 |
| RU2079497C1 (ru) | 1997-05-20 |
| CA2111447A1 (en) | 1993-02-04 |
| IL102573A (en) | 1997-04-15 |
| CZ12494A3 (en) | 1994-07-13 |
| MX9204279A (es) | 1994-03-31 |
| IE922357A1 (en) | 1993-01-27 |
| CN1030195C (zh) | 1995-11-01 |
| NO301226B1 (no) | 1997-09-29 |
| TW222626B (enExample) | 1994-04-21 |
| NO940225L (no) | 1994-01-21 |
| ZA925468B (en) | 1994-01-21 |
| JPH07502487A (ja) | 1995-03-16 |
| NZ243653A (en) | 1995-02-24 |
| HUT69692A (en) | 1995-09-28 |
| CZ282831B6 (cs) | 1997-10-15 |
| CA2111447C (en) | 2002-08-13 |
| PT100711A (pt) | 1993-09-30 |
| PT100711B (pt) | 1999-07-30 |
| JPH08823B2 (ja) | 1996-01-10 |
| CN1068823A (zh) | 1993-02-10 |
| US6329408B1 (en) | 2001-12-11 |
| HU9400181D0 (en) | 1994-05-30 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| FI20001900L (fi) | Välituotteet | |
| NO940225D0 (no) | Hypoglykemiske tiazolidindioner og mellomprodukter | |
| FI930605L (fi) | Cd40cr-receptor och ligander foer denna | |
| FI930064A0 (fi) | Anpassningsbar ekvalisator och mottagare | |
| FI931183A0 (fi) | Halvledarkondensator och mikrofonanordning | |
| FI930459L (fi) | Schampokompositioner och suspenderingsmedel foer dessa | |
| FI931085L (fi) | Antitumoerkompositioner och behandlingsmetoder | |
| FI924060A7 (fi) | Cellulaert radionaet och mobilradiostation | |
| FI930076L (fi) | Cysteamin innehaollande permanentningskomposition och foerfarande | |
| FI930831A7 (fi) | Kelatkomplex och foerfarande foer deras framstaellning | |
| FI930457L (fi) | Stabilt vaordschampo innehaollande katjoniska och suspenderade vattenoloesliga vaordmedel | |
| FI930777A7 (fi) | Foeraedling och foerfarande foer avfallspapper | |
| FI930104A7 (fi) | Verktyg foer slagborrning och meissling och verktygshaollare foer saodana verktyg | |
| FI931346L (fi) | Butadienderivat och foerfarande foer deras framstaellning | |
| FI930453L (fi) | Tumoerhaemmande kompositioner och behandlingsmetoder | |
| FI925364A0 (fi) | Foerfarande och anordning foer traodloes informationsoeverfoering | |
| FI933376A0 (fi) | 4-amino-3-acylkinolinderivater och deras anvaendning som inhibitorer avmagsyrasekretion | |
| FI935823L (fi) | Hypoglykemiska tiozolidindionfoereningar | |
| BR9205281A (pt) | Pentapeptideos imuno-reguladores e neuro-reguladores | |
| FI930180A7 (fi) | X-paket-maongkomponentenkoder och motsvarande dekoder | |
| FI940308A7 (fi) | Hypoglykeemiset tiatsolidiinidionit ja välituotteet | |
| FI931015A0 (fi) | 2-(2-substituerade pyrrolidinyltio)karbapenemderivat | |
| NO924553L (no) | Avstembar mikroboelgeoscillator | |
| SE9302321D0 (sv) | Laasbar gaeng och stiftbult | |
| FI970043A7 (fi) | Aryylialkyylipiperidiini välituotteet |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EE | Request for examination | ||
| EG | Technical examination (opinion): publication of technical examination (opinion) | ||
| FC | Decision: refusal | ||
| FC | Decision: refusal |