PT100711A - Tiazolidinadionas hipoglicemicas e compostos intermediarios - Google Patents

Tiazolidinadionas hipoglicemicas e compostos intermediarios

Info

Publication number
PT100711A
PT100711A PT100711A PT10071192A PT100711A PT 100711 A PT100711 A PT 100711A PT 100711 A PT100711 A PT 100711A PT 10071192 A PT10071192 A PT 10071192A PT 100711 A PT100711 A PT 100711A
Authority
PT
Portugal
Prior art keywords
thiazolidinadions
hypoglycemic
intermediate compounds
compounds
hypoglycemic thiazolidinadions
Prior art date
Application number
PT100711A
Other languages
English (en)
Other versions
PT100711B (pt
Inventor
David A Clark
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of PT100711A publication Critical patent/PT100711A/pt
Publication of PT100711B publication Critical patent/PT100711B/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/10Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing aromatic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D263/00Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/30Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D263/32Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02Silicon compounds
    • C07F7/08Compounds having one or more C—Si linkages
    • C07F7/18Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804Compounds having Si-O-C linkages

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Obesity (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
PT100711A 1991-07-22 1992-07-20 Tiazolidinadionas hipoglicemicas e compostos intermediarios PT100711B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US73377191A 1991-07-22 1991-07-22

Publications (2)

Publication Number Publication Date
PT100711A true PT100711A (pt) 1993-09-30
PT100711B PT100711B (pt) 1999-07-30

Family

ID=24949048

Family Applications (1)

Application Number Title Priority Date Filing Date
PT100711A PT100711B (pt) 1991-07-22 1992-07-20 Tiazolidinadionas hipoglicemicas e compostos intermediarios

Country Status (19)

Country Link
US (1) US6329408B1 (pt)
EP (1) EP0641338A1 (pt)
JP (1) JPH08823B2 (pt)
CN (1) CN1030195C (pt)
AU (1) AU665775B2 (pt)
BR (1) BR9206293A (pt)
CA (1) CA2111447C (pt)
CZ (1) CZ282831B6 (pt)
HU (1) HUT69692A (pt)
IE (1) IE922357A1 (pt)
IL (1) IL102573A (pt)
MX (1) MX9204279A (pt)
NO (1) NO301226B1 (pt)
NZ (1) NZ243653A (pt)
PT (1) PT100711B (pt)
RU (1) RU2079497C1 (pt)
TW (1) TW222626B (pt)
WO (1) WO1993002079A1 (pt)
ZA (1) ZA925468B (pt)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU660701B2 (en) * 1991-07-22 1995-07-06 Pfizer Inc. Process for the preparation of intermediates in the synthesis of chiral thiazolidine-2,4-dione derivatives
GB9308487D0 (en) * 1993-04-23 1993-06-09 Smithkline Beecham Plc Novel compounds
AP1600A (en) 1997-06-18 2006-04-28 Smithkline Beecham Plc Combination of a thiazolidinedione and a sulphonylurea for treating diabetes
BR9915285A (pt) * 1998-11-12 2001-08-07 Smithkline Beecham Plc Composição farmacêutica para liberação modificada de um sensitivador de insulina e um outro agente antidiabético
AR023699A1 (es) 1998-11-12 2002-09-04 Smithkline Beecham Corp Una composicion farmaceutica que comprende un estabilizador de insulina y un procedimiento para preparar una composicion farmaceutica
GB0014969D0 (en) 2000-06-19 2000-08-09 Smithkline Beecham Plc Novel method of treatment
JP2003040877A (ja) * 2001-07-24 2003-02-13 Sumika Fine Chemicals Co Ltd 5−[6−(2−フルオロベンジルオキシ)−2−ナフチル]メチル−2,4−チアゾリジンジオンの製造方法及びその精製方法
US8268352B2 (en) 2002-08-05 2012-09-18 Torrent Pharmaceuticals Limited Modified release composition for highly soluble drugs
US8216609B2 (en) 2002-08-05 2012-07-10 Torrent Pharmaceuticals Limited Modified release composition of highly soluble drugs
US20120094959A1 (en) 2010-10-19 2012-04-19 Bonnie Blazer-Yost Treatment of cystic diseases
US10034868B2 (en) 2014-11-04 2018-07-31 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods for the prevention and the treatment of rapidly progressive glomerulonephritis
CN109867765A (zh) * 2019-02-28 2019-06-11 中山大学惠州研究院 一种长效缓释可降解防污聚氨酯及其制备方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5522636A (en) 1978-08-04 1980-02-18 Takeda Chem Ind Ltd Thiazoliding derivative
US4367234A (en) 1980-07-28 1983-01-04 Pfizer Inc. Hypoglycemic 5-substituted oxazolidine-2,4-diones
US4342771A (en) 1981-01-02 1982-08-03 Pfizer Inc. Hypoglycemic 5-substituted oxazolidine-2,4-diones
US4617312A (en) 1983-01-17 1986-10-14 Pfizer Inc. Aldose reductase inhibiting 5-(2-alkoxyphenyl) thiazolidinediones
CN1003445B (zh) 1984-10-03 1989-03-01 武田药品工业株式会社 噻唑烷二酮衍生物,其制备方法和用途
US4703052A (en) 1985-05-21 1987-10-27 Pfizer Inc. Hypoglycemic thiazolidinediones
FI91869C (fi) * 1987-03-18 1994-08-25 Tanabe Seiyaku Co Menetelmä antidiabeettisena aineena käytettävien bensoksatsolijohdannaisten valmistamiseksi
GB8713861D0 (en) * 1987-06-13 1987-07-15 Beecham Group Plc Compounds
MX15171A (es) * 1988-03-08 1993-05-01 Pfizer Derivados de tiazolidinodiona hipoglicemicos
US5036079A (en) 1989-12-07 1991-07-30 Pfizer Inc. Hypoglycemic thiazolidinedione derivatives
US5089514A (en) 1990-06-14 1992-02-18 Pfizer Inc. 3-coxazolyl [phenyl, chromanyl or benzofuranyl]-2-hydroxypropionic acid derivatives and analogs as hypoglycemic agents

Also Published As

Publication number Publication date
HUT69692A (en) 1995-09-28
NZ243653A (en) 1995-02-24
PT100711B (pt) 1999-07-30
CA2111447A1 (en) 1993-02-04
CA2111447C (en) 2002-08-13
CN1068823A (zh) 1993-02-10
MX9204279A (es) 1994-03-31
IL102573A (en) 1997-04-15
TW222626B (pt) 1994-04-21
ZA925468B (en) 1994-01-21
RU2079497C1 (ru) 1997-05-20
HU9400181D0 (en) 1994-05-30
US6329408B1 (en) 2001-12-11
NO940225D0 (no) 1994-01-21
NO301226B1 (no) 1997-09-29
EP0641338A1 (en) 1995-03-08
BR9206293A (pt) 1994-11-08
WO1993002079A1 (en) 1993-02-04
NO940225L (no) 1994-01-21
CZ282831B6 (cs) 1997-10-15
IE922357A1 (en) 1993-01-27
CZ12494A3 (en) 1994-07-13
IL102573A0 (en) 1993-01-14
AU665775B2 (en) 1996-01-18
JPH07502487A (ja) 1995-03-16
AU2297392A (en) 1993-02-23
CN1030195C (zh) 1995-11-01
JPH08823B2 (ja) 1996-01-10

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Legal Events

Date Code Title Description
BB1A Laying open of patent application

Effective date: 19930525

FG3A Patent granted, date of granting

Effective date: 19990413