TW201831192A - 作為ｓｔｉｎｇ促效劑之環狀二核苷酸 - Google Patents

作為ｓｔｉｎｇ促效劑之環狀二核苷酸 Download PDF

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Publication number
TW201831192A
TW201831192A TW106140679A TW106140679A TW201831192A TW 201831192 A TW201831192 A TW 201831192A TW 106140679 A TW106140679 A TW 106140679A TW 106140679 A TW106140679 A TW 106140679A TW 201831192 A TW201831192 A TW 201831192A
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Taiwan
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compound
group
cancer
mixture
mmol
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TW106140679A
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English (en)
Chinese (zh)
Inventor
吉爾斯 比格南
彼得 康諾利
詹姆士 愛德華茲
斯圖爾特 伊曼紐爾
西爾維 拉奎爾
天保 魯
馬克 里區特
雷歐尼德 賓格爾曼
桑托斯 塔堤康達
廣義 王
鍾明宏
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美商健生生物科技公司
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Publication of TW201831192A publication Critical patent/TW201831192A/zh

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C07H21/02—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with ribosyl as saccharide radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7076—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7084—Compounds having two nucleosides or nucleotides, e.g. nicotinamide-adenine dinucleotide, flavine-adenine dinucleotide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Genetics & Genomics (AREA)
  • Dispersion Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicinal Preparation (AREA)
TW106140679A 2016-11-25 2017-11-23 作為ｓｔｉｎｇ促效劑之環狀二核苷酸 TW201831192A (zh)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US201662426350P 2016-11-25 2016-11-25
US62/426,350 2016-11-25
US201762502983P 2017-05-08 2017-05-08
US62/502,983 2017-05-08
US201762555232P 2017-09-07 2017-09-07
US62/555,232 2017-09-07

Publications (1)

Publication Number Publication Date
TW201831192A true TW201831192A (zh) 2018-09-01

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
TW106140679A TW201831192A (zh) 2016-11-25 2017-11-23 作為ｓｔｉｎｇ促效劑之環狀二核苷酸

Country Status (13)

Country Link
US (2) US11472830B2 (pt)
EP (1) EP3544989A1 (pt)
JP (2) JP7316936B2 (pt)
KR (1) KR20190085107A (pt)
CN (1) CN110291096A (pt)
AU (1) AU2017365158B2 (pt)
BR (1) BR112019010606A2 (pt)
CA (1) CA3044693A1 (pt)
JO (1) JOP20170188A1 (pt)
MX (1) MX2019006082A (pt)
TW (1) TW201831192A (pt)
UY (1) UY37495A (pt)
WO (1) WO2018098203A1 (pt)

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JP2020500862A (ja) 2020-01-16
BR112019010606A2 (pt) 2019-09-17
JOP20170188A1 (ar) 2019-01-30
UY37495A (es) 2018-05-31
JP7316936B2 (ja) 2023-07-28
AU2017365158B2 (en) 2022-02-17
US20180162899A1 (en) 2018-06-14
MX2019006082A (es) 2019-11-12
KR20190085107A (ko) 2019-07-17
CN110291096A (zh) 2019-09-27
CA3044693A1 (en) 2018-05-31
US20230144627A1 (en) 2023-05-11
WO2018098203A1 (en) 2018-05-31
AU2017365158A1 (en) 2019-06-06
EP3544989A1 (en) 2019-10-02
JP2022110131A (ja) 2022-07-28
US11472830B2 (en) 2022-10-18

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