TW201754B - - Google Patents

Download PDF

Info

Publication number
TW201754B
TW201754B TW079102881A TW79102881A TW201754B TW 201754 B TW201754 B TW 201754B TW 079102881 A TW079102881 A TW 079102881A TW 79102881 A TW79102881 A TW 79102881A TW 201754 B TW201754 B TW 201754B
Authority
TW
Taiwan
Prior art keywords
peptide
ala
phe
leu
gly
Prior art date
Application number
TW079102881A
Other languages
English (en)
Chinese (zh)
Original Assignee
Univ Tulane
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US07/282,328 external-priority patent/US5162497A/en
Application filed by Univ Tulane filed Critical Univ Tulane
Application granted granted Critical
Publication of TW201754B publication Critical patent/TW201754B/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/57572—Gastrin releasing peptide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/02—Linear peptides containing at least one abnormal peptide link
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • C07K7/086—Bombesin; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Veterinary Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Endocrinology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Diabetes (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
TW079102881A 1988-10-14 1990-04-11 TW201754B (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US25799888A 1988-10-14 1988-10-14
US07/282,328 US5162497A (en) 1987-09-24 1988-12-09 Bradykinin analogs with non-peptide bond
US31794189A 1989-03-02 1989-03-02
US37655589A 1989-07-07 1989-07-07
US39716989A 1989-08-21 1989-08-21

Publications (1)

Publication Number Publication Date
TW201754B true TW201754B (ja) 1993-03-11

Family

ID=27540392

Family Applications (1)

Application Number Title Priority Date Filing Date
TW079102881A TW201754B (ja) 1988-10-14 1990-04-11

Country Status (13)

Country Link
EP (1) EP0438519B1 (ja)
JP (1) JP2919889B2 (ja)
KR (1) KR900701827A (ja)
AT (1) ATE165836T1 (ja)
AU (1) AU638423B2 (ja)
DE (1) DE68928667T2 (ja)
DK (1) DK66391A (ja)
FI (1) FI104252B (ja)
HK (1) HK1010785A1 (ja)
HU (1) HU208439B (ja)
MC (1) MC2144A1 (ja)
TW (1) TW201754B (ja)
WO (1) WO1990003980A1 (ja)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN117362388A (zh) * 2023-04-10 2024-01-09 湖南中晟全肽生化有限公司 一种激活grp受体的多肽化合物及其用途

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2877775A (en) * 1957-12-23 1959-03-17 Preston M Hall Rotary type filing and abrading appliance
US5877277A (en) * 1987-09-24 1999-03-02 Biomeasure, Inc. Octapeptide bombesin analogs
AU618029B2 (en) * 1987-11-02 1991-12-12 Imperial Chemical Industries Plc Polypeptide compounds
US6218364B1 (en) 1988-06-20 2001-04-17 Scott L. Harbeson Fluorinated neurokinin A antagonists
US5830863A (en) * 1988-06-20 1998-11-03 Merrell Pharmaceuticals Inc. Neurokinin A antagonists
WO1991004040A1 (en) * 1989-09-15 1991-04-04 Biomeasure, Inc. Treatment of colon cancer
JPH04502629A (ja) * 1989-11-06 1992-05-14 フアルミタリア・カルロ・エルバ・エツセ・エルレ・エルレ 還元不可逆性ボンベシンアンタゴニスト
US5834433A (en) * 1990-07-26 1998-11-10 Merrell Pharmaceuticals Inc. Compounds and pharmaceutical uses of peptides of bombesin and GRP
ZA915740B (en) * 1990-07-26 1992-05-27 Merrell Dow Pharma Peptides
US5244883A (en) * 1990-11-29 1993-09-14 The Administrators Of The Tulane Educational Fund Nonapeptide bombesin antagonists
US5369094A (en) * 1990-11-29 1994-11-29 The Administrators Of The Tulane Educational Fund Polypeptide bombesin antagonists
JP3350701B2 (ja) * 1991-05-23 2002-11-25 メレルダウファーマスーティカルズ インコーポレイテッド ボンベシン類似体類
JPH07505865A (ja) * 1992-02-07 1995-06-29 メレルダウファーマスーティカルズ　インコーポレイテッド ボンベシンのフェニルアラニン類似体類
DE4320201A1 (de) * 1993-06-18 1995-01-12 Asta Medica Ag Verwendung von Cetrorelix und weiteren Nona- und Dekapeptiden zur Herstellung eines Arzneimittels zur Bekämpfung von Aids und zur Wachstumsstimulation
FR2739553B1 (fr) * 1995-10-06 1998-01-02 Oreal Utilisation d'antagonistes de la bradykinine pour stimuler ou induire la pousse des cheveux et/ou stopper leur chute
US6156725A (en) * 1996-08-16 2000-12-05 National Institute Of Immunology Drug for the treatment of cancer
US6492330B1 (en) 1996-08-16 2002-12-10 National Institute Of Immunology Antiangiogenic drugs
US7850947B2 (en) 2003-01-13 2010-12-14 Bracco Imaging S.P.A. Gastrin releasing peptide compounds
US8420050B2 (en) 2003-01-13 2013-04-16 Bracco Imaging S.P.A. Gastrin releasing peptide compounds
US7611692B2 (en) 2003-01-13 2009-11-03 Bracco Imaging S.P.A. Gastrin releasing peptide compounds
US7922998B2 (en) 2003-01-13 2011-04-12 Bracco Imaging S.P.A. Gastrin releasing peptide compounds
US7226577B2 (en) 2003-01-13 2007-06-05 Bracco Imaging, S. P. A. Gastrin releasing peptide compounds
KR20070108953A (ko) 2003-04-22 2007-11-13 소시에떼 더 콘세이유 더 레세르세 에 다플리까띠옹 시엔띠피끄, 에스.아.에스. 펩타이드 벡터
EP2289564A3 (en) * 2006-09-08 2012-11-14 Piramal Imaging SA Derivatives of aniline as precursors for F18-labeling
KR101642363B1 (ko) 2008-06-12 2016-07-25 입센 바이오이노베이션 리미티드 신경내분비계 질환의 억제
ES2732205T3 (es) 2008-06-12 2019-11-21 Ipsen Bioinnovation Ltd Proteínas de fusión para uso en el tratamiento del cáncer
GB0820970D0 (en) 2008-11-17 2008-12-24 Syntaxin Ltd Suppression of cancer
EP2198878A1 (en) 2008-12-18 2010-06-23 University Of Miami Polypeptide bombesin antagonists

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4207311A (en) 1977-07-18 1980-06-10 The Salk Institute For Biological Studies Peptides having analgesic and thermoregulative properties
US4331611A (en) 1979-12-21 1982-05-25 International Flavors & Fragrances Inc. Nitrile and uses of same in perfumes, colognes and perfumed articles
US4331661A (en) * 1980-10-03 1982-05-25 The Salk Institute For Biological Studies Bombesin analogs
US4613586A (en) 1984-04-19 1986-09-23 Board Of Trustees Of The Leland Stanford Junior University Gastrin releasing peptide-like peptides
US4803261A (en) * 1986-06-27 1989-02-07 The Administrators Of The Tulane Educational Fund Method for synthesizing a peptide containing a non-peptide

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN117362388A (zh) * 2023-04-10 2024-01-09 湖南中晟全肽生化有限公司 一种激活grp受体的多肽化合物及其用途

Also Published As

Publication number Publication date
AU638423B2 (en) 1993-07-01
DK66391A (da) 1991-06-14
HU896391D0 (en) 1991-07-29
DE68928667T2 (de) 1998-10-01
WO1990003980A1 (en) 1990-04-19
HU208439B (en) 1993-10-28
DE68928667D1 (de) 1998-06-10
FI104252B1 (fi) 1999-12-15
EP0438519A4 (en) 1991-10-30
AU4494989A (en) 1990-05-01
FI911780A0 (fi) 1991-04-12
HUT59420A (en) 1992-05-28
DK66391D0 (da) 1991-04-12
JP2919889B2 (ja) 1999-07-19
MC2144A1 (fr) 1992-02-19
KR900701827A (ko) 1990-12-04
HK1010785A1 (en) 1999-06-25
JPH04504406A (ja) 1992-08-06
EP0438519B1 (en) 1998-05-06
EP0438519A1 (en) 1991-07-31
ATE165836T1 (de) 1998-05-15
FI104252B (fi) 1999-12-15

Similar Documents

Publication Publication Date Title
TW201754B (ja)
JP2795449B2 (ja) 治療用ペプチド
JP3759748B2 (ja) 成長ホルモン放出性を有する化合物
US5877277A (en) Octapeptide bombesin analogs
KR100225679B1 (ko) 노나펩티드 봄베신 길항제
CN104395338B (zh) 人胰岛淀粉样多肽类似物
CA2064896A1 (en) Therapeutic peptides
WO2005077094A2 (en) Pancreatic polypeptide family motifs and polypeptides comprising the same
US5723578A (en) Peptide analogs of bombesin
JPH04503075A (ja) 結腸癌の処置
PL180372B1 (pl) Peptyd bedacy antagonista bombezyny oraz kompozycja farmaceutyczna zawierajaca ten peptyd PL PL PL PL PL PL
JPH03261800A (ja) ペプチド類
EP0531342A1 (en) Cyclized and linear therapeutic peptides
JPH06507633A (ja) 肝臓癌の治療
IE912671A1 (en) Peptides
AU703865B2 (en) Bombesin analogs
EP0737691A1 (en) Bombesin analogs
JP2010533129A (ja) 部位特異的なペグ化をされた直鎖状のサケカルシトニン類似体
CA1340988C (en) Therapeutic peptides
US6989371B1 (en) Bombesin analogs for treatment of cancer
AU622123C (en) Therapeutic peptides
RU2088592C1 (ru) Терапевтические пептиды или их фармацевтически приемлемые соли
JP3743794B2 (ja) ボンベシン類似体