TW201609634A - 吡咯啶基碸類視色素相關孤兒受體γ(RORγ)調節劑 - Google Patents
吡咯啶基碸類視色素相關孤兒受體γ(RORγ)調節劑 Download PDFInfo
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- TW201609634A TW201609634A TW104100097A TW104100097A TW201609634A TW 201609634 A TW201609634 A TW 201609634A TW 104100097 A TW104100097 A TW 104100097A TW 104100097 A TW104100097 A TW 104100097A TW 201609634 A TW201609634 A TW 201609634A
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- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
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- Animal Behavior & Ethology (AREA)
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- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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- Immunology (AREA)
- Pulmonology (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Dermatology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Transplantation (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201461923896P | 2014-01-06 | 2014-01-06 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TW201609634A true TW201609634A (zh) | 2016-03-16 |
Family
ID=52359012
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TW104100097A TW201609634A (zh) | 2014-01-06 | 2015-01-05 | 吡咯啶基碸類視色素相關孤兒受體γ(RORγ)調節劑 |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US20160326108A1 (OSRAM) |
| EP (1) | EP3092229B1 (OSRAM) |
| JP (1) | JP6530764B2 (OSRAM) |
| CN (1) | CN106061971B (OSRAM) |
| AR (1) | AR099029A1 (OSRAM) |
| CA (1) | CA2936116A1 (OSRAM) |
| EA (1) | EA030849B1 (OSRAM) |
| ES (1) | ES2669208T3 (OSRAM) |
| MX (1) | MX369347B (OSRAM) |
| TW (1) | TW201609634A (OSRAM) |
| WO (1) | WO2015103509A1 (OSRAM) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2015035278A1 (en) | 2013-09-09 | 2015-03-12 | Bristol-Myers Squibb Company | RORγ MODULATORS |
| JP6397488B2 (ja) | 2013-09-20 | 2018-09-26 | ブリストル−マイヤーズ スクイブ カンパニーBristol−Myers Squibb Company | RORγ調節因子 |
| EP3092215B1 (en) * | 2014-01-06 | 2018-10-17 | Bristol-Myers Squibb Company | Cyclohexyl sulfone ror gamma modulators |
| JP6574444B2 (ja) | 2014-01-06 | 2019-09-11 | ブリストル−マイヤーズ スクイブ カンパニーBristol−Myers Squibb Company | 炭素環式スルホンRORγ調節因子 |
| ES2705400T3 (es) | 2014-01-06 | 2019-03-25 | Bristol Myers Squibb Co | Sulfonas heterocíclicas como moduladores de ROR gamma |
| EP3212642B1 (en) | 2014-10-30 | 2019-10-30 | Janssen Pharmaceutica NV | Amide substituted thiazoles as modulators of rorgammat |
| US9861618B2 (en) | 2014-10-30 | 2018-01-09 | Janssen Pharmaceutica Nv | Thiazoles as modulators of RORγt |
| JOP20200117A1 (ar) | 2014-10-30 | 2017-06-16 | Janssen Pharmaceutica Nv | كحولات ثلاثي فلوروميثيل كمُعدلات للمستقبل النووي جاما تي المرتبط بحمض الريتيونَويك ROR?t |
| ES2887087T3 (es) | 2015-05-07 | 2021-12-21 | Bristol Myers Squibb Co | Sulfonas tricíclicas como moduladores ROR gamma |
| WO2017170830A1 (ja) * | 2016-03-31 | 2017-10-05 | 武田薬品工業株式会社 | 複素環化合物 |
| TW201803869A (zh) | 2016-04-27 | 2018-02-01 | 健生藥品公司 | 作為RORγT調節劑之6-胺基吡啶-3-基噻唑 |
| KR20190057388A (ko) | 2016-10-10 | 2019-05-28 | 브리스톨-마이어스 스큅 컴퍼니 | Ror 감마 조정제로서의 트리시클릭 술폰 |
| WO2018071620A1 (en) * | 2016-10-13 | 2018-04-19 | Bristol-Myers Squibb Company | Heterocyclic sulfones as ror gamma modulators |
| CA3042877A1 (en) | 2016-11-09 | 2018-05-17 | Bristol-Myers Squibb Company | Tricyclic sulfones as ror gamma modulators |
| EP3538522A1 (en) * | 2016-11-10 | 2019-09-18 | Bristol-Myers Squibb Company | Ror gamma modulators |
| EP3807261B1 (en) | 2018-06-18 | 2022-07-13 | Janssen Pharmaceutica NV | Pyridinyl pyrazoles as modulators of roryt |
| CN112292183A (zh) | 2018-06-18 | 2021-01-29 | 詹森药业有限公司 | 作为RORγt的调节剂的6-氨基吡啶-3-基吡唑 |
| JP2021528405A (ja) | 2018-06-18 | 2021-10-21 | ヤンセン ファーマシューティカ エヌ.ベー. | RORγtのモジュレータとしてのアミド置換チアゾール |
| CA3103770A1 (en) | 2018-06-18 | 2019-12-26 | Janssen Pharmaceutica Nv | Phenyl and pyridinyl substituted imidazoles as modulators of roryt |
| AU2019387370A1 (en) | 2018-11-30 | 2021-06-10 | Nuvation Bio Inc. | Pyrrole and pyrazole compounds and methods of use thereof |
| US12012374B2 (en) | 2019-05-13 | 2024-06-18 | Bristol-Myers Squibb Company | Agonists of ROR GAMMAt |
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| GB0108591D0 (en) * | 2001-04-05 | 2001-05-23 | Merck Sharp & Dohme | Therapeutic agents |
| CA2840060A1 (en) | 2011-06-27 | 2013-01-03 | Kyorin Pharmaceutical Co., Ltd. | Bridged bicyclic compounds for the treatment of bacterial infections |
| US20130190356A1 (en) * | 2011-12-22 | 2013-07-25 | Genentech, Inc. | Benzyl sulfonamide derivatives as rorc modulators |
| BR112014028023A2 (pt) * | 2012-05-08 | 2017-06-27 | Lycera Corp | composto, composição farmacêutica, método para tratar um distúrbio, método para reduzir a quantidade de il-17 em um indivíduo e método para inibir a atividade de rory |
| AR091279A1 (es) | 2012-06-08 | 2015-01-21 | Gilead Sciences Inc | Inhibidores macrociclicos de virus flaviviridae |
| WO2014028669A1 (en) * | 2012-08-15 | 2014-02-20 | Biogen Idec Ma Inc. | Novel compounds for modulation of ror-gamma activity |
| ES2705400T3 (es) | 2014-01-06 | 2019-03-25 | Bristol Myers Squibb Co | Sulfonas heterocíclicas como moduladores de ROR gamma |
| JP6574444B2 (ja) | 2014-01-06 | 2019-09-11 | ブリストル−マイヤーズ スクイブ カンパニーBristol−Myers Squibb Company | 炭素環式スルホンRORγ調節因子 |
| EP3092215B1 (en) | 2014-01-06 | 2018-10-17 | Bristol-Myers Squibb Company | Cyclohexyl sulfone ror gamma modulators |
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- 2015-01-05 WO PCT/US2015/010089 patent/WO2015103509A1/en not_active Ceased
- 2015-01-05 TW TW104100097A patent/TW201609634A/zh unknown
- 2015-01-05 US US15/109,719 patent/US20160326108A1/en not_active Abandoned
- 2015-01-05 CN CN201580011338.XA patent/CN106061971B/zh not_active Expired - Fee Related
- 2015-01-05 EA EA201691368A patent/EA030849B1/ru not_active IP Right Cessation
- 2015-01-05 CA CA2936116A patent/CA2936116A1/en not_active Abandoned
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| MX2016008845A (es) | 2016-09-07 |
| AR099029A1 (es) | 2016-06-22 |
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| MX369347B (es) | 2019-11-06 |
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| JP2017501236A (ja) | 2017-01-12 |
| CA2936116A1 (en) | 2015-07-09 |
| US20150191483A1 (en) | 2015-07-09 |
| US20160326108A1 (en) | 2016-11-10 |
| EP3092229A1 (en) | 2016-11-16 |
| EP3092229B1 (en) | 2018-03-28 |
| JP6530764B2 (ja) | 2019-06-12 |
| WO2015103509A1 (en) | 2015-07-09 |
| CN106061971A (zh) | 2016-10-26 |
| US9458171B2 (en) | 2016-10-04 |
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