MX369347B - Derivados de pirrolidinilsulfona y su uso como moduladores del receptor huerfano relacionado con retinoide gamma (ror gamma). - Google Patents

Derivados de pirrolidinilsulfona y su uso como moduladores del receptor huerfano relacionado con retinoide gamma (ror gamma).

Info

Publication number
MX369347B
MX369347B MX2016008845A MX2016008845A MX369347B MX 369347 B MX369347 B MX 369347B MX 2016008845 A MX2016008845 A MX 2016008845A MX 2016008845 A MX2016008845 A MX 2016008845A MX 369347 B MX369347 B MX 369347B
Authority
MX
Mexico
Prior art keywords
ror
pyrrolidinyl
sulfone derivatives
ror gamma
gamma modulators
Prior art date
Application number
MX2016008845A
Other languages
English (en)
Spanish (es)
Other versions
MX2016008845A (es
Inventor
G Murali Dhar T
Xiao Hai-Yun
Jiang Bin
Lu Zhonghui
Duan Jingwu
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Publication of MX2016008845A publication Critical patent/MX2016008845A/es
Publication of MX369347B publication Critical patent/MX369347B/es

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    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/12—Oxygen or sulfur atoms
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    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Pulmonology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Neurosurgery (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Transplantation (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pyridine Compounds (AREA)
MX2016008845A 2014-01-06 2015-01-05 Derivados de pirrolidinilsulfona y su uso como moduladores del receptor huerfano relacionado con retinoide gamma (ror gamma). MX369347B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201461923896P 2014-01-06 2014-01-06
PCT/US2015/010089 WO2015103509A1 (en) 2014-01-06 2015-01-05 Pyrrolidinyl sulfone derivatives and their use as ror gamma modulators

Publications (2)

Publication Number Publication Date
MX2016008845A MX2016008845A (es) 2016-09-07
MX369347B true MX369347B (es) 2019-11-06

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MX2016008845A MX369347B (es) 2014-01-06 2015-01-05 Derivados de pirrolidinilsulfona y su uso como moduladores del receptor huerfano relacionado con retinoide gamma (ror gamma).

Country Status (11)

Country Link
US (2) US20160326108A1 (OSRAM)
EP (1) EP3092229B1 (OSRAM)
JP (1) JP6530764B2 (OSRAM)
CN (1) CN106061971B (OSRAM)
AR (1) AR099029A1 (OSRAM)
CA (1) CA2936116A1 (OSRAM)
EA (1) EA030849B1 (OSRAM)
ES (1) ES2669208T3 (OSRAM)
MX (1) MX369347B (OSRAM)
TW (1) TW201609634A (OSRAM)
WO (1) WO2015103509A1 (OSRAM)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
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EP3044219A1 (en) 2013-09-09 2016-07-20 Bristol-Myers Squibb Company Rorgamma modulators
EP3046906B1 (en) 2013-09-20 2017-08-16 Bristol-Myers Squibb Company Ror gamma modulators
US9771320B2 (en) 2014-01-06 2017-09-26 Bristol-Myers Squibb Company Carbocyclic sulfone RORγ modulators
ES2704460T3 (es) 2014-01-06 2019-03-18 Bristol Myers Squibb Co Moduladores de ROR gamma de ciclohexilsulfona
EP3092221B1 (en) 2014-01-06 2018-10-17 Bristol-Myers Squibb Company Heterocyclic sulfones as ror-gamma modulators
LT3212641T (lt) 2014-10-30 2019-02-11 Janssen Pharmaceutica Nv Tiazolai, kaip roryt moduliatoriai
JOP20200117A1 (ar) 2014-10-30 2017-06-16 Janssen Pharmaceutica Nv كحولات ثلاثي فلوروميثيل كمُعدلات للمستقبل النووي جاما تي المرتبط بحمض الريتيونَويك ROR?t
US9845319B2 (en) 2014-10-30 2017-12-19 Janssen Pharmaceutiuca NV Amide substituted thiazoles as modulators of RORyt
WO2016179460A1 (en) 2015-05-07 2016-11-10 Bristol-Myers Squibb Company Tricyclic sulfones as rorϒ modulators
EP3438109B1 (en) * 2016-03-31 2021-08-25 Takeda Pharmaceutical Company Limited Heterocyclic compound
TW201803869A (zh) 2016-04-27 2018-02-01 健生藥品公司 作為ＲＯＲγＴ調節劑之６－胺基吡啶－３－基噻唑
EP3523279A1 (en) * 2016-10-10 2019-08-14 Bristol-Myers Squibb Company Tricyclic sulfones as ror gamma modulators
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MX2019005384A (es) * 2016-11-09 2019-08-12 Squibb Bristol Myers Co Sulfonas triciclicas como moduladores del receptor huerfano relacionado con retinoide (ror) gamma.
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