TW201605791A - Ｎｒ２ｂ之選擇性八氫-環戊二烯并［ｃ］吡咯負向調節劑 - Google Patents

Ｎｒ２ｂ之選擇性八氫-環戊二烯并［ｃ］吡咯負向調節劑 Download PDF

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TW201605791A
TW201605791A TW103133682A TW103133682A TW201605791A TW 201605791 A TW201605791 A TW 201605791A TW 103133682 A TW103133682 A TW 103133682A TW 103133682 A TW103133682 A TW 103133682A TW 201605791 A TW201605791 A TW 201605791A
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pyrrole
octahydrocyclopenta
hydroxy
benzyl
racemic
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TW103133682A
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Chinese (zh)
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大衛Ｒ 安德森
羅伯特Ａ 沃克曼
法蘭克Ｓ 曼奈迪
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美涅莫辛製藥公司
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Publication of TW201605791A publication Critical patent/TW201605791A/zh

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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
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    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
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    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
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TW103133682A 2013-09-26 2014-09-26 Ｎｒ２ｂ之選擇性八氫-環戊二烯并［ｃ］吡咯負向調節劑 TW201605791A (zh)

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ES2821896T3 (es) * 2015-08-05 2021-04-28 Indivior Uk Ltd Antagonistas del receptor de dopamina D3 que tienen una unidad estructural biciclo
WO2018232158A1 (en) * 2017-06-15 2018-12-20 Belite Bio, Inc. Methods of treating metabolic diseases with fused bicyclic pyrroles
CA3121850A1 (en) 2019-01-03 2020-07-09 Avive Solutions, Inc. Defibrillator communications architecture
EP4255419A1 (en) * 2020-12-04 2023-10-11 Novartis AG Dosage regimen for a nr2b-nmda receptor nam for the treatment of depression
CN117120053A (zh) * 2021-03-26 2023-11-24 诺华股份有限公司 新的环戊二烯并[c]吡咯NR2B负变构调节剂
CN117157072A (zh) * 2021-03-26 2023-12-01 诺华股份有限公司 新型环戊基并[c]吡咯NR2B负变构调节剂

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