CN105916843B - 八氢环戊二烯并[c]吡咯类选择性NR2B负性调节剂 - Google Patents

八氢环戊二烯并[c]吡咯类选择性NR2B负性调节剂 Download PDF

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CN105916843B
CN105916843B CN201480058773.3A CN201480058773A CN105916843B CN 105916843 B CN105916843 B CN 105916843B CN 201480058773 A CN201480058773 A CN 201480058773A CN 105916843 B CN105916843 B CN 105916843B
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pyrrol
hydroxy
octahydrocyclopenta
benzyl
pyrrole
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CN105916843A (zh
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D·R·安德森
R·A·沃尔科曼
F·S·曼尼缇
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Novartis AG
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Cordente Therapeutics
Luc Therapy Co ltd
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  • Pyrrole Compounds (AREA)
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  • Indole Compounds (AREA)
CN201480058773.3A 2013-09-26 2014-09-26 八氢环戊二烯并[c]吡咯类选择性NR2B负性调节剂 Active CN105916843B (zh)

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US61/883,050 2013-09-26
PCT/US2014/057800 WO2015048507A1 (en) 2013-09-26 2014-09-26 Selective octahydro-cyclopenta[c] pyrrole negative modulators of nr2b

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US9540324B2 (en) 2013-09-26 2017-01-10 Luc Therapeutics, Inc. Selective octahydro-cyclopenta[C] pyrrole negative modulators of NR2B
JO3579B1 (ar) * 2014-09-26 2020-07-05 Luc Therapeutics Inc مُعدِلات تفاغرية سالبة لمستقبل nr2b من المركب n-ألكيل أريل-5-أوكسي أريل-ثامن هيدرو-خماسي الحلقة [c] بيرول
AU2016303558B2 (en) * 2015-08-05 2020-08-06 Indivior Uk Limited Dopamine D3 receptor antagonists having a bicyclo moiety
WO2018232158A1 (en) * 2017-06-15 2018-12-20 Belite Bio, Inc. Methods of treating metabolic diseases with fused bicyclic pyrroles
US11452881B2 (en) 2019-01-03 2022-09-27 Avive Solutions, Inc. Defibrillator communications architecture
CA3203144A1 (en) * 2020-12-04 2022-06-09 Novartis Ag Dosage regimen for a nr2b-nmda receptor nam for the treatment of depression
WO2022204336A1 (en) * 2021-03-26 2022-09-29 Novartis Ag Novel cyclopental[c]pyrrol negative allosteric modulators of nr2b
US20240199576A1 (en) * 2021-03-26 2024-06-20 Novartis Ag Novel cyclopenta[c]pyrrol negative allosteric modulators of nr2b

Citations (8)

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