TW201238941A - Compounds that interact with glucokinase regulatory protein for the treatment of diabetes - Google Patents

Compounds that interact with glucokinase regulatory protein for the treatment of diabetes Download PDF

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Publication number
TW201238941A
TW201238941A TW100130164A TW100130164A TW201238941A TW 201238941 A TW201238941 A TW 201238941A TW 100130164 A TW100130164 A TW 100130164A TW 100130164 A TW100130164 A TW 100130164A TW 201238941 A TW201238941 A TW 201238941A
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Taiwan
Prior art keywords
phenyl
propanol
piperazinyl
trifluoro
crbrb
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TW100130164A
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English (en)
Chinese (zh)
Inventor
Kate Ashton
Michael David Bartberger
Yun-Xin Bo
Marian C Bryan
Michael Croghan
Christopher Harold Fotsch
Clarence Henderson Hale
Roxanne Kay Kunz
Longbin Liu
Nobuko Nishimura
Mark H Norman
Lewis Dale Pennington
Steve Fong Poon
Markian Myroslaw Stec
Jean David Joseph St Jr
Nuria A Tamayo
Christopher Michael Tegley
Kevin Chao Yang
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Amgen Inc
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Publication of TW201238941A publication Critical patent/TW201238941A/zh

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  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pyridine Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
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WO2014035872A1 (en) * 2012-08-27 2014-03-06 Amgen Inc. Tricyclic alkynes that interact with glucokinase regulatory protein
JP6102637B2 (ja) * 2013-08-22 2017-03-29 Jsr株式会社 芳香族ジハライド化合物、重合体、重合体組成物及び成形体
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US20240124400A1 (en) * 2019-10-11 2024-04-18 Duke University Lpxh targeting compounds, compositions thereof, and methods of making and using the same
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