TR201901826T4 - Il-4 ve/veya ıl-13'ün ilgili reseptörlerine bağlanmasını inhibe ederek belirli rahatsızlıkların önlenmesi ya da tedavi edilmesi için yöntemler. - Google Patents

Il-4 ve/veya ıl-13'ün ilgili reseptörlerine bağlanmasını inhibe ederek belirli rahatsızlıkların önlenmesi ya da tedavi edilmesi için yöntemler. Download PDF

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Publication number
TR201901826T4
TR201901826T4 TR2019/01826T TR201901826T TR201901826T4 TR 201901826 T4 TR201901826 T4 TR 201901826T4 TR 2019/01826 T TR2019/01826 T TR 2019/01826T TR 201901826 T TR201901826 T TR 201901826T TR 201901826 T4 TR201901826 T4 TR 201901826T4
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TR
Turkey
Prior art keywords
composition
lipocalin
use according
lipocalin mutein
fragment
Prior art date
Application number
TR2019/01826T
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English (en)
Turkish (tr)
Inventor
Hohlbaum Andreas
Audoly Laurent
Koller Beverly
Original Assignee
Astrazeneca Ab
Pieris Pharmaceuticals Gmbh
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Application filed by Astrazeneca Ab, Pieris Pharmaceuticals Gmbh filed Critical Astrazeneca Ab
Publication of TR201901826T4 publication Critical patent/TR201901826T4/tr

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0078Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/02Nasal agents, e.g. decongestants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/16Central respiratory analeptics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Otolaryngology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Dispersion Chemistry (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
TR2019/01826T 2011-12-13 2012-12-12 Il-4 ve/veya ıl-13'ün ilgili reseptörlerine bağlanmasını inhibe ederek belirli rahatsızlıkların önlenmesi ya da tedavi edilmesi için yöntemler. TR201901826T4 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201161570018P 2011-12-13 2011-12-13

Publications (1)

Publication Number Publication Date
TR201901826T4 true TR201901826T4 (tr) 2019-03-21

Family

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Application Number Title Priority Date Filing Date
TR2019/01826T TR201901826T4 (tr) 2011-12-13 2012-12-12 Il-4 ve/veya ıl-13'ün ilgili reseptörlerine bağlanmasını inhibe ederek belirli rahatsızlıkların önlenmesi ya da tedavi edilmesi için yöntemler.

Country Status (13)

Country Link
US (6) US9572863B2 (enExample)
EP (3) EP3842058B1 (enExample)
JP (5) JP6163162B2 (enExample)
CN (2) CN109432402B (enExample)
AU (1) AU2012350660B2 (enExample)
CA (1) CA2858962C (enExample)
DK (2) DK2790719T3 (enExample)
ES (2) ES2710384T3 (enExample)
HU (2) HUE054342T2 (enExample)
PL (2) PL2790719T3 (enExample)
SG (2) SG10201604566QA (enExample)
TR (1) TR201901826T4 (enExample)
WO (1) WO2013087660A1 (enExample)

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CN103038249B (zh) * 2010-06-08 2016-04-13 皮里斯股份公司 结合IL-4受体α的泪脂质运载蛋白突变蛋白
SG10201604566QA (en) * 2011-12-13 2016-07-28 Pieris Ag Methods for preventing or treating certain disorders by inhibiting binding of il-4 and/or il-13 to their respective receptors
CN113621050A (zh) 2014-05-22 2021-11-09 皮里斯制药有限公司 新型特异性结合多肽及其用途
EP3322433B1 (en) 2015-07-15 2023-05-31 Pieris Pharmaceuticals GmbH Novel proteins specific for lag-3
CN107474134B (zh) 2016-06-08 2021-07-27 苏州康乃德生物医药有限公司 用于结合白细胞介素4受体的抗体
RU2019122482A (ru) 2017-01-18 2021-02-19 Пирис Фармасьютикалс Гмбх Мутеины липокалина с аффинностью связывания в отношении lag-3
CA3059731A1 (en) 2017-04-21 2018-10-25 Kindred Biosciences, Inc. Il4/il13 receptor molecule for veterinary use
CN110746507B (zh) 2018-12-25 2020-06-26 江苏荃信生物医药有限公司 抗人白介素4受体α单克隆抗体及其应用
EP3946415A1 (en) * 2019-03-29 2022-02-09 Astrazeneca AB Lipocalin mutein for treatment of asthma
EP3946417A1 (en) * 2019-03-29 2022-02-09 Pieris Pharmaceuticals GmbH Inhaled administration of lipocalin muteins
CN116916945A (zh) 2020-12-18 2023-10-20 阿斯利康有限公司 用于治疗哮喘的脂质运载蛋白突变蛋白干粉制剂
CN115414467B (zh) * 2022-10-14 2023-06-06 中国人民解放军陆军军医大学第二附属医院 载脂蛋白d在制备治疗脑出血药物中的用途

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FR2649991B2 (fr) 1988-08-05 1994-03-04 Rhone Poulenc Sante Utilisation de derives stables du plasmide pkd1 pour l'expression et la secretion de proteines heterologues dans les levures du genre kluyveromyces
US5728553A (en) 1992-09-23 1998-03-17 Delta Biotechnology Limited High purity albumin and method of producing
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EP1377306A1 (en) 2001-03-09 2004-01-07 Dyax Corp. Serum albumin binding moieties
AU2001298053A1 (en) 2001-09-27 2003-04-14 Pieris Proteolab Ag Muteins of apolipoprotein D
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US7238661B2 (en) * 2002-05-24 2007-07-03 Agennix, Inc. Oral lactoferrin in the treatment of respiratory disorders
AU2003275958A1 (en) 2003-08-25 2005-03-10 Pieris Proteolab Ag Muteins of tear lipocalin
WO2005019254A1 (en) 2003-08-25 2005-03-03 Pieris Proteolab Ag Muteins of a bilin-binding protein with affinity for a given target
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SG10201604566QA (en) 2011-12-13 2016-07-28 Pieris Ag Methods for preventing or treating certain disorders by inhibiting binding of il-4 and/or il-13 to their respective receptors

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Publication number Publication date
PL2790719T3 (pl) 2019-05-31
JP2017149733A (ja) 2017-08-31
EP3842058A1 (en) 2021-06-30
HUE054342T2 (hu) 2021-08-30
US11382951B2 (en) 2022-07-12
US20200009223A1 (en) 2020-01-09
AU2012350660A1 (en) 2014-07-03
US20230021168A1 (en) 2023-01-19
JP6163162B2 (ja) 2017-07-12
DK2790719T3 (en) 2019-02-11
CN103998053B (zh) 2018-11-02
CN109432402B (zh) 2022-04-29
US9572863B2 (en) 2017-02-21
ES2863410T3 (es) 2021-10-11
CN103998053B9 (zh) 2020-07-21
CA2858962A1 (en) 2013-06-20
PL3453400T3 (pl) 2021-08-09
US10857202B2 (en) 2020-12-08
DK3453400T3 (da) 2021-04-06
CA2858962C (en) 2023-09-05
HUE042720T2 (hu) 2019-07-29
CN103998053A (zh) 2014-08-20
JP2015505303A (ja) 2015-02-19
ES2710384T3 (es) 2019-04-24
US10398754B2 (en) 2019-09-03
SG11201402992SA (en) 2014-07-30
JP2022084854A (ja) 2022-06-07
WO2013087660A1 (en) 2013-06-20
US20140357548A1 (en) 2014-12-04
EP3842058B1 (en) 2023-08-23
EP3453400B1 (en) 2021-01-20
JP6725447B2 (ja) 2020-07-15
US20170112900A1 (en) 2017-04-27
US20190030121A1 (en) 2019-01-31
SG10201604566QA (en) 2016-07-28
EP2790719A1 (en) 2014-10-22
CN109432402A (zh) 2019-03-08
EP2790719B1 (en) 2018-11-21
JP7441589B2 (ja) 2024-03-01
AU2012350660B2 (en) 2018-01-25
JP6889201B2 (ja) 2021-06-18
EP3453400A1 (en) 2019-03-13
US10016483B2 (en) 2018-07-10
JP2019116499A (ja) 2019-07-18
JP2020164532A (ja) 2020-10-08
US20210145934A1 (en) 2021-05-20

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