PL2790719T3 - Sposoby zapobiegania lub leczenia pewnych zaburzeń przez hamowanie wiązania IL-4 i/lub IL-13 z ich odpowiednimi receptorami - Google Patents

Sposoby zapobiegania lub leczenia pewnych zaburzeń przez hamowanie wiązania IL-4 i/lub IL-13 z ich odpowiednimi receptorami

Info

Publication number
PL2790719T3
PL2790719T3 PL12813295T PL12813295T PL2790719T3 PL 2790719 T3 PL2790719 T3 PL 2790719T3 PL 12813295 T PL12813295 T PL 12813295T PL 12813295 T PL12813295 T PL 12813295T PL 2790719 T3 PL2790719 T3 PL 2790719T3
Authority
PL
Poland
Prior art keywords
preventing
methods
inhibiting binding
treating certain
certain disorders
Prior art date
Application number
PL12813295T
Other languages
English (en)
Inventor
Andreas Hohlbaum
Laurent Audoly
Beverly Koller
Original Assignee
Astrazeneca Ab
Pieris Pharmaceuticals Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab, Pieris Pharmaceuticals Gmbh filed Critical Astrazeneca Ab
Publication of PL2790719T3 publication Critical patent/PL2790719T3/pl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0078Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/02Nasal agents, e.g. decongestants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/16Central respiratory analeptics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Otolaryngology (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Dispersion Chemistry (AREA)
  • Ophthalmology & Optometry (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
PL12813295T 2011-12-13 2012-12-12 Sposoby zapobiegania lub leczenia pewnych zaburzeń przez hamowanie wiązania IL-4 i/lub IL-13 z ich odpowiednimi receptorami PL2790719T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161570018P 2011-12-13 2011-12-13
PCT/EP2012/075146 WO2013087660A1 (en) 2011-12-13 2012-12-12 Methods for preventing or treating certain disorders by inhibiting binding of il-4 and/or il-13 to their respective receptors
EP12813295.8A EP2790719B1 (en) 2011-12-13 2012-12-12 Methods for preventing or treating certain disorders by inhibiting binding of il-4 and/or il-13 to their respective receptors.

Publications (1)

Publication Number Publication Date
PL2790719T3 true PL2790719T3 (pl) 2019-05-31

Family

ID=47552959

Family Applications (2)

Application Number Title Priority Date Filing Date
PL18197286T PL3453400T3 (pl) 2011-12-13 2012-12-12 Sposoby zapobiegania lub leczenia pewnych zaburzeń za pomocą hamowania wiązania IL-4 i/lub IL-13 z ich odpowiednimi receptorami
PL12813295T PL2790719T3 (pl) 2011-12-13 2012-12-12 Sposoby zapobiegania lub leczenia pewnych zaburzeń przez hamowanie wiązania IL-4 i/lub IL-13 z ich odpowiednimi receptorami

Family Applications Before (1)

Application Number Title Priority Date Filing Date
PL18197286T PL3453400T3 (pl) 2011-12-13 2012-12-12 Sposoby zapobiegania lub leczenia pewnych zaburzeń za pomocą hamowania wiązania IL-4 i/lub IL-13 z ich odpowiednimi receptorami

Country Status (13)

Country Link
US (6) US9572863B2 (pl)
EP (3) EP3842058B1 (pl)
JP (5) JP6163162B2 (pl)
CN (2) CN109432402B (pl)
AU (1) AU2012350660B2 (pl)
CA (1) CA2858962C (pl)
DK (2) DK2790719T3 (pl)
ES (2) ES2863410T3 (pl)
HU (2) HUE042720T2 (pl)
PL (2) PL3453400T3 (pl)
SG (2) SG10201604566QA (pl)
TR (1) TR201901826T4 (pl)
WO (1) WO2013087660A1 (pl)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
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RS58839B1 (sr) * 2010-06-08 2019-07-31 Pieris Pharmaceuticals Gmbh Muteini lipokalina u suzama koji vezuju il-4 r alfa
HUE042720T2 (hu) 2011-12-13 2019-07-29 Pieris Pharmaceuticals Gmbh Eljárás bizonyos rendellenességek megelõzésére vagy kezelésére IL-4 és/vagy IL-13 saját receptorához történõ kötõdésének gátlása révén
EP3145945B1 (en) * 2014-05-22 2020-07-15 Pieris Pharmaceuticals GmbH Novel specific-binding polypeptides and uses thereof
US10501510B2 (en) 2015-07-15 2019-12-10 Pieris Pharmaceuticals Gmbh Muteins of human tear lipocalin capable of binding lymphocyte-activation gene 3 (LAG-3) and methods of use thereof
CN107474134B (zh) * 2016-06-08 2021-07-27 苏州康乃德生物医药有限公司 用于结合白细胞介素4受体的抗体
WO2018134274A1 (en) 2017-01-18 2018-07-26 Pieris Pharmaceuticals Gmbh Lipocalin muteins with binding affinity for lag-3
MX2019012570A (es) 2017-04-21 2019-12-02 Kindred Biosciences Inc Molecula del receptor de interleucina 4/interleucina 13 para uso veterinario.
CN111514292B (zh) * 2018-12-25 2023-06-20 江苏荃信生物医药股份有限公司 抗人白介素4受体α单克隆抗体的制药用途
CN113613669A (zh) * 2019-03-29 2021-11-05 阿斯利康有限公司 用于治疗哮喘的脂质运载蛋白突变蛋白
EP3946417A1 (en) 2019-03-29 2022-02-09 Pieris Pharmaceuticals GmbH Inhaled administration of lipocalin muteins
PE20240799A1 (es) 2020-12-18 2024-04-18 Astrazeneca Ab Formulacion de polvo seco de muteina de lipocalina para el tratamiento del asma
CN115414467B (zh) * 2022-10-14 2023-06-06 中国人民解放军陆军军医大学第二附属医院 载脂蛋白d在制备治疗脑出血药物中的用途

Family Cites Families (25)

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JPH01215289A (ja) 1988-02-22 1989-08-29 Toa Nenryo Kogyo Kk 遺伝子組換えによる正常ヒト血清アルブミンaの製造方法
FR2649991B2 (fr) 1988-08-05 1994-03-04 Rhone Poulenc Sante Utilisation de derives stables du plasmide pkd1 pour l'expression et la secretion de proteines heterologues dans les levures du genre kluyveromyces
US5728553A (en) 1992-09-23 1998-03-17 Delta Biotechnology Limited High purity albumin and method of producing
DE4425255A1 (de) 1994-07-16 1996-01-18 Asta Medica Ag Formulierung zur inhalativen Applikation
US5908621A (en) 1995-11-02 1999-06-01 Schering Corporation Polyethylene glycol modified interferon therapy
US6446467B1 (en) 1997-07-29 2002-09-10 Physical Optics Corporation Monolithic glass light shaping diffuser and method for its production
DE19742706B4 (de) 1997-09-26 2013-07-25 Pieris Proteolab Ag Lipocalinmuteine
SI1087778T1 (sl) 1998-06-08 2006-02-28 Hoffmann La Roche Uporaba peg-ifn-alfa in ribavirina za zdravljenje kronicnega hepatitisa c
US6403564B1 (en) 1998-10-16 2002-06-11 Schering Corporation Ribavirin-interferon alfa combination therapy for eradicating detectable HCV-RNA in patients having chronic hepatitis C infection
DE19926068C1 (de) 1999-06-08 2001-01-11 Arne Skerra Muteine des Bilin-Bindungsproteins
DE10043509A1 (de) 2000-09-01 2002-03-14 Asta Medica Ag Feste Peptidzubereitungen für die Inhalation und deren Herstellung
US7211395B2 (en) 2001-03-09 2007-05-01 Dyax Corp. Serum albumin binding moieties
WO2003029462A1 (en) 2001-09-27 2003-04-10 Pieris Proteolab Ag Muteins of human neutrophil gelatinase-associated lipocalin and related proteins
EP1430136A1 (en) 2001-09-27 2004-06-23 Pieris ProteoLab AG Muteins of apolipoprotein d
WO2003099207A2 (en) * 2002-05-24 2003-12-04 Agennix Incorporated Oral lactoferrin in the treatment of respiratory disorders
AU2003275958A1 (en) 2003-08-25 2005-03-10 Pieris Proteolab Ag Muteins of tear lipocalin
EP1658308A1 (en) 2003-08-25 2006-05-24 Pieris ProteoLab AG Muteins of a bilin-binding protein with affinity for a given target
RU2389796C2 (ru) 2003-08-29 2010-05-20 Аэровэнс, Инк. Модифицированный антагонист рецептора il-4 и предназначенный для его получения очищенный полинуклеотид
WO2006056464A2 (en) 2004-11-26 2006-06-01 Pieris Ag Compound with affinity for the cytotoxic t lymphocyte-associated antigen (ctla-4)
US20070212703A1 (en) 2005-09-27 2007-09-13 Stemmer Willem P Proteinaceous pharmaceuticals and uses thereof
WO2007107563A2 (en) 2006-03-20 2007-09-27 Technische Universität München Muteins of tear lipocalin with affinity for the t-cell coreceptor cd4
DK2046820T3 (da) * 2006-08-01 2011-02-07 Pieris Ag Muteiner af tåre-lipocalin og fremgangsmåder til opnåelse deraf
AU2008274938A1 (en) * 2007-07-11 2009-01-15 Aerovance, Inc. Pharmaceutical polypeptide dry powder aerosol formulation and method of preparation
RS58839B1 (sr) 2010-06-08 2019-07-31 Pieris Pharmaceuticals Gmbh Muteini lipokalina u suzama koji vezuju il-4 r alfa
HUE042720T2 (hu) 2011-12-13 2019-07-29 Pieris Pharmaceuticals Gmbh Eljárás bizonyos rendellenességek megelõzésére vagy kezelésére IL-4 és/vagy IL-13 saját receptorához történõ kötõdésének gátlása révén

Also Published As

Publication number Publication date
EP2790719A1 (en) 2014-10-22
DK2790719T3 (en) 2019-02-11
US20190030121A1 (en) 2019-01-31
US9572863B2 (en) 2017-02-21
JP6163162B2 (ja) 2017-07-12
ES2710384T3 (es) 2019-04-24
CA2858962C (en) 2023-09-05
CN103998053B9 (zh) 2020-07-21
AU2012350660A1 (en) 2014-07-03
CA2858962A1 (en) 2013-06-20
US20140357548A1 (en) 2014-12-04
HUE054342T2 (hu) 2021-08-30
JP6725447B2 (ja) 2020-07-15
US11382951B2 (en) 2022-07-12
US20200009223A1 (en) 2020-01-09
ES2863410T3 (es) 2021-10-11
TR201901826T4 (tr) 2019-03-21
JP7441589B2 (ja) 2024-03-01
HUE042720T2 (hu) 2019-07-29
US10857202B2 (en) 2020-12-08
SG10201604566QA (en) 2016-07-28
US20210145934A1 (en) 2021-05-20
SG11201402992SA (en) 2014-07-30
EP2790719B1 (en) 2018-11-21
PL3453400T3 (pl) 2021-08-09
US20170112900A1 (en) 2017-04-27
CN109432402A (zh) 2019-03-08
EP3842058A1 (en) 2021-06-30
JP2017149733A (ja) 2017-08-31
US10016483B2 (en) 2018-07-10
US20230021168A1 (en) 2023-01-19
CN103998053B (zh) 2018-11-02
AU2012350660B2 (en) 2018-01-25
JP2015505303A (ja) 2015-02-19
EP3842058B1 (en) 2023-08-23
EP3453400B1 (en) 2021-01-20
CN103998053A (zh) 2014-08-20
DK3453400T3 (da) 2021-04-06
CN109432402B (zh) 2022-04-29
JP2019116499A (ja) 2019-07-18
WO2013087660A1 (en) 2013-06-20
US10398754B2 (en) 2019-09-03
EP3453400A1 (en) 2019-03-13
JP2022084854A (ja) 2022-06-07
JP2020164532A (ja) 2020-10-08
JP6889201B2 (ja) 2021-06-18

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